Karl E Griswold

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 16

Top Venues

ACS synthetic biology

Antimicrobial agents and chemotherapy

PLoS computational biology

Proceedings of the National Academy of Sciences of the United States of America

Dartmouth College

University of Texas at Austin (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Dartmouth College

United States

Associate Professor :: Thayer School of Engineering

Dartmouth College

United States

Assistant Professor :: Thayer School of Engineering

Huntsman Corp

United States

Applications Chemist

Thermo Electron

United States

Final Test Technician :: GCQ Production

Education History

University of Texas at Austin

United States

PHD :: Chemistry/Biochemistry

Texas State University San Marcos

United States

BSC :: Chemistry

Publications

Yongliang Fang, Andrew Y Chang, Deeptak Verma, Shin-Ichiro Miyashita, Susan Eszterhas, Pyung-Gang Lee, Yi Shen, Lydia R Davis, Min Dong, Chris Bailey-Kellogg, Karl E Griswold
Functional Deimmunization of Botulinum Neurotoxin Protease Domain via Computationally Driven Library Design and Ultrahigh-Throughput Screening. ACS synthetic biology 12 (1) (2023)
Yongliang Fang, Andrew Y Chang, Deeptak Verma, Shin-Ichiro Miyashita, Susan Eszterhas, Pyung-Gang Lee, Yi Shen, Lydia R Davis, Min Dong, Chris Bailey-Kellogg, Karl E Griswold
Functional Deimmunization of Botulinum Neurotoxin Protease Domain via Computationally Driven Library Design and Ultrahigh-Throughput Screening. ACS synthetic biology 12 (1) (2023)
Yongliang Fang, Andrew Y Chang, Deeptak Verma, Shin-Ichiro Miyashita, Susan Eszterhas, Pyung-Gang Lee, Yi Shen, Lydia R Davis, Min Dong, Chris Bailey-Kellogg, Karl E Griswold
Functional Deimmunization of Botulinum Neurotoxin Protease Domain via Computationally Driven Library Design and Ultrahigh-Throughput Screening. ACS synthetic biology (2023)
Yongliang Fang, Andrew Y Chang, Deeptak Verma, Shin-Ichiro Miyashita, Susan Eszterhas, Pyung-Gang Lee, Yi Shen, Lydia R Davis, Min Dong, Chris Bailey-Kellogg, Karl E Griswold
Functional Deimmunization of Botulinum Neurotoxin Protease Domain via Computationally Driven Library Design and Ultrahigh-Throughput Screening. ACS synthetic biology 12 (1) (2023)
Yongliang Fang, Andrew Y Chang, Deeptak Verma, Shin-Ichiro Miyashita, Susan Eszterhas, Pyung-Gang Lee, Yi Shen, Lydia R Davis, Min Dong, Chris Bailey-Kellogg, Karl E Griswold
Functional Deimmunization of Botulinum Neurotoxin Protease Domain via Computationally Driven Library Design and Ultrahigh-Throughput Screening. ACS synthetic biology 12 (1) (2023)
Yongliang Fang, Andrew Y Chang, Deeptak Verma, Shin-Ichiro Miyashita, Susan Eszterhas, Pyung-Gang Lee, Yi Shen, Lydia R Davis, Min Dong, Chris Bailey-Kellogg, Karl E Griswold
Functional Deimmunization of Botulinum Neurotoxin Protease Domain via Computationally Driven Library Design and Ultrahigh-Throughput Screening. ACS synthetic biology 12 (1) (2023)
Yongliang Fang, Andrew Y Chang, Deeptak Verma, Shin-Ichiro Miyashita, Susan Eszterhas, Pyung-Gang Lee, Yi Shen, Lydia R Davis, Min Dong, Chris Bailey-Kellogg, Karl E Griswold
Functional Deimmunization of Botulinum Neurotoxin Protease Domain via Computationally Driven Library Design and Ultrahigh-Throughput Screening. ACS synthetic biology 12 (1) (2023)
Yongliang Fang, Jack R Kirsch, Liang Li, Seth A Brooks, Spencer Heim, Cynthia Tan, Susan Eszterhas, Hao D Cheng, Hongliang Zhao, Yan Q Xiong, Karl E Griswold
Deimmunized Lysostaphin Synergizes with Small-Molecule Chemotherapies and Resensitizes Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics. Antimicrobial agents and chemotherapy 65 (3) (2021)
Spencer J Mitchell, Deeptak Verma, Karl E Griswold, Chris Bailey-Kellogg
Building blocks and blueprints for bacterial autolysins. PLoS computational biology 17 (4) (2021)
Jacob M Furlon, Spencer J Mitchell, Chris Bailey-Kellogg, Karl E Griswold
Bioinformatics-driven discovery of novel Clostridioides difficile lysins and experimental comparison with highly active benchmarks. Biotechnology and bioengineering 118 (7) (2021)
Hongliang Zhao, Susan Eszterhas, Jacob Furlon, Hao Cheng, Karl E Griswold
Electrostatic-Mediated Affinity Tuning of Lysostaphin Accelerates Bacterial Lysis Kinetics and Enhances In Vivo Efficacy. Antimicrobial agents and chemotherapy 65 (4) (2021)
Ian Blumenthal, Lydia R Davis, Chet M Berman, Karl E Griswold
Nonclassical antagonism between human lysozyme and AMPs against Pseudomonas aeruginosa. FEBS open bio 11 (3) (2021)
Jung Kyoon Choi, Sukyo Jeong, Jung-Min Choi, Christian Ndong, Karl E Griswold, Chris Bailey-Kellogg, Hak-Sung Kim
Computer-guided binding mode identification and affinity improvement of an LRR protein binder without structure determination. PLoS computational biology 16 (8) (2020)
Hongliang Zhao, Seth A Brooks, Susan Eszterhas, Spencer Heim, Liang Li, Yan Q Xiong, Yongliang Fang, Jack R Kirsch, Deeptak Verma, Chris Bailey-Kellogg, Karl E Griswold
Globally deimmunized lysostaphin evades human immune surveillance and enables highly efficacious repeat dosing. Science advances 6 (36) (2020)
Laura Bricio-Moreno, Victoria H Sheridan, Ian Goodhead, Stuart Armstrong, Janet K L Wong, Elaine M Waters, Joscelyn Sarsby, Stavros Panagiotou, James Dunn, Adrita Chakraborty, Yongliang Fang, Karl E Griswold, Craig Winstanley, Joanne L Fothergill, Aras Kadioglu, Daniel R Neill
Evolutionary trade-offs associated with loss of PmrB function in host-adapted Pseudomonas aeruginosa. Nature communications 9 (1) (2018)
Regina S Salvat, Deeptak Verma, Andrew S Parker, Jack R Kirsch, Seth A Brooks, Chris Bailey-Kellogg, Karl E Griswold
Computationally optimized deimmunization libraries yield highly mutated enzymes with low immunogenicity and enhanced activity. Proceedings of the National Academy of Sciences of the United States of America 114 (26) (2017)

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Publication Activity (10 Years)

Top Topics

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Karl E Griswold