Michael S Wolfe

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 21

Top Venues

Communications biology

Neural regeneration research

Journal of the American Chemical Society

Biochemistry

University of Kansas

University of Kansas (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Kansas

United States

Mathias P. Mertes Professor :: Medicinal Chemistry

Brigham and Women's Hospital

United States

Associate/Full Professor :: Neurology

University of Tennessee Health Science Center College of Pharmacy Memphis

United States

Assistant/Associate Professor :: Pharmaceutical Sciences

National Institutes of Health

United States

Pharmacology Research Associate Trainee :: Laboratory of Cell Biology NIMH

University of Kansas

United States

Postdoctoral Fellow :: Medicinal Chemistry

Education History

University of Kansas

United States

PHD :: Medicinal Chemistry

University of the Sciences in Philadelphia

United States

BSC :: Chemistry

Publications

Parnian Arafi, Sujan Devkota, Maesako Masato, Michael S Wolfe
Alzheimer-mutant γ-secretase complexes stall amyloid β-peptide production. bioRxiv : the preprint server for biology (2024)
Yinglong Miao, Michael S Wolfe
Emerging structures and dynamic mechanisms of γ-secretase for Alzheimer's disease. Neural regeneration research 20 (1) (2024)
Yinglong Miao, Michael S Wolfe
Emerging structures and dynamic mechanisms of γ-secretase for Alzheimer's disease. Neural regeneration research 20 (1) (2024)
Yinglong Miao, Michael S Wolfe
Emerging structures and dynamic mechanisms of γ-secretase for Alzheimer's disease. Neural regeneration research 20 (1) (2024)
Hung Nguyen Do, Sujan Devkota, Apurba Bhattarai, Michael S Wolfe, Yinglong Miao
Effects of presenilin-1 familial Alzheimer's disease mutations on γ-secretase activation for cleavage of amyloid precursor protein. Communications biology 6 (1) (2023)
Hung Nguyen Do, Sujan Devkota, Apurba Bhattarai, Michael S Wolfe, Yinglong Miao
Effects of presenilin-1 familial Alzheimer's disease mutations on γ-secretase activation for cleavage of amyloid precursor protein. Communications biology 6 (1) (2023)
Hung Nguyen Do, Shweta R Malvankar, Michael S Wolfe, Yinglong Miao
Molecular Dynamics Activation of γ-Secretase for Cleavage of the Notch1 Substrate. ACS chemical neuroscience (2023)
Hung Nguyen Do, Sujan Devkota, Apurba Bhattarai, Michael S Wolfe, Yinglong Miao
Effects of presenilin-1 familial Alzheimer's disease mutations on γ-secretase activation for cleavage of amyloid precursor protein. Communications biology 6 (1) (2023)
Hung Nguyen Do, Sujan Devkota, Apurba Bhattarai, Michael S Wolfe, Yinglong Miao
Effects of presenilin-1 familial Alzheimer's disease mutations on γ-secretase activation for cleavage of amyloid precursor protein. Communications biology 6 (1) (2023)
Liviu Aron, Chenxi Qiu, Zhen Kai Ngian, Marianna Liang, Derek Drake, Jaejoon Choi, Marty A Fernandez, Perle Roche, Emma L Bunting, Ella K Lacey, Sara E Hamplova, Monlan Yuan, Michael S Wolfe, David A Bennett, Eunjung A Lee, Bruce A Yankner
A neurodegeneration checkpoint mediated by REST protects against the onset of Alzheimer's disease. Nature communications 14 (1) (2023)
Hung Nguyen Do, Sujan Devkota, Apurba Bhattarai, Michael S Wolfe, Yinglong Miao
Effects of presenilin-1 familial Alzheimer's disease mutations on γ-secretase activation for cleavage of amyloid precursor protein. Communications biology 6 (1) (2023)
Michael S Wolfe
γ-Secretase as a drug target for familial Alzheimer's disease: the road less traveled. Future medicinal chemistry 14 (19) (2022)
Alec K McKendell, Mei C Q Houser, Shane P C Mitchell, Michael S Wolfe, Oksana Berezovska, Maesako Masato
In-Depth Characterization of Endo-Lysosomal Aβ in Intact Neurons. Biosensors 12 (8) (2022)
Apurba Bhattarai, Sujan Devkota, Hung Nguyen Do, Jinan Wang, Sanjay Bhattarai, Michael S Wolfe, Yinglong Miao
Mechanism of Tripeptide Trimming of Amyloid β-Peptide 49 by γ-Secretase. Journal of the American Chemical Society 144 (14) (2022)
Apurba Bhattarai, Sujan Devkota, Hung Nguyen Do, Jinan Wang, Sanjay Bhattarai, Michael S Wolfe, Yinglong Miao
Correction to "Mechanism of Tripeptide Trimming of Amyloid β-Peptide 49 by γ-Secretase". Journal of the American Chemical Society 144 (20) (2022)
Sanjay Bhattarai, Sujan Devkota, Michael S Wolfe
Design of Transmembrane Mimetic Structural Probes to Trap Different Stages of γ-Secretase-Substrate Interaction. Journal of medicinal chemistry 64 (20) (2021)
Masato Maesako, Mei Cq Houser, Yuliia Turchyna, Michael S Wolfe, Oksana Berezovska
Presenilin/γ-secretase activity is located in acidic compartments of live neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience (2021)
Michael S Wolfe
Probing Mechanisms and Therapeutic Potential of γ-Secretase in Alzheimer's Disease. Molecules (Basel, Switzerland) 26 (2) (2021)
Sanjay Bhattarai, Sujan Devkota, Kathleen M Meneely, Minli Xing, Justin T Douglas, Michael S Wolfe
Design of Substrate Transmembrane Mimetics as Structural Probes for γ-Secretase. Journal of the American Chemical Society 142 (7) (2020)
Anijamol T Philip, Sujan Devkota, Shweta Malvankar, Sanjay Bhattarai, Kathleen M Meneely, Todd D Williams, Michael S Wolfe
Designed Helical Peptides as Functional Probes for γ-Secretase. Biochemistry 58 (44) (2019)
Michael S Wolfe
Structure and Function of the γ-Secretase Complex. Biochemistry 58 (27) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Michael S Wolfe