Osamu Kurasawa

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2021
Publications (10 Years): 3

Top Topics

Human Immunodeficiency Virus

Top Venues

Science advances

Journal of medicinal chemistry

Axcelead Drug Discovery Partners

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Axcelead Drug Discovery Partners Jul 01 2017

Japan

Principal Scientist :: Research

Takeda Pharmaceutical Company Apr 01 1998 - Jun 30 2017

Japan

Principal Scientist :: Research

Publications

Kenichi Iwai, Tadahiro Nambu, Yukie Kashima, Jie Yu, Kurt Y Eng, Kazumasa Miyamoto, Kazuyo Kakoi, Masamitsu Gotou, Toshiyuki Takeuchi, Akifumi Kogame, Jessica Sappal, Saomi Murai, Hiroshi Haeno, Shun-Ichiro Kageyama, Osamu Kurasawa, Huifeng Niu, Karuppiah Kannan, Akihiro Ohashi
A CDC7 inhibitor sensitizes DNA-damaging chemotherapies by suppressing homologous recombination repair to delay DNA damage recovery. Science advances 7 (21) (2021)
Osamu Kurasawa, Tohru Miyazaki, Misaki Homma, Yuya Oguro, Takashi Imada, Noriko Uchiyama, Kenichi Iwai, Yukiko Yamamoto, Momoko Ohori, Hideto Hara, Hiroshi Sugimoto, Kentaro Iwata, Robert Skene, Isaac Hoffman, Akihiro Ohashi, Toshiyuki Nomura, Nobuo Cho
Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-d]pyrimidinone-Based Cdc7 Inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active Investigational Antitumor Agent. Journal of medicinal chemistry 63 (3) (2020)
Kenichi Iwai, Tadahiro Nambu, Ryo Dairiki, Momoko Ohori, Jie Yu, Kristine Burke, Masamitsu Gotou, Yukiko Yamamoto, Shunsuke Ebara, Sachio Shibata, Ryosuke Hibino, Satoru Nishizawa, Tohru Miyazaki, Misaki Homma, Yuya Oguro, Takashi Imada, Nobuo Cho, Noriko Uchiyama, Akifumi Kogame, Toshiyuki Takeuchi, Osamu Kurasawa, Kazunori Yamanaka, Huifeng Niu, Akihiro Ohashi
Molecular mechanism and potential target indication of TAK-931, a novel CDC7-selective inhibitor. Science advances 5 (5) (2019)