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Huilin Li (H Li, Hua Li)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 52

Top Venues

Nature communications

bioRxiv : the preprint server for biology

Proceedings of the National Academy of Sciences of the United States of America

Nature structural & molecular biology

Van Andel Institute

University of Science and Technology Beijing (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Van Andel Institute Aug 22o 2016

United States

Professor :: Structural Biology Program

Education History

University of Science and Technology Beijing Sep 1o 1990 - Mar 1o 1994

China

PHD :: Materials Physics

Publications

Zuanning Yuan, Roxana Georgescu, Huilin Li, Michael E O'Donnell
Molecular choreography of primer synthesis by the eukaryotic Pol α-primase. bioRxiv : the preprint server for biology (2023)
Fengwei Zheng, Roxana E Georgescu, Nina Y Yao, Michael E O'Donnell, Huilin Li
Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. bioRxiv : the preprint server for biology (2023)
Fengwei Zheng, Roxana E Georgescu, Nina Y Yao, Michael E O'Donnell, Huilin Li
Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. bioRxiv : the preprint server for biology (2023)
Xiang Feng, Michelle M Spiering, Ruda de Luna Almeida Santos, Stephen J Benkovic, Huilin Li
Structural basis of the T4 bacteriophage primosome assembly and primer synthesis. bioRxiv : the preprint server for biology (2023)
Hua Li, Digantkumar Chapla, Robert A Amos, Annapoorani Ramiah, Kelley W Moremen, Huilin Li
Structural basis for heparan sulfate co-polymerase action by the EXT1-2 complex. Nature chemical biology (2023)
Xiang Feng, Michelle M Spiering, Ruda de Luna Almeida Santos, Stephen J Benkovic, Huilin Li
Structural basis of the T4 bacteriophage primosome assembly and primer synthesis. Nature communications 14 (1) (2023)
Zuanning Yuan, Roxana Georgescu, Huilin Li, Michael E O'Donnell
Molecular choreography of primer synthesis by the eukaryotic Pol α-primase. Nature communications 14 (1) (2023)
Hao-Chi Hsu, Jason Wang, Abbey Kjellgren, Huilin Li, George N DeMartino
High-resolution structure of mammalian PI31â€"20S proteasome complex reveals mechanism of proteasome inhibition. bioRxiv : the preprint server for biology (2023)
Xiang Feng, Michelle M Spiering, Ruda de Luna Almeida Santos, Stephen J Benkovic, Huilin Li
Structural basis of the T4 bacteriophage primosome assembly and primer synthesis. bioRxiv : the preprint server for biology (2023)
Zuanning Yuan, Roxana Georgescu, Huilin Li, Michael E O'Donnell
Molecular choreography of primer synthesis by the eukaryotic Pol α-primase. bioRxiv : the preprint server for biology (2023)
Hua Li, Digantkumar Chapla, Robert A Amos, Annapoorani Ramiah, Kelley W Moremen, Huilin Li
Structural basis for heparan sulfate co-polymerase action by the EXT1-2 complex. Nature chemical biology (2023)
Hua Li, Digantkumar Chapla, Robert A Amos, Annapoorani Ramiah, Kelley W Moremen, Huilin Li
Structural basis for heparan sulfate co-polymerase action by the EXT1-2 complex. Nature chemical biology (2023)
E Sethe Burgie, Hua Li, Zachary T K Gannam, Katrice E McLoughlin, Richard David Vierstra, Huilin Li
The structure of Arabidopsis phytochrome A reveals topological and functional diversification among the plant photoreceptor isoforms. Nature plants (2023)
Xiang Feng, Gerrit J Schut, Dominik K Haja, Michael W W Adams, Huilin Li
Structure and electron transfer pathways of an electron-bifurcating NiFe-hydrogenase. Science advances 8 (8) (2022)
Fengwei Zheng, Roxana E Georgescu, Nina Y Yao, Huilin Li, Michael E O'Donnell
Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair. eLife 11 (2022)
Fengwei Zheng, Roxana E Georgescu, Nina Y Yao, Michael E O'Donnell, Huilin Li
DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp. Nature structural & molecular biology 29 (4) (2022)
Lance D Langston, Zuanning Yuan, Roxana E Georgescu, Huilin Li, Michael E O'Donnell
SV40 T-antigen uses a DNA shearing mechanism to initiate origin unwinding. Proceedings of the National Academy of Sciences of the United States of America 119 (49) (2022)
Xiansha Xiao, Xiang Feng, Jin Hee Yoo, Amanda Kovach, K Heran Darwin, Huilin Li
The β-Grasp Domain of Proteasomal ATPase Mpa Makes Critical Contacts with the Mycobacterium tuberculosis 20S Core Particle to Facilitate Degradation. mSphere 7 (5) (2022)
Hua Li, Wang-Sik Lee, Xiang Feng, Lin Bai, Benjamin C Jennings, Lin Liu, Balraj Doray, William M Canfield, Stuart Kornfeld, Huilin Li
Structure of the human GlcNAc-1-phosphotransferase αβ subunits reveals regulatory mechanism for lysosomal enzyme glycan phosphorylation. Nature structural & molecular biology 29 (4) (2022)
Hao-Chi Hsu, Michelle Wang, Amanda Kovach, Andrew J Darwin, Huilin Li
Pseudomonas aeruginosa C-Terminal Processing Protease CtpA Assembles into a Hexameric Structure That Requires Activation by a Spiral-Shaped Lipoprotein-Binding Partner. mBio (2022)
Hua Li, E Sethe Burgie, Zachary T K Gannam, Huilin Li, Richard David Vierstra
Plant phytochrome B is an asymmetric dimer with unique signalling potential. Nature 604 (7904) (2022)
Hongjun Yu, Dominik K Haja, Gerrit J Schut, Chang-Hao Wu, Xing Meng, Gongpu Zhao, Huilin Li, Michael W W Adams
Author Correction: Structure of the respiratory MBS complex reveals iron-sulfur cluster catalyzed sulfane sulfur reduction in ancient life. Nature communications 12 (1) (2021)
Peng Zhao, Chaoran Zhao, Dandan Chen, Caihong Yun, Huilin Li, Lin Bai
Structure and activation mechanism of the hexameric plasma membrane H+-ATPase. Nature communications 12 (1) (2021)
Lin Bai, Huilin Li
Cryo-EM structures of the endoplasmic reticulum membrane complex. The FEBS journal (2021)
Hao Zhang, Hao-Chi Hsu, Shoshanna C Kahne, Ryoma Hara, Wenhu Zhan, Xiuju Jiang, Kristin Burns-Huang, Tierra Ouellette, Toshihiro Imaeda, Rei Okamoto, Masanori Kawasaki, Mayako Michino, Tzu-Tshin Wong, Akinori Toita, Takafumi Yukawa, Francesca Moraca, Jeremie Vendome, Priya Saha, Kenjiro Sato, Kazuyoshi Aso, John Ginn, Peter T Meinke, Michael Foley, Carl F Nathan, K Heran Darwin, Huilin Li, Gang Lin
Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome. Journal of medicinal chemistry 64 (9) (2021)
Lin Bai, Bhawik Kumar Jain, Qinglong You, H Diessel Duan, Mehmet Takar, Todd R Graham, Huilin Li
Structural basis of the P4B ATPase lipid flippase activity. Nature communications 12 (1) (2021)
Huilin Li, Fengwei Zheng, Michael E O'Donnell
Water skating: How polymerase sliding clamps move on DNA. The FEBS journal (2021)
Xiang Feng, Gerrit J Schut, Gina L Lipscomb, Huilin Li, Michael W W Adams
Cryoelectron microscopy structure and mechanism of the membrane-associated electron-bifurcating flavoprotein Fix/EtfABCX. Proceedings of the National Academy of Sciences of the United States of America 118 (2) (2021)
Minge Du, Zuanning Yuan, Glenn T Werneburg, Nadine S Henderson, Hemil Chauhan, Amanda Kovach, Gongpu Zhao, Jessica Johl, Huilin Li, David G Thanassi
Processive dynamics of the usher assembly platform during uropathogenic Escherichia coli P pilus biogenesis. Nature communications 12 (1) (2021)
Xiang Feng, Yasunori Noguchi, Marta Barbon, Bruce Stillman, Christian Speck, Huilin Li
The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6. Nature communications 12 (1) (2021)
Heather O Bohl, Lin Bai, Huilin Li
Recent Progress in Structural Studies on the GT-C Superfamily of Protein Glycosyltransferases. Sub-cellular biochemistry 96 (2021)
Ye Tian, Julien R Lhermitte, Lin Bai, Thi Vo, Huolin L Xin, Huilin Li, Ruipeng Li, Masafumi Fukuto, Kevin G Yager, Jason S Kahn, Yan Xiong, Brian Minevich, Sanat K Kumar, Oleg Gang
Ordered three-dimensional nanomaterials using DNA-prescribed and valence-controlled material voxels. Nature materials 19 (7) (2020)
Y Hu, A Tareen, Y-J Sheu, W T Ireland, Christian Speck, Huilin Li, Leemor Joshua-Tor, Justin B Kinney, Bruce Stillman
Evolution of DNA replication origin specification and gene silencing mechanisms. Nature communications 11 (1) (2020)
Zuanning Yuan, Roxana Georgescu, Lin Bai, Dan Zhang, Huilin Li, Michael E O'Donnell
DNA unwinding mechanism of a eukaryotic replicative CMG helicase. Nature communications 11 (1) (2020)
Lin Bai, Qinglong You, Xiang Feng, Amanda Kovach, Huilin Li
Structure of the ER membrane complex, a transmembrane-domain insertase. Nature 584 (7821) (2020)
Zuanning Yuan, Roxana E Georgescu, Grant D Schauer, Michael E O'Donnell, Huilin Li
Structure of the polymerase ε holoenzyme and atomic model of the leading strand replisome. Nature communications 11 (1) (2020)
Lin Bai, Qinglong You, Bhawik Kumar Jain, H Diessel Duan, Amanda Kovach, Todd R Graham, Huilin Li
Transport mechanism of P4 ATPase phosphatidylcholine flippases. eLife 9 (2020)
Hongjun Yu, Dominik K Haja, Gerrit J Schut, Chang-Hao Wu, Xing Meng, Gongpu Zhao, Huilin Li, Michael W W Adams
Structure of the respiratory MBS complex reveals iron-sulfur cluster catalyzed sulfane sulfur reduction in ancient life. Nature communications 11 (1) (2020)
Fengwei Zheng, Roxana E Georgescu, Huilin Li, Michael E O'Donnell
Structure of eukaryotic DNA polymerase δ bound to the PCNA clamp while encircling DNA. Proceedings of the National Academy of Sciences of the United States of America 117 (48) (2020)
Zuanning Yuan, Sarah Schneider, Thomas Dodd, Alberto Riera, Lin Bai, Chunli Yan, Indiana Magdalou, Ivaylo Ivanov, Bruce Stillman, Huilin Li, Christian Speck
Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proceedings of the National Academy of Sciences of the United States of America 117 (30) (2020)
Lin Bai, Amanda Kovach, Qinglong You, Hao-Chi Hsu, Gongpu Zhao, Huilin Li
Autoinhibition and activation mechanisms of the eukaryotic lipid flippase Drs2p-Cdc50p. Nature communications 10 (1) (2019)
Zuanning Yuan, Roxana E Georgescu, Ruda de Luna Almeida Santos, Daniel Zhang, Lin Bai, Nina Y Yao, Gongpu Zhao, Michael E O'Donnell, Huilin Li
Ctf4 organizes sister replisomes and Pol α into a replication factory. eLife 8 (2019)
Huilin Li, Michael E O'Donnell
Mathematical description of eukaryotic chromosome replication. Proceedings of the National Academy of Sciences of the United States of America 116 (11) (2019)
Yuchen Zhou, Matthew W Elmes, Joseph M Sweeney, Olivia M Joseph, Joyce Che, Hao-Chi Hsu, Huilin Li, Dale G Deutsch, Iwao Ojima, Martin Kaczocha, Robert C Rizzo
Identification of Fatty Acid Binding Protein 5 Inhibitors Through Similarity-Based Screening. Biochemistry 58 (42) (2019)
Lin Bai, Amanda Kovach, Qinglong You, Alanna Kenny, Huilin Li
Structure of the eukaryotic protein O-mannosyltransferase Pmt1-Pmt2 complex. Nature structural & molecular biology 26 (8) (2019)
Wenhu Zhan, Hao-Chi Hsu, Trevor Morgan, Tierra Ouellette, Kristin Burns-Huang, Ryoma Hara, Adrian G Wright, Toshihiro Imaeda, Rei Okamoto, Kenjiro Sato, Mayako Michino, Manoj Ramjee, Kazuyoshi Aso, Peter T Meinke, Michael Foley, Carl F Nathan, Huilin Li, Gang Lin
Selective Phenylimidazole-Based Inhibitors of the Mycobacterium tuberculosis Proteasome. Journal of medicinal chemistry 62 (20) (2019)
Hongjun Yu, Tania J Lupoli, Amanda Kovach, Xing Meng, Gongpu Zhao, Carl F Nathan, Huilin Li
ATP hydrolysis-coupled peptide translocation mechanism of Mycobacterium tuberculosis ClpB. Proceedings of the National Academy of Sciences of the United States of America 115 (41) (2018)
Chengfeng Merriman, Huilin Li, Huilin Li, Dax Fu
Highly specific monoclonal antibodies for allosteric inhibition and immunodetection of the human pancreatic zinc transporter ZnT8. The Journal of biological chemistry 293 (42) (2018)
Michael E O'Donnell, Huilin Li
The ring-shaped hexameric helicases that function at DNA replication forks. Nature structural & molecular biology 25 (2) (2018)
Hao-Chi Hsu, Simon Tong, Yuchen Zhou, Matthew W Elmes, Su Yan, Martin Kaczocha, Dale G Deutsch, Robert C Rizzo, Iwao Ojima, Huilin Li
The Antinociceptive Agent SBFI-26 Binds to Anandamide Transporters FABP5 and FABP7 at Two Different Sites. Biochemistry 56 (27) (2017)
Yujie Wu, Kuan Hu, Defeng Li, Lin Bai, Shaoqing Yang, Jordan B Jastrab, Shuhao Xiao, Yonglin Hu, Susan Zhang, K Heran Darwin, Tao Wang, Huilin Li
Mycobacterium tuberculosis proteasomal ATPase Mpa has a β-grasp domain that hinders docking with the proteasome core protease. Molecular microbiology 105 (2) (2017)
Hao-Chi Hsu, Pradeep K Singh, Hao Fan, Rong Wang, George Sukenick, Carl Nathan, Gang Lin, Huilin Li
Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome. Biochemistry 56 (1) (2016)

Huilin Li.css-eqlu8i{font-size:small;padding-left:4px;} (H Li, Hua Li)

Publication Activity (10 Years)

Top Topics

Top Venues

Huilin Li (H Li, Hua Li)