Markus Schirle

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 28

Top Venues

ACS chemical biology

Nature chemical biology

Journal of the American Chemical Society

Chemical science

This page only lists publications with an associated author ORCID identifier.

Publications

Jason R Thomas, Claude Shelton, Jason Murphy, Scott Brittain, Mark-Anthony Bray, Peter Aspesi, John Concannon, Frederick J King, Robert J Ihry, Daniel J Ho, Martin Henault, Andrea Hadjikyriacou, Marilisa Neri, Frederic D Sigoillot, Helen T Pham, Matthew Shum, Louise Barys, Michael D Jones, Eric J Martin, Anke Blechschmidt, Sébastien Rieffel, Thomas J Troxler, Felipa A Mapa, Jeremy L Jenkins, Rishi K Jain, Peter S Kutchukian, Markus Schirle, Steffen Renner
Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical Matter─Compounds with Novel Mechanisms from High-Throughput Screening Profiles. ACS chemical biology 19 (4) (2024)
Flor A Gowans, Danny Q Thach, Zhouyang Zhu, Yangzhi Wang, Belen E Altamirano Poblano, Dustin Dovala, John A Tallarico, Jeffrey M McKenna, Markus Schirle, Thomas J Maimone, Daniel K Nomura
Ophiobolin A Covalently Targets Mitochondrial Complex IV Leading to Metabolic Collapse in Cancer Cells. ACS chemical biology (2024)
Flor A Gowans, Danny Q Thach, Zhouyang Zhu, Yangzhi Wang, Belen E Altamirano Poblano, Dustin Dovala, John A Tallarico, Jeffrey M McKenna, Markus Schirle, Thomas J Maimone, Daniel K Nomura
Ophiobolin A Covalently Targets Mitochondrial Complex IV Leading to Metabolic Collapse in Cancer Cells. ACS chemical biology (2024)
Jason R Thomas, Claude Shelton, Jason Murphy, Scott Brittain, Mark-Anthony Bray, Peter Aspesi, John Concannon, Frederick J King, Robert J Ihry, Daniel J Ho, Martin Henault, Andrea Hadjikyriacou, Marilisa Neri, Frederic D Sigoillot, Helen T Pham, Matthew Shum, Louise Barys, Michael D Jones, Eric J Martin, Anke Blechschmidt, Sébastien Rieffel, Thomas J Troxler, Felipa A Mapa, Jeremy L Jenkins, Rishi K Jain, Peter S Kutchukian, Markus Schirle, Steffen Renner
Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical Matter─Compounds with Novel Mechanisms from High-Throughput Screening Profiles. ACS chemical biology 19 (4) (2024)
Jason R Thomas, Claude Shelton, Jason Murphy, Scott Brittain, Mark-Anthony Bray, Peter Aspesi, John Concannon, Frederick J King, Robert J Ihry, Daniel J Ho, Martin Henault, Andrea Hadjikyriacou, Marilisa Neri, Frederic D Sigoillot, Helen T Pham, Matthew Shum, Louise Barys, Michael D Jones, Eric J Martin, Anke Blechschmidt, Sébastien Rieffel, Thomas J Troxler, Felipa A Mapa, Jeremy L Jenkins, Rishi K Jain, Peter S Kutchukian, Markus Schirle, Steffen Renner
Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical Matter─Compounds with Novel Mechanisms from High-Throughput Screening Profiles. ACS chemical biology 19 (4) (2024)
Jason R Thomas, Claude Shelton, Jason Murphy, Scott Brittain, Mark-Anthony Bray, Peter Aspesi, John Concannon, Frederick J King, Robert J Ihry, Daniel J Ho, Martin Henault, Andrea Hadjikyriacou, Marilisa Neri, Frederic D Sigoillot, Helen T Pham, Matthew Shum, Louise Barys, Michael D Jones, Eric J Martin, Anke Blechschmidt, Sébastien Rieffel, Thomas J Troxler, Felipa A Mapa, Jeremy L Jenkins, Rishi K Jain, Peter S Kutchukian, Markus Schirle, Steffen Renner
Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical Matter─Compounds with Novel Mechanisms from High-Throughput Screening Profiles. ACS chemical biology 19 (4) (2024)
Flor A Gowans, Danny Q Thach, Zhouyang Zhu, Yangzhi Wang, Belen E Altamirano Poblano, Dustin Dovala, John A Tallarico, Jeffrey M McKenna, Markus Schirle, Thomas J Maimone, Daniel K Nomura
Ophiobolin A Covalently Targets Mitochondrial Complex IV Leading to Metabolic Collapse in Cancer Cells. ACS chemical biology 19 (6) (2024)
Jason R Thomas, Claude Shelton, Jason Murphy, Scott Brittain, Mark-Anthony Bray, Peter Aspesi, John Concannon, Frederick J King, Robert J Ihry, Daniel J Ho, Martin Henault, Andrea Hadjikyriacou, Marilisa Neri, Frederic D Sigoillot, Helen T Pham, Matthew Shum, Louise Barys, Michael D Jones, Eric J Martin, Anke Blechschmidt, Sébastien Rieffel, Thomas J Troxler, Felipa A Mapa, Jeremy L Jenkins, Rishi K Jain, Peter S Kutchukian, Markus Schirle, Steffen Renner
Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical Matter─Compounds with Novel Mechanisms from High-Throughput Screening Profiles. ACS chemical biology 19 (4) (2024)
Jason R Thomas, Claude Shelton, Jason Murphy, Scott Brittain, Mark-Anthony Bray, Peter Aspesi, John Concannon, Frederick J King, Robert J Ihry, Daniel J Ho, Martin Henault, Andrea Hadjikyriacou, Marilisa Neri, Frederic D Sigoillot, Helen T Pham, Matthew Shum, Louise Barys, Michael D Jones, Eric J Martin, Anke Blechschmidt, Sébastien Rieffel, Thomas J Troxler, Felipa A Mapa, Jeremy L Jenkins, Rishi K Jain, Peter S Kutchukian, Markus Schirle, Steffen Renner
Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical Matter─Compounds with Novel Mechanisms from High-Throughput Screening Profiles. ACS chemical biology (2024)
Jason R Thomas, Claude Shelton, Jason Murphy, Scott Brittain, Mark-Anthony Bray, Peter Aspesi, John Concannon, Frederick J King, Robert J Ihry, Daniel J Ho, Martin Henault, Andrea Hadjikyriacou, Marilisa Neri, Frederic D Sigoillot, Helen T Pham, Matthew Shum, Louise Barys, Michael D Jones, Eric J Martin, Anke Blechschmidt, Sébastien Rieffel, Thomas J Troxler, Felipa A Mapa, Jeremy L Jenkins, Rishi K Jain, Peter S Kutchukian, Markus Schirle, Steffen Renner
Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical Matter─Compounds with Novel Mechanisms from High-Throughput Screening Profiles. ACS chemical biology 19 (4) (2024)
Flor A Gowans, Danny Q Thach, Zhouyang Zhu, Yangzhi Wang, Belen E Altamirano Poblano, Dustin Dovala, John A Tallarico, Jeffrey M McKenna, Markus Schirle, Thomas J Maimone, Daniel K Nomura
Ophiobolin A Covalently Targets Mitochondrial Complex IV Leading to Metabolic Collapse in Cancer Cells. ACS chemical biology 19 (6) (2024)
Nathaniel J Henning, Andrew G Manford, Jessica N Spradlin, Scott M Brittain, Erika Zhang, Jeffrey M McKenna, John A Tallarico, Markus Schirle, Michael Rape, Daniel K Nomura
Correction to "Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications". Journal of the American Chemical Society (2023)
Nafsika Forte, Dustin Dovala, Matthew J Hesse, Jeffrey M McKenna, John A Tallarico, Markus Schirle, Daniel K Nomura
Targeted Protein Degradation through E2 Recruitment. ACS chemical biology (2023)
Jie Li, Stephen M Canham, Hua Wu, Martin Henault, Lihao Chen, Guoxun Liu, Yu Chen, Gary Yu, Howard R Miller, Viktor Hornak, Scott M Brittain, Gregory A Michaud, Antonin Tutter, Wendy Broom, Mary Ellen Digan, Sarah M McWhirter, Kelsey E Sivick, Helen T Pham, Christine H Chen, George S Tria, Jeffery M McKenna, Markus Schirle, Xiaohong Mao, Thomas B Nicholson, Yuan Wang, Jeremy L Jenkins, Rishi K Jain, John A Tallarico, Sejal J Patel, Lianxing Zheng, Nathan T Ross, Charles Y Cho, Xuewu Zhang, Xiao-Chen Bai, Yan Feng
Activation of human STING by a molecular glue-like compound. Nature chemical biology (2023)
Ethan S Toriki, James W Papatzimas, Kaila Nishikawa, Dustin Dovala, Andreas O Frank, Matthew J Hesse, Daniela Dankova, Jae-Geun Song, Megan Bruce-Smythe, Heidi Struble, Francisco J Garcia, Scott M Brittain, Andrew C Kile, Lynn M McGregor, Jeffrey M McKenna, John A Tallarico, Markus Schirle, Daniel K Nomura
Rational Chemical Design of Molecular Glue Degraders. ACS central science 9 (5) (2023)
Nathaniel J Henning, Andrew G Manford, Jessica N Spradlin, Scott M Brittain, Erika Zhang, Jeffrey M McKenna, John A Tallarico, Markus Schirle, Michael Rape, Daniel K Nomura
Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications. Journal of the American Chemical Society 144 (2) (2022)
Annika C S Page, Spencer O Scholz, Katherine N Keenan, Jessica N Spradlin, Bridget P Belcher, Scott M Brittain, John A Tallarico, Jeffery M McKenna, Markus Schirle, Daniel K Nomura, F Dean Toste
Photo-Brook rearrangement of acyl silanes as a strategy for photoaffinity probe design. Chemical science 13 (13) (2022)
Caleb R Hoopes, Francisco J Garcia, Akash M Sarkar, Nicholas J Kuehl, David T Barkan, Nicole L Collins, Glenna E Meister, Taylor R Bramhall, Chien-Hsiang Hsu, Michael D Jones, Markus Schirle, Michael T Taylor
Donor-Acceptor Pyridinium Salts for Photo-Induced Electron-Transfer-Driven Modification of Tryptophan in Peptides, Proteins, and Proteomes Using Visible Light. Journal of the American Chemical Society 144 (14) (2022)
Nathaniel J Henning, Lydia Boike, Jessica N Spradlin, Carl C Ward, Gang Liu, Erika Zhang, Bridget P Belcher, Scott M Brittain, Matthew J Hesse, Dustin Dovala, Lynn M McGregor, Rachel Valdez Misiolek, Lindsey W Plasschaert, David J Rowlands, Feng Wang, Andreas O Frank, Daniel Fuller, Abigail R Estes, Katelyn L Randal, Anoohya Panidapu, Jeffery M McKenna, John A Tallarico, Markus Schirle, Daniel K Nomura
Deubiquitinase-targeting chimeras for targeted protein stabilization. Nature chemical biology 18 (4) (2022)
Angel Gonzalez-Valero, Audrey G Reeves, Annika C S Page, Patrick J Moon, Edward Miller, Katia Coulonval, Steven W M Crossley, Xiao Xie, Dan He, Patricia Z Musacchio, Alec H Christian, Jeffrey M McKenna, Richard A Lewis, Eric Fang, Dustin Dovala, Yipin Lu, Lynn M McGregor, Markus Schirle, John A Tallarico, Pierre P Roger, F Dean Toste, Christopher J Chang
An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4. Journal of the American Chemical Society (2022)
David Remillard, Nikolas A Savage, Alexia T Kedves, Joshiawa Paulk, Xin Chen, Francisco J Garcia, Michael J Romanowski, Patricia A Horton, Jason Murphy, Markus Schirle, Edmund M Harrington, Matthew B Maxwell, Helen Trinh Pham, Igor Maksimovic, Jason R Thomas, William C Forrester
Chemoproteomics Enabled Discovery of Selective Probes for NuA4 Factor BRD8. ACS chemical biology 16 (11) (2021)
Gabi Schutzius, Christian Kolter, Sebastian Bergling, Federico Tortelli, Florian Fuchs, Steffen Renner, Vito Guagnano, Simona Cotesta, Heinrich Rueeger, Michael Faller, Laure Bouchez, Adrian Salathe, Florian Nigsch, Shola M Richards, Malvina Louis, Viktoria Gruber, Alexandra Aebi, Jonathan Turner, Frederic Grandjean, Jun Li, Chris Dimitri, Jason Ray Thomas, Markus Schirle, Jutta Blank, Peter Drueckes, Andrea Vaupel, Ralph Tiedt, Paul W Manley, Julia Klopp, Rene Hemmig, Florence Zink, Nelly Leroy, Walter Carbone, Guglielmo Roma, Caroline Gubser Keller, Natalie Dales, Armin Beyerbach, Alfred Zimmerlin, Debora Bonenfant, Remi Terranova, Amy Berwick, Sukhdeep Sahambi, Aimee Reynolds, Lori L Jennings, Heinz Ruffner, Peter Tarsa, Tewis Bouwmeester, Vickie Driver, Mathias Frederiksen, Felix Lohmann, Susan Kirkland
BET bromodomain inhibitors regulate keratinocyte plasticity. Nature chemical biology 17 (3) (2021)
Yosuke Isobe, Mikiko Okumura, Lynn M McGregor, Scott M Brittain, Michael D Jones, Xiaoyou Liang, Ross White, William Forrester, Jeffrey M McKenna, John A Tallarico, Markus Schirle, Thomas J Maimone, Daniel K Nomura
Manumycin polyketides act as molecular glues between UBR7 and P53. Nature chemical biology 16 (11) (2020)
Bingqi Tong, Jessica N Spradlin, Luiz F T Novaes, Erika Zhang, Xirui Hu, Malte Moeller, Scott M Brittain, Lynn M McGregor, Jeffrey M McKenna, John A Tallarico, Markus Schirle, Thomas J Maimone, Daniel K Nomura
A Nimbolide-Based Kinase Degrader Preferentially Degrades Oncogenic BCR-ABL. ACS chemical biology 15 (7) (2020)
Carl C Ward, Jordan I Kleinman, Scott M Brittain, Patrick S Lee, Clive Yik Sham Chung, Kenneth Kim, Yana Petri, Jason R Thomas, John A Tallarico, Jeffrey M McKenna, Markus Schirle, Daniel K Nomura
Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS chemical biology 14 (11) (2019)
Nathan T Ross, Felix Lohmann, Seth Carbonneau, Aleem Fazal, Wilhelm A Weihofen, Scott Gleim, Michael Salcius, Frederic D Sigoillot, Martin Henault, Sarah H Carl, Juan B Rodríguez-Molina, Howard R Miller, Scott M Brittain, Jason Murphy, Mark Zambrowski, Geoffrey Boynton, Yuan Wang, Aye Chen, Gregory J Molind, Johannes H Wilbertz, Caroline G Artus-Revel, Min Jia, Favour A Akinjiyan, Jonathan Turner, Judith Knehr, Walter Carbone, Sven Schuierer, John S Reece-Hoyes, Kevin Xie, Chitra Saran, Eric T Williams, Guglielmo Roma, Matt Spencer, Jeremy L Jenkins, Elizabeth L George, Jason R Thomas, Gregory A Michaud, Markus Schirle, John A Tallarico, Lori A Passmore, Jeffrey A Chao, Rohan E J Beckwith
CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma. Nature chemical biology 16 (1) (2019)
Andrew C Wang, Helen T Pham, Jennifer M Lipps, Scott M Brittain, Edmund Harrington, Yuan Wang, Fred J King, Carsten Russ, Xuewen Pan, Dominic Hoepfner, John Tallarico, Yan Feng, Rishi K Jain, Markus Schirle, Jason Ray Thomas
Previously Uncharacterized Vacuolar-type ATPase Binding Site Discovered from Structurally Similar Compounds with Distinct Mechanisms of Action. ACS chemical biology 14 (1) (2018)
Ireos Filipuzzi, Jason Ray Thomas, Verena Pries, David Estoppey, Michael Salcius, Christian Studer, Markus Schirle, Dominic Hoepfner
Direct Interaction of Chivosazole F with Actin Elicits Cell Responses Similar to Latrunculin A but Distinct from Chondramide. ACS chemical biology 12 (9) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Markus Schirle