Bret D Freudenthal

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 31

Top Venues

Nucleic acids research

Nature communications

Genes

bioRxiv : the preprint server for biology

University of Kansas Medical Center

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Kansas Medical Center Oct 01 2015

United States

Assistant Professor :: Biochemistry and Molecular Biology

Publications

Shijun Gao, Peyton N Oden, Benjamin J Ryan, Haozhe Yang, Bret D Freudenthal, Marc M Greenberg
Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase β. Nucleic acids research (2024)
Shijun Gao, Peyton N Oden, Benjamin J Ryan, Haozhe Yang, Bret D Freudenthal, Marc M Greenberg
Biochemical and Structural Characterization of Fapy•dG Replication by Human DNA Polymerase β. bioRxiv : the preprint server for biology (2024)
Natasha Ramakrishnan, Tyler M Weaver, Lindsey N Aubuchon, Ayda Woldegerima, Taylor Just, Kevin Song, Alessandro Vindigni, Bret D Freudenthal, Priyanka Verma
Nucleolytic processing of abasic sites underlies PARP inhibitor hypersensitivity in ALC1-deficient BRCA mutant cancer cells. Nature communications 15 (1) (2024)
Shijun Gao, Peyton N Oden, Benjamin J Ryan, Haozhe Yang, Bret D Freudenthal, Marc M Greenberg
Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase β. Nucleic acids research 52 (9) (2024)
Shijun Gao, Peyton N Oden, Benjamin J Ryan, Haozhe Yang, Bret D Freudenthal, Marc M Greenberg
Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase β. Nucleic acids research (2024)
Shijun Gao, Peyton N Oden, Benjamin J Ryan, Haozhe Yang, Bret D Freudenthal, Marc M Greenberg
Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase β. Nucleic acids research 52 (9) (2024)
Shijun Gao, Peyton N Oden, Benjamin J Ryan, Haozhe Yang, Bret D Freudenthal, Marc M Greenberg
Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase β. Nucleic acids research 52 (9) (2024)
Shijun Gao, Peyton N Oden, Benjamin J Ryan, Haozhe Yang, Bret D Freudenthal, Marc M Greenberg
Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase β. Nucleic acids research 52 (9) (2024)
Natasha Ramakrishnan, Tyler M Weaver, Lindsey N Aubuchon, Ayda Woldegerima, Taylor Just, Kevin Song, Alessandro Vindigni, Bret D Freudenthal, Priyanka Verma
Nucleolytic processing of abasic sites underlies PARP inhibitor hypersensitivity in ALC1-deficient BRCA mutant cancer cells. Nature communications 15 (1) (2024)
Shijun Gao, Peyton N Oden, Benjamin J Ryan, Haozhe Yang, Bret D Freudenthal, Marc M Greenberg
Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase β. Nucleic acids research (2024)
Shijun Gao, Peyton N Oden, Benjamin J Ryan, Haozhe Yang, Bret D Freudenthal, Marc M Greenberg
Biochemical and Structural Characterization of Fapy•dG Replication by Human DNA Polymerase β. bioRxiv : the preprint server for biology (2024)
Shijun Gao, Peyton N Oden, Benjamin J Ryan, Haozhe Yang, Bret D Freudenthal, Marc M Greenberg
Biochemical and Structural Characterization of Fapy•dG Replication by Human DNA Polymerase β. bioRxiv : the preprint server for biology (2024)
Natasha Ramakrishnan, Tyler M Weaver, Lindsey N Aubuchon, Ayda Woldegerima, Taylor Just, Kevin Song, Alessandro Vindigni, Bret D Freudenthal, Priyanka Verma
Nucleolytic processing of abasic sites underlies PARP inhibitor hypersensitivity in ALC1-deficient BRCA mutant cancer cells. Nature communications 15 (1) (2024)
Natasha Ramakrishnan, Tyler M Weaver, Lindsey N Aubuchon, Ayda Woldegerima, Taylor Just, Kevin Song, Alessandro Vindigni, Bret D Freudenthal, Priyanka Verma
Nucleolytic processing of abasic sites underlies PARP inhibitor hypersensitivity in ALC1-deficient BRCA mutant cancer cells. Nature communications 15 (1) (2024)
Griffin A Welfer, Veniamin A Borin, Luis M Cortez, Patricia L Opresko, Pratul K Agarwal, Bret D Freudenthal
Altered Nucleotide Insertion Mechanisms of Disease-Associated TERT Variants. Genes 14 (2) (2023)
Griffin A Welfer, Bret D Freudenthal
Recent advancements in the structural biology of human telomerase and their implications for improved design of cancer therapeutics. NAR cancer 5 (1) (2023)
Griffin A Welfer, Veniamin A Borin, Luis M Cortez, Patricia L Opresko, Pratul K Agarwal, Bret D Freudenthal
Altered Nucleotide Insertion Mechanisms of Disease-Associated TERT Variants. Genes 14 (2) (2023)
Griffin A Welfer, Veniamin A Borin, Luis M Cortez, Patricia L Opresko, Pratul K Agarwal, Bret D Freudenthal
Altered Nucleotide Insertion Mechanisms of Disease-Associated TERT Variants. Genes 14 (2) (2023)
Griffin A Welfer, Veniamin A Borin, Luis M Cortez, Patricia L Opresko, Pratul K Agarwal, Bret D Freudenthal
Altered Nucleotide Insertion Mechanisms of Disease-Associated TERT Variants. Genes 14 (2) (2023)
Griffin A Welfer, Bret D Freudenthal
Recent advancements in the structural biology of human telomerase and their implications for improved design of cancer therapeutics. NAR cancer 5 (1) (2023)
Nicole M Hoitsma, Jessica Norris, Thu H Khoang, Vikas Kaushik, Rahul Chadda, Edwin Antony, Mark Hedglin, Bret D Freudenthal
Mechanistic insight into AP-endonuclease 1 cleavage of abasic sites at stalled replication fork mimics. Nucleic acids research (2023)
Amy M Whitaker, Wesley J Stark, Bret D Freudenthal
Processing oxidatively damaged bases at DNA strand breaks by APE1. Nucleic acids research 50 (16) (2022)
Tyler M Weaver, Nicole M Hoitsma, Jonah J Spencer, Lokesh Gakhar, Nicholas J Schnicker, Bret D Freudenthal
Structural basis for APE1 processing DNA damage in the nucleosome. Nature communications 13 (1) (2022)
Benjamin J Ryan, Haozhe Yang, Jan Henric T Bacurio, Mallory R Smith, Ashis K Basu, Marc M Greenberg, Bret D Freudenthal
Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication. Journal of the American Chemical Society 144 (18) (2022)
Tyler M Weaver, Timothy H Click, Thu H Khoang, M Todd Washington, Pratul K Agarwal, Bret D Freudenthal
Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1. Nature communications 13 (1) (2022)
Fausto A Varela, Bret D Freudenthal
Mechanism of Deoxyguanosine Diphosphate Insertion by Human DNA Polymerase β. Biochemistry 60 (5) (2021)
Max S Fairlamb, Amy M Whitaker, Fletcher E Bain, Maria Spies, Bret D Freudenthal
Construction of a Three-Color Prism-Based TIRF Microscope to Study the Interactions and Dynamics of Macromolecules. Biology 10 (7) (2021)
Samantha L Sanford, Griffin A Welfer, Bret D Freudenthal, Patricia L Opresko
Mechanisms of telomerase inhibition by oxidized and therapeutic dNTPs. Nature communications 11 (1) (2020)
Matthew A Schaich, Samantha L Sanford, Griffin A Welfer, Samuel A Johnson, Thu H Khoang, Patricia L Opresko, Bret D Freudenthal
Mechanisms of nucleotide selection by telomerase. eLife 9 (2020)
Max S Fairlamb, Amy M Whitaker, Bret D Freudenthal
Apurinic/apyrimidinic (AP) endonuclease 1 processing of AP sites with 5' mismatches. Acta crystallographica. Section D, Structural biology 74 (Pt 8) (2018)
Matthew A Schaich, Mallory R Smith, Ashley S Cloud, Sean M Holloran, Bret D Freudenthal
Structures of a DNA Polymerase Inserting Therapeutic Nucleotide Analogues. Chemical research in toxicology 30 (11) (2017)

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Publication Activity (10 Years)

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Bret D Freudenthal