Ken Yamada

Publication Activity (10 Years)

Years Active: 2022-2024
Publications (10 Years): 19

Top Topics

Genome Wide Analysis

Top Venues

bioRxiv : the preprint server for biology

Nucleic acids research

Nature biotechnology

This page only lists publications with an associated author ORCID identifier.

Publications

Alexandra Weiss, James W Gilbert, Iris Valeria Rivera Flores, Jillian Belgrad, Chantal M Ferguson, Elif O Dogan, Nicholas Wightman, Kit Mocarski, Dimas Echeverria Moreno, Ashley Summers, Brianna Bramato, Nicholas McHugh, Raymond Furgal, Nozomi Yamada, David Cooper, Kathryn R Monopoli, Bruno M D C Godinho, Matthew R Hassler, Ken Yamada, Paul Greer, Nils Henninger, Robert H Brown, Anastasia Khvorova
RNAi-mediated silencing of SOD1 profoundly extends survival and functional outcomes in ALS mice. bioRxiv : the preprint server for biology (2024)
Ken Yamada, Vignesh Narayan Hariharan, Jillian Caiazzi, Rachael Miller, Chantal M Ferguson, Ellen Sapp, Hassan H Fakih, Qi Tang, Nozomi Yamada, Raymond C Furgal, Joseph D Paquette, Annabelle Biscans, Brianna M Bramato, Nicholas McHugh, Ashley Summers, Clemens Lochmann, Bruno M D C Godinho, Samuel Hildebrand, Samuel O Jackson, Dimas Echeverria, Matthew R Hassler, Julia F Alterman, Marian DiFiglia, Neil Aronin, Anastasia Khvorova
Enhancing siRNA efficacy in vivo with extended nucleic acid backbones. Nature biotechnology (2024)
Jillian Belgrad, Qi Tang, Samuel R Hildebrand, Ashley Summers, Ellen Sapp, Dimas Echeverria Moreno, Daniel O'Reilly, Eric Luu, Brianna Bramato, Sarah Allen, David Cooper, Julia F Alterman, Ken Yamada, Neil Aronin, Marian DiFiglia, Anastasia Khvorova
A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system. Nucleic acids research 52 (11) (2024)
Jillian Belgrad, Qi Tang, Samuel R Hildebrand, Ashley Summers, Ellen Sapp, Dimas Echeverria Moreno, Daniel O'Reilly, Eric Luu, Brianna Bramato, Sarah Allen, David Cooper, Julia F Alterman, Ken Yamada, Neil Aronin, Marian DiFiglia, Anastasia Khvorova
A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system. Nucleic acids research (2024)
Jillian Belgrad, Qi Tang, Samuel R Hildebrand, Ashley Summers, Ellen Sapp, Dimas Echeverria Moreno, Daniel O'Reilly, Eric Luu, Brianna Bramato, Sarah Allen, David Cooper, Julia F Alterman, Ken Yamada, Neil Aronin, Marian DiFiglia, Anastasia Khvorova
A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system. Nucleic acids research 52 (11) (2024)
Sarah Allen, Daniel O'Reilly, Rachael Miller, Ellen Sapp, Ashley Summers, Joseph Paquette, Dimas Echeverria Moreno, Brianna Bramato, Nicholas McHugh, Ken Yamada, Neil Aronin, Marian DiFiglia, Anastasia Khvorova
mRNA nuclear clustering leads to a difference in mutant huntingtin mRNA and protein silencing by siRNAs in vivo . bioRxiv : the preprint server for biology (2024)
Jillian Belgrad, Qi Tang, Samuel R Hildebrand, Ashley Summers, Ellen Sapp, Dimas Echeverria Moreno, Daniel O'Reilly, Eric Luu, Brianna Bramato, Sarah Allen, David Cooper, Julia F Alterman, Ken Yamada, Neil Aronin, Marian DiFiglia, Anastasia Khvorova
A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system. Nucleic acids research 52 (11) (2024)
Jillian Belgrad, Qi Tang, Samuel R Hildebrand, Ashley Summers, Ellen Sapp, Dimas Echeverria Moreno, Daniel O'Reilly, Eric Luu, Brianna Bramato, Sarah Allen, David Cooper, Julia F Alterman, Ken Yamada, Neil Aronin, Marian DiFiglia, Anastasia Khvorova
A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system. Nucleic acids research (2024)
Ken Yamada, Vignesh Narayan Hariharan, Jillian Caiazzi, Rachael Miller, Chantal M Ferguson, Ellen Sapp, Hassan H Fakih, Qi Tang, Nozomi Yamada, Raymond C Furgal, Joseph D Paquette, Annabelle Biscans, Brianna M Bramato, Nicholas McHugh, Ashley Summers, Clemens Lochmann, Bruno M D C Godinho, Samuel Hildebrand, Samuel O Jackson, Dimas Echeverria, Matthew R Hassler, Julia F Alterman, Marian DiFiglia, Neil Aronin, Anastasia Khvorova
Enhancing siRNA efficacy in vivo with extended nucleic acid backbones. Nature biotechnology (2024)
Alexandra Weiss, James W Gilbert, Iris Valeria Rivera Flores, Jillian Belgrad, Chantal M Ferguson, Elif O Dogan, Nicholas Wightman, Kit Mocarski, Dimas Echeverria Moreno, Ashley Summers, Brianna Bramato, Nicholas McHugh, Raymond Furgal, Nozomi Yamada, David Cooper, Kathryn R Monopoli, Bruno M D C Godinho, Matthew R Hassler, Ken Yamada, Paul L Greer, Nils Henninger, Robert H Brown, Anastasia Khvorova
RNAi-mediated silencing of SOD1 profoundly extends survival and functional outcomes in ALS mice. bioRxiv : the preprint server for biology (2024)
Sarah Allen, Daniel O'Reilly, Rachael Miller, Ellen Sapp, Ashley Summers, Joseph Paquette, Dimas Echeverria Moreno, Brianna Bramato, Nicholas McHugh, Ken Yamada, Neil Aronin, Marian DiFiglia, Anastasia Khvorova
mRNA nuclear clustering leads to a difference in mutant huntingtin mRNA and protein silencing by siRNAs in vivo . bioRxiv : the preprint server for biology (2024)
Jillian Belgrad, Qi Tang, Samuel R Hildebrand, Ashley Summers, Ellen Sapp, Dimas Echeverria Moreno, Daniel O'Reilly, Eric Luu, Brianna Bramato, Sarah Allen, David Cooper, Julia F Alterman, Ken Yamada, Neil Aronin, Marian DiFiglia, Anastasia Khvorova
A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system. Nucleic acids research (2024)
Sarah Allen, Daniel O'Reilly, Rachael Miller, Ellen Sapp, Ashley Summers, Joseph Paquette, Dimas Echeverria Moreno, Brianna Bramato, Nicholas McHugh, Ken Yamada, Neil Aronin, Marian DiFiglia, Anastasia Khvorova
mRNA nuclear clustering leads to a difference in mutant huntingtin mRNA and protein silencing by siRNAs in vivo . bioRxiv : the preprint server for biology (2024)
Alexandra Weiss, James W Gilbert, Iris Valeria Rivera Flores, Jillian Belgrad, Chantal M Ferguson, Elif O Dogan, Nicholas Wightman, Kit Mocarski, Dimas Echeverria Moreno, Ashley Summers, Brianna Bramato, Nicholas McHugh, Raymond Furgal, Nozomi Yamada, David Cooper, Kathryn R Monopoli, Bruno M D C Godinho, Matthew R Hassler, Ken Yamada, Paul L Greer, Nils Henninger, Robert H Brown, Anastasia Khvorova
RNAi-mediated silencing of SOD1 profoundly extends survival and functional outcomes in ALS mice. bioRxiv : the preprint server for biology (2024)
Rachael Miller, Joseph Paquette, Alexandra Barker, Ellen Sapp, Nicholas McHugh, Brianna Bramato, Nozomi Yamada, Julia F Alterman, Dimas Echeveria, Ken Yamada, Jonathan K Watts, Christelle Anaclet, Marian DiFiglia, Anastasia Khvorova, Neil Aronin
Preventing acute neurotoxicity of CNS therapeutic oligonucleotides with the addition of Ca 2+ and Mg 2+ in the formulation. bioRxiv : the preprint server for biology (2024)
Sarah Allen, Daniel O'Reilly, Rachael Miller, Ellen Sapp, Ashley Summers, Joseph Paquette, Dimas Echeverria Moreno, Brianna Bramato, Nicholas McHugh, Ken Yamada, Neil Aronin, Marian DiFiglia, Anastasia Khvorova
mRNA nuclear clustering leads to a difference in mutant huntingtin mRNA and protein silencing by siRNAs in vivo . bioRxiv : the preprint server for biology (2024)
Sarah Allen, Daniel O'Reilly, Rachael Miller, Ellen Sapp, Ashley Summers, Joseph Paquette, Dimas Echeverria Moreno, Brianna Bramato, Nicholas McHugh, Ken Yamada, Neil Aronin, Marian DiFiglia, Anastasia Khvorova
mRNA nuclear clustering leads to a difference in mutant huntingtin mRNA and protein silencing by siRNAs in vivo . bioRxiv : the preprint server for biology (2024)
Rachael Miller, Joseph Paquette, Alexandra Barker, Ellen Sapp, Nicholas McHugh, Brianna Bramato, Nazomi Yamada, Julia F Alterman, Dimas Echeveria, Ken Yamada, Jonathan K Watts, Christelle Anaclet, Marian DiFiglia, Anastasia Khvorova, Neil Aronin
Preventing acute neurotoxicity of CNS therapeutic oligonucleotides with the addition of Ca2+ and Mg2+ in the formulation. bioRxiv : the preprint server for biology (2024)
Ken Yamada, Samuel R Hildebrand, Sarah M Davis, Rachael Miller, Faith Conroy, Ellen Sapp, Jillian Caiazzi, Julia F Alterman, Loïc Roux, Dimas Echeverria Moreno, Matthew R Hassler, Edith L Pfister, Marian DiFiglia, Neil Aronin, Anastasia Khvorova
Structurally constrained phosphonate internucleotide linkage impacts oligonucleotide-enzyme interaction, and modulates siRNA activity and allele specificity. Nucleic acids research 49 (21) (2022)