Samy O Meroueh

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 15

Top Venues

ChemMedChem

Journal of medicinal chemistry

Biochemistry

ACS chemical biology

Indiana University School of Medicine

Wayne State University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Indiana University School of Medicine

United States

Associate Professor :: Biochemistry and Molecular Biology

University of Notre Dame

United States

Postdoctoral Fellow :: Chemistry and Biochemistry

Wayne State University

United States

Postdoctoral Associate :: Chemistry

Education History

Wayne State University

United States

PHD :: Chemistry

Publications

Robert J Brenner, Alexander D Landgraf, Khuchtumur Bum-Erdene, Giovanni Gonzalez-Gutierrez, Samy O Meroueh
Crystal Packing Reveals a Potential Autoinhibited KRAS Dimer Interface and a Strategy for Small-Molecule Inhibition of RAS Signaling. Biochemistry (2023)
Khuchtumur Bum-Erdene, Mona K Ghozayel, Mark J Zhang, Giovanni Gonzalez-Gutierrez, Samy O Meroueh
Chloroacetamide fragment library screening identifies new scaffolds for covalent inhibition of the TEAD·YAP1 interaction. RSC medicinal chemistry 14 (9) (2023)
Muhammad S Hussain, Degang Liu, Warren J Alilain, Samy O Meroueh
Covalent Fragment Inhibits RhoA Activation by Guanine Exchange Factors. ACS chemical neuroscience (2023)
Khuchtumur Bum-Erdene, I-Ju Yeh, Giovanni Gonzalez-Gutierrez, Mona K Ghozayel, Karen Pollok, Samy O Meroueh
Small-Molecule Cyanamide Pan-TEAD·YAP1 Covalent Antagonists. Journal of medicinal chemistry 66 (1) (2022)
Khuchtumur Bum-Erdene, I-Ju Yeh, Giovanni Gonzalez-Gutierrez, Mona K Ghozayel, Karen Pollok, Samy O Meroueh
Small-Molecule Cyanamide Pan-TEAD·YAP1 Covalent Antagonists. Journal of medicinal chemistry 66 (1) (2022)
Khuchtumur Bum-Erdene, Mona K Ghozayel, David Xu, Samy O Meroueh
Covalent Fragment Screening Identifies Rgl2 RalGEF Cysteine for Targeted Covalent Inhibition of Ral GTPase Activation. ChemMedChem 17 (6) (2022)
Khuchtumur Bum-Erdene, I-Ju Yeh, Giovanni Gonzalez-Gutierrez, Mona K Ghozayel, Karen Pollok, Samy O Meroueh
Small-Molecule Cyanamide Pan-TEAD·YAP1 Covalent Antagonists. Journal of medicinal chemistry (2022)
Khuchtumur Bum-Erdene, I-Ju Yeh, Giovanni Gonzalez-Gutierrez, Mona K Ghozayel, Karen Pollok, Samy O Meroueh
Small-Molecule Cyanamide Pan-TEAD·YAP1 Covalent Antagonists. Journal of medicinal chemistry 66 (1) (2022)
David Xu, Donghui Zhou, Khuchtumur Bum-Erdene, Barbara J Bailey, Kamakshi Sishtla, Sheng Liu, Jun Wan, Uma K Aryal, Jonathan A Lee, Clark D Wells, Melissa L Fishel, Timothy W Corson, Karen E Pollok, Samy O Meroueh
Phenotypic Screening of Chemical Libraries Enriched by Molecular Docking to Multiple Targets Selected from Glioblastoma Genomic Data. ACS chemical biology 15 (6) (2020)
David Xu, Khuchtumur Bum-Erdene, Julie M Leth, Mona K Ghozayel, Michael Ploug, Samy O Meroueh
Small-Molecule Inhibition of the uPAR ⋅ uPA Interaction by Conformational Selection. ChemMedChem 16 (2) (2020)
Yubing Si, David Xu, Khuchtumur Bum-Erdene, Mona K Ghozayel, Baocheng Yang, Paul A Clemons, Samy O Meroueh
Chemical Space Overlap with Critical Protein-Protein Interface Residues in Commercial and Specialized Small-Molecule Libraries. ChemMedChem 14 (1) (2018)
David Xu, Liwei Li, Donghui Zhou, Degang Liu, Andy Hudmon, Samy O Meroueh
Structure-Based Target-Specific Screening Leads to Small-Molecule CaMKII Inhibitors. ChemMedChem 12 (9) (2017)
David Xu, Yubing Si, Samy O Meroueh
A Computational Investigation of Small-Molecule Engagement of Hot Spots at Protein-Protein Interaction Interfaces. Journal of chemical information and modeling 57 (9) (2017)
Degang Liu, David Xu, Min Liu, William Eric Knabe, Cai Yuan, Donghui Zhou, Ming-Dong Huang, Samy O Meroueh
Small Molecules Engage Hot Spots through Cooperative Binding To Inhibit a Tight Protein-Protein Interaction. Biochemistry 56 (12) (2017)
David Xu, Khuchtumur Bum-Erdene, Yubing Si, Donghui Zhou, Mona K Ghozayel, Samy O Meroueh
Mimicking Intermolecular Interactions of Tight Protein-Protein Complexes for Small-Molecule Antagonists. ChemMedChem 12 (21) (2017)

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Publication Activity (10 Years)

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Samy O Meroueh