Mark Hedglin

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 20

Top Venues

Biochemistry

Nucleic acids research

Nature communications

The Journal of biological chemistry

Pennsylvania State University

University of Michigan (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Pennsylvania State University Jan 02 2018

United States

Assistant Professor :: Chemistry (University Park), Biochemistry & Molecular Biology (Hershey College of Medicine)

Pennsylvania State University Apr 01 2017 - Jan 01 2018

United States

Assistant Research Professor :: Chemistry

Pennsylvania State University - Mar 31 2017

United States

Postdoctoral Research Associate :: Chemistry

Education History

University of Michigan

United States

PHD :: Chemical Biology

Publications

Kara G Pytko, Rachel L Dannenberg, Kristin A Eckert, Mark Hedglin
Replication of [AT/TA] 25 Microsatellite Sequences by Human DNA Polymerase δ Holoenzymes Is Dependent on dNTP and RPA Levels. Biochemistry 63 (8) (2024)
Daniela Muoio, Natalie Laspata, Rachel L Dannenberg, Caroline Curry, Simone Darkoa-Larbi, Mark Hedglin, Shikhar Uttam, Elise Fouquerel
PARP2 promotes Break Induced Replication-mediated telomere fragility in response to replication stress. Nature communications 15 (1) (2024)
Kara G Pytko, Rachel L Dannenberg, Kristin A Eckert, Mark Hedglin
Replication of [AT/TA] 25 Microsatellite Sequences by Human DNA Polymerase δ Holoenzymes Is Dependent on dNTP and RPA Levels. Biochemistry 63 (8) (2024)
Jessica L Norris, Lindsey O Rogers, Kara G Pytko, Rachel L Dannenberg, Samuel Perreault, Vikas Kaushik, Sahiti Kuppa, Edwin Antony, Mark Hedglin
Replication protein A dynamically re-organizes on primer/template junctions to permit DNA polymerase δ holoenzyme assembly and initiation of DNA synthesis. Nucleic acids research 52 (13) (2024)
Kara G Pytko, Rachel L Dannenberg, Kristin A Eckert, Mark Hedglin
Replication of [AT/TA] 25 Microsatellite Sequences by Human DNA Polymerase δ Holoenzymes Is Dependent on dNTP and RPA Levels. Biochemistry 63 (8) (2024)
Daniela Muoio, Natalie Laspata, Rachel L Dannenberg, Caroline Curry, Simone Darkoa-Larbi, Mark Hedglin, Shikhar Uttam, Elise Fouquerel
PARP2 promotes Break Induced Replication-mediated telomere fragility in response to replication stress. Nature communications 15 (1) (2024)
Daniela Muoio, Natalie Laspata, Rachel L Dannenberg, Caroline Curry, Simone Darkoa-Larbi, Mark Hedglin, Shikhar Uttam, Elise Fouquerel
PARP2 promotes Break Induced Replication-mediated telomere fragility in response to replication stress. Nature communications 15 (1) (2024)
Kara G Pytko, Rachel L Dannenberg, Kristin A Eckert, Mark Hedglin
Replication of [AT/TA] 25 Microsatellite Sequences by Human DNA Polymerase δ Holoenzymes Is Dependent on dNTP and RPA Levels. Biochemistry 63 (8) (2024)
Kara G Pytko, Rachel L Dannenberg, Kristin A Eckert, Mark Hedglin
Replication of [AT/TA] 25 Microsatellite Sequences by Human DNA Polymerase δ Holoenzymes Is Dependent on dNTP and RPA Levels. Biochemistry 63 (8) (2024)
Daniela Muoio, Natalie Laspata, Rachel L Dannenberg, Caroline Curry, Simone Darkoa-Larbi, Mark Hedglin, Shikhar Uttam, Elise Fouquerel
PARP2 promotes Break Induced Replication-mediated telomere fragility in response to replication stress. Nature communications 15 (1) (2024)
Jessica L Norris, Lindsey O Rogers, Kara G Pytko, Rachel L Dannenberg, Samuel Perreault, Vikas Kaushik, Sahiti Kuppa, Edwin Antony, Mark Hedglin
Replication protein A dynamically re-organizes on primer/template junctions to permit DNA polymerase δ holoenzyme assembly and initiation of DNA synthesis. Nucleic acids research 52 (13) (2024)
Jessica L Norris, Lindsey O Rogers, Kara G Pytko, Rachel L Dannenberg, Samuel Perreault, Vikas Kaushik, Sahiti Kuppa, Edwin Antony, Mark Hedglin
Replication protein A dynamically re-organizes on primer/template junctions to permit DNA polymerase δ holoenzyme assembly and initiation of DNA synthesis. Nucleic acids research (2024)
Jessica L Norris, Lindsey O Rogers, Kara G Pytko, Rachel L Dannenberg, Samuel Perreault, Vikas Kaushik, Sahiti Kuppa, Edwin Antony, Mark Hedglin
Replication protein A dynamically re-organizes on primer/template junctions to permit DNA polymerase δ holoenzyme assembly and initiation of DNA synthesis. Nucleic acids research 52 (13) (2024)
Nicole M Hoitsma, Jessica Norris, Thu H Khoang, Vikas Kaushik, Rahul Chadda, Edwin Antony, Mark Hedglin, Bret D Freudenthal
Mechanistic insight into AP-endonuclease 1 cleavage of abasic sites at stalled replication fork mimics. Nucleic acids research (2023)
Susanna Stroik, Juan Carvajal-Garcia, Dipika Gupta, Alyssa Edwards, Adam Luthman, David W Wyatt, Rachel L Dannenberg, Wanjuan Feng, Thomas A Kunkel, Gaorav P Gupta, Mark Hedglin, Richard D Wood, Sylvie Doublié, Eli Rothenberg, Dale A Ramsden
Stepwise requirements for polymerases δ and θ in theta-mediated end joining. Nature (2023)
Rachel L Dannenberg, Joseph A Cardina, Kara G Pytko, Mark Hedglin
Tracking of progressing human DNA polymerase δ holoenzymes reveals distributions of DNA lesion bypass activities. Nucleic acids research 50 (17) (2022)
Mingjie Li, Bhaswati Sengupta, Stephen J Benkovic, Tae-Hee Lee, Mark Hedglin
PCNA Monoubiquitination Is Regulated by Diffusion of Rad6/Rad18 Complexes along RPA Filaments. Biochemistry 59 (49) (2020)
Christl Gaubitz, Xingchen Liu, Joseph Magrino, Nicholas P Stone, Jacob T Landeck, Mark Hedglin, Brian A Kelch
Structure of the human clamp loader reveals an autoinhibited conformation of a substrate-bound AAA+ switch. Proceedings of the National Academy of Sciences of the United States of America 117 (38) (2020)
Mingjie Li, Leah Larsen, Mark Hedglin
Rad6/Rad18 Competes with DNA Polymerases η and δ for PCNA Encircling DNA. Biochemistry 59 (4) (2020)
Mark Hedglin, Mahesh Aitha, Anthony M Pedley, Stephen J Benkovic
Replication protein A dynamically regulates monoubiquitination of proliferating cell nuclear antigen. The Journal of biological chemistry 294 (13) (2019)

Mark Hedglin.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Mark Hedglin