Olga I Lavrik (Olga Lavrik, Olga D Zakharova)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 76

Top Topics

Amyotrophic Lateral Sclerosis

Structure Activity Relationship

Top Venues

International journal of molecular sciences

Molecules (Basel, Switzerland)

This page only lists publications with an associated author ORCID identifier.

Publications

Svetlana N Khodyreva, Ekaterina S Ilina, Nadezhda S Dyrkheeva, Alina S Kochetkova, Alexandra A Yamskikh, Ekaterina A Maltseva, Anastasia A Malakhova, Sergey P Medvedev, Suren M Zakian, Olga I Lavrik
A Knockout of Poly(ADP-Ribose) Polymerase 1 in a Human Cell Line: An Influence on Base Excision Repair Reactions in Cellular Extracts. Cells 13 (4) (2024)
Oksana V Salomatina, Tatyana E Kornienko, Alexandra L Zakharenko, Nina I Komarova, Chigozie Achara, Jóhannes Reynisson, Nariman F Salakhutdinov, Olga I Lavrik, Konstantin P Volcho
New Dual Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 and 2 Based on Deoxycholic Acid: Design, Synthesis, Cytotoxicity, and Molecular Modeling. Molecules (Basel, Switzerland) 29 (3) (2024)
Oksana V Salomatina, Tatyana E Kornienko, Alexandra L Zakharenko, Nina I Komarova, Chigozie Achara, Jóhannes Reynisson, Nariman F Salakhutdinov, Olga I Lavrik, Konstantin P Volcho
New Dual Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 and 2 Based on Deoxycholic Acid: Design, Synthesis, Cytotoxicity, and Molecular Modeling. Molecules (Basel, Switzerland) 29 (3) (2024)
Svetlana N Khodyreva, Ekaterina S Ilina, Nadezhda S Dyrkheeva, Alina S Kochetkova, Alexandra A Yamskikh, Ekaterina A Maltseva, Anastasia A Malakhova, Sergey P Medvedev, Suren M Zakian, Olga I Lavrik
A Knockout of Poly(ADP-Ribose) Polymerase 1 in a Human Cell Line: An Influence on Base Excision Repair Reactions in Cellular Extracts. Cells 13 (4) (2024)
Oksana V Salomatina, Tatyana E Kornienko, Alexandra L Zakharenko, Nina I Komarova, Chigozie Achara, Jóhannes Reynisson, Nariman F Salakhutdinov, Olga I Lavrik, Konstantin P Volcho
New Dual Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 and 2 Based on Deoxycholic Acid: Design, Synthesis, Cytotoxicity, and Molecular Modeling. Molecules (Basel, Switzerland) 29 (3) (2024)
Natalia A Lebedeva, Nadezhda S Dyrkheeva, Nadejda I Rechkunova, Olga I Lavrik
Apurinic/apyrimidinic endonuclease 1 has major impact in prevention of suicidal covalent DNA-protein crosslink with apurinic/apyrimidinic site in cellular extracts. IUBMB life (2024)
Maria V Sukhanova, Rashid O Anarbaev, Ekaterina A Maltseva, Mikhail M Kutuzov, Olga I Lavrik
Divalent and multivalent cations control liquid-like assembly of poly(ADP-ribosyl)ated PARP1 into multimolecular associates in vitro. Communications biology 7 (1) (2024)
Tatyana E Kornienko, Arina A Chepanova, Alexandra L Zakharenko, Aleksandr S Filimonov, Olga A Luzina, Nadezhda S Dyrkheeva, Valeriy P Nikolin, Nelly A Popova, Nariman F Salakhutdinov, Olga I Lavrik
Enhancement of the Antitumor and Antimetastatic Effect of Topotecan and Normalization of Blood Counts in Mice with Lewis Carcinoma by Tdp1 Inhibitors-New Usnic Acid Derivatives. International journal of molecular sciences 25 (2) (2024)
Natalia A Lebedeva, Rashid O Anarbaev, Ekaterina A Maltseva, Maria V Sukhanova, Nadejda I Rechkunova, Olga I Lavrik
DNA Repair Protein XRCC1 Stimulates Activity of DNA Polymerase λ under Conditions of Microphase Separation. International journal of molecular sciences 25 (13) (2024)
Svetlana N Khodyreva, Ekaterina S Ilina, Nadezhda S Dyrkheeva, Alina S Kochetkova, Alexandra A Yamskikh, Ekaterina A Maltseva, Anastasia A Malakhova, Sergey P Medvedev, Suren M Zakian, Olga I Lavrik
A Knockout of Poly(ADP-Ribose) Polymerase 1 in a Human Cell Line: An Influence on Base Excision Repair Reactions in Cellular Extracts. Cells 13 (4) (2024)
Yuliya S Krasikova, Ekaterina A Maltseva, Svetlana N Khodyreva, Alexey N Evdokimov, Nadejda I Rechkunova, Olga I Lavrik
Does the XPA-FEN1 Interaction Concern to Nucleotide Excision Repair or Beyond? Biomolecules 14 (7) (2024)
Yuliya S Krasikova, Ekaterina A Maltseva, Svetlana N Khodyreva, Alexey N Evdokimov, Nadejda I Rechkunova, Olga I Lavrik
Does the XPA-FEN1 Interaction Concern to Nucleotide Excision Repair or Beyond? Biomolecules 14 (7) (2024)
Yuliya S Krasikova, Ekaterina A Maltseva, Svetlana N Khodyreva, Alexey N Evdokimov, Nadejda I Rechkunova, Olga I Lavrik
Does the XPA-FEN1 Interaction Concern to Nucleotide Excision Repair or Beyond? Biomolecules 14 (7) (2024)
Oksana V Salomatina, Tatyana E Kornienko, Alexandra L Zakharenko, Nina I Komarova, Chigozie Achara, Jóhannes Reynisson, Nariman F Salakhutdinov, Olga I Lavrik, Konstantin P Volcho
New Dual Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 and 2 Based on Deoxycholic Acid: Design, Synthesis, Cytotoxicity, and Molecular Modeling. Molecules (Basel, Switzerland) 29 (3) (2024)
Oksana V Salomatina, Tatyana E Kornienko, Alexandra L Zakharenko, Nina I Komarova, Chigozie Achara, Jóhannes Reynisson, Nariman F Salakhutdinov, Olga I Lavrik, Konstantin P Volcho
New Dual Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 and 2 Based on Deoxycholic Acid: Design, Synthesis, Cytotoxicity, and Molecular Modeling. Molecules (Basel, Switzerland) 29 (3) (2024)
Svetlana N Khodyreva, Ekaterina S Ilina, Nadezhda S Dyrkheeva, Alina S Kochetkova, Alexandra A Yamskikh, Ekaterina A Maltseva, Anastasia A Malakhova, Sergey P Medvedev, Suren M Zakian, Olga I Lavrik
A Knockout of Poly(ADP-Ribose) Polymerase 1 in a Human Cell Line: An Influence on Base Excision Repair Reactions in Cellular Extracts. Cells 13 (4) (2024)
Natalia A Lebedeva, Rashid O Anarbaev, Ekaterina A Maltseva, Maria V Sukhanova, Nadejda I Rechkunova, Olga I Lavrik
DNA Repair Protein XRCC1 Stimulates Activity of DNA Polymerase λ under Conditions of Microphase Separation. International journal of molecular sciences 25 (13) (2024)
Tatyana E Kornienko, Arina A Chepanova, Alexandra L Zakharenko, Aleksandr S Filimonov, Olga A Luzina, Nadezhda S Dyrkheeva, Valeriy P Nikolin, Nelly A Popova, Nariman F Salakhutdinov, Olga I Lavrik
Enhancement of the Antitumor and Antimetastatic Effect of Topotecan and Normalization of Blood Counts in Mice with Lewis Carcinoma by Tdp1 Inhibitors-New Usnic Acid Derivatives. International journal of molecular sciences 25 (2) (2024)
Svetlana N Khodyreva, Ekaterina S Ilina, Nadezhda S Dyrkheeva, Alina S Kochetkova, Alexandra A Yamskikh, Ekaterina A Maltseva, Anastasia A Malakhova, Sergey P Medvedev, Suren M Zakian, Olga I Lavrik
A Knockout of Poly(ADP-Ribose) Polymerase 1 in a Human Cell Line: An Influence on Base Excision Repair Reactions in Cellular Extracts. Cells 13 (4) (2024)
Alexander Ukraintsev, Mikhail Kutuzov, Ekaterina Belousova, Marie Joyeau, Victor M Golyshev, Alexander A Lomzov, Olga I Lavrik
PARP3 Affects Nucleosome Compaction Regulation. International journal of molecular sciences 24 (10) (2023)
Alexandra L Zakharenko, Olga A Luzina, Arina A Chepanova, Nadezhda S Dyrkheeva, Nariman F Salakhutdinov, Olga I Lavrik
Natural Products and Their Derivatives as Inhibitors of the DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1. International journal of molecular sciences 24 (6) (2023)
Konstantin P Volcho, Olga I Lavrik
Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach. International journal of molecular sciences 24 (9) (2023)
Nadezhda S Dyrkheeva, Anastasia A Malakhova, Aleksandra L Zakharenko, Larisa S Okorokova, Dmitriy N Shtokalo, Sophia V Pavlova, Sergey P Medvedev, Suren M Zakian, Anna A Nushtaeva, Alexey E Tupikin, Marsel Rasimovich Kabilov, Svetlana N Khodyreva, Olga A Luzina, Nariman F Salakhutdinov, Olga I Lavrik
Transcriptomic Analysis of CRISPR/Cas9-Mediated PARP1-Knockout Cells under the Influence of Topotecan and TDP1 Inhibitor. International journal of molecular sciences 24 (6) (2023)
Nadezhda S Dyrkheeva, Anastasia A Malakhova, Aleksandra L Zakharenko, Larisa S Okorokova, Dmitriy N Shtokalo, Sophia V Pavlova, Sergey P Medvedev, Suren M Zakian, Anna A Nushtaeva, Alexey E Tupikin, Marsel Rasimovich Kabilov, Svetlana N Khodyreva, Olga A Luzina, Nariman F Salakhutdinov, Olga I Lavrik
Transcriptomic Analysis of CRISPR/Cas9-Mediated PARP1-Knockout Cells under the Influence of Topotecan and TDP1 Inhibitor. International journal of molecular sciences 24 (6) (2023)
Dmitry I Ivankin, Tatyana E Kornienko, Marina A Mikhailova, Nadezhda S Dyrkheeva, Alexandra L Zakharenko, Chigozie Achara, Jóhannes Reynisson, Victor M Golyshev, Olga A Luzina, Konstantin P Volcho, Nariman F Salakhutdinov, Olga I Lavrik
Novel TDP1 Inhibitors: Disubstituted Thiazolidine-2,4-Diones Containing Monoterpene Moieties. International journal of molecular sciences 24 (4) (2023)
Ekaterina A Maltseva, Inna A Vasil'eva, Nina A Moor, Daria V Kim, Nadezhda S Dyrkheeva, Mikhail M Kutuzov, Ivan P Vokhtantsev, Lilya M Kulishova, Dmitry O Zharkov, Olga I Lavrik
Cas9 is mostly orthogonal to human systems of DNA break sensing and repair. PloS one 18 (11) (2023)
Dmitry I Ivankin, Tatyana E Kornienko, Marina A Mikhailova, Nadezhda S Dyrkheeva, Alexandra L Zakharenko, Chigozie Achara, Jóhannes Reynisson, Victor M Golyshev, Olga A Luzina, Konstantin P Volcho, Nariman F Salakhutdinov, Olga I Lavrik
Novel TDP1 Inhibitors: Disubstituted Thiazolidine-2,4-Diones Containing Monoterpene Moieties. International journal of molecular sciences 24 (4) (2023)
Konstantin P Volcho, Olga I Lavrik
Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach. International journal of molecular sciences 24 (9) (2023)
Vladlena S Makeeva, Nadezhda S Dyrkheeva, Olga I Lavrik, Suren M Zakian, Anastasia A Malakhova
Mutant-Huntingtin Molecular Pathways Elucidate New Targets for Drug Repurposing. International journal of molecular sciences 24 (23) (2023)
Alexandra L Zakharenko, Olga A Luzina, Arina A Chepanova, Nadezhda S Dyrkheeva, Nariman F Salakhutdinov, Olga I Lavrik
Natural Products and Their Derivatives as Inhibitors of the DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1. International journal of molecular sciences 24 (6) (2023)
Dmitry I Ivankin, Tatyana E Kornienko, Marina A Mikhailova, Nadezhda S Dyrkheeva, Alexandra L Zakharenko, Chigozie Achara, Jóhannes Reynisson, Victor M Golyshev, Olga A Luzina, Konstantin P Volcho, Nariman F Salakhutdinov, Olga I Lavrik
Novel TDP1 Inhibitors: Disubstituted Thiazolidine-2,4-Diones Containing Monoterpene Moieties. International journal of molecular sciences 24 (4) (2023)
Nadezhda S Dyrkheeva, Anastasia A Malakhova, Aleksandra L Zakharenko, Larisa S Okorokova, Dmitriy N Shtokalo, Sophia V Pavlova, Sergey P Medvedev, Suren M Zakian, Anna A Nushtaeva, Alexey E Tupikin, Marsel Rasimovich Kabilov, Svetlana N Khodyreva, Olga A Luzina, Nariman F Salakhutdinov, Olga I Lavrik
Transcriptomic Analysis of CRISPR/Cas9-Mediated PARP1-Knockout Cells under the Influence of Topotecan and TDP1 Inhibitor. International journal of molecular sciences 24 (6) (2023)
Alexandra L Zakharenko, Olga A Luzina, Arina A Chepanova, Nadezhda S Dyrkheeva, Nariman F Salakhutdinov, Olga I Lavrik
Natural Products and Their Derivatives as Inhibitors of the DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1. International journal of molecular sciences 24 (6) (2023)
Dmitry I Ivankin, Tatyana E Kornienko, Marina A Mikhailova, Nadezhda S Dyrkheeva, Alexandra L Zakharenko, Chigozie Achara, Jóhannes Reynisson, Victor M Golyshev, Olga A Luzina, Konstantin P Volcho, Nariman F Salakhutdinov, Olga I Lavrik
Novel TDP1 Inhibitors: Disubstituted Thiazolidine-2,4-Diones Containing Monoterpene Moieties. International journal of molecular sciences 24 (4) (2023)
Dmitry I Ivankin, Tatyana E Kornienko, Marina A Mikhailova, Nadezhda S Dyrkheeva, Alexandra L Zakharenko, Chigozie Achara, Jóhannes Reynisson, Victor M Golyshev, Olga A Luzina, Konstantin P Volcho, Nariman F Salakhutdinov, Olga I Lavrik
Novel TDP1 Inhibitors: Disubstituted Thiazolidine-2,4-Diones Containing Monoterpene Moieties. International journal of molecular sciences 24 (4) (2023)
Alexandra L Zakharenko, Nadezhda S Dyrkheeva, Olga A Luzina, Aleksandr S Filimonov, Evgenii S Mozhaitsev, Anastasia A Malakhova, Sergey P Medvedev, Suren M Zakian, Nariman F Salakhutdinov, Olga I Lavrik
Usnic Acid Derivatives Inhibit DNA Repair Enzymes Tyrosyl-DNA Phosphodiesterases 1 and 2 and Act as Potential Anticancer Agents. Genes 14 (10) (2023)
Dmitry I Ivankin, Tatyana E Kornienko, Marina A Mikhailova, Nadezhda S Dyrkheeva, Alexandra L Zakharenko, Chigozie Achara, Jóhannes Reynisson, Victor M Golyshev, Olga A Luzina, Konstantin P Volcho, Nariman F Salakhutdinov, Olga I Lavrik
Novel TDP1 Inhibitors: Disubstituted Thiazolidine-2,4-Diones Containing Monoterpene Moieties. International journal of molecular sciences 24 (4) (2023)
Tatyana M Khomenko, Alexandra L Zakharenko, Tatyana E Kornienko, Arina A Chepanova, Nadezhda S Dyrkheeva, Anastasia O Artemova, Dina V Korchagina, Chigozie Achara, Anthony Curtis, Jóhannes Reynisson, Konstantin P Volcho, Nariman F Salakhutdinov, Olga I Lavrik
New 5-Hydroxycoumarin-Based Tyrosyl-DNA Phosphodiesterase I Inhibitors Sensitize Tumor Cell Line to Topotecan. International journal of molecular sciences 24 (11) (2023)
Anastasia S Singatulina, Maria V Sukhanova, Bénédicte Desforges, Vandana Joshi, David Pastré, Olga I Lavrik
PARP1 Activation Controls Stress Granule Assembly after Oxidative Stress and DNA Damage. Cells 11 (23) (2022)
Aldar A Munkuev, Nadezhda S Dyrkheeva, Tatyana E Kornienko, Ekaterina S Ilina, Dmitry I Ivankin, Evgenii V Suslov, Dina V Korchagina, Yuriy V Gatilov, Alexandra L Zakharenko, Anastasia A Malakhova, Jóhannes Reynisson, Konstantin P Volcho, Nariman F Salakhutdinov, Olga I Lavrik
Adamantane-Monoterpenoid Conjugates Linked via Heterocyclic Linkers Enhance the Cytotoxic Effect of Topotecan. Molecules (Basel, Switzerland) 27 (11) (2022)
Maria V Sukhanova, Rashid O Anarbaev, Ekaterina A Maltseva, David Pastré, Olga I Lavrik
FUS Microphase Separation: Regulation by Nucleic Acid Polymers and DNA Repair Proteins. International journal of molecular sciences 23 (21) (2022)
Yuliya S Krasikova, Olga I Lavrik, Nadejda I Rechkunova
The XPA Protein-Life under Precise Control. Cells 11 (23) (2022)
Yuliya S Krasikova, Olga I Lavrik, Nadejda I Rechkunova
The XPA Protein-Life under Precise Control. Cells 11 (23) (2022)
Yuliya S Krasikova, Olga I Lavrik, Nadejda I Rechkunova
The XPA Protein-Life under Precise Control. Cells 11 (23) (2022)
Anastasia S Singatulina, Maria V Sukhanova, Bénédicte Desforges, Vandana Joshi, David Pastré, Olga I Lavrik
PARP1 Activation Controls Stress Granule Assembly after Oxidative Stress and DNA Damage. Cells 11 (23) (2022)
Elizaveta E Alemasova, Olga I Lavrik
Poly(ADP-ribose) in Condensates: The PARtnership of Phase Separation and Site-Specific Interactions. International journal of molecular sciences 23 (22) (2022)
Yuliya S Krasikova, Olga I Lavrik, Nadejda I Rechkunova
The XPA Protein-Life under Precise Control. Cells 11 (23) (2022)
Irina A Chernyshova, Aleksandra L Zakharenko, Nikolay N Kurochkin, Nadezhda S Dyrkheeva, Tatyana E Kornienko, Nelly A Popova, Valeriy P Nikolin, Ekaterina S Ilina, Timofey D Zharkov, Maxim S Kupryushkin, Vladimir E Oslovsky, Mikhail S Drenichev, Olga I Lavrik
The Lipophilic Purine Nucleoside-Tdp1 Inhibitor-Enhances DNA Damage Induced by Topotecan In Vitro and Potentiates the Antitumor Effect of Topotecan In Vivo. Molecules (Basel, Switzerland) 28 (1) (2022)
Irina A Chernyshova, Aleksandra L Zakharenko, Nikolay N Kurochkin, Nadezhda S Dyrkheeva, Tatyana E Kornienko, Nelly A Popova, Valeriy P Nikolin, Ekaterina S Ilina, Timofey D Zharkov, Maxim S Kupryushkin, Vladimir E Oslovsky, Mikhail S Drenichev, Olga I Lavrik
The Lipophilic Purine Nucleoside-Tdp1 Inhibitor-Enhances DNA Damage Induced by Topotecan In Vitro and Potentiates the Antitumor Effect of Topotecan In Vivo. Molecules (Basel, Switzerland) 28 (1) (2022)
Irina A Chernyshova, Aleksandra L Zakharenko, Nikolay N Kurochkin, Nadezhda S Dyrkheeva, Tatyana E Kornienko, Nelly A Popova, Valeriy P Nikolin, Ekaterina S Ilina, Timofey D Zharkov, Maxim S Kupryushkin, Vladimir E Oslovsky, Mikhail S Drenichev, Olga I Lavrik
The Lipophilic Purine Nucleoside-Tdp1 Inhibitor-Enhances DNA Damage Induced by Topotecan In Vitro and Potentiates the Antitumor Effect of Topotecan In Vivo. Molecules (Basel, Switzerland) 28 (1) (2022)
Anastasia S Singatulina, Maria V Sukhanova, Bénédicte Desforges, Vandana Joshi, David Pastré, Olga I Lavrik
PARP1 Activation Controls Stress Granule Assembly after Oxidative Stress and DNA Damage. Cells 11 (23) (2022)
Anastasia S Singatulina, Maria V Sukhanova, Bénédicte Desforges, Vandana Joshi, David Pastré, Olga I Lavrik
PARP1 Activation Controls Stress Granule Assembly after Oxidative Stress and DNA Damage. Cells 11 (23) (2022)
Nadezhda S Dyrkheeva, Irina A Chernyshova, Georgy A Ivanov, Yuri B Porozov, Anastasia A Zenchenko, Vladimir E Oslovsky, Alexandra L Zakharenko, Darina I Nasyrova, Galina N Likhatskaya, Sergey N Mikhailov, Olga I Lavrik, Mikhail S Drenichev
In Vitro and In Silico Studies of Human Tyrosyl-DNA Phosphodiesterase 1 (Tdp1) Inhibition by Stereoisomeric Forms of Lipophilic Nucleosides: The Role of Carbohydrate Stereochemistry in Ligand-Enzyme Interactions. Molecules (Basel, Switzerland) 27 (8) (2022)
Elizaveta E Alemasova, Olga I Lavrik
A sePARate phase? Poly(ADP-ribose) versus RNA in the organization of biomolecular condensates. Nucleic acids research 50 (19) (2022)
Tatyana A Kurgina, Nina A Moor, Mikhail M Kutuzov, Konstantin N Naumenko, Alexander A Ukraintsev, Olga I Lavrik
Dual function of HPF1 in the modulation of PARP1 and PARP2 activities. Communications biology 4 (1) (2021)
Nadezhda S Dyrkheeva, Aleksandr S Filimonov, Olga A Luzina, Alexandra L Zakharenko, Ekaterina S Ilina, Anastasia A Malakhova, Sergey P Medvedev, Jóhannes Reynisson, Konstantin P Volcho, Suren M Zakian, Nariman F Salakhutdinov, Olga I Lavrik
New Hybrid Compounds Combining Fragments of Usnic Acid and Monoterpenoids for Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibition. Biomolecules 11 (7) (2021)
Inna Vasil'eva, Nina Moor, Rashid Anarbaev, Mikhail Kutuzov, Olga I Lavrik
Functional Roles of PARP2 in Assembling Protein-Protein Complexes Involved in Base Excision DNA Repair. International journal of molecular sciences 22 (9) (2021)
Yuliya Krasikova, Nadejda Rechkunova, Olga I Lavrik
Nucleotide Excision Repair: From Molecular Defects to Neurological Abnormalities. International journal of molecular sciences 22 (12) (2021)
Kseniya S Kovaleva, Olga I Yarovaya, Konstantin Ponomarev, Sergey V Cheresiz, Amirhossein Azimirad, Irina Chernyshova, Alexandra Zakharenko, Vasily Konev, Tatiana Khlebnikova, Evgenii Mozhaytsev, Evgenii V Suslov, Dmitry K Nilov, Vytas K Švedas, Andrey Pokrovsky, Olga I Lavrik, Nariman Salakhutdinov
Design, Synthesis, and Molecular Docking Study of New Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Inhibitors Combining Resin Acids and Adamantane Moieties. Pharmaceuticals (Basel, Switzerland) 14 (5) (2021)
Oksana V Salomatina, Nadezhda S Dyrkheeva, Irina I Popadyuk, Alexandra L Zakharenko, Ekaterina S Ilina, Nina I Komarova, Jóhannes Reynisson, Nariman F Salakhutdinov, Olga I Lavrik, Konstantin P Volcho
New Deoxycholic Acid Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitors Also Inhibit Tyrosyl-DNA Phosphodiesterase 2. Molecules (Basel, Switzerland) 27 (1) (2021)
Elizaveta D Gladkova, Arina A Chepanova, Ekaterina S Ilina, Alexandra L Zakharenko, Jóhannes Reynisson, Olga A Luzina, Konstantin P Volcho, Olga I Lavrik, Nariman F Salakhutdinov
Discovery of Novel Sultone Fused Berberine Derivatives as Promising Tdp1 Inhibitors. Molecules (Basel, Switzerland) 26 (7) (2021)
Nadezhda S Dyrkheeva, Aleksandr S Filimonov, Olga A Luzina, Kristina A Orlova, Irina A Chernyshova, Tatyana E Kornienko, Anastasia A Malakhova, Sergey P Medvedev, Alexandra L Zakharenko, Ekaterina S Ilina, Rashid O Anarbaev, Konstantin N Naumenko, Kristina V Klabenkova, Ekaterina A Burakova, Dmitry A Stetsenko, Suren M Zakian, Nariman F Salakhutdinov, Olga I Lavrik
New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1. International journal of molecular sciences 22 (21) (2021)
Aldar A Munkuev, Evgenii S Mozhaitsev, Arina A Chepanova, Evgenii V Suslov, Dina V Korchagina, Olga D Zakharova, Ekaterina S Ilina, Nadezhda S Dyrkheeva, Alexandra L Zakharenko, Jóhannes Reynisson, Konstantin P Volcho, Nariman F Salakhutdinov, Olga I Lavrik
Novel Tdp1 Inhibitors Based on Adamantane Connected with Monoterpene Moieties via Heterocyclic Fragments. Molecules (Basel, Switzerland) 26 (11) (2021)
Elizaveta D Gladkova, Ivan V Nechepurenko, Roman A Bredikhin, Arina A Chepanova, Alexandra L Zakharenko, Olga A Luzina, Ekaterina S Ilina, Nadezhda S Dyrkheeva, Evgeniya M Mamontova, Rashid O Anarbaev, Jóhannes Reynisson, Konstantin P Volcho, Nariman F Salakhutdinov, Olga I Lavrik
The First Berberine-Based Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), an Important DNA Repair Enzyme. International journal of molecular sciences 21 (19) (2020)
Alexandra L Zakharenko, Mikhail S Drenichev, Nadezhda S Dyrkheeva, Georgy A Ivanov, Vladimir E Oslovsky, Ekaterina S Ilina, Irina A Chernyshova, Olga I Lavrik, Sergey N Mikhailov
Inhibition of Tyrosyl-DNA Phosphodiesterase 1 by Lipophilic Pyrimidine Nucleosides. Molecules (Basel, Switzerland) 25 (16) (2020)
Olga Luzina, Alexander Filimonov, Alexandra Zakharenko, Arina Chepanova, Olga Zakharova, Ekaterina Ilina, Nadezhda Dyrkheeva, Galina Likhatskaya, Nariman Salakhutdinov, Olga I Lavrik
Usnic Acid Conjugates with Monoterpenoids as Potent Tyrosyl-DNA Phosphodiesterase 1 Inhibitors. Journal of natural products 83 (8) (2020)
Dmitry K Nilov, Natalya Maluchenko, Tatyana Kurgina, Sergey Pushkarev, Alexandra Lys, Mikhail Kutuzov, Nadezhda S Gerasimova, Alexey Feofanov, Vytas K Švedas, Olga I Lavrik, Vasily M Studitsky
Molecular Mechanisms of PARP-1 Inhibitor 7-Methylguanine. International journal of molecular sciences 21 (6) (2020)
Irina V Il'ina, Nadezhda S Dyrkheeva, Alexandra L Zakharenko, Alexander Yu Sidorenko, Nikolay S Li-Zhulanov, Dina V Korchagina, Raina Chand, Daniel M Ayine-Tora, Arina A Chepanova, Olga D Zakharova, Ekaterina S Ilina, Jóhannes Reynisson, Anastasia A Malakhova, Sergey P Medvedev, Suren M Zakian, Konstantin P Volcho, Nariman F Salakhutdinov, Olga I Lavrik
Design, Synthesis, and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1. Molecules (Basel, Switzerland) 25 (15) (2020)
Maria V Sukhanova, Anastasia S Singatulina, David Pastré, Olga I Lavrik
Fused in Sarcoma (FUS) in DNA Repair: Tango with Poly(ADP-ribose) Polymerase 1 and Compartmentalisation of Damaged DNA. International journal of molecular sciences 21 (19) (2020)
Nadejda I Rechkunova, Olga I Lavrik
Photoreactive DNA as a Tool to Study Replication Protein A Functioning in DNA Replication and Repair. Photochemistry and photobiology 96 (2) (2020)
Elizaveta O Boldinova, Ekaterina A Belousova, Diana I Gagarinskaya, Ekaterina A Maltseva, Svetlana N Khodyreva, Olga I Lavrik, Alena V Makarova
Strand Displacement Activity of PrimPol. International journal of molecular sciences 21 (23) (2020)
Nina Moor, Inna Vasil'eva, Olga I Lavrik
Functional Role of N-Terminal Extension of Human AP Endonuclease 1 In Coordination of Base Excision DNA Repair via Protein-Protein Interactions. International journal of molecular sciences 21 (9) (2020)
Konstantin N Naumenko, Mariya V Sukhanova, Loic Hamon, Tatyana A Kurgina, Elizaveta E Alemasova, Mikhail M Kutuzov, David Pastré, Olga I Lavrik
Regulation of Poly(ADP-Ribose) Polymerase 1 Activity by Y-Box-Binding Protein 1. Biomolecules 10 (9) (2020)
Alexandra Zakharenko, Nadezhda Dyrkheeva, Olga I Lavrik
Dual DNA topoisomerase 1 and tyrosyl-DNA phosphodiesterase 1 inhibition for improved anticancer activity. Medicinal research reviews 39 (4) (2019)
Anastasia O Komarova, Mikhail S Drenichev, Nadezhda S Dyrkheeva, Irina V Kulikova, Vladimir E Oslovsky, Olga I Lavrik, Alexandra L Zakharenko, Sergey N Mikhailov, Olga I Lavrik
Novel group of tyrosyl-DNA-phosphodiesterase 1 inhibitors based on disaccharide nucleosides as drug prototypes for anti-cancer therapy. Journal of enzyme inhibition and medicinal chemistry 33 (1) (2018)
Yuliya S Krasikova, Nadejda I Rechkunova, Ekaterina A Maltseva, Olga I Lavrik
RPA and XPA interaction with DNA structures mimicking intermediates of the late stages in nucleotide excision repair. PloS one 13 (1) (2018)