Malcolm E Winkler

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 36

Top Topics

Hypertrophic Cardiomyopathy

Binding Protein

Bacillus Subtilis

Top Venues

Journal of bacteriology

Molecular microbiology

bioRxiv : the preprint server for biology

Proceedings of the National Academy of Sciences of the United States of America

This page only lists publications with an associated author ORCID identifier.

Publications

Amilcar J Perez, Melissa Mae Lamanna, Kevin E Bruce, Marc A Touraev, Julia E Page, Sidney L Shaw, Ho-Ching Tiffany Tsui, Malcolm E Winkler
Elongasome core proteins and class A PBP1a display zonal, processive movement at the midcell of Streptococcus pneumoniae . Proceedings of the National Academy of Sciences of the United States of America 121 (25) (2024)
Amilcar J Perez, Melissa Mae Lamanna, Kevin E Bruce, Marc A Touraev, Julia E Page, Sidney L Shaw, Ho-Ching Tiffany Tsui, Malcolm E Winkler
Elongasome core proteins and class A PBP1a display zonal, processive movement at the midcell of Streptococcus pneumoniae . Proceedings of the National Academy of Sciences of the United States of America 121 (25) (2024)
Amilcar J Perez, Melissa Mae Lamanna, Kevin E Bruce, Marc A Touraev, Julia E Page, Sidney L Shaw, Ho-Ching Tiffany Tsui, Malcolm E Winkler
Elongasome core proteins and class A PBP1a display zonal, processive movement at the midcell of Streptococcus pneumoniae . bioRxiv : the preprint server for biology (2024)
Marshall Jaroch, Guangxin Sun, Ho-Ching Tiffany Tsui, Colbie Reed, Jingjing Sun, Marko Jörg, Malcolm E Winkler, Kelly C Rice, Agnieszka Dziergowska, Troy A Stich, Peter C Dedon, Patricia C Dos Santos, Valérie de Crécy-Lagard
Alternate routes to mnm 5 s 2 U synthesis in Gram-positive bacteria. Journal of bacteriology (2024)
Amilcar J Perez, Melissa Mae Lamanna, Kevin E Bruce, Marc A Touraev, Julia E Page, Sidney L Shaw, Ho-Ching Tiffany Tsui, Malcolm E Winkler
Elongasome core proteins and class A PBP1a display zonal, processive movement at the midcell of Streptococcus pneumoniae . Proceedings of the National Academy of Sciences of the United States of America 121 (25) (2024)
Amilcar J Perez, Melissa Mae Lamanna, Kevin E Bruce, Marc A Touraev, Julia E Page, Sidney L Shaw, Ho-Ching Tiffany Tsui, Malcolm E Winkler
Elongasome core proteins and class A PBP1a display zonal, processive movement at the midcell of Streptococcus pneumoniae . bioRxiv : the preprint server for biology (2024)
Marshall Jaroch, Guangxin Sun, Ho-Ching Tiffany Tsui, Colbie Reed, Jingjing Sun, Marko Jörg, Malcolm E Winkler, Kelly C Rice, Agnieszka Dziergowska, Troy A Stich, Peter C Dedon, Patricia C Dos Santos, Valérie de Crécy-Lagard
Alternate routes to mnm 5 s 2 U synthesis in Gram-positive bacteria. Journal of bacteriology 206 (4) (2024)
Marshall Jaroch, Guangxin Sun, Ho-Ching Tiffany Tsui, Colbie Reed, Jingjing Sun, Marko Jörg, Malcolm E Winkler, Kelly C Rice, Agnieszka Dziergowska, Troy A Stich, Peter C Dedon, Patricia C Dos Santos, Valérie de Crécy-Lagard
Alternate routes to mnm 5 s 2 U synthesis in Gram-positive bacteria. Journal of bacteriology 206 (4) (2024)
Marshall Jaroch, Guangxin Sun, Ho-Ching Tiffany Tsui, Colbie Reed, Jingjing Sun, Marko Jörg, Malcolm E Winkler, Kelly C Rice, Agnieszka Dziergowska, Troy A Stich, Peter C Dedon, Patricia C Dos Santos, Valérie de Crécy-Lagard
Alternate routes to mnm 5 s 2 U synthesis in Gram-positive bacteria. Journal of bacteriology 206 (4) (2024)
Amilcar J Perez, Melissa Mae Lamanna, Kevin E Bruce, Marc A Touraev, Julia E Page, Sidney L Shaw, Ho-Ching Tiffany Tsui, Malcolm E Winkler
Elongasome core proteins and class A PBP1a display zonal, processive movement at the midcell of Streptococcus pneumoniae . Proceedings of the National Academy of Sciences of the United States of America 121 (25) (2024)
Amilcar J Perez, Melissa Mae Lamanna, Kevin E Bruce, Marc A Touraev, Julia E Page, Sidney L Shaw, Ho-Ching Tiffany Tsui, Malcolm E Winkler
Elongasome core proteins and class A PBP1a display zonal, processive movement at the midcell of Streptococcus pneumoniae . bioRxiv : the preprint server for biology (2024)
Amilcar J Perez, Melissa Mae Lamanna, Kevin E Bruce, Marc A Touraev, Julia E Page, Sidney L Shaw, Ho-Ching Tiffany Tsui, Malcolm E Winkler
Elongasome core proteins and class A PBP1a display zonal, processive movement at the midcell of Streptococcus pneumoniae . Proceedings of the National Academy of Sciences of the United States of America 121 (25) (2024)
Marshall Jaroch, Guangxin Sun, Ho-Ching Tiffany Tsui, Colbie Reed, Jingjing Sun, Marko Jörg, Malcolm E Winkler, Kelly C Rice, Agnieszka Dziergowska, Troy A Stich, Peter C Dedon, Patricia C Dos Santos, Valérie de Crécy-Lagard
Alternate routes to mnm 5 s 2 U synthesis in Gram-positive bacteria. Journal of bacteriology 206 (4) (2024)
Marshall Jaroch, Guangxin Sun, Ho-Ching Tiffany Tsui, Colbie Reed, Jingjing Sun, Marko Jörg, Malcolm E Winkler, Kelly C Rice, Agnieszka Dziergowska, Troy A Stich, Peter C Dedon, Patricia C Dos Santos, Valérie de Crécy-Lagard
Alternate routes to mnm 5 s 2 U synthesis in Gram-positive bacteria. Journal of bacteriology (2024)
Mohammad M Rahman, Svetlana Zamakhaeva, Jeffrey S Rush, Catherine T Chaton, Cameron W Kenner, Yin Mon Hla, Ho-Ching Tiffany Tsui, Vladimir N Uversky, Malcolm E Winkler, Konstantin V Korotkov, Natalia Korotkova
O -glycosylation of intrinsically disordered regions regulates homeostasis of membrane proteins in streptococci. bioRxiv : the preprint server for biology (2024)
Marshall Jaroch, Guangxin Sun, Ho-Ching Tiffany Tsui, Colbie Reed, Jingjing Sun, Marko Jörg, Malcolm E Winkler, Kelly C Rice, Agnieszka Dziergowska, Troy A Stich, Peter C Dedon, Patricia C Dos Santos, Valérie de Crécy-Lagard
Alternate routes to mnm 5 s 2 U synthesis in Gram-positive bacteria. Journal of bacteriology 206 (4) (2024)
Mohammad M Rahman, Svetlana Zamakhaeva, Jeffrey S Rush, Catherine T Chaton, Cameron W Kenner, Yin Mon Hla, Ho-Ching Tiffany Tsui, Malcolm E Winkler, Konstantin V Korotkov, Natalia Korotkova
Disorder regulates homeostasis of extracytoplasmic proteins in streptococci. bioRxiv : the preprint server for biology (2024)
Marshall Jaroch, Guangxin Sun, Ho-Ching Tiffany Tsui, Colbie Reed, Jingjing Sun, Marko Jörg, Malcolm E Winkler, Kelly C Rice, Agnieszka Dziergowska, Troy A Stich, Peter C Dedon, Patricia C Dos Santos, Valérie de Crécy-Lagard
Alternate routes to mnm 5 s 2 U synthesis in Gram-positive bacteria. Journal of bacteriology 206 (4) (2024)
Marshall Jaroch, Guangxin Sun, Ho-Ching Tiffany Tsui, Colbie Reed, Jingjing Sun, Marko Jörg, Malcolm E Winkler, Kelly C Rice, Agnieszka Dziergowska, Troy A Stich, Peter C Dedon, Patricia C Dos Santos, Valérie de Crécy-Lagard
Alternate routes to mnm 5 s 2 U synthesis in Gram-positive bacteria. Journal of bacteriology 206 (4) (2024)
Mohammad M Rahman, Svetlana Zamakhaeva, Jeffrey S Rush, Catherine T Chaton, Cameron W Kenner, Yin Mon Hla, Ho-Ching Tiffany Tsui, Vladimir N Uversky, Malcolm E Winkler, Konstantin V Korotkov, Natalia Korotkova
O -glycosylation of intrinsically disordered regions regulates homeostasis of membrane proteins in streptococci. bioRxiv : the preprint server for biology (2024)
Amilcar J Perez, Melissa Mae Lamanna, Kevin E Bruce, Marc A Touraev, Julia E Page, Sidney L Shaw, Ho-Ching Tiffany Tsui, Malcolm E Winkler
Elongasome core proteins and class A PBP1a display zonal, processive movement at the midcell of Streptococcus pneumoniae . bioRxiv : the preprint server for biology (2024)
Malcolm E Winkler, Merrin Joseph, Ho-Ching Tiffany Tsui
Secrets of getting started: Regulation of the first committed step of peptidoglycan synthesis by protein phosphorylation in Enterococcus and other Gram-positive bacteria. Molecular microbiology (2023)
Ho-Ching Tiffany Tsui, Merrin Joseph, Jiaqi J Zheng, Amilcar J Perez, Irfan Manzoor, Britta E Rued, John D Richardson, Pavel Branny, Linda Doubravová, Orietta Massidda, Malcolm E Winkler
Chromosomal Duplications of MurZ (MurA2) or MurA (MurA1), Amino Acid Substitutions in MurZ (MurA2), and Absence of KhpAB Obviate the Requirement for Protein Phosphorylation in Streptococcus pneumoniae D39. bioRxiv : the preprint server for biology (2023)
Ho-Ching Tiffany Tsui, Merrin Joseph, Jiaqi J Zheng, Amilcar J Perez, Irfan Manzoor, Britta E Rued, John D Richardson, Pavel Branny, Linda Doubravová, Orietta Massidda, Malcolm E Winkler
Negative regulation of MurZ and MurA underlies the essentiality of GpsB- and StkP-mediated protein phosphorylation in Streptococcus pneumoniae D39. Molecular microbiology (2023)
Melissa Mae Lamanna, Irfan Manzoor, Merrin Joseph, Ziyun A Ye, Mattia Benedet, Alessia Zanardi, Zhongqing Ren, Xindan Wang, Orietta Massidda, Ho-Ching Tiffany Tsui, Malcolm E Winkler
Roles of RodZ and class A PBP1b in the assembly and regulation of the peripheral peptidoglycan elongasome in ovoid-shaped cells of Streptococcus pneumoniae D39. Molecular microbiology 118 (4) (2022)
Atsushi Taguchi, Julia E Page, Ho-Ching Tiffany Tsui, Malcolm E Winkler, Suzanne Walker
Biochemical reconstitution defines new functions for membrane-bound glycosidases in assembly of the bacterial cell wall. Proceedings of the National Academy of Sciences of the United States of America 118 (36) (2022)
Dhriti Sinha, Jacob P Frick, Kristen Clemons, Malcolm E Winkler, Nicholas R De Lay
Pivotal Roles for Ribonucleases in Streptococcus pneumoniae Pathogenesis. mBio 12 (5) (2021)
Malcolm E Winkler
Undermodification cues division. Nature chemical biology 17 (8) (2021)
Joshua W McCausland, Xinxing Yang, Georgia R Squyres, Zhixin Lyu, Kevin E Bruce, Melissa Mae Lamanna, Bill Söderström, Ethan C Garner, Malcolm E Winkler, Jie Xiao, Jian Liu
Treadmilling FtsZ polymers drive the directional movement of sPG-synthesis enzymes via a Brownian ratchet mechanism. Nature communications 12 (1) (2021)
Amilcar J Perez, Michael J Boersma, Kevin E Bruce, Melissa M Lamanna, Sidney L Shaw, Ho-Ching T Tsui, Atsushi Taguchi, Erin E Carlson, Michael S VanNieuwenhze, Malcolm E Winkler
Organization of peptidoglycan synthesis in nodes and separate rings at different stages of cell division of Streptococcus pneumoniae. Molecular microbiology 115 (6) (2020)
Dhriti Sinha, Jiaqi J Zheng, Ho-Ching Tiffany Tsui, John D Richardson, Nicholas R De Lay, Malcolm E Winkler
S1 Domain RNA-Binding Protein CvfD Is a New Posttranscriptional Regulator That Mediates Cold Sensitivity, Phosphate Transport, and Virulence in Streptococcus pneumoniae D39. Journal of bacteriology 202 (18) (2020)
Robert M Cleverley, Zoe J Rutter, Jeanine Rismondo, Federico Corona, Ho-Ching Tiffany Tsui, Fuad A Alatawi, Richard A Daniel, Sven Halbedel, Orietta Massidda, Malcolm E Winkler, Richard J Lewis
The cell cycle regulator GpsB functions as cytosolic adaptor for multiple cell wall enzymes. Nature communications 10 (1) (2019)
Jiaqi J Zheng, Amilcar J Perez, Ho-Ching Tiffany Tsui, Orietta Massidda, Malcolm E Winkler
Absence of the KhpA and KhpB (JAG/EloR) RNA-binding proteins suppresses the requirement for PBP2b by overproduction of FtsA in Streptococcus pneumoniae D39. Molecular microbiology 106 (5) (2017)
Julia E Martin, Katherine A Edmonds, Kevin E Bruce, Gregory C Campanello, Bart A Eijkelkamp, Erin B Brazel, Christopher A McDevitt, Malcolm E Winkler, David P Giedroc
The zinc efflux activator SczA protects Streptococcus pneumoniae serotype 2 D39 from intracellular zinc toxicity. Molecular microbiology 104 (4) (2017)
Julia E Martin, John P Lisher, Malcolm E Winkler, David P Giedroc
Perturbation of manganese metabolism disrupts cell division in Streptococcus pneumoniae. Molecular microbiology 104 (2) (2017)
Britta E Rued, Jiaqi J Zheng, Andrea Mura, Ho-Ching T Tsui, Michael J Boersma, Jeffrey L Mazny, Federico Corona, Amilcar J Perez, Daniela Fadda, Linda Doubravová, Karolína Buriánková, Pavel Branny, Orietta Massidda, Malcolm E Winkler
Suppression and synthetic-lethal genetic relationships of ΔgpsB mutations indicate that GpsB mediates protein phosphorylation and penicillin-binding protein interactions in Streptococcus pneumoniae D39. Molecular microbiology 103 (6) (2017)