Pak-Chung Sham (Pak Chung Sham, Pak C Sham, Pak Chung Sham)

Scopus Author ID ResearcherID HKU ResearcherPage ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 28

Top Topics

Genome Wide Association

Major Depressive Disorder

Top Venues

Nature communications

Psychological medicine

Genetic epidemiology

This page only lists publications with an associated author ORCID identifier.

Publications

Lane G Chen, Justin D Tubbs, Zipeng Liu, Thuan-Quoc Thach, Pak-Chung Sham
Mendelian randomization: causal inference leveraging genetic data. Psychological medicine (2024)
Kai Zhao, Sen Huang, Cuichan Lin, Pak-Chung Sham, Hon-Cheong So, Zhixiang Lin
INSIDER: Interpretable sparse matrix decomposition for RNA expression data analysis. PLoS genetics 20 (3) (2024)
Lane G Chen, Justin D Tubbs, Zipeng Liu, Thuan-Quoc Thach, Pak-Chung Sham
Mendelian randomization: causal inference leveraging genetic data. Psychological medicine 54 (8) (2024)
Lane G Chen, Justin D Tubbs, Zipeng Liu, Thuan-Quoc Thach, Pak-Chung Sham
Mendelian randomization: causal inference leveraging genetic data. Psychological medicine 54 (8) (2024)
Kai Zhao, Sen Huang, Cuichan Lin, Pak-Chung Sham, Hon-Cheong So, Zhixiang Lin
INSIDER: Interpretable sparse matrix decomposition for RNA expression data analysis. PLoS genetics 20 (3) (2024)
Kai Zhao, Sen Huang, Cuichan Lin, Pak-Chung Sham, Hon-Cheong So, Zhixiang Lin
INSIDER: Interpretable sparse matrix decomposition for RNA expression data analysis. PLoS genetics 20 (3) (2024)
Kai Zhao, Sen Huang, Cuichan Lin, Pak-Chung Sham, Hon-Cheong So, Zhixiang Lin
INSIDER: Interpretable sparse matrix decomposition for RNA expression data analysis. PLoS genetics 20 (3) (2024)
Zhao Wang, Qian Liang, Xinyi Qian, Bolang Hu, Zhanye Zheng, Jianhua Wang, Yuelin Hu, Zhengkai Bao, Ke Zhao, Yao Zhou, Xiangling Feng, Xianfu Yi, Jin Li, Jiandang Shi, Zhe Liu, Jihui Hao, Kexin Chen, Ying Yu, Pak-Chung Sham, Wange Lu, Xiaoyan Wang, Weihong Song, Mulin Jun Li
An autoimmune pleiotropic SNP modulates IRF5 alternative promoter usage through ZBTB3-mediated chromatin looping. Nature communications 14 (1) (2023)
Zipeng Liu, Yiming Qin, Tian Wu, Justin D Tubbs, Larry Baum, Timothy Shin Heng Mak, Miao-Xin Li, Yan Dora Zhang, Pak-Chung Sham
Reciprocal causation mixture model for robust Mendelian randomization analysis using genome-scale summary data. Nature communications 14 (1) (2023)
Zhao Wang, Qian Liang, Xinyi Qian, Bolang Hu, Zhanye Zheng, Jianhua Wang, Yuelin Hu, Zhengkai Bao, Ke Zhao, Yao Zhou, Xiangling Feng, Xianfu Yi, Jin Li, Jiandang Shi, Zhe Liu, Jihui Hao, Kexin Chen, Ying Yu, Pak-Chung Sham, Wange Lu, Xiaoyan Wang, Weihong Song, Mulin Jun Li
An autoimmune pleiotropic SNP modulates IRF5 alternative promoter usage through ZBTB3-mediated chromatin looping. Nature communications 14 (1) (2023)
Zipeng Liu, Yiming Qin, Tian Wu, Justin D Tubbs, Larry Baum, Timothy Shin Heng Mak, Miao-Xin Li, Yan Dora Zhang, Pak-Chung Sham
Reciprocal causation mixture model for robust Mendelian randomization analysis using genome-scale summary data. Nature communications 14 (1) (2023)
Zhao Wang, Qian Liang, Xinyi Qian, Bolang Hu, Zhanye Zheng, Jianhua Wang, Yuelin Hu, Zhengkai Bao, Ke Zhao, Yao Zhou, Xiangling Feng, Xianfu Yi, Jin Li, Jiandang Shi, Zhe Liu, Jihui Hao, Kexin Chen, Ying Yu, Pak-Chung Sham, Wange Lu, Xiaoyan Wang, Weihong Song, Mulin Jun Li
An autoimmune pleiotropic SNP modulates IRF5 alternative promoter usage through ZBTB3-mediated chromatin looping. Nature communications 14 (1) (2023)
Tracy L Warren, Justin D Tubbs, Tyler A Lesh, Mylena B Corona, Sarvenaz Pakzad, Marina Albuquerque, Praveena Singh, Vanessa Zarubin, Sarah Morse, Pak-Chung Sham, Cameron S Carter, Alexander S Nord
Association of neurotransmitter pathway polygenic risk with specific symptom profiles in psychosis. medRxiv : the preprint server for health sciences (2023)
Zipeng Liu, Yiming Qin, Tian Wu, Justin D Tubbs, Larry Baum, Timothy Shin Heng Mak, Miao-Xin Li, Yan Dora Zhang, Pak-Chung Sham
Reciprocal causation mixture model for robust Mendelian randomization analysis using genome-scale summary data. Nature communications 14 (1) (2023)
Zhao Wang, Qian Liang, Xinyi Qian, Bolang Hu, Zhanye Zheng, Jianhua Wang, Yuelin Hu, Zhengkai Bao, Ke Zhao, Yao Zhou, Xiangling Feng, Xianfu Yi, Jin Li, Jiandang Shi, Zhe Liu, Jihui Hao, Kexin Chen, Ying Yu, Pak-Chung Sham, Wange Lu, Xiaoyan Wang, Weihong Song, Mulin Jun Li
An autoimmune pleiotropic SNP modulates IRF5 alternative promoter usage through ZBTB3-mediated chromatin looping. Nature communications 14 (1) (2023)
Zhao Wang, Qian Liang, Xinyi Qian, Bolang Hu, Zhanye Zheng, Jianhua Wang, Yuelin Hu, Zhengkai Bao, Ke Zhao, Yao Zhou, Xiangling Feng, Xianfu Yi, Jin Li, Jiandang Shi, Zhe Liu, Jihui Hao, Kexin Chen, Ying Yu, Pak-Chung Sham, Wange Lu, Xiaoyan Wang, Weihong Song, Mulin Jun Li
An autoimmune pleiotropic SNP modulates IRF5 alternative promoter usage through ZBTB3-mediated chromatin looping. Nature communications 14 (1) (2023)
Justin D Tubbs, Perry B M Leung, Yuanxin Zhong, Na Zhan, Tomy C K Hui, Karen K Y Ho, Karen S Y Hung, Eric F C Cheung, Hon-Cheong So, Simon S Y Lui, Pak-Chung Sham
Pathway-Specific Polygenic Scores Improve Cross-Ancestry Prediction of Psychosis and Clinical Outcomes. medRxiv : the preprint server for health sciences (2023)
Zipeng Liu, Yiming Qin, Tian Wu, Justin D Tubbs, Larry Baum, Timothy Shin Heng Mak, Miao-Xin Li, Yan Dora Zhang, Pak-Chung Sham
Reciprocal causation mixture model for robust Mendelian randomization analysis using genome-scale summary data. Nature communications 14 (1) (2023)
Lai Ming Christy Hui, Andreas Kar Hin Wong, Elise Chun Ning Ho, Bertha Sze Ting Lam, Priscilla Wing Man Hui, Tiffany Junchen Tao, Candice Tze Kwan Kam, Sherry Kit Wa Chan, Edwin Ho Ming Lee, Suen Yi Nam, May Mei Ling Lam, Cindy Pui Yu Chiu, Frendi Wing Sai Li, Kwok Fai Leung, Sarah M McGhee, Chi Wing Law, Dicky Wai Sau Chung, Wai Song Yeung, Michael Gar Chung Yiu, Edwin Pui Fai Pang, Steve Tso, Simon Sai Yu Lui, Se Fong Hung, Wing King Lee, Ka Chee Yip, Ka Lik Kwan, Roger Man Kin Ng, Pak-Chung Sham, William G Honer, Eric Yu Hai Chen
Effectiveness and optimal duration of early intervention treatment in adult-onset psychosis: a randomized clinical trial. Psychological medicine (2022)
Saloni Dattani, Andrew M McIntosh, Cathryn M Lewis, Pak-Chung Sham
Clarifying the causes of consistent and inconsistent findings in genetics. Genetic epidemiology 46 (7) (2022)
Yong-Fei Wang, Yan Zhang, Zhiming Lin, Huoru Zhang, Ting-You Wang, Yujie Cao, David L Morris, Yujun Sheng, Xianyong Yin, Shi-Long Zhong, Xiaoqiong Gu, Yao Lei, Jing He, Qi Wu, Jiangshan Jane Shen, Jing Yang, Tai-Hing Lam, Jia-Huang Lin, Jim Zhiming Mai, Mengbiao Guo, Yuanjia Tang, Yanhui Chen, Qin Song, Bo Ban, Chi Chiu Mok, Yong Cui, Liangjing Lu, Nan Shen, Pak-Chung Sham, Wallace Chak Sing Lau, David K Smith, Timothy J Vyse, Xuejun Zhang, Yu Lung Lau, Wanling Yang
Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups. Nature communications 12 (1) (2021)
Frank Pui-Ling Lai, Zhixin Li, Tingwen Zhou, Adrian On Wah Leung, Sin-Ting Lau, Kathy Nga-Chu Lui, William Yu-Ming Wong, Pak-Chung Sham, Chi-Chung Hui, Elly Sau-Wai Ngan
Ciliary protein Kif7 regulates Gli and Ezh2 for initiating the neuronal differentiation of enteric neural crest cells during development. Science advances 7 (42) (2021)
Daniel Wai-Hung Ho, Yu-Man Tsui, Lo-Kong Chan, Karen Man-Fong Sze, Xin Zhang, Jacinth Wing-Sum Cheu, Yung-Tuen Chiu, Joyce Man-Fong Lee, Albert Chi-Yan Chan, Elaine Tin-Yan Cheung, Derek Tsz-Wai Yau, Nam-Hung Chia, Irene Lai-Oi Lo, Pak-Chung Sham, Tan-To Cheung, Carmen Chak-Lui Wong, Irene Oi Lin Ng
Single-cell RNA sequencing shows the immunosuppressive landscape and tumor heterogeneity of HBV-associated hepatocellular carcinoma. Nature communications 12 (1) (2021)
Xiaobao Dong, Dandan Huang, Xianfu Yi, Shijie Zhang, Zhao Wang, Bin Yan, Pak-Chung Sham, Kexin Chen, Mulin Jun Li
Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes. Communications biology 3 (1) (2020)
Liang-Dar Hwang, Justin D Tubbs, Justin Luong, Mischa Lundberg, Gunn-Helen Moen, Geng Wang, Nicole M Warrington, Pak-Chung Sham, Gabriel Cuellar-Partida, David M Evans
Estimating indirect parental genetic effects on offspring phenotypes using virtual parental genotypes derived from sibling and half sibling pairs. PLoS genetics 16 (10) (2020)
Zhi Li, Jia Huang, Karen S Y Hung, Yi Deng, Yi Wang, Ya Wang, Simon S Y Lui, Henry Ka Fung Mak, Pak-Chung Sham, Eric F C Cheung, Dost Öngür, Paola Dazzan, Raymond C K Chan
Cerebellar hypoactivation is associated with impaired sensory integration in schizophrenia. Journal of abnormal psychology 130 (1) (2020)
Justin D Tubbs, Yan Dora Zhang, Pak-Chung Sham
Intermediate confounding in trio relationships: The importance of complete data in effect size estimation. Genetic epidemiology 44 (4) (2020)
Timothy Shin-Heng Mak, Yee-Ki Lee, Clara Sze Man Tang, JoJo S H Hai, Xinru Ran, Pak-Chung Sham, Hung-Fat Tse
Coverage and diagnostic yield of Whole Exome Sequencing for the Evaluation of Cases with Dilated and Hypertrophic Cardiomyopathy. Scientific reports 8 (1) (2018)