Noboru Mizushima (Noboru MIzushima)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 63

Top Venues

Autophagy

The Journal of cell biology

eLife

Nature communications

The University of Tokyo

Tokyo Medical and Dental Univeristy (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

The University of Tokyo

Japan

Professor

Education History

Tokyo Medical and Dental Univeristy

Japan

PHD

Publications

Saori Shinoda, Yuji Sakai, Takahide Matsui, Masaaki Uematsu, Ikuko Koyama-Honda, Jun-Ichi Sakamaki, Hayashi Yamamoto, Noboru Mizushima
Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation. eLife 12 (2024)
Tomoya Eguchi, Maria Sakurai, Yingxue Wang, Chieko Saito, Gen Yoshii, Thomas Wileman, Noboru Mizushima, Tomoki Kuwahara, Takeshi Iwatsubo
The V-ATPase-ATG16L1 axis recruits LRRK2 to facilitate the lysosomal stress response. The Journal of cell biology 223 (3) (2024)
Yuji Sakai, Satoru Takahashi, Ikuko Koyama-Honda, Chieko Saito, Noboru Mizushima
Experimental determination and mathematical modeling of standard shapes of forming autophagosomes. Nature communications 15 (1) (2024)
Saori Shinoda, Noboru Mizushima
Electrostatic maturation of the autophagosome. Autophagy (2024)
Yuji Sakai, Satoru Takahashi, Ikuko Koyama-Honda, Chieko Saito, Noboru Mizushima
Experimental determination and mathematical modeling of standard shapes of forming autophagosomes. Nature communications 15 (1) (2024)
Tomoya Eguchi, Maria Sakurai, Yingxue Wang, Chieko Saito, Gen Yoshii, Thomas Wileman, Noboru Mizushima, Tomoki Kuwahara, Takeshi Iwatsubo
The V-ATPase-ATG16L1 axis recruits LRRK2 to facilitate the lysosomal stress response. The Journal of cell biology 223 (3) (2024)
Tomoya Eguchi, Maria Sakurai, Yingxue Wang, Chieko Saito, Gen Yoshii, Thomas Wileman, Noboru Mizushima, Tomoki Kuwahara, Takeshi Iwatsubo
The V-ATPase-ATG16L1 axis recruits LRRK2 to facilitate the lysosomal stress response. The Journal of cell biology 223 (3) (2024)
Tomoya Eguchi, Maria Sakurai, Yingxue Wang, Chieko Saito, Gen Yoshii, Thomas Wileman, Noboru Mizushima, Tomoki Kuwahara, Takeshi Iwatsubo
The V-ATPase-ATG16L1 axis recruits LRRK2 to facilitate the lysosomal stress response. The Journal of cell biology 223 (3) (2024)
Yoshitaka Kurikawa, Ikuko Koyama-Honda, Norito Tamura, Seiichi Koike, Noboru Mizushima
Organelle landscape analysis using a multiparametric particle-based method. PLoS biology 22 (9) (2024)
Noboru Mizushima
Ubiquitin in autophagy and non-protein ubiquitination. Nature structural & molecular biology 31 (2) (2024)
Tomoya Eguchi, Maria Sakurai, Yingxue Wang, Chieko Saito, Gen Yoshii, Thomas Wileman, Noboru Mizushima, Tomoki Kuwahara, Takeshi Iwatsubo
The V-ATPase-ATG16L1 axis recruits LRRK2 to facilitate the lysosomal stress response. The Journal of cell biology 223 (3) (2024)
Saori Shinoda, Noboru Mizushima
Electrostatic maturation of the autophagosome. Autophagy (2024)
Noboru Mizushima
Ubiquitin in autophagy and non-protein ubiquitination. Nature structural & molecular biology 31 (2) (2024)
Saori Shinoda, Yuji Sakai, Takahide Matsui, Masaaki Uematsu, Ikuko Koyama-Honda, Jun-Ichi Sakamaki, Hayashi Yamamoto, Noboru Mizushima
Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation. eLife 12 (2024)
Yuji Sakai, Satoru Takahashi, Ikuko Koyama-Honda, Chieko Saito, Noboru Mizushima
Experimental determination and mathematical modeling of standard shapes of forming autophagosomes. Nature communications 15 (1) (2024)
Hayashi Yamamoto, Sidi Zhang, Noboru Mizushima
Autophagy genes in biology and disease. Nature reviews. Genetics (2023)
Hayashi Yamamoto, Sidi Zhang, Noboru Mizushima
Autophagy genes in biology and disease. Nature reviews. Genetics (2023)
Hayashi Yamamoto, Sidi Zhang, Noboru Mizushima
Autophagy genes in biology and disease. Nature reviews. Genetics (2023)
Taki Nishimura, Gianmarco Lazzeri, Noboru Mizushima, Roberto Covino, Sharon A Tooze
Unique amphipathic α helix drives membrane insertion and enzymatic activity of ATG3. Science advances 9 (25) (2023)
Nika Schuermans, Salima El Chehadeh, Dimitri Hemelsoet, Jérémie Gautheron, Marie-Christine Vantyghem, Sonia Nouioua, Meriem Tazir, Corinne Vigouroux, Martine Auclair, Elke Bogaert, Sara Dufour, Fumiya Okawa, Pascale Hilbert, Nike Van Doninck, Marie-Caroline Taquet, Toon Rosseel, Griet De Clercq, Elke Debackere, Carole Van Haverbeke, Ferroudja Ramdane Cherif, Jon Andoni Urtizberea, Jean-Baptiste Chanson, Benoit Funalot, François-Jérôme Authier, Sabine Kaya, Wim Terryn, Steven Callens, Bernard Depypere, Jo Van Dorpe, null null, Bruce Poppe, Francis Impens, Noboru Mizushima, Christel Depienne, Isabelle Jéru, Bart Dermaut
Loss of phospholipase PLAAT3 causes a mixed lipodystrophic and neurological syndrome due to impaired PPARγ signaling. Nature genetics (2023)
Hayashi Yamamoto, Sidi Zhang, Noboru Mizushima
Autophagy genes in biology and disease. Nature reviews. Genetics (2023)
Jun-Ichi Sakamaki, Noboru Mizushima
Conjugation of the ubiquitin family proteins to phospholipids. Autophagy (2022)
Willa Wen-You Yim, Hayashi Yamamoto, Noboru Mizushima
Annexins A1 and A2 are recruited to larger lysosomal injuries independently of ESCRTs to promote repair. FEBS letters 596 (8) (2022)
Sidi Zhang, Noboru Mizushima
The autophagy pathway beyond model organisms: an evolutionary perspective. Autophagy (2022)
Joost C M Holthuis, Helene Jahn, Anant K Menon, Noboru Mizushima
An alliance between lipid transfer proteins and scramblases for membrane expansion. Faculty reviews 11 (2022)
Halim Kusumaatmaja, Alexander I May, Mistianne Feeney, Joseph F McKenna, Noboru Mizushima, Lorenzo Frigerio, Roland L Knorr
Wetting of phase-separated droplets on plant vacuole membranes leads to a competition between tonoplast budding and nanotube formation. Proceedings of the National Academy of Sciences of the United States of America 118 (36) (2022)
Yutaro Hama, Hideaki Morishita, Noboru Mizushima
Regulation of ER-derived membrane dynamics by the DedA domain-containing proteins VMP1 and TMEM41B. EMBO reports 23 (2) (2022)
Jiawen Fu, Lin Zhao, Yu Pang, Heming Chen, Hayashi Yamamoto, Yuntong Chen, Zhaoran Li, Noboru Mizushima, Honglin Jia
Apicoplast biogenesis mediated by ATG8 requires the ATG12-ATG5-ATG16L and SNAP29 complexes in Toxoplasma gondii . Autophagy (2022)
Ikuko Koyama-Honda, Noboru Mizushima
Transient visit of STX17 (syntaxin 17) to autophagosomes. Autophagy 18 (6) (2022)
Willa Wen-You Yim, Hayashi Yamamoto, Noboru Mizushima
A pulse-chasable reporter processing assay for mammalian autophagic flux with HaloTag. eLife 11 (2022)
Sidi Zhang, Euki Yazaki, Hirokazu Sakamoto, Hayashi Yamamoto, Noboru Mizushima
Evolutionary diversification of the autophagy-related ubiquitin-like conjugation systems. Autophagy 18 (12) (2022)
Tomoko Ohshima, Hayashi Yamamoto, Yuriko Sakamaki, Chieko Saito, Noboru Mizushima
NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy. The Journal of cell biology 221 (10) (2022)
Haruka Chino, Akinori Yamasaki, Koji L Ode, Hiroki R Ueda, Nobuo N Noda, Noboru Mizushima
Phosphorylation by casein kinase 2 enhances the interaction between ER-phagy receptor TEX264 and ATG8 proteins. EMBO reports 23 (6) (2022)
Daniel J Klionsky, Giulia Petroni, Ravi K Amaravadi, Eric H Baehrecke, Andrea Balabio, Patricia Boya, José Manuel Bravo-San Pedro, Ken Cadwell, Francesco Cecconi, Augustine M K Choi, Mary E Choi, Charleen T Chu, Patrice Codogno, Maria Isabel Colombo, Ana Maria Cuervo, Vojo Deretic, Ivan Đikić, Zvulun Elazar, Eeva-Liisa Eskelinen, Gian Maria Fimia, David A Gewirtz, Douglas R Green, Malene Hansen, Marja Jäättelä, Terje Johansen, Gábor Juhász, Vassiliki Karantza, Claudine Kraft, Guido Kroemer, Nicholas T Ktistakis, Sharad Kumar, Carlos López-Otín, Kay F Macleod, Frank Madeo, Jennifer Martinez, Alicia Meléndez, Noboru Mizushima, Christian Münz, Josef M Penninger, Rushika M Perera, Mauro Piacentini, Fulvio M Reggiori, David C Rubinsztein, Kevin M Ryan, Junichi Sadoshima, Laura Santambrogio, Luca Scorrano, Hans-Uwe Simon, Anna Katharina Simon, Anne Simonsen, Alexandra Stolz, Nektarios Tavernarakis, Sharon A Tooze, Tamotsu Yoshimori, Junying Yuan, Zhenyu Yue, Qing Zhong, Lorenzo Galluzzi, Federico Pietrocola
Autophagy in major human diseases. The EMBO journal 40 (19) (2021)
Sidi Zhang, Yutaro Hama, Noboru Mizushima
The evolution of autophagy proteins - diversification in eukaryotes and potential ancestors in prokaryotes. Journal of cell science 134 (13) (2021)
Hideaki Morishita, Tomoya Eguchi, Noboru Mizushima
A new insight into the lens: cytosolic PLAAT phospholipases degrade organelles to make the lens transparent. Autophagy 17 (9) (2021)
Hideaki Morishita, Yuki Kanda, Noboru Mizushima
No air without autophagy: autophagy is important for lung and swim bladder inflation. Autophagy 17 (4) (2021)
Yutaro Hama, Sidi Zhang, Noboru Mizushima
ZZ domains keep cytosol to vacuole delivery whiZZing along. The EMBO journal 40 (15) (2021)
Hideaki Morishita, Tomoya Eguchi, Satoshi Tsukamoto, Yuriko Sakamaki, Satoru Takahashi, Chieko Saito, Ikuko Koyama-Honda, Noboru Mizushima
Organelle degradation in the lens by PLAAT phospholipases. Nature 592 (7855) (2021)
Yasuhiro Yamamoto, Haruka Chino, Satoshi Tsukamoto, Koji L Ode, Hiroki R Ueda, Noboru Mizushima
NEK9 regulates primary cilia formation by acting as a selective autophagy adaptor for MYH9/myosin IIA. Nature communications 12 (1) (2021)
Willa Wen-You Yim, Yoshitaka Kurikawa, Noboru Mizushima
An exploratory text analysis of the autophagy research field. Autophagy (2021)
Jaime Agudo-Canalejo, Sebastian Wolfgang Schultz, Haruka Chino, Simona M Migliano, Chieko Saito, Ikuko Koyama-Honda, Harald Alfred Stenmark, Andreas Brech, Alexander I May, Noboru Mizushima, Roland L Knorr
Wetting regulates autophagy of phase-separated compartments and the cytosol. Nature 591 (7848) (2021)
Sebastian W Schultz, Jaime Agudo-Canalejo, Haruka Chino, Simona M Migliano, Chieko Saito, Ikuko Koyama-Honda, Harald Stenmark, Andreas Brech, Noboru Mizushima, Roland L Knorr, Alexander I May
Should I bend or should I grow: the mechanisms of droplet-mediated autophagosome formation. Autophagy 17 (4) (2021)
Willa Wen-You Yim, Noboru Mizushima
Lysosome biology in autophagy. Cell discovery 6 (2020)
Noboru Mizushima, Beth Levine
Autophagy in Human Diseases. The New England journal of medicine 383 (16) (2020)
Shintaro Maeda, Hayashi Yamamoto, Lisa N Kinch, Christina M Garza, Satoru Takahashi, Chinatsu Otomo, Nick V Grishin, Stefano Forli, Noboru Mizushima, Takanori Otomo
Structure, lipid scrambling activity and role in autophagosome formation of ATG9A. Nature structural & molecular biology 27 (12) (2020)
Keigo Morita, Yutaro Hama, Noboru Mizushima
TMEM41B functions with VMP1 in autophagosome formation. Autophagy 15 (5) (2019)
Yu Pang, Hayashi Yamamoto, Hirokazu Sakamoto, Masahide Oku, Joe Kimanthi Mutungi, Mayurbhai Himatbhai Sahani, Yoshitaka Kurikawa, Kiyoshi Kita, Nobuo N Noda, Yasuyoshi Sakai, Honglin Jia, Noboru Mizushima
Evolution from covalent conjugation to non-covalent interaction in the ubiquitin-like ATG12 system. Nature structural & molecular biology 26 (4) (2019)
Shun-Saku Takahashi, Yu-Shin Sou, Tetsuya Saito, Akiko Kuma, Takayuki Yabe, Yuki Sugiura, Hyeon-Cheol Lee-Okada, Makoto Suematsu, Takehiko Yokomizo, Masato Koike, Shuji Terai, Noboru Mizushima, Satoshi Waguri, Masaaki Komatsu
Loss of autophagy impairs physiological steatosis by accumulation of NCoR1. Life science alliance 3 (1) (2019)
Tetsuya Saito, Akiko Kuma, Yuki Sugiura, Yoshinobu Ichimura, Miki Obata, Hiroshi Kitamura, Shujiro Okuda, Hyeon-Cheol Lee, Kazutaka Ikeda, Yumi Kanegae, Izumu Saito, Johan Auwerx, Hozumi Motohashi, Makoto Suematsu, Tomoyoshi Soga, Takehiko Yokomizo, Satoshi Waguri, Noboru Mizushima, Masaaki Komatsu
Autophagy regulates lipid metabolism through selective turnover of NCoR1. Nature communications 10 (1) (2019)
Noboru Mizushima
The ubiquitin E2 enzyme UBE2QL1 mediates lysophagy. EMBO reports 20 (10) (2019)
Hideaki Morishita, Yan G Zhao, Norito Tamura, Taki Nishimura, Yuki Kanda, Yuriko Sakamaki, Mitsuyo Okazaki, Dongfang Li, Noboru Mizushima
A critical role of VMP1 in lipoprotein secretion. eLife 8 (2019)
Vojo P Deretic, Eric R Prossnitz, Mark Burge, Matthew J Campen, Judy L Cannon, Ke Jian Liu, Larry A Sklar, Lee Allers, Sally Ann Garcia, Eric H Baehrecke, Christian Behrends, Francesco Cecconi, Patrice Codogno, Guang-Chao Chen, Zvulun Elazar, Eeva-Liisa Eskelinen, P Bernard Fourie, Devrim Gozuacik, Wanjin Hong, Gokhan Hotamisligi, Marja Jäättelä, Eun-Kyeong Jo, Terje Johansen, Gábor Juhász, Adi Kimchi, Nicholas Ktistakis, Guido Kroemer, Noboru Mizushima, Christian Münz, Fulvio Reggiori, David Rubinsztein, Kevin M Ryan, Kate Schroder, Anne Simonsen, Sharon A Tooze, Maria I Vaccaro, Tamotsu Yoshimori, Li Yu, Hong Zhang, Daniel J Klionsky
Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations. Autophagy 14 (6) (2019)
Takahide Matsui, Peidu Jiang, Saori Nakano, Yuriko Sakamaki, Hayashi Yamamoto, Noboru Mizushima
Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17. The Journal of cell biology 217 (8) (2018)
Noboru Mizushima
A brief history of autophagy from cell biology to physiology and disease. Nature cell biology 20 (5) (2018)
Keigo Morita, Yutaro Hama, Tamaki Izume, Norito Tamura, Toshihide Ueno, Yoshihiro Yamashita, Yuriko Sakamaki, Kaito Mimura, Hideaki Morishita, Wataru Shihoya, Osamu Nureki, Hiroyuki Mano, Noboru Mizushima
Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation. The Journal of cell biology 217 (11) (2018)
Noboru Mizushima, Takahide Matsui, Hayashi Yamamoto
YKT6 as a second SNARE protein of mammalian autophagosomes. Autophagy 15 (1) (2018)
Nora Wallot-Hieke, Neha Verma, David Schlütermann, Niklas Berleth, Jana Deitersen, Philip Böhler, Fabian Stuhldreier, Wenxian Wu, Sabine Seggewiß, Christoph Peter, Holger Gohlke, Noboru Mizushima, Björn Stork
Systematic analysis of ATG13 domain requirements for autophagy induction. Autophagy 14 (5) (2018)
Naonobu Fujita, Wilson Huang, Tzu-Han Lin, Jean-Francois Groulx, Steve Jean, Jen Nguyen, Yoshihiko Kuchitsu, Ikuko Koyama-Honda, Noboru Mizushima, Mitsunori Fukuda, Amy A Kiger
Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy. eLife 6 (2017)
Lorenzo Galluzzi, Eric H Baehrecke, Andrea Balabio, Patricia Boya, José Manuel Bravo-San Pedro, Francesco Cecconi, Augustine M Choi, Charleen T Chu, Patrice Codogno, Maria Isabel Colombo, Ana Maria Cuervo, Jayanta Debnath, Vojo P Deretic, Ivan Đikić, Eeva-Liisa Eskelinen, Gian Maria Fimia, Simone Fulda, David A Gewirtz, Douglas R Green, Malene Hansen, J Wade Harper, Marja Jäättelä, Terje Johansen, Gábor Juhász, Alec C Kimmelman, Claudine Kraft, Nicholas T Ktistakis, Sharad Kumar, Beth Levine, Carlos Lopez-Otin, Frank Madeo, Sascha Martens, Jennifer Martinez, Alicia Melendez, Noboru Mizushima, Christian Münz, Leon O Murphy, Josef M Penninger, Mauro Piacentini, Fulvio M Reggiori, David C Rubinsztein, Kevin M Ryan, Laura Santambrogio, Luca Scorrano, Anna Katharina Simon, Hans-Uwe Simon, Anne Simonsen, Nektarios Tavernarakis, Sharon A Tooze, Tamotsu Yoshimori, Junying Yuan, Zhenyu Yue, Qing Zhong, Guido Kroemer
Molecular definitions of autophagy and related processes. The EMBO journal 36 (13) (2017)
Taki Nishimura, Noboru Mizushima
The ULK complex initiates autophagosome formation at phosphatidylinositol synthase-enriched ER subdomains. Autophagy 13 (10) (2017)
Akiko Kuma, Masaaki Komatsu, Noboru Mizushima
Autophagy-monitoring and autophagy-deficient mice. Autophagy 13 (10) (2017)
Taki Nishimura, Norito Tamura, Nozomu Kono, Yuta Shimanaka, Hiroyuki Arai, Hayashi Yamamoto, Noboru Mizushima
Autophagosome formation is initiated at phosphatidylinositol synthase-enriched ER subdomains. The EMBO journal 36 (12) (2017)

Noboru Mizushima.css-eqlu8i{font-size:small;padding-left:4px;} (Noboru MIzushima)

Publication Activity (10 Years)

Top Topics

Top Venues

Noboru Mizushima (Noboru MIzushima)