Michael Ploug

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 39

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Journal of lipid research

The Journal of biological chemistry

Biomedicines

Rigshospitalet

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Rigshospitalet Mar 01 1997

Denmark

Group leader/dr.scient. :: Finsen Laboratory

Publications

Adrian Sutta, Nelia Nina Leemans, Michael Ploug, Anne Rosbjerg, Christian Del Agua Villa, Laura Pérez-Alós, Leon Cyranka, Adam S Vincek, Tomás de Garay, Keith D Rivera, Rafael Bayarri-Olmos
CL-11 circulates in serum as functionally distinct isoforms. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 38 (5) (2024)
Yan Q Chen, Ye Yang, Eugene Y Zhen, Thomas P Beyer, Hongxia Li, Yi Wen, Mariam Ehsani, Nicholas Jackson, Katherine Xie, Hyesoo Jung, Julia L Scheithauer, Anni Kumari, Gabriel Birrane, Anna M Russell, Deepa Balasubramaniam, Zhongping Liao, Robert W Siegel, Yuewei Qian, Michael Ploug, Stephen G Young, Robert J Konrad
Carboxyl-terminal sequences in APOA5 are important for suppressing ANGPTL3/8 activity. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Yan Q Chen, Ye Yang, Eugene Y Zhen, Thomas P Beyer, Hongxia Li, Yi Wen, Mariam Ehsani, Nicholas Jackson, Katherine Xie, Hyesoo Jung, Julia L Scheithauer, Anni Kumari, Gabriel Birrane, Anna M Russell, Deepa Balasubramaniam, Zhongping Liao, Robert W Siegel, Yuewei Qian, Michael Ploug, Stephen G Young, Robert J Konrad
Carboxyl-terminal sequences in APOA5 are important for suppressing ANGPTL3/8 activity. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Yan Q Chen, Ye Yang, Eugene Y Zhen, Thomas P Beyer, Hongxia Li, Yi Wen, Mariam Ehsani, Nicholas Jackson, Katherine Xie, Hyesoo Jung, Julia L Scheithauer, Anni Kumari, Gabriel Birrane, Anna M Russell, Deepa Balasubramaniam, Zhongping Liao, Robert W Siegel, Yuewei Qian, Michael Ploug, Stephen G Young, Robert J Konrad
Carboxyl-terminal sequences in APOA5 are important for suppressing ANGPTL3/8 activity. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Yan Q Chen, Ye Yang, Eugene Y Zhen, Thomas P Beyer, Hongxia Li, Yi Wen, Mariam Ehsani, Nicholas Jackson, Katherine Xie, Hyesoo Jung, Julia L Scheithauer, Anni Kumari, Gabriel Birrane, Anna M Russell, Deepa Balasubramaniam, Zhongping Liao, Robert W Siegel, Yuewei Qian, Michael Ploug, Stephen G Young, Robert J Konrad
Carboxyl-terminal sequences in APOA5 are important for suppressing ANGPTL3/8 activity. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Yan Q Chen, Ye Yang, Eugene Y Zhen, Thomas P Beyer, Hongxia Li, Yi Wen, Mariam Ehsani, Nicholas Jackson, Katherine Xie, Hyesoo Jung, Julia L Scheithauer, Anni Kumari, Gabriel Birrane, Anna M Russell, Deepa Balasubramaniam, Zhongping Liao, Robert W Siegel, Yuewei Qian, Michael Ploug, Stephen G Young, Robert J Konrad
Carboxyl-terminal sequences in APOA5 are important for suppressing ANGPTL3/8 activity. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Anni Kumari, Anne Louise Grønnemose, Kristian K Kristensen, Anne-Marie Lund Winther, Stephen G Young, Thomas J D Jørgensen, Michael Ploug
Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Anni Kumari, Anne Louise Grønnemose, Kristian K Kristensen, Anne-Marie Lund Winther, Stephen G Young, Thomas J D Jørgensen, Michael Ploug
Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Anni Kumari, Anne Louise Grønnemose, Kristian K Kristensen, Anne-Marie Lund Winther, Stephen G Young, Thomas J D Jørgensen, Michael Ploug
Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Wenxin Song, Ye Yang, Patrick Heizer, Yiping Tu, Thomas A Weston, Joonyoung R Kim, Priscilla Munguia, Hyesoo Jung, Jared L-C Fong, Caitlyn Tran, Michael Ploug, Anne P Beigneux, Stephen G Young, Loren G Fong
Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Anni Kumari, Anne Louise Grønnemose, Kristian K Kristensen, Anne-Marie Lund Winther, Stephen G Young, Thomas J D Jørgensen, Michael Ploug
Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Wenxin Song, Ye Yang, Patrick Heizer, Yiping Tu, Thomas A Weston, Joonyoung R Kim, Priscilla Munguia, Hyesoo Jung, Jared L-C Fong, Caitlyn Tran, Michael Ploug, Anne P Beigneux, Stephen G Young, Loren G Fong
Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Wenxin Song, Ye Yang, Patrick Heizer, Yiping Tu, Thomas A Weston, Joonyoung R Kim, Priscilla Munguia, Hyesoo Jung, Jared L-C Fong, Caitlyn Tran, Michael Ploug, Anne P Beigneux, Stephen G Young, Loren G Fong
Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Anni Kumari, Anne Louise Grønnemose, Kristian K Kristensen, Anne-Marie Lund Winther, Stephen G Young, Thomas J D Jørgensen, Michael Ploug
Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Anni Kumari, Anne Louise Grønnemose, Kristian K Kristensen, Anne-Marie Lund Winther, Stephen G Young, Thomas J D Jørgensen, Michael Ploug
Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Wenxin Song, Ye Yang, Patrick Heizer, Yiping Tu, Thomas A Weston, Joonyoung R Kim, Priscilla Munguia, Hyesoo Jung, Jared L-C Fong, Caitlyn Tran, Michael Ploug, Anne P Beigneux, Stephen G Young, Loren G Fong
Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Wenxin Song, Ye Yang, Patrick Heizer, Yiping Tu, Thomas A Weston, Joonyoung R Kim, Priscilla Munguia, Hyesoo Jung, Jared L-C Fong, Caitlyn Tran, Michael Ploug, Anne P Beigneux, Stephen G Young, Loren G Fong
Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Wenxin Song, Ye Yang, Patrick Heizer, Yiping Tu, Thomas A Weston, Joonyoung R Kim, Priscilla Munguia, Hyesoo Jung, Jared L-C Fong, Caitlyn Tran, Michael Ploug, Anne P Beigneux, Stephen G Young, Loren G Fong
Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Wenxin Song, Anne P Beigneux, Thomas A Weston, Kai Chen, Ye Yang, Le Phuong Nguyen, Paul Guagliardo, Hyesoo Jung, Anh P Tran, Yiping Tu, Caitlyn Tran, Gabriel Birrane, Kazuya Miyashita, Katsuyuki Nakajima, Masami Murakami, Peter Tontonoz, Haibo Jiang, Michael Ploug, Loren G Fong, Stephen G Young
The lipoprotein lipase that is shuttled into capillaries by GPIHBP1 enters the glycocalyx where it mediates lipoprotein processing. Proceedings of the National Academy of Sciences of the United States of America 120 (44) (2023)
Anni Kumari, Anne Louise Grønnemose, Kristian K Kristensen, Anne-Marie Lund Winther, Stephen G Young, Thomas J D Jørgensen, Michael Ploug
Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Wenxin Song, Ye Yang, Patrick Heizer, Yiping Tu, Thomas A Weston, Joonyoung R Kim, Priscilla Munguia, Hyesoo Jung, Jared L-C Fong, Caitlyn Tran, Michael Ploug, Anne P Beigneux, Stephen G Young, Loren G Fong
Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Stephen G Young, Wenxin Song, Ye Yang, Gabriel Birrane, Haibo Jiang, Anne P Beigneux, Michael Ploug, Loren G Fong
A protein of capillary endothelial cells, GPIHBP1, is crucial for plasma triglyceride metabolism. Proceedings of the National Academy of Sciences of the United States of America 119 (36) (2022)
Anni Kumari, Kristian K Kristensen, Michael Ploug, Anne-Marie Lund Winther
The Importance of Lipoprotein Lipase Regulation in Atherosclerosis. Biomedicines 9 (7) (2021)
Virginia Metrangolo, Michael Ploug, Lars H Engelholm
The Urokinase Receptor (uPAR) as a "Trojan Horse" in Targeted Cancer Therapy: Challenges and Opportunities. Cancers 13 (21) (2021)
Katrine Z Leth-Espensen, Kristian K Kristensen, Anni Kumari, Anne-Marie Lund Winther, Stephen G Young, Thomas J D Jørgensen, Michael Ploug
The intrinsic instability of the hydrolase domain of lipoprotein lipase facilitates its inactivation by ANGPTL4-catalyzed unfolding. Proceedings of the National Academy of Sciences of the United States of America 118 (12) (2021)
John G Luz, Anne P Beigneux, DeeAnn K Asamoto, Cuiwen He, Wenxin Song, Christopher M Allan, Jazmin Morales, Yiping Tu, Adam Kwok, Thomas Cottle, Muthuraman Meiyappan, Loren G Fong, Judy E Kim, Michael Ploug, Stephen G Young, Gabriel Birrane
The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase. Journal of lipid research 61 (10) (2020)
Kristian K Kristensen, Katrine Zinck Leth-Espensen, Haydyn D T Mertens, Gabriel Birrane, Muthuraman Meiyappan, Gunilla Olivecrona, Thomas J D Jørgensen, Stephen G Young, Michael Ploug
Unfolding of monomeric lipoprotein lipase by ANGPTL4: Insight into the regulation of plasma triglyceride metabolism. Proceedings of the National Academy of Sciences of the United States of America 117 (8) (2020)
Kristian Kølby Kristensen, Katrine Zinck Leth-Espensen, Stephen G Young, Michael Ploug
ANGPTL4 inactivates lipoprotein lipase by catalyzing the irreversible unfolding of LPL's hydrolase domain. Journal of lipid research 61 (9) (2020)
Jens Lutz, Malgorzata Dunaj-Kazmierowska, Sven Arcan, Ursula Kassner, Kazuya Miyashita, Masami Murakami, Michael Ploug, Loren G Fong, Stephen G Young, Katsuyuki Nakajima, Anne P Beigneux
Chylomicronemia From GPIHBP1 Autoantibodies Successfully Treated With Rituximab: A Case Report. Annals of internal medicine 173 (9) (2020)
David Xu, Khuchtumur Bum-Erdene, Julie M Leth, Mona K Ghozayel, Michael Ploug, Samy O Meroueh
Small-Molecule Inhibition of the uPAR ⋅ uPA Interaction by Conformational Selection. ChemMedChem 16 (2) (2020)
Warner Alpízar-Alpízar, Mette E Skindersoe, Lone Rasmussen, Mette C Kriegbaum, Ib J Christensen, Ida K Lund, Martin Illemann, Ole D Laerum, Karen Angeliki Krogfelt, Leif P Andersen, Michael Ploug
Helicobacter pylori Colonization Drives Urokinase Receptor (uPAR) Expression in Murine Gastric Epithelium During Early Pathogenesis. Microorganisms 8 (7) (2020)
Kazuya Miyashita, Jens Lutz, Lisa C Hudgins, Dana Toib, Ambika P Ashraf, Wenxin Song, Masami Murakami, Katsuyuki Nakajima, Michael Ploug, Loren G Fong, Stephen G Young, Anne P Beigneux
Chylomicronemia from GPIHBP1 autoantibodies. Journal of lipid research 61 (11) (2020)
Julie Maja Leth, Katrine Zinck Leth-Espensen, Kristian Kølby Kristensen, Anni Kumari, Anne-Marie Lund Winther, Stephen G Young, Michael Ploug
Evolution and Medical Significance of LU Domain-Containing Proteins. International journal of molecular sciences 20 (11) (2019)
Julie M Leth, Haydyn D T Mertens, Katrine Zinck Leth-Espensen, Thomas J D Jørgensen, Michael Ploug
Did evolution create a flexible ligand-binding cavity in the urokinase receptor through deletion of a plesiotypic disulfide bond? The Journal of biological chemistry 294 (18) (2019)
Anne P Beigneux, Christopher M Allan, Norma P Sandoval, Geoffrey W Cho, Patrick J Heizer, Rachel S Jung, Kimber L Stanhope, Peter J Havel, Gabriel Birrane, Muthuraman Meiyappan, John E Gill, Masami Murakami, Kazuya Miyashita, Katsuyuki Nakajima, Michael Ploug, Loren G Fong, Stephen G Young
Lipoprotein lipase is active as a monomer. Proceedings of the National Academy of Sciences of the United States of America 116 (13) (2019)
Min Liu, Lin Lin, Gunilla Høyer-Hansen, Michael Ploug, Hanlin Li, Longguang X Jiang, Cai Yuan, Jinyu Li, Mingdong Huang
Crystal structure of the unoccupied murine urokinase-type plasminogen activator receptor (uPAR) reveals a tightly packed DII-DIII unit. FEBS letters 593 (11) (2019)
Gabriel Birrane, Anne P Beigneux, Brian Dwyer, Bettina Strack-Logue, Kristian Kølby Kristensen, Omar L Francone, Loren G Fong, Haydyn D T Mertens, Clark Q Pan, Michael Ploug, Stephen G Young, Muthuraman Meiyappan
Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis. Proceedings of the National Academy of Sciences of the United States of America 116 (5) (2018)
Kristian K Kristensen, Søren Roi Midtgaard, Simon Mysling, Oleg Kovrov, Lars Bo Hansen, Nicholas Skar-Gislinge, Anne P Beigneux, Birthe B Kragelund, Gunilla Olivecrona, Stephen G Young, Thomas J D Jørgensen, Loren G Fong, Michael Ploug
A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase. Proceedings of the National Academy of Sciences of the United States of America 115 (26) (2018)
Simon Mysling, Kristian Kølby Kristensen, Mikael Larsson, Oleg Kovrov, André Bensadouen, Thomas Jd Jørgensen, Gunilla Olivecrona, Stephen G Young, Michael Ploug
The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding. eLife 5 (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Michael Ploug