Oliver Thorn-Seshold (O Thorn-Seshold)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 40

Top Venues

Journal of the American Chemical Society

Angewandte Chemie (International ed. in English)

JACS Au

Communications biology

Ludwig Maximilian University of Munich

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Ludwig Maximilian University of Munich

Germany

PI :: Dept Pharmacy

Ludwig Maximilian University of Munich

Germany

Postdoc :: Dept Chemistry

Publications

Philipp Mauker, Daniela Beckmann, Annabel Kitowski, Constanze Heise, Chantal Wientjens, Andrew J Davidson, Simone Wanderoy, Gabin Fabre, Angelika B Harbauer, Will Wood, Christoph Wilhelm, Julia Ahlfeld, Thomas Misgeld, Martin Kerschensteiner, Oliver Thorn-Seshold
Fluorogenic Chemical Probes for Wash-free Imaging of Cell Membrane Damage in Ferroptosis, Necrosis, and Axon Injury. Journal of the American Chemical Society (2024)
Lukas Zeisel, Jan G Felber, Karoline C Scholzen, Carina Schmitt, Alexander J Wiegand, Leonid Komissarov, Elias S J Arnér, Oliver Thorn-Seshold
Piperazine-Fused Cyclic Disulfides Unlock High-Performance Bioreductive Probes of Thioredoxins and Bifunctional Reagents for Thiol Redox Biology. Journal of the American Chemical Society 146 (8) (2024)
Lukas Zeisel, Jan G Felber, Karoline C Scholzen, Carina Schmitt, Alexander J Wiegand, Leonid Komissarov, Elias S J Arnér, Oliver Thorn-Seshold
Piperazine-Fused Cyclic Disulfides Unlock High-Performance Bioreductive Probes of Thioredoxins and Bifunctional Reagents for Thiol Redox Biology. Journal of the American Chemical Society 146 (8) (2024)
Lukas Zeisel, Jan G Felber, Karoline C Scholzen, Carina Schmitt, Alexander J Wiegand, Leonid Komissarov, Elias S J Arnér, Oliver Thorn-Seshold
Piperazine-Fused Cyclic Disulfides Unlock High-Performance Bioreductive Probes of Thioredoxins and Bifunctional Reagents for Thiol Redox Biology. Journal of the American Chemical Society 146 (8) (2024)
Martin Reynders, Małgorzata Garścia, Adrian Müller-Deku, Maximilian Wranik, Kristina Krauskopf, Luis de la Osa de la Rosa, Konstantin Schaffer, Anna Jötten, Alexander Rode, Valentin Stierle, Yvonne Kraus, Benedikt Baumgartner, Ahmed Ali, Andrei Bubeneck, Trina Seal, Michel O Steinmetz, Philipp Paulitschke, Oliver Thorn-Seshold
A photo-SAR study of photoswitchable azobenzene tubulin-inhibiting antimitotics identifying a general method for near-quantitative photocontrol. Chemical science 15 (31) (2024)
Lukas Zeisel, Jan G Felber, Karoline C Scholzen, Carina Schmitt, Alexander J Wiegand, Leonid Komissarov, Elias S J Arnér, Oliver Thorn-Seshold
Piperazine-Fused Cyclic Disulfides Unlock High-Performance Bioreductive Probes of Thioredoxins and Bifunctional Reagents for Thiol Redox Biology. Journal of the American Chemical Society (2024)
Markus Müller, Nian Liu, Vipul Gujrati, Abha Valavalkar, Sean Hartmann, Pia Anzenhofer, Uwe Klemm, András Telek, Benjamin Dietzek-Ivanšić, Achim Hartschuh, Vasilis Ntziachristos, Oliver Thorn-Seshold
Merged Molecular Switches Excel as Optoacoustic Dyes: Azobenzene-Cyanines Are Loud and Photostable NIR Imaging Agents. Angewandte Chemie (International ed. in English) 63 (33) (2024)
Martin Reynders, Małgorzata Garścia, Adrian Müller-Deku, Maximilian Wranik, Kristina Krauskopf, Luis de la Osa de la Rosa, Konstantin Schaffer, Anna Jötten, Alexander Rode, Valentin Stierle, Yvonne Kraus, Benedikt Baumgartner, Ahmed Ali, Andrei Bubeneck, Trina Seal, Michel O Steinmetz, Philipp Paulitschke, Oliver Thorn-Seshold
A photo-SAR study of photoswitchable azobenzene tubulin-inhibiting antimitotics identifying a general method for near-quantitative photocontrol. Chemical science 15 (31) (2024)
Markus Müller, Nian Liu, Vipul Gujrati, Abha Valavalkar, Sean Hartmann, Pia Anzenhofer, Uwe Klemm, András Telek, Benjamin Dietzek-Ivanšić, Achim Hartschuh, Vasilis Ntziachristos, Oliver Thorn-Seshold
Merged Molecular Switches Excel as Optoacoustic Dyes: Azobenzene-Cyanines Are Loud and Photostable NIR Imaging Agents. Angewandte Chemie (International ed. in English) (2024)
Filipe Coelho, Saidbakhrom Saidjalolov, Dimitri Moreau, Oliver Thorn-Seshold, Stefan Matile
Inhibition of Cell Motility by Cell-Penetrating Dynamic Covalent Cascade Exchangers: Integrins Participate in Thiol-Mediated Uptake. JACS Au 3 (4) (2023)
Jan G Felber, Oliver Thorn-Seshold
Correction to "40 Years of Duocarmycins: A Graphical Structure/Function Review of Their Chemical Evolution, from SAR to Prodrugs and ADCs". JACS Au 3 (5) (2023)
Cecilia D Velasco, Rachel Santarella-Mellwig, Martin Schorb, Li Gao, Oliver Thorn-Seshold, Artur Llobet
Microtubule depolymerization contributes to spontaneous neurotransmitter release in vitro. Communications biology 6 (1) (2023)
Cecilia D Velasco, Rachel Santarella-Mellwig, Martin Schorb, Li Gao, Oliver Thorn-Seshold, Artur Llobet
Microtubule depolymerization contributes to spontaneous neurotransmitter release in vitro. Communications biology 6 (1) (2023)
Filipe Coelho, Saidbakhrom Saidjalolov, Dimitri Moreau, Oliver Thorn-Seshold, Stefan Matile
Inhibition of Cell Motility by Cell-Penetrating Dynamic Covalent Cascade Exchangers: Integrins Participate in Thiol-Mediated Uptake. JACS Au 3 (4) (2023)
Jan G Felber, Annabel Kitowski, Lukas Zeisel, Martin S Maier, Constanze Heise, Julia Ahlfeld, Oliver Thorn-Seshold
Cyclic Dichalcogenides Extend the Reach of Bioreductive Prodrugs to Harness Thiol/Disulfide Oxidoreductases: Applications to seco -Duocarmycins Targeting the Thioredoxin System. ACS central science 9 (4) (2023)
Jan G Felber, Annabel Kitowski, Lukas Zeisel, Martin S Maier, Constanze Heise, Julia Ahlfeld, Oliver Thorn-Seshold
Cyclic Dichalcogenides Extend the Reach of Bioreductive Prodrugs to Harness Thiol/Disulfide Oxidoreductases: Applications to seco -Duocarmycins Targeting the Thioredoxin System. ACS central science 9 (4) (2023)
Cecilia D Velasco, Rachel Santarella-Mellwig, Martin Schorb, Li Gao, Oliver Thorn-Seshold, Artur Llobet
Microtubule depolymerization contributes to spontaneous neurotransmitter release in vitro. Communications biology 6 (1) (2023)
Cecilia D Velasco, Rachel Santarella-Mellwig, Martin Schorb, Li Gao, Oliver Thorn-Seshold, Artur Llobet
Microtubule depolymerization contributes to spontaneous neurotransmitter release in vitro. Communications biology 6 (1) (2023)
Cecilia D Velasco, Rachel Santarella-Mellwig, Martin Schorb, Li Gao, Oliver Thorn-Seshold, Artur Llobet
Microtubule depolymerization contributes to spontaneous neurotransmitter release in vitro. Communications biology 6 (1) (2023)
Maximilian Wranik, Michal W Kepa, Emma V Beale, Daniel James, Quentin Bertrand, Tobias Weinert, Antonia Furrer, Hannah Louise Glover, Dardan Gashi, Melissa Carrillo, Yasushi Kondo, Robin T Stipp, Georgii Khusainov, Karol Nass, Dmitry Ozerov, Claudio Cirelli, Philip J M Johnson, Florian S N Dworkowski, John H Beale, Scott Stubbs, Thierry Zamofing, Marco Schneider, Kristina Krauskopf, Li Gao, Oliver Thorn-Seshold, Christoph Bostedt, Camila Bacellar, Michel O Steinmetz, Christopher J Milne, Joerg Standfuss
A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers. Nature communications 14 (1) (2023)
Li Gao, Joyce C M Meiring, Constanze Heise, Ankit Rai, Adrian Müller-Deku, Anna Akhmanova, Julia Ahlfeld, Oliver Thorn-Seshold
Photoswitchable Epothilone-Based Microtubule Stabilisers Allow GFP-Imaging-Compatible, Optical Control over the Microtubule Cytoskeleton. Angewandte Chemie (International ed. in English) 61 (10) (2022)
Li Gao, Yvonne Kraus, Andrea Stegner, Thomas Wein, Constanze Heise, Leonie von Brunn, Elena Fajardo-Ruiz, Julia Ahlfeld, Oliver Thorn-Seshold
Self-reporting styrylthiazolium photopharmaceuticals: mitochondrial localisation as well as SAR drive biological activity. Organic & biomolecular chemistry 20 (39) (2022)
Florian Küllmer, Nynke A Vepřek, Malgorzata Borowiak, Veselin Nasufović, Sebastian Barutzki, Oliver Thorn-Seshold, Hans-Dieter Arndt, Dirk H Trauner
Next Generation Opto-Jasplakinolides Enable Local Remodeling of Actin Networks. Angewandte Chemie (International ed. in English) 61 (48) (2022)
Jan G Felber, Oliver Thorn-Seshold
40 Years of Duocarmycins: A Graphical Structure/Function Review of Their Chemical Evolution, from SAR to Prodrugs and ADCs. JACS Au 2 (12) (2022)
Jan G Felber, Lena Poczka, Karoline C Scholzen, Lukas Zeisel, Martin S Maier, Sander Busker, Ulrike Theisen, Christina Brandstädter, Katja Becker, Elias S J Arnér, Julia Ahlfeld, Oliver Thorn-Seshold
Cyclic 5-membered disulfides are not selective substrates of thioredoxin reductase, but are opened nonspecifically. Nature communications 13 (1) (2022)
Li Gao, Joyce C M Meiring, Adam Varady, Iris E Ruider, Constanze Heise, Maximilian Wranik, Cecilia D Velasco, Jennifer A Taylor, Beatrice Terni, Tobias Weinert, Jörg Standfuss, Clemens C Cabernard, Artur Llobet, Michel O Steinmetz, Andreas R Bausch, Martin Distel, Julia Ahlfeld, Anna Akhmanova, Oliver Thorn-Seshold
In Vivo Photocontrol of Microtubule Dynamics and Integrity, Migration and Mitosis, by the Potent GFP-Imaging-Compatible Photoswitchable Reagents SBTubA4P and SBTub2M. Journal of the American Chemical Society 144 (12) (2022)
Adrian Müller-Deku, Oliver Thorn-Seshold
Exhaustive Catalytic ortho -Alkoxylation of Azobenzenes: Flexible Access to Functionally Diverse Yellow-Light-Responsive Photoswitches. The Journal of organic chemistry (2022)
Oliver Thorn-Seshold, Joyce C M Meiring
Photocontrolling Microtubule Dynamics with Photoswitchable Chemical Reagents. Methods in molecular biology (Clifton, N.J.) 2430 (2022)
James L Rushworth, Aditya Raymond Thawani, Elena Fajardo-Ruiz, Joyce C M Meiring, Constanze Heise, Andrew J P White, Anna Akhmanova, Jochen R Brandt, Oliver Thorn-Seshold, Matthew John Fuchter
[5]-Helistatins: Tubulin-Binding Helicenes with Antimitotic Activity. JACS Au 2 (11) (2022)
Markus Müller, Konstantin Niemeyer, Nicole Urban, Navin K Ojha, Frank Zufall, Trese Leinders-Zufall, Michael Schaefer, Oliver Thorn-Seshold
BTDAzo: A Photoswitchable TRPC5 Channel Activator. Angewandte Chemie (International ed. in English) 61 (36) (2022)
Jan G Felber, Oliver Thorn-Seshold
40 Years of Duocarmycins: A Graphical Structure/Function Review of Their Chemical Evolution, from SAR to Prodrugs and ADCs. JACS Au 2 (12) (2022)
Alexander Sailer, Joyce C M Meiring, Constanze Heise, Linda N Pettersson, Anna Akhmanova, Julia Ahlfeld, Oliver Thorn-Seshold
Pyrrole Hemithioindigo Antimitotics with Near-Quantitative Bidirectional Photoswitching that Photocontrol Cellular Microtubule Dynamics with Single-Cell Precision*. Angewandte Chemie (International ed. in English) 60 (44) (2021)
Jan G Felber, Lukas Zeisel, Lena Poczka, Karoline Scholzen, Sander Busker, Martin S Maier, Ulrike Theisen, Christina Brandstädter, Katja Becker, Elias S J Arnér, Julia Ahlfeld, Oliver Thorn-Seshold
Selective, Modular Probes for Thioredoxins Enabled by Rational Tuning of a Unique Disulfide Structure Motif. Journal of the American Chemical Society 143 (23) (2021)
Oliver Thorn-Seshold
Comment on "Photo-Controlled Reversible Microtubule Assembly Mediated by Paclitaxel-Modified Cyclodextrin". Angewandte Chemie (International ed. in English) 59 (20) (2020)
Adrian Müller-Deku, Joyce C M Meiring, Kristina Loy, Yvonne Kraus, Constanze Heise, Rebekkah Bingham, Klara I Jansen, Xiaoyi Qu, Francesca Bartolini, Lukas C Kapitein, Anna Akhmanova, Julia Ahlfeld, Dirk H Trauner, Oliver Thorn-Seshold
Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton. Nature communications 11 (1) (2020)
Alexander Sailer, Franziska Ermer, Yvonne Kraus, Rebekkah Bingham, Ferdinand H Lutter, Julia Ahlfeld, Oliver Thorn-Seshold
Potent hemithioindigo-based antimitotics photocontrol the microtubule cytoskeleton in cellulo. Beilstein journal of organic chemistry 16 (2020)
Malgorzata Borowiak, Florian Küllmer, Florian Gegenfurtner, Sebastian Peil, Veselin Nasufovic, Stefan Zahler, Oliver Thorn-Seshold, Dirk H Trauner, Hans-Dieter Arndt
Optical Manipulation of F-Actin with Photoswitchable Small Molecules. Journal of the American Chemical Society 142 (20) (2020)
Alexander Sailer, Franziska Ermer, Yvonne Kraus, Ferdinand H Lutter, Carsten Donau, Maximilian Bremerich, Julia Ahlfeld, Oliver Thorn-Seshold
Hemithioindigos for Cellular Photopharmacology: Desymmetrised Molecular Switch Scaffolds Enabling Design Control over the Isomer-Dependency of Potent Antimitotic Bioactivity. Chembiochem : a European journal of chemical biology 20 (10) (2019)
Jennifer Zenker, Melanie D White, Rachel M Templin, Robert G Parton, Oliver Thorn-Seshold, S Bissiere, Nicolas Plachta
A microtubule-organizing center directing intracellular transport in the early mouse embryo. Science (New York, N.Y.) 357 (6354) (2018)
Kohgaku Eguchi, Zacharie Taoufiq, Oliver Thorn-Seshold, Dirk H Trauner, Masato Hasegawa, Tomoyuki Takahashi
Wild-Type Monomeric α-Synuclein Can Impair Vesicle Endocytosis and Synaptic Fidelity via Tubulin Polymerization at the Calyx of Held. The Journal of neuroscience : the official journal of the Society for Neuroscience 37 (25) (2017)

Oliver Thorn-Seshold.css-eqlu8i{font-size:small;padding-left:4px;} (O Thorn-Seshold)

Publication Activity (10 Years)

Top Topics

Top Venues

Oliver Thorn-Seshold (O Thorn-Seshold)