Antimicrobial agents and chemotherapy

Keyphrases

Publications

volume 68, number 8, 2024

Phyllis Awor, Romain Coppée, Nimol Khim, Laurine Rondepierre, Camille Roesch, Chanra Khean, Chanvong Kul, Rotha Eam, Thornleaksmey Lorn, Proscovia Athieno, Joseph Kimera, Betty Balikagala, Emmanuel I Odongo-Aginya, Denis A Anywar, Toshihiro Mita, Jérôme Clain, Pascal Ringwald, Aita Signorell, Christian Lengeler, Christian Burri, Frédéric Ariey, Manuel W Hetzel, Benoit Witkowski
Indigenous emergence and spread of kelch13 C469Y artemisinin-resistant Plasmodium falciparum in Uganda. Antimicrobial agents and chemotherapy 68 (8) (2024)
Valeria Gigante, Richard A Alm, Daniela Melchiorri, Tamarie Rocke, César A Arias, Lloyd Czaplewski, Prabhavathi Fernandes, François Franceschi, Stephan Harbarth, Roman Kozlov, Christian Lienhardt, Norio Ohmagari, Lesley A Ogilvie, Mical Paul, John H Rex, Lynn L Silver, Melvin Spigelman, Hatim Sati, Alexandra M Cameron
Multi-year analysis of the global preclinical antibacterial pipeline: trends and gaps. Antimicrobial agents and chemotherapy 68 (8) (2024)
Shougen Sumiyoshi
Concerns about the interpretation of treatment effects. Antimicrobial agents and chemotherapy 68 (8) (2024)
Pradeep Annamalai Subramani, Phornpimon Tipthara, Surendra Kumar Kolli, Justin Nicholas, Samantha J Barnes, Madison M Ogbondah, Kevin C Kobylinski, Joel Tarning, John H Adams
Efficacy of ivermectin and its metabolites against Plasmodium falciparum liver stages in primary human hepatocytes. Antimicrobial agents and chemotherapy 68 (8) (2024)
Maria-Ioanna Beredaki, Maiken Cavling Arendrup, Spyros Pournaras, Joseph Meletiadis
Comparative pharmacodynamics and dose optimization of liposomal amphotericin B against Candida species in an in vitro pharmacokinetic/pharmacodynamic model. Antimicrobial agents and chemotherapy 68 (8) (2024)
Manna Semere Gebreyesus, Roeland E Wasmann, Helen M McIlleron, Regina Oladokun, Prosper Okonkwo, Lubbe Wiesner, Paolo Denti, Holly E Rawizza
Population pharmacokinetics of rifabutin among HIV/TB co-infected children on lopinavir/ritonavir-based antiretroviral therapy. Antimicrobial agents and chemotherapy 68 (8) (2024)
Segolene Simeon, Maria Garcia-Cremades, Radojka M Savic, Belen P Solans
Pharmacokinetic-pharmacodynamic modeling of tuberculosis time to positivity and colony-forming unit to assess the response to dose-ranging linezolid. Antimicrobial agents and chemotherapy 68 (8) (2024)
Cordelia Ihl, J Giai, M Barbado, A Paris, S Touati, J P Alcaraz, S Tanguy, C Leroy, A Lehmann, B Degano, M Gavard, P Bedouch, P Pavese, A Moreau-Gaudry, M Roustit, François Boucher, P Cinquin, J P Brion
H 2 inhalation therapy in patients with moderate COVID-19 (H 2 COVID): a prospective ascending-dose phase I clinical trial. Antimicrobial agents and chemotherapy 68 (8) (2024)
Jacob Strahilevitz, Yair Motro, Violeta Temper, Diana Merezhko, Oshrat Ayalon, Yehonatan Bar Moshe, Margaret M C Lam, Kathryn E Holt, Moran-Gilad J
In vivo selection of carbapenem resistance during persistent Klebsiella pneumoniae sequence type 395 bloodstream infection due to OmpK36 deletion. Antimicrobial agents and chemotherapy 68 (8) (2024)
Dana S Clutter, Zahra Samiezade-Yazd, Jamila H Champsi, Jeffrey Schapiro, Michael J Silverberg
Antibiotic duration and route for treatment of adults with uncomplicated streptococcal bloodstream infections: a retrospective study in a large healthcare system. Antimicrobial agents and chemotherapy 68 (8) (2024)
Jeffrey T Wieczorkiewicz, Andrew M Skinner, Adam Cheknis, Laurica A Petrella, Vanessa W Stevens, Lorinda M Wright, Dale N Gerding, Stuart Johnson
Epidemiology of Clostridioides difficile infection at one hospital 10 years after an outbreak of the epidemic C. difficile strain BI/027: changing strain prevalence, antimicrobial susceptibilities, and patient antibiotic exposures. Antimicrobial agents and chemotherapy 68 (8) (2024)
Yibing Ma, Mattia Pirolo, Bimal Jana, Viktor Hundtofte Mebus, Luca Guardabassi
The intrinsic macrolide resistome of Escherichia coli . Antimicrobial agents and chemotherapy 68 (8) (2024)
Randolph P Matthews, Yang Liu, Catherine Matthews, Kristin L Butterfield, Terry O'Reilly, S Aubrey Stoch, Marian Iwamoto
Thorough QT/QTc study to evaluate the effect of a single supratherapeutic dose of islatravir on QTc interval prolongation in healthy adults. Antimicrobial agents and chemotherapy 68 (8) (2024)
Adam H Roberts, Christopher W Moon, Valwynne Faulkner, Sharon L Kendall, Simon J Waddell, Joanna Bacon
EfpA is required for regrowth of Mycobacterium tuberculosis following isoniazid exposure. Antimicrobial agents and chemotherapy 68 (8) (2024)
Mads Lindholm Kurtzhals, Anders Norman, Erik Svensson, Troels Lillebaek, Dorte Bek Folkvardsen
Applying whole genome sequencing to predict phenotypic drug resistance in Mycobacterium tuberculosis : leveraging 20 years of nationwide data from Denmark. Antimicrobial agents and chemotherapy 68 (8) (2024)
Daisuke Ono, Anna Cmolik, Christopher R Bethel, Yoshikazu Ishii, Salvador Iván Drusin, Diego Martín Moreno, Alejandro J Vila, Robert A Bonomo, María Fernanda Mojica
The interaction of the azetidine thiazole side chain with the active site loop (ASL) 3 drives the evolution of IMP metallo-β-lactamase against tebipenem. Antimicrobial agents and chemotherapy 68 (8) (2024)
Prajna Parimita Kar, Prasanna Babu Araveti, Kanika Saxena, Atlanta Borah, Puran Singh Sijwali, Anand Srivastava
Cimicifugin, a broad-spectrum inhibitor of Theileria annulata and Plasmodium falciparum CDK7. Antimicrobial agents and chemotherapy 68 (8) (2024)
Michael R Hodges, Eric Ople, Philip Evans, A J Andre Pantophlet, Jessica Richardson, Dylan Williams, Sakambari Tripathy, Margaret Tawadrous, Abhijeet Jakate
A phase 1 open label study to assess the human mass balance and metabolite profile of 14 C-fosmanogepix, a novel Gwt-1 inhibitor in healthy male participants. Antimicrobial agents and chemotherapy 68 (8) (2024)
Sean Wasserman, Rosleine Antilus-Sainte, Noha Abdelgawad, Narineh M Odjourian, Melissa Cristaldo, Maureen Dougher, Firat Kaya, Matthew Zimmerman, Paolo Denti, Martin Gengenbacher
Rifabutin central nervous system concentrations in a rabbit model of tuberculous meningitis. Antimicrobial agents and chemotherapy 68 (8) (2024)
Yan Sun, Kaixi Zhang, May Delos Santos, Carmen J E Pee, Yanmeng Yang, Meiqi Kang, Sung Jae Shin, Mary B Chan-Park, Kevin Pethe
An optimized cyclophosphamide-treated mouse model of Mycobacterium abscessus pulmonary infection. Antimicrobial agents and chemotherapy 68 (8) (2024)
Sanne van der Niet, Keith D Green, Irene M Schimmel, Jordy de Bakker, Bastiaan Lodder, Eric A Reits, Sylvie Garneau-Tsodikova, Nicole N van der Wel
Zafirlukast induces DNA condensation and has bactericidal effect on replicating Mycobacterium abscessus . Antimicrobial agents and chemotherapy 68 (8) (2024)
Jesal Shah, Barbara W Trautner, Kiara Olmeda, Lindsey A Laytner, Fabrizia Faustinella, Michael K Paasche-Orlow, Larissa Grigoryan
A survey of patient practices regarding leftover antibiotics reveals a potential source of antibiotic overuse. Antimicrobial agents and chemotherapy 68 (8) (2024)
Giacomo Ponta, Valentina Morena, Martina Strano, Chiara Molteni, Silvia Pontiggia, Erica Michela Cavalli, Anna Grancini, Carola Mauri, Antonella Castagna, Andrea Galanti, Stefania Piconi
Safety of rezafungin as a long-term treatment option in two patients with complicated fungal infections: two cases from Lecco Hospital (Italy). Antimicrobial agents and chemotherapy 68 (8) (2024)
Randolph P Matthews, Yang Liu, Catherine Matthews, Kristin L Butterfield, Terry O'Reilly, S Aubrey Stoch, Marian Iwamoto
Thorough QT/QTc study to evaluate the effect of a single supratherapeutic dose of islatravir on QTc interval prolongation in healthy adults. Antimicrobial agents and chemotherapy 68 (8) (2024)
Jeffrey T Wieczorkiewicz, Andrew M Skinner, Adam Cheknis, Laurica A Petrella, Vanessa W Stevens, Lorinda M Wright, Dale N Gerding, Stuart Johnson
Epidemiology of Clostridioides difficile infection at one hospital 10 years after an outbreak of the epidemic C. difficile strain BI/027: changing strain prevalence, antimicrobial susceptibilities, and patient antibiotic exposures. Antimicrobial agents and chemotherapy 68 (8) (2024)
Maria-Ioanna Beredaki, Maiken Cavling Arendrup, Spyros Pournaras, Joseph Meletiadis
Comparative pharmacodynamics and dose optimization of liposomal amphotericin B against Candida species in an in vitro pharmacokinetic/pharmacodynamic model. Antimicrobial agents and chemotherapy 68 (8) (2024)
Pradeep Annamalai Subramani, Phornpimon Tipthara, Surendra Kumar Kolli, Justin Nicholas, Samantha J Barnes, Madison M Ogbondah, Kevin C Kobylinski, Joel Tarning, John H Adams
Efficacy of ivermectin and its metabolites against Plasmodium falciparum liver stages in primary human hepatocytes. Antimicrobial agents and chemotherapy 68 (8) (2024)
Jesal Shah, Barbara W Trautner, Kiara Olmeda, Lindsey A Laytner, Fabrizia Faustinella, Michael K Paasche-Orlow, Larissa Grigoryan
A survey of patient practices regarding leftover antibiotics reveals a potential source of antibiotic overuse. Antimicrobial agents and chemotherapy 68 (8) (2024)
Yibing Ma, Mattia Pirolo, Bimal Jana, Viktor Hundtofte Mebus, Luca Guardabassi
The intrinsic macrolide resistome of Escherichia coli . Antimicrobial agents and chemotherapy 68 (8) (2024)
Dana S Clutter, Zahra Samiezade-Yazd, Jamila H Champsi, Jeffrey Schapiro, Michael J Silverberg
Antibiotic duration and route for treatment of adults with uncomplicated streptococcal bloodstream infections: a retrospective study in a large healthcare system. Antimicrobial agents and chemotherapy 68 (8) (2024)
Wesley D Kufel, Kumar Priyank
Oral flucytosine dosing in peritoneal dialysis. Antimicrobial agents and chemotherapy 68 (8) (2024)
Max W Adelman, David R Andes
Case Commentary: Extending our therapeutic range against multidrug-resistant Candida . Antimicrobial agents and chemotherapy 68 (8) (2024)
Stephanie Kabeche, Thomas Braukmann, Jon Doenier, Thomas R Meister, Ellen Yeh
A picomolar inhibitor of the Plasmodium falciparum IPP pathway. Antimicrobial agents and chemotherapy 68 (8) (2024)
Jacob Strahilevitz, Yair Motro, Violeta Temper, Diana Merezhko, Oshrat Ayalon, Yehonatan Bar Moshe, Margaret M C Lam, Kathryn E Holt, Moran-Gilad J
In vivo selection of carbapenem resistance during persistent Klebsiella pneumoniae sequence type 395 bloodstream infection due to OmpK36 deletion. Antimicrobial agents and chemotherapy 68 (8) (2024)
Isa Faghihi, Victoria C Yan
Remdesivir treatment does not reduce viral titers in patients with COVID-19. Antimicrobial agents and chemotherapy 68 (8) (2024)
Que Chi Truong-Bolduc, Y Wang, B G Lawton, H Brown Harding, L M Yonker, J M Vyas, David C Hooper
Phenazine-1 carboxylic acid of Pseudomonas aeruginosa induces the expression of Staphylococcus aureus Tet38 MDR efflux pump and mediates resistance to phenazines and antibiotics. Antimicrobial agents and chemotherapy 68 (8) (2024)
Shafinaz Eisha, Amanda J Morris, Isaac Martin, Yvonne C W Yau, Hartmut Grasemann, Valerie Waters
Effect of L-arginine on cystic fibrosis Pseudomonas aeruginosa biofilms. Antimicrobial agents and chemotherapy 68 (8) (2024)
Luis E Tavernelli, Victoria L Alonso, Imanol Peña, Elvio Rodríguez Araya, Romina Manarin, Juan Cantizani, Julio Martin, Juan Salamanca, Paul Bamborough, Felix Calderón, Raquel Gabarro, Esteban Serra
Identification of novel bromodomain inhibitors of Trypanosoma cruzi bromodomain factor 2 ( Tc BDF2) using a fluorescence polarization-based high-throughput assay. Antimicrobial agents and chemotherapy 68 (8) (2024)
Janet Conway, Ronald E Delanois, Michael A Mont, Alexandra Stavrakis, Edward McPherson, Edward Stolarski, Stephen Incavo, Daniel Oakes, Ralph Salvagno, John S Adams, Adriane Kisch-Hancock, Edgar Tenorio, Anton Leighton, Stefan Ryser, Lawrence M Kauvar, Nicholas M Bernthal
Phase 1 study of the pharmacokinetics and clinical proof-of-concept activity of a biofilm-disrupting human monoclonal antibody in patients with chronic prosthetic joint infection of the knee or hip. Antimicrobial agents and chemotherapy 68 (8) (2024)
Binayak Rimal, Christopher K Lippincott, Chandra M Panthi, Yi Xie, Tiffany R Keepers, Mrk Alley, Gyanu Lamichhane
Efficacy of epetraborole against Mycobacteroides abscessus in a mouse model of lung infection. Antimicrobial agents and chemotherapy 68 (8) (2024)
Xin Gu, Pingyu Zhou
Reply to Sumiyoshi, "Concerns about the interpretation of treatment effects". Antimicrobial agents and chemotherapy 68 (8) (2024)
Sanne van der Niet, Keith D Green, Irene M Schimmel, Jordy de Bakker, Bastiaan Lodder, Eric A Reits, Sylvie Garneau-Tsodikova, Nicole N van der Wel
Zafirlukast induces DNA condensation and has bactericidal effect on replicating Mycobacterium abscessus . Antimicrobial agents and chemotherapy 68 (8) (2024)
Barbara Ghiglione, María Margarita Rodríguez, Pedro Penzotti, Christopher R Bethel, Gabriel Gutkind, Robert A Bonomo, Sebastián Klinke, Pablo Power
Crystal structure of the class A extended-spectrum β-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution. Antimicrobial agents and chemotherapy 68 (8) (2024)
Jing Zhou, Hong Zhang, Hong Chen, George Zhang, John Mao, Tianxiang Zhang, Yanan Tang, Wenhao Yan, Chuanjing Li, Yanhua Ding, Qinglong Jin
Pharmacokinetics and safety of GST-HG171, a novel 3CL protease inhibitor, in Chinese subjects with impaired and normal liver function. Antimicrobial agents and chemotherapy 68 (8) (2024)
Barbara Ghiglione, María Margarita Rodríguez, Pedro Penzotti, Christopher R Bethel, Gabriel Gutkind, Robert A Bonomo, Sebastián Klinke, Pablo Power
Crystal structure of the class A extended-spectrum β-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution. Antimicrobial agents and chemotherapy 68 (8) (2024)
Jing Zhou, Hong Zhang, Hong Chen, George Zhang, John Mao, Tianxiang Zhang, Yanan Tang, Wenhao Yan, Chuanjing Li, Yanhua Ding, Qinglong Jin
Pharmacokinetics and safety of GST-HG171, a novel 3CL protease inhibitor, in Chinese subjects with impaired and normal liver function. Antimicrobial agents and chemotherapy 68 (8) (2024)
Stephanie L Egge, Samie A Rizvi, Shelby R Simar, Manuel Alcalde, Jose R W Martinez, Blake M Hanson, An Q Dinh, Rodrigo P Baptista, Truc T Tran, Samuel A Shelburne Iii, Jose M Munita, César A Arias, Morgan Hakki, William R Miller
Cefiderocol heteroresistance associated with mutations in TonB-dependent receptor genes in Pseudomonas aeruginosa of clinical origin. Antimicrobial agents and chemotherapy 68 (8) (2024)
Ellen Van Gulck, Marion Pardons, Erik Nijs, Nick Verheyen, Koen Dockx, Christel Van Den Eynde, Emilie Battivelli, Jerel Vega, Eric Florence, Brigitte Autran, Nancie M Archin, David M Margolis, Christine Katlama, Chiraz Hamimi, Ilse Van Den Wyngaert, Filmon Eyassu, Linos Vandekerckhove, Daniel Boden
Correction for Van Gulck et al., "A truncated HIV Tat demonstrates potent and specific latency reversal activity". Antimicrobial agents and chemotherapy 68 (8) (2024)
Yanqiang Huang, Xudong Hang, Xueqing Jiang, Liping Zeng, Jia Jia, Yong Xie, Fei Li, Hong-Kai Bi
Correction for Huang et al., " In Vitro and In Vivo Activities of Zinc Linolenate, a Selective Antibacterial Agent against Helicobacter pylori ". Antimicrobial agents and chemotherapy 68 (8) (2024)
Mads Lindholm Kurtzhals, Anders Norman, Erik Svensson, Troels Lillebaek, Dorte Bek Folkvardsen
Applying whole genome sequencing to predict phenotypic drug resistance in Mycobacterium tuberculosis : leveraging 20 years of nationwide data from Denmark. Antimicrobial agents and chemotherapy 68 (8) (2024)