Michael E O'Donnell (Mike E O'Donnell, Michael O'Donnell, Mike O'Donnell)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 55

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature structural & molecular biology

Science advances

eLife

Howard Hughes Medical Institute

University of Michigan (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Howard Hughes Medical Institute

United States

Investigator

Rockefeller University

United States

Professor/Head of Laboratory

Education History

University of Michigan

United States

PHD :: Biochemistry

University of Portland

United States

BSC :: Biochemistry

Publications

Feng Wang, Qing He, Nina Y Yao, Michael E O'Donnell, Huilin Li
The human ATAD5 has evolved unique structural elements to function exclusively as a PCNA unloader. Nature structural & molecular biology (2024)
Fengwei Zheng, Nina Y Yao, Roxana E Georgescu, Huilin Li, Michael E O'Donnell
Structure of the PCNA unloader Elg1-RFC. Science advances 10 (9) (2024)
Fengwei Zheng, Nina Y Yao, Roxana E Georgescu, Huilin Li, Michael E O'Donnell
Structure of the PCNA unloader Elg1-RFC. Science advances 10 (9) (2024)
Kendra C Marcus, Yongjian Huang, Subu Subramanian, Christine L Gee, Kent Gorday, Sam Ghaffari-Kashani, Xiao Ran Luo, Lisa Zheng, Michael E O'Donnell, Sriram Subramaniam, John Kuriyan
Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nature structural & molecular biology (2024)
Qing He, Feng Wang, Michael E O'Donnell, Huilin Li
Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC. Proceedings of the National Academy of Sciences of the United States of America 121 (18) (2024)
Feng Wang, Qing He, Nina Y Yao, Michael E O'Donnell, Huilin Li
The human ATAD5 has evolved unique structural elements to function exclusively as a PCNA unloader. Nature structural & molecular biology (2024)
Kendra C Marcus, Yongjian Huang, Subu Subramanian, Christine L Gee, Kent Gorday, Sam Ghaffari-Kashani, Xiao Ran Luo, Lisa Zheng, Michael E O'Donnell, Sriram Subramaniam, John Kuriyan
Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nature structural & molecular biology 31 (3) (2024)
Zuanning Yuan, Roxana E Georgescu, Nina Y Yao, Olga Yurieva, Michael E O'Donnell, Huilin Li
Mechanism of PCNA loading by Ctf18-RFC for leading-strand DNA synthesis. Science (New York, N.Y.) 385 (6708) (2024)
Kendra C Marcus, Yongjian Huang, Subu Subramanian, Christine L Gee, Kent Gorday, Sam Ghaffari-Kashani, Xiao Ran Luo, Lisa Zheng, Michael E O'Donnell, Sriram Subramaniam, John Kuriyan
Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nature structural & molecular biology (2024)
Zuanning Yuan, Roxana E Georgescu, Nina Y Yao, Olga Yurieva, Michael E O'Donnell, Huilin Li
Mechanism of PCNA loading by Ctf18-RFC for leading-strand DNA synthesis. Science (New York, N.Y.) 385 (6708) (2024)
Qing He, Feng Wang, Michael E O'Donnell, Huilin Li
Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC. Proceedings of the National Academy of Sciences of the United States of America 121 (18) (2024)
Zuanning Yuan, Roxana E Georgescu, Nina Y Yao, Olga Yurieva, Michael E O'Donnell, Huilin Li
Mechanism of PCNA loading by Ctf18-RFC for leading-strand DNA synthesis. Science (New York, N.Y.) 385 (6708) (2024)
Kendra C Marcus, Yongjian Huang, Subu Subramanian, Christine L Gee, Kent Gorday, Sam Ghaffari-Kashani, Xiao Ran Luo, Lisa Zheng, Michael E O'Donnell, Sriram Subramaniam, John Kuriyan
Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nature structural & molecular biology 31 (3) (2024)
Kendra C Marcus, Yongjian Huang, Subu Subramanian, Christine L Gee, Kent Gorday, Sam Ghaffari-Kashani, Xiao Ran Luo, Lisa Zheng, Michael E O'Donnell, Sriram Subramaniam, John Kuriyan
Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nature structural & molecular biology 31 (3) (2024)
Feng Wang, Qing He, Nina Y Yao, Michael E O'Donnell, Huilin Li
The human ATAD5 has evolved unique structural elements to function exclusively as a PCNA unloader. Nature structural & molecular biology (2024)
Qing He, Feng Wang, Michael E O'Donnell, Huilin Li
Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC. Proceedings of the National Academy of Sciences of the United States of America 121 (18) (2024)
Feng Wang, Qing He, Nina Y Yao, Michael E O'Donnell, Huilin Li
The human ATAD5 has evolved unique structural elements to function exclusively as a PCNA unloader. Nature structural & molecular biology (2024)
Fengwei Zheng, Nina Y Yao, Roxana E Georgescu, Huilin Li, Michael E O'Donnell
Structure of the PCNA unloader Elg1-RFC. Science advances 10 (9) (2024)
Fengwei Zheng, Nina Y Yao, Roxana E Georgescu, Huilin Li, Michael E O'Donnell
Structure of the PCNA unloader Elg1-RFC. Science advances 10 (9) (2024)
Zuanning Yuan, Roxana E Georgescu, Nina Y Yao, Olga Yurieva, Michael E O'Donnell, Huilin Li
Mechanism of PCNA loading by Ctf18-RFC for leading-strand DNA synthesis. Science (New York, N.Y.) 385 (6708) (2024)
Fengwei Zheng, Nina Y Yao, Roxana E Georgescu, Huilin Li, Michael E O'Donnell
Structure of the PCNA unloader Elg1-RFC. Science advances 10 (9) (2024)
Fengwei Zheng, Nina Y Yao, Roxana E Georgescu, Huilin Li, Michael E O'Donnell
Structure of the PCNA unloader Elg1-RFC. Science advances 10 (9) (2024)
Qing He, Feng Wang, Michael E O'Donnell, Huilin Li
Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC. Proceedings of the National Academy of Sciences of the United States of America 121 (18) (2024)
Qing He, Feng Wang, Nina Y Yao, Michael E O'Donnell, Huilin Li
Structures of the human leading strand Polε-PCNA holoenzyme. Nature communications 15 (1) (2024)
Qing He, Feng Wang, Michael E O'Donnell, Huilin Li
Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC. Proceedings of the National Academy of Sciences of the United States of America 121 (18) (2024)
Kendra C Marcus, Yongjian Huang, Subu Subramanian, Christine L Gee, Kent Gorday, Sam Ghaffari-Kashani, Xiao Ran Luo, Lisa Zheng, Michael E O'Donnell, Sriram Subramaniam, John Kuriyan
Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nature structural & molecular biology 31 (3) (2024)
Kendra C Marcus, Yongjian Huang, Subu Subramanian, Christine L Gee, Kent Gorday, Sam Ghaffari-Kashani, Xiao Ran Luo, Lisa Zheng, Michael E O'Donnell, Sriram Subramaniam, John Kuriyan
Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nature structural & molecular biology 31 (3) (2024)
Qing He, Feng Wang, Michael E O'Donnell, Huilin Li
Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC. Proceedings of the National Academy of Sciences of the United States of America 121 (18) (2024)
Lance D Langston, Roxana E Georgescu, Michael E O'Donnell
Mechanism of eukaryotic origin unwinding is a dual helicase DNA shearing process. Proceedings of the National Academy of Sciences of the United States of America 120 (52) (2023)
Lance D Langston, Roxana E Georgescu, Michael E O'Donnell
Mechanism of eukaryotic origin unwinding is a dual helicase DNA shearing process. Proceedings of the National Academy of Sciences of the United States of America 120 (52) (2023)
Lance D Langston, Roxana E Georgescu, Michael E O'Donnell
Mechanism of eukaryotic origin unwinding is a dual helicase DNA shearing process. Proceedings of the National Academy of Sciences of the United States of America 120 (52) (2023)
Lance D Langston, Roxana E Georgescu, Michael E O'Donnell
Mechanism of eukaryotic origin unwinding is a dual helicase DNA shearing process. Proceedings of the National Academy of Sciences of the United States of America 120 (52) (2023)
Lance D Langston, Roxana E Georgescu, Michael E O'Donnell
Mechanism of eukaryotic origin unwinding is a dual helicase DNA shearing process. Proceedings of the National Academy of Sciences of the United States of America 120 (52) (2023)
Zuanning Yuan, Roxana Georgescu, Huilin Li, Michael E O'Donnell
Molecular choreography of primer synthesis by the eukaryotic Pol α-primase. Nature communications 14 (1) (2023)
Lance D Langston, Roxana E Georgescu, Michael E O'Donnell
Mechanism of eukaryotic origin unwinding is a dual helicase DNA shearing process. Proceedings of the National Academy of Sciences of the United States of America 120 (52) (2023)
Lance D Langston, Roxana E Georgescu, Michael E O'Donnell
Mechanism of eukaryotic origin unwinding is a dual helicase DNA shearing process. Proceedings of the National Academy of Sciences of the United States of America 120 (52) (2023)
Fengwei Zheng, Roxana E Georgescu, Nina Y Yao, Huilin Li, Michael E O'Donnell
Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair. eLife 11 (2022)
Fengwei Zheng, Roxana E Georgescu, Nina Y Yao, Michael E O'Donnell, Huilin Li
DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp. Nature structural & molecular biology 29 (4) (2022)
Huilin Li, Michael E O'Donnell, Brian Kelch
Unexpected new insights into DNA clamp loaders: Eukaryotic clamp loaders contain a second DNA site for recessed 5' ends that facilitates repair and signals DNA damage: Eukaryotic clamp loaders contain a second DNA site for recessed 5' ends that facilitates repair and signals DNA damage. BioEssays : news and reviews in molecular, cellular and developmental biology 44 (11) (2022)
Lance D Langston, Zuanning Yuan, Roxana E Georgescu, Huilin Li, Michael E O'Donnell
SV40 T-antigen uses a DNA shearing mechanism to initiate origin unwinding. Proceedings of the National Academy of Sciences of the United States of America 119 (49) (2022)
Nina Y Yao, Dan Zhang, Olga Yurieva, Michael E O'Donnell
CMG helicase can use ATPγS to unwind DNA: Implications for the rate-limiting step in the reaction mechanism. Proceedings of the National Academy of Sciences of the United States of America 119 (4) (2022)
Sai Li, Michael R Wasserman, Olga Yurieva, Lu Bai, Michael E O'Donnell, Shixin Liu
Origin recognition complex harbors an intrinsic nucleosome remodeling activity. Proceedings of the National Academy of Sciences of the United States of America 119 (42) (2022)
Jeremy T-H Chang, Shibai Li, Emily C Beckwitt, Thane Than, Cory Haluska, Joshua Chandanani, Michael E O'Donnell, Xiaolan Zhao, Shixin Liu
Smc5/6's multifaceted DNA binding capacities stabilize branched DNA structures. Nature communications 13 (1) (2022)
Huilin Li, Fengwei Zheng, Michael E O'Donnell
Water skating: How polymerase sliding clamps move on DNA. The FEBS journal (2021)
Zuanning Yuan, Roxana Georgescu, Lin Bai, Dan Zhang, Huilin Li, Michael E O'Donnell
DNA unwinding mechanism of a eukaryotic replicative CMG helicase. Nature communications 11 (1) (2020)
Grant D Schauer, Lisanne M Spenkelink, Jacob S Lewis, Olga Yurieva, Stefan H Mueller, Antoine M van Oijen, Michael E O'Donnell
Replisome bypass of a protein-based R-loop block by Pif1. Proceedings of the National Academy of Sciences of the United States of America 117 (48) (2020)
Zuanning Yuan, Roxana E Georgescu, Grant D Schauer, Michael E O'Donnell, Huilin Li
Structure of the polymerase ε holoenzyme and atomic model of the leading strand replisome. Nature communications 11 (1) (2020)
Fengwei Zheng, Roxana E Georgescu, Huilin Li, Michael E O'Donnell
Structure of eukaryotic DNA polymerase δ bound to the PCNA clamp while encircling DNA. Proceedings of the National Academy of Sciences of the United States of America 117 (48) (2020)
Zuanning Yuan, Roxana E Georgescu, Ruda de Luna Almeida Santos, Daniel Zhang, Lin Bai, Nina Y Yao, Gongpu Zhao, Michael E O'Donnell, Huilin Li
Ctf4 organizes sister replisomes and Pol α into a replication factory. eLife 8 (2019)
Kelsey S Whinn, Gurleen Kaur, Jacob S Lewis, Grant D Schauer, Stefan H Mueller, Slobodan Jergic, Hamish Maynard, Zhong Yan Gan, Matharishwan Naganbabu, Marcel P Bruchez, Michael E O'Donnell, Nicholas E Dixon, Antoine M van Oijen, Harshad Ghodke
Nuclease dead Cas9 is a programmable roadblock for DNA replication. Scientific reports 9 (1) (2019)
Lance D Langston, Michael E O'Donnell
An explanation for origin unwinding in eukaryotes. eLife 8 (2019)
Nina Y Yao, Michael E O'Donnell
Getting ready for DNA duplication. eLife 8 (2019)
Michael E O'Donnell, Huilin Li
The ring-shaped hexameric helicases that function at DNA replication forks. Nature structural & molecular biology 25 (2) (2018)
Lance D Langston, Michael E O'Donnell
Action of CMG with strand-specific DNA blocks supports an internal unwinding mode for the eukaryotic replicative helicase. eLife 6 (2017)
Lance D Langston, Ryan Mayle, Grant D Schauer, Olga Yurieva, Daniel Zhang, Nina Y Yao, Roxana E Georgescu, Michael E O'Donnell
Mcm10 promotes rapid isomerization of CMG-DNA for replisome bypass of lagging strand DNA blocks. eLife 6 (2017)

Michael E O'Donnell.css-eqlu8i{font-size:small;padding-left:4px;} (Mike E O'Donnell, Michael O'Donnell, Mike O'Donnell)

Publication Activity (10 Years)

Top Topics

Top Venues

Michael E O'Donnell (Mike E O'Donnell, Michael O'Donnell, Mike O'Donnell)