Michael A Letavic

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 8

Top Venues

Journal of medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Christine F Gelin, Brice Stenne, Heather Coate, Afton Hiscox, Akinola Soyode-Johnson, Jessica L Wall, Brian Lord, Jeffrey Schoellerman, Kevin J Coe, Kai Wang, Jesus Alcázar, Christa C Chrovian, Curt A Dvorak, Nicholas I Carruthers, Tatiana Koudriakova, Bartosz Balana, Michael A Letavic
Discovery of a Series of Substituted 1 H -((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators. Journal of medicinal chemistry 66 (4) (2023)
Christine F Gelin, Brice Stenne, Heather Coate, Afton Hiscox, Akinola Soyode-Johnson, Jessica L Wall, Brian Lord, Jeffrey Schoellerman, Kevin J Coe, Kai Wang, Jesus Alcázar, Christa C Chrovian, Curt A Dvorak, Nicholas I Carruthers, Tatiana Koudriakova, Bartosz Balana, Michael A Letavic
Discovery of a Series of Substituted 1 H -((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators. Journal of medicinal chemistry (2023)
Christine F Gelin, Brice Stenne, Heather Coate, Afton Hiscox, Akinola Soyode-Johnson, Jessica L Wall, Brian Lord, Jeffrey Schoellerman, Kevin J Coe, Kai Wang, Jesus Alcázar, Christa C Chrovian, Curt A Dvorak, Nicholas I Carruthers, Tatiana Koudriakova, Bartosz Balana, Michael A Letavic
Discovery of a Series of Substituted 1 H -((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators. Journal of medicinal chemistry 66 (4) (2023)
Christine F Gelin, Brice Stenne, Heather Coate, Afton Hiscox, Akinola Soyode-Johnson, Jessica L Wall, Brian Lord, Jeffrey Schoellerman, Kevin J Coe, Kai Wang, Jesus Alcázar, Christa C Chrovian, Curt A Dvorak, Nicholas I Carruthers, Tatiana Koudriakova, Bartosz Balana, Michael A Letavic
Discovery of a Series of Substituted 1 H -((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators. Journal of medicinal chemistry 66 (4) (2023)
Christine F Gelin, Brice Stenne, Heather Coate, Afton Hiscox, Akinola Soyode-Johnson, Jessica L Wall, Brian Lord, Jeffrey Schoellerman, Kevin J Coe, Kai Wang, Jesus Alcázar, Christa C Chrovian, Curt A Dvorak, Nicholas I Carruthers, Tatiana Koudriakova, Bartosz Balana, Michael A Letavic
Discovery of a Series of Substituted 1 H -((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators. Journal of medicinal chemistry 66 (4) (2023)
Christa C Chrovian, Akinola Soyode-Johnson, Brice Stenne, Daniel J Pippel, Jeffrey Schoellerman, Brian Lord, Alexandra S Needham, Chungfang Xia, Kevin J Coe, Kia Sepassi, Freddy Schoetens, Brian Scott, Leslie Nguyen, Xiaohui Jiang, Tatiana Koudriakova, Bartosz Balana, Michael A Letavic
Design, Synthesis, and Preclinical Evaluation of 3-Methyl-6-(5-thiophenyl)-1,3-dihydro-imidazo[4,5-b]pyridin-2-ones as Selective GluN2B Negative Allosteric Modulators for the Treatment of Mood Disorders. Journal of medicinal chemistry 63 (17) (2020)
Christa C Chrovian, Akinola Soyode-Johnson, Alexander A Peterson, Christine F Gelin, Xiaohu Deng, Curt A Dvorak, Nicholas I Carruthers, Brian Lord, Ian Fraser, Leah Aluisio, Kevin J Coe, Brian Scott, Tatiana Koudriakova, Freddy Schoetens, Kia Sepassi, David J Gallacher, Anindya Bhattacharya, Michael A Letavic
A Dipolar Cycloaddition Reaction To Access 6-Methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Antagonist Clinical Candidate. Journal of medicinal chemistry 61 (1) (2017)
Michael A Letavic, Brad M Savall, Brett D Allison, Leah Aluisio, Jose Ignacio Andres, Meri De Angelis, Hong Ao, Derek A Beauchamp, Pascal Bonaventure, Stewart Bryant, Nicholas I Carruthers, Marc Ceusters, Kevin J Coe, Curt A Dvorak, Ian C Fraser, Christine F Gelin, Tatiana Koudriakova, Jimmy Liang, Brian Lord, Timothy W Lovenberg, Monicah A Otieno, Freddy Schoetens, Devin M Swanson, Qi Wang, Alan D Wickenden, Anindya Bhattacharya
4-Methyl-6,7-dihydro-4H-triazolo[4,5-c]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate. Journal of medicinal chemistry 60 (11) (2017)

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Publication Activity (10 Years)

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Michael A Letavic