Nature chemical biology

Keyphrases

Publications

volume 20, number 8, 2024

Duo Xu, Joshua J Carter, Chunfeng Li, Ashley Utz, Payton A B Weidenbacher, Shaogeng Tang, Mrinmoy Sanyal, Bali Pulendran, Christopher O Barnes, Peter S Kim
Vaccine design via antigen reorientation. Nature chemical biology 20 (8) (2024)
Matthew W McHenry, Peiwen Shi, Christina M Camara, Daniel T Cohen, T Justin Rettenmaier, Utsarga Adhikary, Micah A Gygi, Ka Yang, Steven P Gygi, Thomas E Wales, John R Engen, James A Wells, Loren D Walensky
Covalent inhibition of pro-apoptotic BAX. Nature chemical biology 20 (8) (2024)
Tzu-Yuan Chiu, Daniel C Lazar, Wesley W Wang, Jacob M Wozniak, Appaso M Jadhav, Weichao Li, Nathalia Gazaniga, Argyrios N Theofilopoulos, John R Teijaro, Christopher G Parker
Chemoproteomic development of SLC15A4 inhibitors with anti-inflammatory activity. Nature chemical biology 20 (8) (2024)
Marija Veličković, Ruonan Wu, Yuqian Gao, Margaret W Thairu, Dušan Veličković, Nathalie Munoz Munoz, Chaevien S Clendinen, Aivett Bilbao, Rosalie K Chu, Priscila M Lalli, Kevin Zemaitis, Carrie D Nicora, Jennifer E Kyle, Daniel J Orton, Sarai Williams, Ying Zhu, Rui Zhao, Matthew E Monroe, Ronald J Moore, Bobbie-Jo M Webb-Robertson, Lisa M Bramer, Cameron R Currie, Paul D Piehowski, Kristin E Burnum-Johnson
Mapping microhabitats of lignocellulose decomposition by a microbial consortium. Nature chemical biology 20 (8) (2024)
Katherine I Albanese, Rokas Petrenas, Fabio Pirro, Elise A Naudin, Ufuk Borucu, William M Dawson, D Arne Scott, Graham J Leggett, Orion David Weiner, Thomas A A Oliver, Derek N Woolfson
Rationally seeded computational protein design of ɑ-helical barrels. Nature chemical biology 20 (8) (2024)

volume 20, number 9, 2024

Qinheng Zheng, Ziyang Zhang, Keelan Z Guiley, Kevan M Shokat
Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D. Nature chemical biology 20 (9) (2024)
Benjamin J Polacco, Braden T Lobingier, Emily E Blythe, Nohely Abreu, Prachi Khare, Matthew K Howard, Alberto J Gonzalez-Hernandez, Jiewei Xu, Qiongyu Li, Brandon Novy, Zun Zar Chi Naing, Brian K Shoichet, Willow Coyote-Maestas, Joshua Levitz, Nevan J Krogan, Mark Von Zastrow, Ruth Hüttenhain
Profiling the proximal proteome of the activated μ-opioid receptor. Nature chemical biology 20 (9) (2024)
Yihui Shen, Hoang V Dinh, Edward R Cruz, Zihong Chen, Caroline R Bartman, Tianxia Xiao, Catherine M Call, Rolf-Peter Ryseck, Jimmy Pratas, Daniel Weilandt, Heide Baron, Arjuna Subramanian, Zia Fatma, Zong-Yen Wu, Sudharsan Dwaraknath, John I Hendry, Vinh G Tran, Lifeng Yang, Yasuo Yoshikuni, Huimin Zhao, Costas D Maranas, Martin Wühr, Joshua D Rabinowitz
Mitochondrial ATP generation is more proteome efficient than glycolysis. Nature chemical biology 20 (9) (2024)
Yihui Shen, Hoang V Dinh, Edward R Cruz, Zihong Chen, Caroline R Bartman, Tianxia Xiao, Catherine M Call, Rolf-Peter Ryseck, Jimmy Pratas, Daniel Weilandt, Heide Baron, Arjuna Subramanian, Zia Fatma, Zong-Yen Wu, Sudharsan Dwaraknath, John I Hendry, Vinh G Tran, Lifeng Yang, Yasuo Yoshikuni, Huimin Zhao, Costas D Maranas, Martin Wühr, Joshua D Rabinowitz
Mitochondrial ATP generation is more proteome efficient than glycolysis. Nature chemical biology 20 (9) (2024)
Jorge Herrero-Vicente, Douglas L Black, Juan Valcárcel
Splice-modifying drug mechanisms. Nature chemical biology 20 (9) (2024)
Xiao-Wang Chen, Zhiyu Bo, Yang Yang
Artificial boron enzymes. Nature chemical biology 20 (9) (2024)
Chris A Brosey, Todd M Link, Runze Shen, Davide Moiani, Kathryn Burnett, Greg L Hura, Darin E Jones, John A Tainer
Chemical screening by time-resolved X-ray scattering to discover allosteric probes. Nature chemical biology 20 (9) (2024)
Lei Yang, Yanan Huo, Man Wang, Dan Zhang, Tianai Zhang, Hao Wu, Xichen Rao, Haowei Meng, Shuming Yin, Jiale Mei, Dexin Zhang, Xi Chen, Jia Lv, Meizhen Liu, Yiyun Cheng, Yuting Guan, Bo Feng, Gaojie Song, Chengqi Yi, Mingyao Liu, Fanyi Zeng, Liren Wang, Dali Li
Engineering APOBEC3A deaminase for highly accurate and efficient base editing. Nature chemical biology 20 (9) (2024)
Russell Johnson
Polymers produced with depolymerase. Nature chemical biology 20 (9) (2024)
Xiao-Wang Chen, Zhiyu Bo, Yang Yang
Artificial boron enzymes. Nature chemical biology 20 (9) (2024)
Benjamin J Polacco, Braden T Lobingier, Emily E Blythe, Nohely Abreu, Prachi Khare, Matthew K Howard, Alberto J Gonzalez-Hernandez, Jiewei Xu, Qiongyu Li, Brandon Novy, Zun Zar Chi Naing, Brian K Shoichet, Willow Coyote-Maestas, Joshua Levitz, Nevan J Krogan, Mark Von Zastrow, Ruth Hüttenhain
Profiling the proximal proteome of the activated μ-opioid receptor. Nature chemical biology 20 (9) (2024)
Dominic D G Owens, Matthew E R Maitland, Aliakbar Khalili Yazdi, Xiaosheng Song, Viviane Reber, Martin Peter Schwalm, Raquel Arminda Carvalho Machado, Nicolas Bauer, Xu Wang, Magdalena M Szewczyk, Cheng Dong, Aiping Dong, Peter Loppnau, Matthew F Calabrese, Matthew S Dowling, Jisun Lee, Justin I Montgomery, Thomas N O'Connell, Chakrapani Subramanyam, Feng Wang, Ella C Adamson, Matthieu Schapira, Matthias Gstaiger, Stefan Knapp, Masoud Vedadi, Jinrong Min, Gilles A Lajoie, Dalia Barsyte-Lovejoy, Dafydd R Owen, Caroline Schild-Poulter, Cheryl H Arrowsmith
A chemical probe to modulate human GID4 Pro/N-degron interactions. Nature chemical biology 20 (9) (2024)
Hai-Tsang Huang, Ryan J Lumpkin, Ryan W Tsai, Shuyao Su, Xu Zhao, Yuan Xiong, James Chen, Nada Mageed, Katherine Aleisha Donovan, Eric S Fischer, William R Sellers
Ubiquitin-specific proximity labeling for the identification of E3 ligase substrates. Nature chemical biology 20 (9) (2024)
Nicholas J Wright, Feng Zhang, Yang Suo, Lingyang Kong, Ying Yin, Justin G Fedor, Kedar Sharma, Mario Juan Borgnia, Wonpil Im, Seok-Yong Lee
Antiviral drug recognition and elevator-type transport motions of CNT3. Nature chemical biology 20 (9) (2024)
Gene Chong
A pathway revisited. Nature chemical biology 20 (9) (2024)
Aaron S Petruzzella, Marine Bruand, Albert Santamaria-Martinez, Natalya Katanayeva, Luc Reymond, Sarah Wehrle, Sandrine Georgeon, Damla Inel, Floris J van Dalen, David Viertl, Kelvin Lau, Florence Pojer, Margret Schottelius, Vincent Zoete, Martijn Verdoes, Caroline Arber, Bruno E Correia, Elisa Oricchio
Antibody-peptide conjugates deliver covalent inhibitors blocking oncogenic cathepsins. Nature chemical biology 20 (9) (2024)
Dominic D G Owens, Matthew E R Maitland, Aliakbar Khalili Yazdi, Xiaosheng Song, Viviane Reber, Martin Peter Schwalm, Raquel Arminda Carvalho Machado, Nicolas Bauer, Xu Wang, Magdalena M Szewczyk, Cheng Dong, Aiping Dong, Peter Loppnau, Matthew F Calabrese, Matthew S Dowling, Jisun Lee, Justin I Montgomery, Thomas N O'Connell, Chakrapani Subramanyam, Feng Wang, Ella C Adamson, Matthieu Schapira, Matthias Gstaiger, Stefan Knapp, Masoud Vedadi, Jinrong Min, Gilles A Lajoie, Dalia Barsyte-Lovejoy, Dafydd R Owen, Caroline Schild-Poulter, Cheryl H Arrowsmith
A chemical probe to modulate human GID4 Pro/N-degron interactions. Nature chemical biology 20 (9) (2024)
Hai-Tsang Huang, Ryan J Lumpkin, Ryan W Tsai, Shuyao Su, Xu Zhao, Yuan Xiong, James Chen, Nada Mageed, Katherine Aleisha Donovan, Eric S Fischer, William R Sellers
Ubiquitin-specific proximity labeling for the identification of E3 ligase substrates. Nature chemical biology 20 (9) (2024)
Kenneth D Westover
Another KRAS variant trapped. Nature chemical biology 20 (9) (2024)
Majda Bratovič
Lipids on the move. Nature chemical biology 20 (9) (2024)
Chris A Brosey, Todd M Link, Runze Shen, Davide Moiani, Kathryn Burnett, Greg L Hura, Darin E Jones, John A Tainer
Chemical screening by time-resolved X-ray scattering to discover allosteric probes. Nature chemical biology 20 (9) (2024)
Max B Sosa, Michelle C Y Chang
Solving the mystery of enediyne biosynthesis. Nature chemical biology 20 (9) (2024)
Nicholas J Wright, Feng Zhang, Yang Suo, Lingyang Kong, Ying Yin, Justin G Fedor, Kedar Sharma, Mario Juan Borgnia, Wonpil Im, Seok-Yong Lee
Antiviral drug recognition and elevator-type transport motions of CNT3. Nature chemical biology 20 (9) (2024)
Aaron S Petruzzella, Marine Bruand, Albert Santamaria-Martinez, Natalya Katanayeva, Luc Reymond, Sarah Wehrle, Sandrine Georgeon, Damla Inel, Floris J van Dalen, David Viertl, Kelvin Lau, Florence Pojer, Margret Schottelius, Vincent Zoete, Martijn Verdoes, Caroline Arber, Bruno E Correia, Elisa Oricchio
Antibody-peptide conjugates deliver covalent inhibitors blocking oncogenic cathepsins. Nature chemical biology 20 (9) (2024)
Chun Gui, Edward Kalkreuter, Lukas Lauterbach, Dong Yang, Ben Shen
Enediyne natural product biosynthesis unified by a diiodotetrayne intermediate. Nature chemical biology 20 (9) (2024)
Chris A Brosey, Todd M Link, Runze Shen, Davide Moiani, Kathryn Burnett, Greg L Hura, Darin E Jones, John A Tainer
Chemical screening by time-resolved X-ray scattering to discover allosteric probes. Nature chemical biology 20 (9) (2024)
Chris A Brosey, Todd M Link, Runze Shen, Davide Moiani, Kathryn Burnett, Greg L Hura, Darin E Jones, John A Tainer
Chemical screening by time-resolved X-ray scattering to discover allosteric probes. Nature chemical biology 20 (9) (2024)
Benjamin J Polacco, Braden T Lobingier, Emily E Blythe, Nohely Abreu, Prachi Khare, Matthew K Howard, Alberto J Gonzalez-Hernandez, Jiewei Xu, Qiongyu Li, Brandon Novy, Zun Zar Chi Naing, Brian K Shoichet, Willow Coyote-Maestas, Joshua Levitz, Nevan J Krogan, Mark Von Zastrow, Ruth Hüttenhain
Profiling the proximal proteome of the activated μ-opioid receptor. Nature chemical biology 20 (9) (2024)
Kenneth D Westover
Another KRAS variant trapped. Nature chemical biology 20 (9) (2024)
Qinheng Zheng, Ziyang Zhang, Keelan Z Guiley, Kevan M Shokat
Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D. Nature chemical biology 20 (9) (2024)
Russell Johnson
Polymers produced with depolymerase. Nature chemical biology 20 (9) (2024)
Majda Bratovič
Lipids on the move. Nature chemical biology 20 (9) (2024)
Nicole A Wenzell, Brian B Tuch, Dustin L McMinn, Matthew J Lyons, Christopher J Kirk, Jack Taunton
Global signal peptide profiling reveals principles of selective Sec61 inhibition. Nature chemical biology 20 (9) (2024)
Gene Chong
A pathway revisited. Nature chemical biology 20 (9) (2024)
Chun Gui, Edward Kalkreuter, Lukas Lauterbach, Dong Yang, Ben Shen
Enediyne natural product biosynthesis unified by a diiodotetrayne intermediate. Nature chemical biology 20 (9) (2024)
Krishna Neupane, Abhishek Narayan, Supratik Sen Mojumdar, Gaurav Adhikari, Craig R Garen, Michael T Woodside
Direct observation of prion-like propagation of protein misfolding templated by pathogenic mutants. Nature chemical biology 20 (9) (2024)
Shaoshuai Xie, Gang Li
A key to unlock ubiquitin ligase function. Nature chemical biology 20 (9) (2024)
Jorge Herrero-Vicente, Douglas L Black, Juan Valcárcel
Splice-modifying drug mechanisms. Nature chemical biology 20 (9) (2024)
Nicole A Wenzell, Brian B Tuch, Dustin L McMinn, Matthew J Lyons, Christopher J Kirk, Jack Taunton
Global signal peptide profiling reveals principles of selective Sec61 inhibition. Nature chemical biology 20 (9) (2024)
Benjamin J Polacco, Braden T Lobingier, Emily E Blythe, Nohely Abreu, Prachi Khare, Matthew K Howard, Alberto J Gonzalez-Hernandez, Jiewei Xu, Qiongyu Li, Brandon Novy, Zun Zar Chi Naing, Brian K Shoichet, Willow Coyote-Maestas, Joshua Levitz, Nevan J Krogan, Mark Von Zastrow, Ruth Hüttenhain
Profiling the proximal proteome of the activated μ-opioid receptor. Nature chemical biology 20 (9) (2024)
Max B Sosa, Michelle C Y Chang
Solving the mystery of enediyne biosynthesis. Nature chemical biology 20 (9) (2024)
Qinheng Zheng, Ziyang Zhang, Keelan Z Guiley, Kevan M Shokat
Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D. Nature chemical biology 20 (9) (2024)
Krishna Neupane, Abhishek Narayan, Supratik Sen Mojumdar, Gaurav Adhikari, Craig R Garen, Michael T Woodside
Direct observation of prion-like propagation of protein misfolding templated by pathogenic mutants. Nature chemical biology 20 (9) (2024)
Shaoshuai Xie, Gang Li
A key to unlock ubiquitin ligase function. Nature chemical biology 20 (9) (2024)
Lei Yang, Yanan Huo, Man Wang, Dan Zhang, Tianai Zhang, Hao Wu, Xichen Rao, Haowei Meng, Shuming Yin, Jiale Mei, Dexin Zhang, Xi Chen, Jia Lv, Meizhen Liu, Yiyun Cheng, Yuting Guan, Bo Feng, Gaojie Song, Chengqi Yi, Mingyao Liu, Fanyi Zeng, Liren Wang, Dali Li
Engineering APOBEC3A deaminase for highly accurate and efficient base editing. Nature chemical biology 20 (9) (2024)