Predicting stroke in heart failure and reduced ejection fraction without atrial fibrillation.
Toru KondoAzmil H Abdul-RahimAtefeh TalebiWilliam T AbrahamAkshay S DesaiKenneth DicksteinSilvio E InzucchiLars KøberMikhail N KosiborodFelipe A MartinezMilton PackerMark PetriePiotr PonikowskiJean L RouleauMarc S SabatineKarl SwedbergMichael R ZileScott D SolomonPardeep S JhundJohn Joseph Valentine McMurrayPublished in: European heart journal (2022)
It is possible to identify a subset of HFrEF patients without AF with a stroke-risk equivalent to that of patients with AF who are not anticoagulated. In these patients, the risk-to-benefit balance might justify the use of prophylactic anticoagulation, but this hypothesis needs to be tested prospectively.
Keyphrases
- atrial fibrillation
- heart failure
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- oral anticoagulants
- left atrial
- direct oral anticoagulants
- venous thromboembolism
- percutaneous coronary intervention
- patient reported outcomes
- acute coronary syndrome
- brain injury
- blood brain barrier