Milton Packer (M Packer)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 103

Top Venues

European heart journal

Circulation

Journal of the American Heart Association

Diabetes, obesity & metabolism

This page only lists publications with an associated author ORCID identifier.

Publications

Javed Butler, Norman Stockbridge, Milton Packer
Win Ratio: A Seductive But Potentially Misleading Method for Evaluating Evidence from Clinical Trials. Circulation 149 (20) (2024)
Milton Packer
Dual SGLT1 and SGLT2 inhibitor sotagliflozin achieves FDA approval: landmark or landmine? Nature cardiovascular research 2 (8) (2024)
Milton Packer
Traditional Chinese medicine: cardiovascular drug development through a holistic framework. European heart journal (2024)
Milton Packer
Left Ventricular Ejection Fraction in Heart Failure: Crazy, Stupid Love-and Maybe, Redemption. Journal of the American Heart Association 13 (8) (2024)
Pooja Dewan, Li Shen, João Pedro Ferreira, Pardeep S Jhund, Inder S Anand, Alvin Chandra, Lu-May Chiang, Brian Lee Claggett, Akshay S Desai, Jianjian Gong, Carolyn Su Ping Lam, Martin P Lefkowitz, Aldo Pietro Maggioni, Felipe A Martinez, Milton Packer, Margaret M Redfield, Jean-Lucien Rouleau, Dirk J van Veldhuisen, Faiez Zannad, Michael R Zile, Scott D Solomon, John J V McMurray
Effect of Sacubitril/Valsartan on Cognitive Function in Patients With Heart Failure With Preserved Ejection Fraction: A Prespecified Analysis of PARAGON-HF. Circulation 150 (4) (2024)
Natasha L Patel-Murray, Luqing Zhang, Brian Lee Claggett, Dongchu Xu, Pablo Serrano-Fernandez, Margaret L Healey, Simon Wandel, Chien-Wei Chen, Jaison Jacob, Huilei Xu, Gordon M Turner, William Chutkow, Denise P Yates, Christopher J O'Donnell, Margaret F Prescott, Martin P Lefkowitz, Claudio R Gimpelewicz, Michael T Beste, Faye Zhao, Liangke Gou, Akshay S Desai, Pardeep S Jhund, Milton Packer, Marc A Pfeffer, Margaret M Redfield, Jean-Lucien Rouleau, Faiez Zannad, Michael R Zile, John Joseph Valentine McMurray, Michael M Mendelson, Scott D Solomon, Jonathan W Cunningham
Aptamer Proteomics for Biomarker Discovery in Heart Failure With Preserved Ejection Fraction: The PARAGON-HF Proteomic Substudy. Journal of the American Heart Association 13 (13) (2024)
Natasha L Patel-Murray, Luqing Zhang, Brian Lee Claggett, Dongchu Xu, Pablo Serrano-Fernandez, Margaret L Healey, Simon Wandel, Chien-Wei Chen, Jaison Jacob, Huilei Xu, Gordon M Turner, William Chutkow, Denise P Yates, Christopher J O'Donnell, Margaret F Prescott, Martin P Lefkowitz, Claudio R Gimpelewicz, Michael T Beste, Faye Zhao, Liangke Gou, Akshay S Desai, Pardeep S Jhund, Milton Packer, Marc A Pfeffer, Margaret M Redfield, Jean-Lucien Rouleau, Faiez Zannad, Michael R Zile, John Joseph Valentine McMurray, Michael M Mendelson, Scott D Solomon, Jonathan W Cunningham
Aptamer Proteomics for Biomarker Discovery in Heart Failure With Preserved Ejection Fraction: The PARAGON-HF Proteomic Substudy. Journal of the American Heart Association 13 (13) (2024)
Milton Packer, Stefan D Anker, Javed Butler, John G F Cleland, Paul R Kalra, Robert J Mentz, Piotr Ponikowski
Identification of three mechanistic pathways for iron-deficient heart failure. European heart journal 45 (26) (2024)
Natasha L Patel-Murray, Luqing Zhang, Brian Lee Claggett, Dongchu Xu, Pablo Serrano-Fernandez, Margaret L Healey, Simon Wandel, Chien-Wei Chen, Jaison Jacob, Huilei Xu, Gordon M Turner, William Chutkow, Denise P Yates, Christopher J O'Donnell, Margaret F Prescott, Martin P Lefkowitz, Claudio R Gimpelewicz, Michael T Beste, Faye Zhao, Liangke Gou, Akshay S Desai, Pardeep S Jhund, Milton Packer, Marc A Pfeffer, Margaret M Redfield, Jean-Lucien Rouleau, Faiez Zannad, Michael R Zile, John Joseph Valentine McMurray, Michael M Mendelson, Scott D Solomon, Jonathan W Cunningham
Aptamer Proteomics for Biomarker Discovery in Heart Failure With Preserved Ejection Fraction: The PARAGON-HF Proteomic Substudy. Journal of the American Heart Association 13 (13) (2024)
Siddharth M Patel, Yu Mi Kang, KyungAh Im, Brendon L Neuen, Stefan D Anker, Deepak L Bhatt, Javed Butler, David Z I Cherney, Brian Lee Claggett, Robert A Fletcher, William G Herrington, Catherine M Viscoli, Meg J Jardine, Kenneth W Mahaffey, Darren K McGuire, John Joseph Valentine McMurray, Bruce C Neal, Milton Packer, Vlado Perkovic, Scott D Solomon, Natalie Staplin, Muthiah Vaduganathan, Christoph Wanner, David Collins Wheeler, Faiez Zannad, Yujie Zhao, Hiddo J Lambers Heerspink, Marc S Sabatine, Stephen D Wiviott
Sodium-Glucose Cotransporter-2 Inhibitors and Major Adverse Cardiovascular Outcomes: A SMART-C Collaborative Meta-Analysis. Circulation 149 (23) (2024)
Siddharth M Patel, Yu Mi Kang, KyungAh Im, Brendon L Neuen, Stefan D Anker, Deepak L Bhatt, Javed Butler, David Z I Cherney, Brian Lee Claggett, Robert A Fletcher, William G Herrington, Catherine M Viscoli, Meg J Jardine, Kenneth W Mahaffey, Darren K McGuire, John Joseph Valentine McMurray, Bruce C Neal, Milton Packer, Vlado Perkovic, Scott D Solomon, Natalie Staplin, Muthiah Vaduganathan, Christoph Wanner, David Collins Wheeler, Faiez Zannad, Yujie Zhao, Hiddo J Lambers Heerspink, Marc S Sabatine, Stephen D Wiviott
Sodium Glucose Co-transporter 2 Inhibitors and Major Adverse Cardiovascular Outcomes: A SMART-C Collaborative Meta-Analysis. Circulation (2024)
Milton Packer, Stefan D Anker, Javed Butler, John G F Cleland, Paul R Kalra, Robert J Mentz, Piotr Ponikowski
Identification of three mechanistic pathways for iron-deficient heart failure. European heart journal 45 (26) (2024)
Milton Packer, Stefan D Anker, Javed Butler, John G F Cleland, Paul R Kalra, Robert J Mentz, Piotr Ponikowski, Khawaja M Talha
Redefining Iron Deficiency in Patients With Chronic Heart Failure. Circulation 150 (2) (2024)
Milton Packer, Stefan D Anker, Javed Butler, John G F Cleland, Paul R Kalra, Robert J Mentz, Piotr Ponikowski, Khawaja M Talha
Redefining Iron Deficiency in Patients With Chronic Heart Failure. Circulation (2024)
Pooja Dewan, Li Shen, João Pedro Ferreira, Pardeep S Jhund, Inder S Anand, Alvin Chandra, Lu-May Chiang, Brian Lee Claggett, Akshay S Desai, Jianjian Gong, Carolyn Su Ping Lam, Martin P Lefkowitz, Aldo Pietro Maggioni, Felipe A Martinez, Milton Packer, Margaret M Redfield, Jean-Lucien Rouleau, Dirk J van Veldhuisen, Faiez Zannad, Michael R Zile, Scott D Solomon, John J V McMurray
Effect of Sacubitril/Valsartan on Cognitive Function in Patients With Heart Failure With Preserved Ejection Fraction: A Prespecified Analysis of PARAGON-HF. Circulation (2024)
Siddharth M Patel, Yu Mi Kang, KyungAh Im, Brendon L Neuen, Stefan D Anker, Deepak L Bhatt, Javed Butler, David Z I Cherney, Brian Lee Claggett, Robert A Fletcher, William G Herrington, Catherine M Viscoli, Meg J Jardine, Kenneth W Mahaffey, Darren K McGuire, John Joseph Valentine McMurray, Bruce C Neal, Milton Packer, Vlado Perkovic, Scott D Solomon, Natalie Staplin, Muthiah Vaduganathan, Christoph Wanner, David Collins Wheeler, Faiez Zannad, Yujie Zhao, Hiddo J Lambers Heerspink, Marc S Sabatine, Stephen D Wiviott
Sodium-Glucose Cotransporter-2 Inhibitors and Major Adverse Cardiovascular Outcomes: A SMART-C Collaborative Meta-Analysis. Circulation 149 (23) (2024)
Milton Packer, John G F Cleland, Johann Bauersachs
Great Debate: SGLT2 inhibitors should be first-line treatment in heart failure with reduced ejection fraction. European heart journal 45 (25) (2024)
Milton Packer
Left Ventricular Ejection Fraction in Heart Failure: Crazy, Stupid Love-and Maybe, Redemption. Journal of the American Heart Association 13 (8) (2024)
Jawad Haider Butt, John Joseph Valentine McMurray, Brian Lee Claggett, Pardeep S Jhund, Brendon L Neuen, Finnian R Mc Causland, Akshay S Desai, Carolyn Su Ping Lam, Bertram Pitt, Marc A Pfeffer, Milton Packer, Iris Beldhuis, Carolyn S P Lam, Faiez Zannad, Hiddo J Lambers Heerspink, Scott D Solomon, Muthiah Vaduganathan
Therapeutic Effects of Heart Failure Medical Therapies on Standardized Kidney Outcomes: Comprehensive Individual Participant-Level Analysis of 6 Randomized Clinical Trials. Circulation (2024)
Milton Packer, Stefan D Anker, Javed Butler, John G F Cleland, Paul R Kalra, Robert J Mentz, Piotr Ponikowski, Khawaja M Talha
Redefining Iron Deficiency in Patients With Chronic Heart Failure. Circulation (2024)
Milton Packer, Stefan D Anker, Javed Butler, John G F Cleland, Paul R Kalra, Robert J Mentz, Piotr Ponikowski, Khawaja M Talha
Redefining Iron Deficiency in Patients With Chronic Heart Failure. Circulation (2024)
Milton Packer, John G F Cleland, Johann Bauersachs
Great Debate: SGLT2 inhibitors should be first-line treatment in heart failure with reduced ejection fraction. European heart journal (2024)
Milton Packer, Stefan D Anker, Javed Butler, John G F Cleland, Paul R Kalra, Robert J Mentz, Piotr Ponikowski
Identification of three mechanistic pathways for iron-deficient heart failure. European heart journal 45 (26) (2024)
Natasha L Patel-Murray, Luqing Zhang, Brian Lee Claggett, Dongchu Xu, Pablo Serrano-Fernandez, Margaret L Healey, Simon Wandel, Chien-Wei Chen, Jaison Jacob, Huilei Xu, Gordon M Turner, William Chutkow, Denise P Yates, Christopher J O'Donnell, Margaret F Prescott, Martin P Lefkowitz, Claudio R Gimpelewicz, Michael T Beste, Faye Zhao, Liangke Gou, Akshay S Desai, Pardeep S Jhund, Milton Packer, Marc A Pfeffer, Margaret M Redfield, Jean-Lucien Rouleau, Faiez Zannad, Michael R Zile, John Joseph Valentine McMurray, Michael M Mendelson, Scott D Solomon, Jonathan W Cunningham
Aptamer Proteomics for Biomarker Discovery in Heart Failure With Preserved Ejection Fraction: The PARAGON-HF Proteomic Substudy. Journal of the American Heart Association (2024)
Milton Packer
Left Ventricular Ejection Fraction in Heart Failure: Crazy, Stupid Love-and Maybe, Redemption. Journal of the American Heart Association 13 (8) (2024)
Milton Packer
Left Ventricular Ejection Fraction in Heart Failure: Crazy, Stupid Love-and Maybe, Redemption. Journal of the American Heart Association 13 (8) (2024)
Siddharth M Patel, Yu Mi Kang, KyungAh Im, Brendon L Neuen, Stefan D Anker, Deepak L Bhatt, Javed Butler, David Z I Cherney, Brian Lee Claggett, Robert A Fletcher, William G Herrington, Catherine M Viscoli, Meg J Jardine, Kenneth W Mahaffey, Darren K McGuire, John Joseph Valentine McMurray, Bruce C Neal, Milton Packer, Vlado Perkovic, Scott D Solomon, Natalie Staplin, Muthiah Vaduganathan, Christoph Wanner, David Collins Wheeler, Faiez Zannad, Yujie Zhao, Hiddo J Lambers Heerspink, Marc S Sabatine, Stephen D Wiviott
Sodium-Glucose Cotransporter-2 Inhibitors and Major Adverse Cardiovascular Outcomes: A SMART-C Collaborative Meta-Analysis. Circulation 149 (23) (2024)
Siddharth M Patel, Yu Mi Kang, KyungAh Im, Brendon L Neuen, Stefan D Anker, Deepak L Bhatt, Javed Butler, David Z I Cherney, Brian Lee Claggett, Robert A Fletcher, William G Herrington, Catherine M Viscoli, Meg J Jardine, Kenneth W Mahaffey, Darren K McGuire, John Joseph Valentine McMurray, Bruce C Neal, Milton Packer, Vlado Perkovic, Scott D Solomon, Natalie Staplin, Muthiah Vaduganathan, Christoph Wanner, David Collins Wheeler, Faiez Zannad, Yujie Zhao, Hiddo J Lambers Heerspink, Marc S Sabatine, Stephen D Wiviott
Sodium Glucose Co-transporter 2 Inhibitors and Major Adverse Cardiovascular Outcomes: A SMART-C Collaborative Meta-Analysis. Circulation (2024)
Milton Packer
Left Ventricular Ejection Fraction in Heart Failure: Crazy, Stupid Love-and Maybe, Redemption. Journal of the American Heart Association (2024)
Siddharth M Patel, Yu Mi Kang, KyungAh Im, Brendon L Neuen, Stefan D Anker, Deepak L Bhatt, Javed Butler, David Z I Cherney, Brian Lee Claggett, Robert A Fletcher, William G Herrington, Catherine M Viscoli, Meg J Jardine, Kenneth W Mahaffey, Darren K McGuire, John Joseph Valentine McMurray, Bruce C Neal, Milton Packer, Vlado Perkovic, Scott D Solomon, Natalie Staplin, Muthiah Vaduganathan, Christoph Wanner, David Collins Wheeler, Faiez Zannad, Yujie Zhao, Hiddo J Lambers Heerspink, Marc S Sabatine, Stephen D Wiviott
Sodium-Glucose Cotransporter-2 Inhibitors and Major Adverse Cardiovascular Outcomes: A SMART-C Collaborative Meta-Analysis. Circulation 149 (23) (2024)
Natasha L Patel-Murray, Luqing Zhang, Brian Lee Claggett, Dongchu Xu, Pablo Serrano-Fernandez, Margaret L Healey, Simon Wandel, Chien-Wei Chen, Jaison Jacob, Huilei Xu, Gordon M Turner, William Chutkow, Denise P Yates, Christopher J O'Donnell, Margaret F Prescott, Martin P Lefkowitz, Claudio R Gimpelewicz, Michael T Beste, Faye Zhao, Liangke Gou, Akshay S Desai, Pardeep S Jhund, Milton Packer, Marc A Pfeffer, Margaret M Redfield, Jean-Lucien Rouleau, Faiez Zannad, Michael R Zile, John Joseph Valentine McMurray, Michael M Mendelson, Scott D Solomon, Jonathan W Cunningham
Aptamer Proteomics for Biomarker Discovery in Heart Failure With Preserved Ejection Fraction: The PARAGON-HF Proteomic Substudy. Journal of the American Heart Association 13 (13) (2024)
Milton Packer, Stefan D Anker, Javed Butler, John G F Cleland, Paul R Kalra, Robert J Mentz, Piotr Ponikowski
Identification of three mechanistic pathways for iron-deficient heart failure. European heart journal (2024)
Milton Packer
Mechanisms of enhanced renal and hepatic erythropoietin synthesis by sodium-glucose cotransporter 2 inhibitors. European heart journal (2023)
Mingming Yang, Toru Kondo, Jawad Haider Butt, William T Abraham, Inder S Anand, Akshay S Desai, Lars Køber, Milton Packer, Marc A Pfeffer, Jean L Rouleau, Marc S Sabatine, Scott D Solomon, Karl Swedberg, Michael R Zile, Pardeep S Jhund, John Joseph Valentine McMurray
Stroke in patients with heart failure and reduced or preserved ejection fraction. European heart journal (2023)
Milton Packer, Christopher S Wilcox, Jeffrey M Testani
Critical Analysis of the Effects of SGLT2 Inhibitors on Renal Tubular Sodium, Water and Chloride Homeostasis and Their Role in Influencing Heart Failure Outcomes. Circulation 148 (4) (2023)
Paolo Tolomeo, Jawad H Butt, Toru Kondo, Gianluca Calogero Campo, Akshay S Desai, Pardeep S Jhund, Lars Valeur Køber, Martin P Lefkowitz, Jean L Rouleau, Scott D Solomon, Karl Swedberg, Muthiah Vaduganathan, Michael R Zile, Milton Packer, John Joseph Valentine McMurray
Importance of cystatin C in estimating glomerular filtration rate: the PARADIGM-HF trial. European heart journal (2023)
Milton Packer
Mechanisms of enhanced renal and hepatic erythropoietin synthesis by sodium-glucose cotransporter 2 inhibitors. European heart journal (2023)
Milton Packer
SGLT2 inhibitors: role in protective reprogramming of cardiac nutrient transport and metabolism. Nature reviews. Cardiology (2023)
Milton Packer
SGLT2 inhibitors: role in protective reprogramming of cardiac nutrient transport and metabolism. Nature reviews. Cardiology (2023)
Milton Packer, Javed Butler, Cordula Zeller, Stuart J Pocock, Martina Brueckmann, Joao Pedro Ferreira, Gerasimos S Filippatos, Muhammad Shariq Usman, Faiez Zannad, Stefan D Anker
Blinded Withdrawal of Long-Term Randomized Treatment With Empagliflozin or Placebo in Patients With Heart Failure. Circulation (2023)
Subodh Verma, Nitish K Dhingra, Marc P Bonaca, Javed Butler, Stefan D Anker, Joao Pedro Ferreira, Gerasimos S Filippatos, James L Januzzi, Carolyn Su Ping Lam, Naveed Sattar, Tomoko Iwata, Matias Nordaby, Martina Brueckmann, Stuart J Pocock, Milton Packer, null null
Presence of Peripheral Artery Disease Is Associated With Increased Risk of Heart Failure Events: Insights From EMPEROR-Pooled. Arteriosclerosis, thrombosis, and vascular biology (2023)
Toru Kondo, Pooja Dewan, Inder S Anand, Akshay S Desai, Milton Packer, Michael R Zile, Marc A Pfeffer, Scott D Solomon, William T Abraham, Sanjiv J Shah, Carolyn Su Ping Lam, Pardeep S Jhund, John Joseph Valentine McMurray
Clinical Characteristics and Outcomes in Patients With Heart Failure: Are There Thresholds and Inflection Points in Left Ventricular Ejection Fraction and Thresholds Justifying a Clinical Classification? Circulation (2023)
Toru Kondo, Karola S Jering, Pardeep S Jhund, Inder S Anand, Akshay S Desai, Carolyn Su Ping Lam, Aldo Pietro Maggioni, Felipe A Martinez, Milton Packer, Mark Colquhoun Petrie, Marc A Pfeffer, Margaret M Redfield, Jean L Rouleau, Dirk J van Veldhuisen, Faiez Zannad, Michael R Zile, Scott D Solomon, John Joseph Valentine McMurray
Predicting Stroke in Heart Failure and Preserved Ejection Fraction Without Atrial Fibrillation. Circulation. Heart failure (2023)
Jawad H Butt, Mark Colquhoun Petrie, Pardeep S Jhund, Naveed Sattar, Akshay S Desai, Lars Køber, Jean L Rouleau, Karl Swedberg, Michael R Zile, Scott D Solomon, Milton Packer, John Joseph Valentine McMurray
Anthropometric measures and adverse outcomes in heart failure with reduced ejection fraction: revisiting the obesity paradox. European heart journal (2023)
James P Curtain, Carly Adamson, Toru Kondo, Jawad Haider Butt, Akshay S Desai, Faiez Zannad, Jean L Rouleau, Luis E Rohde, Lars Kober, Inder S Anand, Dirk J van Veldhuisen, Michael R Zile, Martin P Lefkowitz, Scott D Solomon, Milton Packer, Mark Colquhoun Petrie, Pardeep S Jhund, John Joseph Valentine McMurray
Investigator-reported ventricular arrhythmias and mortality in heart failure with mildly reduced or preserved ejection fraction. European heart journal 44 (8) (2023)
Joao Pedro Ferreira, Abhinav Sharma, Javed Butler, Milton Packer, Faiez Zannad, Francisco Vasques-Nóvoa, Adelino Leite-Moreira, João Sérgio Neves
Glucagon-like peptide-1 receptor agonists across the spectrum of heart failure. The Journal of clinical endocrinology and metabolism (2023)
James P Curtain, Carly Adamson, Toru Kondo, Jawad Butt, Akshay S Desai, Faiez Zannad, Jean L Rouleau, Luis E Rohde, Lars Kober, Inder S Anand, Dirk J van Veldhuisen, Michael R Zile, Martin P Lefkowitz, Scott D Solomon, Milton Packer, Mark Colquhoun Petrie, Pardeep S Jhund, John Joseph Valentine McMurray
Investigator-reported ventricular arrhythmias and mortality in heart failure with mildly reduced or preserved ejection fraction. European heart journal (2023)
Jawad H Butt, Wasyla Ibrahim, Pooja Dewan, Akshay S Desai, Lars Valeur Køber, Margaret F Prescott, Martin P Lefkowitz, Jean L Rouleau, Scott D Solomon, Michael R Zile, Milton Packer, Pardeep S Jhund, John Joseph Valentine McMurray
Urinary cGMP (Cyclic Guanosine Monophosphate)/BNP (B-Type Natriuretic Peptide) Ratio, Sacubitril/Valsartan, and Outcomes in Heart Failure With Reduced Ejection Fraction: An Analysis of the PARADIGM-HF Trial. Circulation. Heart failure 16 (3) (2023)
Joao Pedro Ferreira, Francisca A Saraiva, Abhinav Sharma, Francisco Vasques-Nóvoa, António Angélico-Gonçalves, Ana Rita Leite, Marta Borges-Canha, Davide Carvalho, Milton Packer, Faiez Zannad, Adelino Leite-Moreira, João Sérgio Neves
Glucagon-like peptide 1 receptor agonists in patients with type 2 diabetes with and without chronic heart failure: a meta-analysis of randomized placebo-controlled outcome trials. Diabetes, obesity & metabolism (2023)
Milton Packer
Mechanisms of enhanced renal and hepatic erythropoietin synthesis by sodium-glucose cotransporter 2 inhibitors. European heart journal (2023)
Milton Packer
Fetal Reprogramming of Nutrient Surplus Signaling, O-GlcNAcylation, and the Evolution of Chronic Kidney Disease. Journal of the American Society of Nephrology : JASN (2023)
Milton Packer, Tariq Jamal Siddiqi, Javed Butler
Drugs that slow the progression of diabetic kidney disease: are renoprotective effects attenuated in heart failure? European heart journal (2023)
Milton Packer
Alleviation of Anemia by SGLT2 Inhibitors in Patients with CKD: Mechanisms and Results of Long-Term Placebo-Controlled Trials. Clinical journal of the American Society of Nephrology : CJASN (2023)
James P Curtain, Carly Adamson, Toru Kondo, Jawad Butt, Akshay S Desai, Faiez Zannad, Jean L Rouleau, Luis E Rohde, Lars Kober, Inder S Anand, Dirk J van Veldhuisen, Michael R Zile, Martin P Lefkowitz, Scott D Solomon, Milton Packer, Mark Colquhoun Petrie, Pardeep S Jhund, John Joseph Valentine McMurray
Investigator-reported ventricular arrhythmias and mortality in heart failure with mildly reduced or preserved ejection fraction. European heart journal (2023)
Jawad H Butt, Wasyla Ibrahim, Pooja Dewan, Akshay S Desai, Lars Valeur Køber, Margaret F Prescott, Martin P Lefkowitz, Jean L Rouleau, Scott D Solomon, Michael R Zile, Milton Packer, Pardeep S Jhund, John Joseph Valentine McMurray
Urinary cGMP (Cyclic Guanosine Monophosphate)/BNP (B-Type Natriuretic Peptide) Ratio, Sacubitril/Valsartan, and Outcomes in Heart Failure With Reduced Ejection Fraction: An Analysis of the PARADIGM-HF Trial. Circulation. Heart failure 16 (3) (2023)
Joao Pedro Ferreira, Francisca A Saraiva, Abhinav Sharma, Francisco Vasques-Nóvoa, António Angélico-Gonçalves, Ana Rita Leite, Marta Borges-Canha, Davide Carvalho, Milton Packer, Faiez Zannad, Adelino Leite-Moreira, João Sérgio Neves
Glucagon-like peptide 1 receptor agonists in patients with type 2 diabetes with and without chronic heart failure: A meta-analysis of randomized placebo-controlled outcome trials. Diabetes, obesity & metabolism (2023)
James P Curtain, Carly Adamson, Toru Kondo, Jawad Butt, Akshay S Desai, Faiez Zannad, Jean L Rouleau, Luis E Rohde, Lars Kober, Inder S Anand, Dirk J van Veldhuisen, Michael R Zile, Martin P Lefkowitz, Scott D Solomon, Milton Packer, Mark Colquhoun Petrie, Pardeep S Jhund, John Joseph Valentine McMurray
Investigator-reported ventricular arrhythmias and mortality in heart failure with mildly reduced or preserved ejection fraction. European heart journal (2023)
James P Curtain, Carly Adamson, Toru Kondo, Jawad Haider Butt, Akshay S Desai, Faiez Zannad, Jean L Rouleau, Luis E Rohde, Lars Kober, Inder S Anand, Dirk J van Veldhuisen, Michael R Zile, Martin P Lefkowitz, Scott D Solomon, Milton Packer, Mark Colquhoun Petrie, Pardeep S Jhund, John Joseph Valentine McMurray
Investigator-reported ventricular arrhythmias and mortality in heart failure with mildly reduced or preserved ejection fraction. European heart journal 44 (8) (2023)
Milton Packer
Potassium binders for patients with heart failure? The real enlightenment of the DIAMOND trial. European heart journal 43 (41) (2022)
Michael Böhm, Stefan D Anker, Felix Mahfoud, Lucas Lauder, Gerasimos S Filippatos, Joao Pedro Ferreira, Stuart J Pocock, Martina Brueckmann, Ilias Saloustros, Elke Schüler, Christoph Wanner, Faiez Zannad, Milton Packer, Javed Butler
Empagliflozin, irrespective of blood pressure, improves outcomes in heart failure with preserved ejection fraction: the EMPEROR-Preserved trial. European heart journal (2022)
Muhammad Shahzeb Khan, Javed Butler, Stefan D Anker, Gerasimos S Filippatos, Joao Pedro Ferreira, Stuart J Pocock, James L Januzzi, Iliana L Piña, Michael Böhm, Piotr Ponikowski, Subodh Verma, Martina Brueckmann, Ola Vedin, Cordula Zeller, Faiez Zannad, Milton Packer
Impact of Empagliflozin in Heart Failure With Reduced Ejection Fraction in Patients With Ischemic Versus Nonischemic Cause. Journal of the American Heart Association 12 (1) (2022)
Muhammad Shahzeb Khan, Javed Butler, Stefan D Anker, Gerasimos S Filippatos, Joao Pedro Ferreira, Stuart J Pocock, James L Januzzi, Iliana L Piña, Michael Böhm, Piotr Ponikowski, Subodh Verma, Martina Brueckmann, Ola Vedin, Cordula Zeller, Faiez Zannad, Milton Packer
Impact of Empagliflozin in Heart Failure With Reduced Ejection Fraction in Patients With Ischemic Versus Nonischemic Cause. Journal of the American Heart Association 12 (1) (2022)
Muhammad Shahzeb Khan, George L Bakris, Milton Packer, Izza Shahid, Stefan D Anker, Gregory Y H Lip, Christoph Wanner, Matthew R Weir, Faiez Zannad, Javed Butler
Kidney function assessment and endpoint ascertainment in clinical trials. European heart journal 43 (14) (2022)
João Sérgio Neves, Francisco Vasques-Nóvoa, Marta Borges-Canha, Ana Rita Leite, Abhinav Sharma, Davide Carvalho, Milton Packer, Faiez Zannad, Adelino Leite-Moreira, Joao Pedro Ferreira
Risk of adverse events with liraglutide in heart failure with reduced ejection fraction: A post hoc analysis of the FIGHT trial. Diabetes, obesity & metabolism (2022)
Muhammad Shahzeb Khan, Javed Butler, Stefan D Anker, Gerasimos S Filippatos, Joao Pedro Ferreira, Stuart J Pocock, James L Januzzi, Iliana L Piña, Michael Böhm, Piotr Ponikowski, Subodh Verma, Martina Brueckmann, Ola Vedin, Cordula Zeller, Faiez Zannad, Milton Packer
Impact of Empagliflozin in Heart Failure With Reduced Ejection Fraction in Patients With Ischemic Versus Nonischemic Cause. Journal of the American Heart Association 12 (1) (2022)
Muhammad Shahzeb Khan, Javed Butler, Stefan D Anker, Gerasimos S Filippatos, Joao Pedro Ferreira, Stuart J Pocock, James L Januzzi, Iliana L Piña, Michael Böhm, Piotr Ponikowski, Subodh Verma, Martina Brueckmann, Ola Vedin, Cordula Zeller, Faiez Zannad, Milton Packer
Impact of Empagliflozin in Heart Failure With Reduced Ejection Fraction in Patients With Ischemic Versus Nonischemic Cause. Journal of the American Heart Association 12 (1) (2022)
Milton Packer
Critical Reanalysis of the Mechanisms Underlying the Cardiorenal Benefits of SGLT2 Inhibitors and Reaffirmation of the Nutrient Deprivation Signaling/Autophagy Hypothesis. Circulation 146 (18) (2022)
Li Shen, Pardeep Singh Jhund, Kieran Francis Docherty, Muthiah Vaduganathan, Mark Colquhoun Petrie, Akshay Suvas Desai, Lars Køber, Morten Schou, Milton Packer, Scott David Solomon, Xingwei Zhang, John Joseph Valentine McMurray
Accelerated and personalized therapy for heart failure with reduced ejection fraction. European heart journal 43 (27) (2022)
Subodh Verma, Nitish K Dhingra, Javed Butler, Stefan D Anker, Joao Pedro Ferreira, Gerasimos S Filippatos, James L Januzzi, Carolyn Su Ping Lam, Naveed Sattar, Egon Pfarr, Matias Nordaby, Martina Brueckmann, Stuart J Pocock, Faiez Zannad, Milton Packer
Empagliflozin in Black Versus White Patients with Heart Failure: Analysis of EMPEROR-Pooled. Circulation (2022)
Muhammad Shahzeb Khan, Javed Butler, Stefan D Anker, Gerasimos S Filippatos, Joao Pedro Ferreira, Stuart J Pocock, James L Januzzi, Iliana L Piña, Michael Böhm, Piotr Ponikowski, Subodh Verma, Martina Brueckmann, Ola Vedin, Cordula Zeller, Faiez Zannad, Milton Packer
Impact of Empagliflozin in Heart Failure With Reduced Ejection Fraction in Patients With Ischemic Versus Nonischemic Cause. Journal of the American Heart Association (2022)
Wolfram Döhner, Stefan D Anker, Javed Butler, Faiez Zannad, Gerasimos Filippatos, João Pedro Ferreira, Afshin Salsali, Carolyn Kaempfer, Martina Brueckmann, Stuart J Pocock, James L Januzzi, Milton Packer
Uric acid and sodium-glucose cotransporter-2 inhibition with empagliflozin in heart failure with reduced ejection fraction: the EMPEROR-reduced trial. European heart journal 43 (36) (2022)
Luqing Zhang, Jonathan W Cunningham, Brian Lee Claggett, Jaison Jacob, Michael M Mendelson, Pablo Serrano-Fernandez, Sergio Kaiser, Denise P Yates, Margaret L Healey, Chien-Wei Chen, Gordon M Turner, Natasha L Patel-Murray, Faye Zhao, Michael T Beste, Jason M Laramie, William T Abraham, Pardeep S Jhund, Lars Valeur Køber, Milton Packer, Jean Rouleau, Michael R Zile, Margaret F Prescott, Martin Lefkowitz, John Joseph Valentine McMurray, Scott D Solomon, William Chutkow
Aptamer Proteomics for Biomarker Discovery in Heart Failure With Reduced Ejection Fraction. Circulation 146 (18) (2022)
Toru Kondo, Azmil H Abdul-Rahim, Atefeh Talebi, William T Abraham, Akshay S Desai, Kenneth Dickstein, Silvio E Inzucchi, Lars Køber, Mikhail N Kosiborod, Felipe A Martinez, Milton Packer, Mark Petrie, Piotr Ponikowski, Jean L Rouleau, Marc S Sabatine, Karl Swedberg, Michael R Zile, Scott D Solomon, Pardeep S Jhund, John Joseph Valentine McMurray
Predicting stroke in heart failure and reduced ejection fraction without atrial fibrillation. European heart journal 43 (42) (2022)
Milton Packer
Six lessons learned from the use of SGLT2 inhibitors in patients with heart failure. Nature reviews. Cardiology 19 (8) (2022)
Milton Packer
Alleviation of functional iron deficiency by SGLT2 inhibition in patients with type 2 diabetes. Diabetes, obesity & metabolism (2022)
Muhammad Shahzeb Khan, Javed Butler, Stefan D Anker, Gerasimos S Filippatos, Joao Pedro Ferreira, Stuart J Pocock, James L Januzzi, Iliana L Piña, Michael Böhm, Piotr Ponikowski, Subodh Verma, Martina Brueckmann, Ola Vedin, Cordula Zeller, Faiez Zannad, Milton Packer
Impact of Empagliflozin in Heart Failure With Reduced Ejection Fraction in Patients With Ischemic Versus Nonischemic Cause. Journal of the American Heart Association 12 (1) (2022)
Milton Packer
Alleviation of Functional Iron Deficiency by SGLT2 Inhibition in Patients With Type 2 Diabetes. Diabetes, obesity & metabolism (2022)
Javed Butler, Gerasimos S Filippatos, Tariq Jamal Siddiqi, Joao Pedro Ferreira, Martina Brueckmann, Edimar Alcides Bocchi, Michael Böhm, Vijay K Chopra, Nadia Giannetti, Tomoko Iwata, James L Januzzi, Sanjay Kaul, Iliana L Piña, Piotr Ponikowski, Ursula Rauch, Sanjiv J Shah, Michele Senni, Mikhail Sumin, Subodh Verma, Jian Zhang, Stuart J Pocock, Faiez Zannad, Milton Packer, Stefan D Anker
Effects of Empagliflozin in Women and Men With Heart Failure and Preserved Ejection Fraction. Circulation 146 (14) (2022)
Faiez Zannad, João Pedro Ferreira, Javed Butler, Gerasimos Filippatos, James L Januzzi, Mikhail Sumin, Matthias Zwick, Maral Saadati, Stuart J Pocock, Naveed Sattar, Stefan D Anker, Milton Packer
Effect of Empagliflozin on Circulating Proteomics in Heart Failure: Mechanistic Insights from the EMPEROR Program. European heart journal (2022)
Joao Pedro Ferreira, Faiez Zannad, Javed Butler, Gerasimos Filipattos, Ivana Ritter, Elke Schüler, Bettina J Kraus, Stuart J Pocock, Stefan D Anker, Milton Packer
Empagliflozin and serum potassium in heart failure: an analysis from EMPEROR-Pooled. European heart journal 43 (31) (2022)
Gerasimos S Filippatos, Javed Butler, Dimitrios Farmakis, Faiez Zannad, Anne Pernille Ofstad, Joao Pedro Ferreira, Jennifer B Green, Julio Rosenstock, Sven Schnaidt, Martina Brueckmann, Stuart J Pocock, Milton Packer, Stefan D Anker, null null
Empagliflozin for Heart Failure With Preserved Left Ventricular Ejection Fraction With and Without Diabetes. Circulation 146 (9) (2022)
Muhammad Shahzeb Khan, Javed Butler, Stefan D Anker, Gerasimos S Filippatos, Joao Pedro Ferreira, Stuart J Pocock, James L Januzzi, Iliana L Piña, Michael Böhm, Piotr Ponikowski, Subodh Verma, Martina Brueckmann, Ola Vedin, Cordula Zeller, Faiez Zannad, Milton Packer
Impact of Empagliflozin in Heart Failure With Reduced Ejection Fraction in Patients With Ischemic Versus Nonischemic Cause. Journal of the American Heart Association 12 (1) (2022)
Stefan D Anker, Javed Butler, Gerasimos Filippatos, João P Ferreira, Edimar Bocchi, Michael Böhm, Hans-Peter Brunner-La Rocca, Dong-Ju Choi, Vijay Chopra, Eduardo Chuquiure-Valenzuela, Nadia Giannetti, Juan Esteban Gomez-Mesa, Stefan Janssens, James L Januzzi, Jose R Gonzalez-Juanatey, Bela Merkely, Stephen J Nicholls, Sergio V Perrone, Ileana L Piña, Piotr Ponikowski, Michele Senni, David Sim, Jindrich Spinar, Iain Squire, Stefano Taddei, Hiroyuki Tsutsui, Subodh Verma, Dragos Vinereanu, Jian Zhang, Peter Carson, Carolyn Su Ping Lam, Nikolaus Marx, Cordula Zeller, Naveed Sattar, Waheed Jamal, Sven Schnaidt, Janet M Schnee, Martina Brueckmann, Stuart J Pocock, Faiez Zannad, Milton Packer, null null
Empagliflozin in Heart Failure with a Preserved Ejection Fraction. The New England journal of medicine 385 (16) (2021)
Milton Packer, Javed Butler, Faiez Zannad, Gerasimos Filippatos, Joao Pedro Ferreira, Stuart J Pocock, Peter Carson, Inder Anand, Wolfram Doehner, Markus Haass, Michel Komajda, Alan Miller, Steen Pehrson, John R Teerlink, Sven Schnaidt, Cordula Zeller, Janet M Schnee, Stefan D Anker
Effect of Empagliflozin on Worsening Heart Failure Events in Patients With Heart Failure and Preserved Ejection Fraction: EMPEROR-Preserved Trial. Circulation 144 (16) (2021)
Milton Packer, Faiez Zannad, Stefan D Anker
Heart Failure and a Preserved Ejection Fraction: A Side-by-Side Examination of the PARAGON-HF and EMPEROR-Preserved Trials. Circulation 144 (15) (2021)
Milton Packer, Javed Butler, Faiez Zannad, Stuart J Pocock, Gerasimos Filippatos, João P Ferreira, Martina Brueckmann, Waheed Jamal, Cordula Zeller, Christoph Wanner, Stefan D Anker, null null
Empagliflozin and Major Renal Outcomes in Heart Failure. The New England journal of medicine 385 (16) (2021)
Javed Butler, Gerasimos S Filippatos, Tariq Jamal Siddiqi, Martina Brueckmann, Michael Böhm, Vijay K Chopra, Joao Pedro Ferreira, James L Januzzi, Sanjay Kaul, Iliana L Piña, Piotr Ponikowski, Sanjiv J Shah, Michele Senni, Ola Vedin, Subodh Verma, Barbara Peil, Stuart J Pocock, Faiez Zannad, Milton Packer, Stefan D Anker
Empagliflozin, Health Status, and Quality of Life in Patients with Heart Failure and Preserved Ejection Fraction: The EMPEROR-Preserved Trial. Circulation (2021)
Milton Packer
What causes exertional dyspnoea in patients with atrial fibrillation? Implications for catheter ablation in patients with heart failure. European journal of heart failure 23 (5) (2021)
Milton Packer
Interplay of adenosine monophosphate-activated protein kinase/sirtuin-1 activation and sodium influx inhibition mediates the renal benefits of sodium-glucose co-transporter-2 inhibitors in type 2 diabetes: A novel conceptual framework. Diabetes, obesity & metabolism 22 (5) (2020)
Milton Packer, Stefan D Anker, Javed Butler, Gerasimos Filippatos, Stuart J Pocock, Peter Carson, James Januzzi, Subodh Verma, Hiroyuki Tsutsui, Martina Brueckmann, Waheed Jamal, Karen Kimura, Janet Schnee, Cordula Zeller, Daniel Cotton, Edimar Bocchi, Michael Böhm, Dong-Ju Choi, Vijay Chopra, Eduardo Chuquiure, Nadia Giannetti, Stefan Janssens, Jian Zhang, Jose R Gonzalez Juanatey, Sanjay Kaul, Hans-Peter Brunner-La Rocca, Bela Merkely, Stephen J Nicholls, Sergio Perrone, Ileana Pina, Piotr Ponikowski, Naveed Sattar, Michele Senni, Marie-France Seronde, Jindrich Spinar, Iain Squire, Stefano Taddei, Christoph Wanner, Faiez Zannad, null null
Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure. The New England journal of medicine 383 (15) (2020)
Milton Packer
Role of Impaired Nutrient and Oxygen Deprivation Signaling and Deficient Autophagic Flux in Diabetic CKD Development: Implications for Understanding the Effects of Sodium-Glucose Cotransporter 2-Inhibitors. Journal of the American Society of Nephrology : JASN 31 (5) (2020)
Milton Packer
SGLT2 Inhibitors Produce Cardiorenal Benefits by Promoting Adaptive Cellular Reprogramming to Induce a State of Fasting Mimicry: A Paradigm Shift in Understanding Their Mechanism of Action. Diabetes care 43 (3) (2020)
Milton Packer
Autophagy-dependent and -independent modulation of oxidative and organellar stress in the diabetic heart by glucose-lowering drugs. Cardiovascular diabetology 19 (1) (2020)
Milton Packer
Heightened risk of intensive rate control in patients with atrial fibrillation who are obese or have type 2 diabetes: A critical review and re-evaluation. Journal of cardiovascular electrophysiology 30 (12) (2019)
Milton Packer
Critical role of the epicardium in mediating cardiac inflammation and fibrosis in patients with type 2 diabetes. Diabetes, obesity & metabolism 21 (8) (2019)
Milton Packer
Disease-treatment interactions in the management of patients with obesity and diabetes who have atrial fibrillation: the potential mediating influence of epicardial adipose tissue. Cardiovascular diabetology 18 (1) (2019)
Milton Packer
Role of the sodium-hydrogen exchanger in mediating the renal effects of drugs commonly used in the treatment of type 2 diabetes. Diabetes, obesity & metabolism 20 (4) (2018)
Milton Packer
Have we really demonstrated the cardiovascular safety of anti-hyperglycaemic drugs? Rethinking the concepts of macrovascular and microvascular disease in type 2 diabetes. Diabetes, obesity & metabolism 20 (5) (2018)
Milton Packer
Higher mortality rate in patients with heart failure who are taking commonly prescribed antidiabetic medications and achieve recommended levels of glycaemic control. Diabetes, obesity & metabolism 20 (7) (2018)
Milton Packer
Do sodium-glucose co-transporter-2 inhibitors prevent heart failure with a preserved ejection fraction by counterbalancing the effects of leptin? A novel hypothesis. Diabetes, obesity & metabolism 20 (6) (2018)

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Milton Packer (M Packer)