Machteld Nelly Hylkema (Machteld Hylkema, Machteld N Hylkema, M N Hylkema)

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 15

Top Topics

Chronic Obstructive Pulmonary Disease

Top Venues

American journal of physiology. Lung cellular and molecular physiology

Scientific reports

Journal of applied toxicology : JAT

This page only lists publications with an associated author ORCID identifier.

Publications

Dan-Dan Wu, Andy T Y Lau, Yan-Ming Xu, Marjan Reinders-Luinge, Mihaly Koncz, Antal Kiss, Wim Timens, Marianne G Rots, Machteld Nelly Hylkema
Targeted epigenetic silencing of UCHL1 expression suppresses collagen-1 production in human lung epithelial cells. Epigenetics 18 (1) (2023)
Hataitip Tasena, Hidde J Haisma, Maarten van den Berge, Joy van Broekhuizen, Brian K Kennedy, Machteld Nelly Hylkema, Corry-Anke Brandsma, Irene H Heijink
MicroRNAs Associated with Chronic Mucus Hypersecretion in COPD Are Involved in Fibroblast-Epithelium Crosstalk. Cells 11 (3) (2022)
Francisco Drusso Martinez-Garcia, Roderick Harold Jan de Hilster, Prashant Kumar Sharma, Theo Borghuis, Machteld Nelly Hylkema, Janette Kay Burgess, Martim Conrad Harmsen
Architecture and Composition Dictate Viscoelastic Properties of Organ-Derived Extracellular Matrix Hydrogels. Polymers 13 (18) (2021)
Zhijun Zeng, Karolin F Meyer, Khosbayar Lkhagvadorj, Wierd Kooistra, Marjan Reinders-Luinge, Xijin Xu, Xia Huo, Juan Song, Torsten Plösch, Machteld Nelly Hylkema
Prenatal smoke effect on mouse offspring Igf1 promoter methylation from fetal stage to adulthood is organ and sex specific. American journal of physiology. Lung cellular and molecular physiology 318 (3) (2020)
Khosbayar Lkhagvadorj, Zhijun Zeng, Juan Song, Marjan Reinders-Luinge, Wierd Kooistra, Shanshan Song, Susanne Krauss-Etschmann, Barbro N Melgert, Junjun Cao, Machteld Nelly Hylkema
Prenatal smoke exposure dysregulates lung epithelial cell differentiation in mouse offspring: role for AREG-induced EGFR signaling. American journal of physiology. Lung cellular and molecular physiology 319 (4) (2020)
Khosbayar Lkhagvadorj, Zhijun Zeng, Karolin F Meyer, Laura P Verweij, Wierd Kooistra, Marjan Reinders-Luinge, Henk W Dijkhuizen, Inge A M de Graaf, Torsten Plösch, Machteld Nelly Hylkema
Postnatal Smoke Exposure Further Increases the Hepatic Nicotine Metabolism in Prenatally Smoke Exposed Male Offspring and Is Linked with Aberrant Cyp2a5 Methylation. International journal of molecular sciences 22 (1) (2020)
Dan-Dan Wu, Yan-Ming Xu, De-Ju Chen, Zhan-Ling Liang, Xu-Li Chen, Machteld Nelly Hylkema, Marianne G Rots, Sheng-Qing Li, Andy T Y Lau
Ubiquitin carboxyl-terminal hydrolase isozyme L1/UCHL1 suppresses epithelial-mesenchymal transition and is under-expressed in cadmium-transformed human bronchial epithelial cells. Cell biology and toxicology 37 (4) (2020)
Khosbayar Lkhagvadorj, Karolin F Meyer, Laura P Verweij, Wierd Kooistra, Marjan Reinders-Luinge, Henk W Dijkhuizen, Inge A M de Graaf, Torsten Plösch, Machteld Nelly Hylkema
Prenatal smoke exposure induces persistent Cyp2a5 methylation and increases nicotine metabolism in the liver of neonatal and adult male offspring. Epigenetics 15 (12) (2020)
Roderick Harold Jan de Hilster, P K Sharma, M R Jonker, E S White, E A Gercama, M Roobeek, W Timens, M C Harmsen, Machteld Nelly Hylkema, Janette Kay Burgess
Human lung extracellular matrix hydrogels resemble the stiffness and viscoelasticity of native lung tissue. American journal of physiology. Lung cellular and molecular physiology 318 (4) (2020)
Stefan Dehmel, Petra Nathan, Sabine Bartel, Natalia El-Merhie, Hagen Scherb, Katrin Milger, Gerrit John-Schuster, Ali Oender Yildirim, Machteld Nelly Hylkema, Martin Irmler, Johannes Beckers, Bianca Schaub, Oliver Eickelberg, Susanne Krauss-Etschmann
Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner. Scientific reports 8 (1) (2018)
Christina Draijer, Patricia Robbe, Carian E Boorsma, Machteld Nelly Hylkema, Barbro N Melgert
Dual role of YM1+ M2 macrophages in allergic lung inflammation. Scientific reports 8 (1) (2018)
Karolin F Meyer, Rikst Nynke Verkaik-Schakel, Wim Timens, Lester Kobzik, Torsten Plösch, Machteld Nelly Hylkema
The fetal programming effect of prenatal smoking on Igf1r and Igf1 methylation is organ- and sex-specific. Epigenetics 12 (12) (2018)
Zhan-Ling Liang, Dan-Dan Wu, Yue Yao, Fei-Yuan Yu, Lei Yang, Heng Wee Tan, Machteld Nelly Hylkema, Marianne G Rots, Yan-Ming Xu, Andy T Y Lau
Epiproteome profiling of cadmium-transformed human bronchial epithelial cells by quantitative histone post-translational modification-enzyme-linked immunosorbent assay. Journal of applied toxicology : JAT 38 (6) (2018)
K F Meyer, S Krauss-Etschmann, W Kooistra, M Reinders-Luinge, W Timens, L Kobzik, T Plösch, Machteld Nelly Hylkema
Prenatal exposure to tobacco smoke sex dependently influences methylation and mRNA levels of the Igf axis in lungs of mouse offspring. American journal of physiology. Lung cellular and molecular physiology 312 (4) (2017)
Juan Song, David Cano-Rodriquez, Melanie Winkle, Rutger A F Gjaltema, Désirée Goubert, Tomasz P Jurkowski, Irene H Heijink, Marianne G Rots, Machteld Nelly Hylkema
Targeted epigenetic editing of SPDEF reduces mucus production in lung epithelial cells. American journal of physiology. Lung cellular and molecular physiology 312 (3) (2016)