Journal of applied toxicology : JAT

Keyphrases

Publications

volume 44, number 6, 2024

Weiwei Li, Zhonghou Han, Xiurong Yin, Rongjuan Zhou, Hongfeng Liu
CDX2 alleviates hypoxia-induced apoptosis and oxidative stress in spermatogenic cells through suppression of reactive oxygen species-mediated Wnt/β-catenin pathway. Journal of applied toxicology : JAT 44 (6) (2024)
Xianli Meng, Shuhui Xie, Jing Liu, Bingxuan Lv, Xin Huang, Qiang Liu, Xia Wang, Anna Malashicheva, Liu Ju
Low dose cadmium inhibits syndecan-4 expression in glycocalyx of glomerular endothelial cells. Journal of applied toxicology : JAT 44 (6) (2024)

volume 44, number 7, 2024

Jingyi Jin, Xiaoqing Xu, Fengling Li, Fengyi Weng, Bin Zou, Yue Li, Jing Zhao, Shuang Zhang, Dongming Yan, Furong Qiu
Physiologically based pharmacokinetic modeling for confirming the role of CYP3A1/2 and P-glycoprotein in detoxification mechanism between glycyrrhizic acid and aconitine in rats. Journal of applied toxicology : JAT 44 (7) (2024)
Yuanyuan Xiao, Ruxia Liu, Xiaoyue Zhang, Yaofeng Li, Fang Peng, Wenchao Tang
Analysis of cantharidin-induced kidney injury and the protective mechanism of resveratrol in mice determined by liquid chromatography/mass spectrometry-based metabonomics. Journal of applied toxicology : JAT 44 (7) (2024)
Shehnaz Islam, Olivia Sarkar, Sunanda Mukherjee, Sreejata Kamila, Arpan Dey Bhowmik, Ansuman Chattopadhyay
Chronic low-dose chromium VI exposure induces oxidative stress and apoptosis with altered expressions of DNA repair genes and promoter hypermethylation in the liver of Swiss albino mice. Journal of applied toxicology : JAT 44 (7) (2024)
Hui Chen, Xirong Lu, Beiqi Xu, Gang Cheng, Yuyi Li, Dan Xie
Saikosaponin d protects pancreatic acinar cells against cerulein-induced pyroptosis through alleviating mitochondrial damage and inhibiting cGAS-STING pathway. Journal of applied toxicology : JAT 44 (7) (2024)
Yini Zhou, Chao Ning, Yijun Tan, Yaqi Li, Jiaxu Wang, Yuanyuan Shu, Songping Liang, Zhonghua Liu, Ying Wang
ToxMPNN: A deep learning model for small molecule toxicity prediction. Journal of applied toxicology : JAT 44 (7) (2024)
Qingquan Guo, Qiuru Li, Wenyao Liang, Yudong Zhang, Chenyang Jiang, Yihan Zhang, Jianhua Tan, Haishan Zhao
Asiatic acid and madecassic acid cause cardiotoxicity via inflammation and production of excessive reactive oxygen species in zebrafish. Journal of applied toxicology : JAT 44 (7) (2024)
Changda Gong, Yanjun Feng, Jieyu Zhu, Guixia Liu, Yun Tang, Wei-Hua Li
Evaluation of machine learning models for cytochrome P450 3A4, 2D6, and 2C9 inhibition. Journal of applied toxicology : JAT 44 (7) (2024)
Changda Gong, Yanjun Feng, Jieyu Zhu, Guixia Liu, Yun Tang, Wei-Hua Li
Evaluation of machine learning models for cytochrome P450 3A4, 2D6, and 2C9 inhibition. Journal of applied toxicology : JAT 44 (7) (2024)
Sebastien Gregoire, Anne Moustié, Guillaume Lereaux, Laurène Roussel-Berlier, Nicola Jane Hewitt
Use of in vitro ADME methods to identify suitable analogs of homosalate and octisalate for use in a read-across safety assessment. Journal of applied toxicology : JAT 44 (7) (2024)
Yini Zhou, Chao Ning, Yijun Tan, Yaqi Li, Jiaxu Wang, Yuanyuan Shu, Songping Liang, Zhonghua Liu, Ying Wang
ToxMPNN: A deep learning model for small molecule toxicity prediction. Journal of applied toxicology : JAT 44 (7) (2024)
Sigmund J Degitz, Philip P Degoey, Jonathan T Haselman, Jennifer H Olker, Emma H Stacy, Chad Blanksma, Scott Meyer, Kali Z Mattingly, Brett Blackwell, Anne S Opseth, Michael W Hornung
Evaluating potential developmental toxicity of perfluoroalkyl and polyfluoroalkyl substances in Xenopus laevis embryos and larvae. Journal of applied toxicology : JAT 44 (7) (2024)
Changda Gong, Yanjun Feng, Jieyu Zhu, Guixia Liu, Yun Tang, Wei-Hua Li
Evaluation of machine learning models for cytochrome P450 3A4, 2D6, and 2C9 inhibition. Journal of applied toxicology : JAT 44 (7) (2024)
Sebastien Gregoire, Anne Moustié, Guillaume Lereaux, Laurène Roussel-Berlier, Nicola Jane Hewitt
Use of in vitro ADME methods to identify suitable analogs of homosalate and octisalate for use in a read-across safety assessment. Journal of applied toxicology : JAT 44 (7) (2024)
Sigmund J Degitz, Philip P Degoey, Jonathan T Haselman, Jennifer H Olker, Emma H Stacy, Chad Blanksma, Scott Meyer, Kali Z Mattingly, Brett Blackwell, Anne S Opseth, Michael W Hornung
Evaluating potential developmental toxicity of perfluoroalkyl and polyfluoroalkyl substances in Xenopus laevis embryos and larvae. Journal of applied toxicology : JAT 44 (7) (2024)
Hirotoshi Akane, Takeshi Toyoda, Kohei Matsushita, Tomomi Morikawa, Tadashi Kosaka, Hitoshi Tajima, Hiroaki Aoyama, Kumiko Ogawa
Comparison of the sensitivity of histopathological and immunohistochemical analyses and blood hormone levels for early detection of antithyroid effects in rats treated with thyroid peroxidase inhibitors. Journal of applied toxicology : JAT 44 (7) (2024)
Qingquan Guo, Qiuru Li, Wenyao Liang, Yudong Zhang, Chenyang Jiang, Yihan Zhang, Jianhua Tan, Haishan Zhao
Asiatic acid and madecassic acid cause cardiotoxicity via inflammation and production of excessive reactive oxygen species in zebrafish. Journal of applied toxicology : JAT 44 (7) (2024)
Hirotoshi Akane, Takeshi Toyoda, Kohei Matsushita, Tomomi Morikawa, Tadashi Kosaka, Hitoshi Tajima, Hiroaki Aoyama, Kumiko Ogawa
Comparison of the sensitivity of histopathological and immunohistochemical analyses and blood hormone levels for early detection of antithyroid effects in rats treated with thyroid peroxidase inhibitors. Journal of applied toxicology : JAT 44 (7) (2024)
Logan Germain, Louise M Winn
The flame retardant triphenyl phosphate alters the epigenome of embryonic cells in an aquatic in vitro model. Journal of applied toxicology : JAT 44 (7) (2024)
Logan Germain, Louise M Winn
The flame retardant triphenyl phosphate alters the epigenome of embryonic cells in an aquatic in vitro model. Journal of applied toxicology : JAT 44 (7) (2024)

volume 44, number 8, 2024

Zhi Huang, Mo Lin, Lei Wang, Liangding Dou, Xin Hou, Jinwen Zhang, Yongchao Huang, Lifang Wei, Ran An, Dai Wang, Youliang Yao, Dongbei Guo, Zhibo Li, Yongxing Zhang
Bafi A1 inhibits nano-copper oxide-induced mitochondrial damage by reducing the release of copper from lysosomes. Journal of applied toxicology : JAT 44 (8) (2024)
Pracheta Janmeda, Divya Jain, Priya Chaudhary, Mukesh Meena, Devendra Singh
A systematic review on multipotent carcinogenic agent, N-nitrosodiethylamine (NDEA), its major risk assessment, and precautions. Journal of applied toxicology : JAT 44 (8) (2024)
Oskari J Uski, Gregory D Rankin, Håkan Wingfors, Roger Magnusson, Christoffer Boman, Ala Muala, Anders Blomberg, Jenny Bosson, Thomas Sandström
In vitro toxicity evaluation in A549 cells of diesel particulate matter from two different particle sampling systems and several resuspension media. Journal of applied toxicology : JAT 44 (8) (2024)
Xin-Yan Liu, Bo Chen, Rui Zhang, Miao-Qing Zhang, Yuan-Yuan Ma, Ying Han, Jian-Dong Jiang, Jing-Pu Zhang
Atorvastatin-induced intracerebral hemorrhage is inhibited by berberine in zebrafish. Journal of applied toxicology : JAT 44 (8) (2024)
Abdullah Al Sultan, Zahra Rattray, Nicholas J W Rattray
Cytotoxicity and toxicoproteomics analysis of thiazolidinedione exposure in human-derived cardiomyocytes. Journal of applied toxicology : JAT 44 (8) (2024)
Douglas J Fort, Brittanie F Peake, Michael B Mathis, M Annegaaike Leopold, Jeffrey C Wolf, Peter J J M Weterings
Comparing the effects and potencies of perchlorate and nitrate on amphibian metamorphosis using a modified amphibian metamorphosis assay (AMA). Journal of applied toxicology : JAT 44 (8) (2024)
Ji-Eun Park, Soo Min Ko, Hyo-Jeong Han, Ji-Young Lee, Da Som Jeong, Dong Hyun Lee, In Kyung Heo, Yong Uk Shin, Yang Hee Kim, Woo-Chan Son
Toxicology and safety study of L-tryptophan and its impurities for use in swine. Journal of applied toxicology : JAT 44 (8) (2024)
Laíza Moura Almeida-Terassi, Ana Paula Martins Castanha, Greice Rafaele Alves, Valdir Cechinel-Filho, Rivaldo Niero, Isabel O'Neill de Mascarenhas Gaivão, Liana Martins de Oliveira, Luan Vitor Alves de Lima, Mario Sergio Mantovani, Edson Luis Maistro
Cytogenotoxic screening of the natural compound niga-ichigoside F1 from Rubus imperialis (Rosaceae). Journal of applied toxicology : JAT 44 (8) (2024)
Pracheta Janmeda, Divya Jain, Priya Chaudhary, Mukesh Meena, Devendra Singh
A systematic review on multipotent carcinogenic agent, N-nitrosodiethylamine (NDEA), its major risk assessment, and precautions. Journal of applied toxicology : JAT 44 (8) (2024)
Xuan Ni, Chen Gao, Xiaolin Zhu, Xiaosong Zhang, Yizhuo Fang, Zhihui Hao
Isobavachalcone induces hepatotoxicity in zebrafish embryos and HepG2 cells via the System Xc - -GSH-GPX4 signaling pathway in ferroptosis response. Journal of applied toxicology : JAT 44 (8) (2024)
Yitong Liu, Michael Lawless, Miao Li, Kiara Fairman, Michelle R Embry, Constance A Mitchell
Prediction of physicochemical and pharmacokinetic properties of botanical constituents by computational models. Journal of applied toxicology : JAT 44 (8) (2024)
Vanessa Almonti, Stefania Vernazza, Serena Mirata, Sara Tirendi, Mario Passalacqua, Alessandro Francesco Gualtieri, Dario Di Giuseppe, Sonia Scarfi, Anna Maria Bassi
Toxicity and inflammatory potential of mineral fibres: The contribute of released soluble metals versus cell contact direct effects. Journal of applied toxicology : JAT 44 (8) (2024)
Ying Li, Yan Sun, Jianghong Wang, Xiaolong Wang, Wenjie Yang
Voacangine protects hippocampal neuronal cells against oxygen-glucose deprivation/reoxygenation-caused oxidative stress and ferroptosis by activating the PI3K-Akt-FoxO signaling. Journal of applied toxicology : JAT 44 (8) (2024)

volume 44, number 9, 2024

Hongxia Lu, Xulei Zuo, Jiayu Yuan, Zhuoying Xie, Lihong Yin, Yuepu Pu, Zaozao Chen, Juan Zhang
Research progress in the development of 3D skin models and their application to in vitro skin irritation testing. Journal of applied toxicology : JAT 44 (9) (2024)
Xiaodong Liu, Tianyi Jiang, Huiyun Jin, Chenxi Yan, Yuqi Tong, Jiaquan Ding, Yaqi Li, Lian Huang, Zhao-Hui Zhang
mtDNA amplifies beryllium sulfate-induced inflammatory responses via the cGAS-STING pathway in 16HBE cells. Journal of applied toxicology : JAT 44 (9) (2024)
Xiaoyan Duan, Wanting Bai, Jiahuan Hu, Jinjin Wu, Huixin Tan, Fenghe Wang, Xuli Lang, Baolian Wang, Jin-Ping Hu
Inhibitory effect of flavonoids on multidrug and toxin extrusion protein 1 function: Implications for food/herb-drug interaction and drug-induced kidney injury. Journal of applied toxicology : JAT 44 (9) (2024)
Acharya Balkrishna, Sandeep Sinha, Kunal Bhattacharya, Anurag Varshney
Twenty-eight days of repeated dose sub-acute toxicological evaluation of polyherbal Ayurvedic medicine BPGrit in Sprague-Dawley rats. Journal of applied toxicology : JAT 44 (9) (2024)
Meenakshi Chandel, Amit Kumar Sharma, Kushal Thakur, Dixit Sharma, Bhavna Brar, Danish Mahajan, Hishani Kumari, Pranay Punj Pankaj, Rakesh Kumar
Poison in the water: Arsenic's silent assault on fish health. Journal of applied toxicology : JAT 44 (9) (2024)
Che-Sheng Chu, Ying-Tso Chen, Wei-Zhe Liang
Investigation of the mechanisms behind ochratoxin A-induced cytotoxicity in human astrocytes and the protective effects of N-acetylcysteine. Journal of applied toxicology : JAT 44 (9) (2024)
Yan Wang, Liping Wei, Yuan Liu, Cheng Liu, Minbo Hou, Lu Zhou, Le Wang, Hua Li, Yunliang Qiu, null JingMa
Biodistribution and preclinical safety profile of legubicin: A novel conjugate of doxorubicin and a legumain-cleavable peptide linker. Journal of applied toxicology : JAT 44 (9) (2024)
Xiugong Gao, Kayla Campasino, Miranda R Yourick, Yu Cao, Jeffrey J Yourick, Robert L Sprando
Oxidative DNA damage contributes to usnic acid-induced toxicity in human induced pluripotent stem cell-derived hepatocytes. Journal of applied toxicology : JAT 44 (9) (2024)
Kelly Yoshizaki, Daniela Perroni Frias, Kevin Maier, Juliana Smelan, Aristides Tadeu Correia, Luanda Mara da Silva Oliveira, Luís Fernando Amato-Lourenço, Bruna Tereso Santillo, Carla Máximo Prado, Telma Miyuki Oshiro, José Alexandre Marzagão Barbuto, Thais Mauad, Mariangela Macchione
Exposure of cinnamyl alcohol in co-culture of BEAS-2B and dendritic cells: Interaction between CYP450 and cytokines. Journal of applied toxicology : JAT 44 (9) (2024)
Katharina Klinzing, Ida Aabrandt Søndergaard, Teresa Chirom, James Whitwell, Laura Bisini, Cristina Marabottini, Fabrice Nesslany, Petri Tervasmäki, Juha-Pekka Pitkänen
In vitro genotoxicological evaluation of protein-rich powder derived from Xanthobacter sp. SoF1. Journal of applied toxicology : JAT 44 (9) (2024)
Xiaoyan Duan, Wanting Bai, Jiahuan Hu, Jinjin Wu, Huixin Tan, Fenghe Wang, Xuli Lang, Baolian Wang, Jin-Ping Hu
Inhibitory effect of flavonoids on multidrug and toxin extrusion protein 1 function: Implications for food/herb-drug interaction and drug-induced kidney injury. Journal of applied toxicology : JAT 44 (9) (2024)
Lina Thors, Elisabeth Wigenstam, Johanna Qvarnström, Pär Wästerby, Linda Öberg, Anders Bucht
Immediate dry decontamination using efficient absorbent materials is beneficial following skin exposure to low-volatile toxic chemicals. Journal of applied toxicology : JAT 44 (9) (2024)
Wenwen Zhuang, Seo-Yeong Mun, Minju Park, Junsu Jeong, Hye Ryung Kim, Hongzoo Park, Eun-Taek Han, Jin-Hee Han, Wanjoo Chun, Hongliang Li, Won Sun Park
Second-generation antipsychotic quetiapine blocks voltage-dependent potassium channels in coronary arterial smooth muscle cells. Journal of applied toxicology : JAT 44 (9) (2024)
Ümit Acar, Burak Evren İnanan, Fahriye Zemheri-Navruz
Ecotoxicological effects of polystyrene nanoplastics on common carp: Insights into blood parameters, DNA damage, and gene expression. Journal of applied toxicology : JAT 44 (9) (2024)
Xiaodong Liu, Tianyi Jiang, Huiyun Jin, Chenxi Yan, Yuqi Tong, Jiaquan Ding, Yaqi Li, Lian Huang, Zhao-Hui Zhang
mtDNA amplifies beryllium sulfate-induced inflammatory responses via the cGAS-STING pathway in 16HBE cells. Journal of applied toxicology : JAT 44 (9) (2024)
Katharina Klinzing, Ida Aabrandt Søndergaard, Teresa Chirom, James Whitwell, Laura Bisini, Cristina Marabottini, Fabrice Nesslany, Petri Tervasmäki, Juha-Pekka Pitkänen
In vitro genotoxicological evaluation of protein-rich powder derived from Xanthobacter sp. SoF1. Journal of applied toxicology : JAT 44 (9) (2024)