Michael Popiolek

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 10

Top Venues

ACS chemical neuroscience

Journal of medicinal chemistry

Biochemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Christopher R Butter, Michael Popiolek, Laura A McAllister, Erik A LaChapelle, Melissa Kramer, Elizabeth M Beck, Scot Mente, Michael A Brodney, Matthew Brown, Adam M Gilbert, Chris Helal, Kevin Ogilvie, Jeremy Starr, Daniel Uccello, Sarah Grimwood, Jeremy Edgerton, Jonathan Garst-Orozco, Rouba Kozak, Susan Lotarski, Amie Rossi, Deborah Smith, Rebecca O'Connor, John Lazzaro, Claire Steppan, Stefanus J Steyn
Design and Synthesis of Clinical Candidate PF-06852231 (CVL-231): A Brain Penetrant, Selective, Positive Allosteric Modulator of the M 4 Muscarinic Acetylcholine Receptor. Journal of medicinal chemistry 67 (13) (2024)
Christopher R Butter, Michael Popiolek, Laura A McAllister, Erik A LaChapelle, Melissa Kramer, Elizabeth M Beck, Scot Mente, Michael A Brodney, Matthew Brown, Adam M Gilbert, Chris Helal, Kevin Ogilvie, Jeremy Starr, Daniel Uccello, Sarah Grimwood, Jeremy Edgerton, Jonathan Garst-Orozco, Rouba Kozak, Susan Lotarski, Amie Rossi, Deborah Smith, Rebecca O'Connor, John Lazzaro, Claire Steppan, Stefanus J Steyn
Design and Synthesis of Clinical Candidate PF-06852231 (CVL-231): A Brain Penetrant, Selective, Positive Allosteric Modulator of the M 4 Muscarinic Acetylcholine Receptor. Journal of medicinal chemistry 67 (13) (2024)
Christopher R Butter, Michael Popiolek, Laura A McAllister, Erik A LaChapelle, Melissa Kramer, Elizabeth M Beck, Scot Mente, Michael A Brodney, Matthew Brown, Adam M Gilbert, Chris Helal, Kevin Ogilvie, Jeremy Starr, Daniel Uccello, Sarah Grimwood, Jeremy Edgerton, Jonathan Garst-Orozko, Rouba Kozak, Susan Lotarski, Amie Rossi, Deborah Smith, Rebecca O'Connor, John Lazzaro, Claire Steppan, Stefanus J Steyn
Design and Synthesis of Clinical Candidate PF-06852231 (CVL-231): A Brain Penetrant, Selective, Positive Allosteric Modulator of the M 4 Muscarinic Acetylcholine Receptor. Journal of medicinal chemistry (2024)
Damon Young, Michael Popiolek, Patrick Trapa, Kari R Fonseca, Julie Brevard, David L Gray, Rouba Kozak
D1 Agonist Improved Movement of Parkinsonian Nonhuman Primates with Limited Dyskinesia Side Effects. ACS chemical neuroscience 11 (4) (2020)
Catherine A Thorn, Joshua Moon, Clinton A Bourbonais, John Harms, Jeremy R Edgerton, Eda Stark, Stefanus J Steyn, Christopher R Butter, John T Lazzaro, Rebecca E O'Connor, Michael Popiolek
Striatal, Hippocampal, and Cortical Networks Are Differentially Responsive to the M4- and M1-Muscarinic Acetylcholine Receptor Mediated Effects of Xanomeline. ACS chemical neuroscience 10 (8) (2019)
Catherine A Thorn, Joshua Moon, Clinton A Bourbonais, John Harms, Jeremy R Edgerton, Eda Stark, Stefanus J Steyn, Christopher R Butter, John T Lazzaro, Rebecca E O'Connor, Michael Popiolek
Striatal, Hippocampal, and Cortical Networks Are Differentially Responsive to the M4- and M1-Muscarinic Acetylcholine Receptor Mediated Effects of Xanomeline. ACS chemical neuroscience 10 (3) (2018)
Michael Popiolek, Yael Mandelblat-Cerf, Damon Young, Jonathan Garst-Orozco, Susan M Lotarski, Eda Stark, Melissa Kramer, Christopher R Butter, Rouba Kozak
In Vivo Modulation of Hippocampal Excitability by M4 Muscarinic Acetylcholine Receptor Activator: Implications for Treatment of Alzheimer's Disease and Schizophrenic Patients. ACS chemical neuroscience 10 (3) (2018)
Michael Popiolek, Brendan Tierney, Stefanus J Steyn, Michael DeVivo
Lack of Effect of Sodium Benzoate at Reported Clinical Therapeutic Concentration on d-Alanine Metabolism in Dogs. ACS chemical neuroscience 9 (11) (2018)
Jennifer E Davoren, Michelle Garnsey, Betty Pettersen, Michael A Brodney, Jeremy R Edgerton, Jean-Philippe Fortin, Sarah Grimwood, Anthony R Harris, Stephen Jenkinson, Terry Kenakin, John T Lazzaro, Che-Wah Lee, Susan M Lotarski, Lisa Nottebaum, Steven V O'Neil, Michael Popiolek, Simeon Ramsey, Stefanus J Steyn, Catherine A Thorn, Lei Zhang, Damien Webb
Design and Synthesis of γ- and δ-Lactam M1 Positive Allosteric Modulators (PAMs): Convulsion and Cholinergic Toxicity of an M1-Selective PAM with Weak Agonist Activity. Journal of medicinal chemistry 60 (15) (2017)
Michael Popiolek, David P Nguyen, Veronica Reinhart, Jeremy R Edgerton, John Harms, Susan M Lotarski, Stefanus J Steyn, Jennifer E Davoren, Sarah Grimwood
Inositol Phosphate Accumulation in Vivo Provides a Measure of Muscarinic M1 Receptor Activation. Biochemistry 55 (51) (2016)

Michael Popiolek.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Michael Popiolek