Pamela J Lein

Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 42

Top Venues

ACS chemical neuroscience

Toxics

Archives of toxicology

Environmental science & technology

University of California Davis School of Veterinary Medicine

University at Buffalo - The State University of New York (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of California Davis School of Veterinary Medicine

United States

Professor of Neurotoxicology :: Molecular Biosciences

University of California Davis School of Veterinary Medicine

United States

Associate Professor :: Molecular Biosciences

Oregon Health and Science University

United States

Scientist (Associate Professor equivalent) :: Center for Research on Occupational and Environmental Toxicology

Johns Hopkins University Bloomberg School of Public Health

United States

Assistant Professor :: Environmental Health Sciences, Division of Toxicological Sciences

Canisius College

United States

Assistant Professor :: Biology

Dames and Moore

United States

Environmental Health Analyst :: West Valley Demonstration Project

Buffalo General Medical Center

United States

Research Associate :: Medicine/Division of Gastroenterology

Cornell University College of Veterinary Medicine

United States

Laboratory Technician :: Physiology

Education History

University at Buffalo - The State University of New York

United States

PHD :: Pharmacology and Toxicology

East Tennessee State University

United States

MSC :: Environmental Health Sciences

Cornell University

United States

BSC

Publications

Peter M Andrew, Wayne Wei Feng, Jonas J Calsbeek, Shane P Antrobus, Gennady A Cherednychenko, Jeremy A MacMahon, Pedro N Bernardino, Xiuzhen Liu, Danielle J Harvey, Pamela J Lein, Isaac N Pessah
The α4 Nicotinic Acetylcholine Receptor Is Necessary for the Initiation of Organophosphate-Induced Neuronal Hyperexcitability. Toxics 12 (4) (2024)
Peter M Andrew, Wayne Wei Feng, Jonas J Calsbeek, Shane P Antrobus, Gennady A Cherednychenko, Jeremy A MacMahon, Pedro N Bernardino, Xiuzhen Liu, Danielle J Harvey, Pamela J Lein, Isaac N Pessah
The α4 Nicotinic Acetylcholine Receptor Is Necessary for the Initiation of Organophosphate-Induced Neuronal Hyperexcitability. Toxics 12 (4) (2024)
Peter M Andrew, Wayne Wei Feng, Jonas J Calsbeek, Shane P Antrobus, Gennady A Cherednychenko, Jeremy A MacMahon, Pedro N Bernardino, Xiuzhen Liu, Danielle J Harvey, Pamela J Lein, Isaac N Pessah
The α4 Nicotinic Acetylcholine Receptor Is Necessary for the Initiation of Organophosphate-Induced Neuronal Hyperexcitability. Toxics 12 (4) (2024)
Peter M Andrew, Wayne Wei Feng, Jonas J Calsbeek, Shane P Antrobus, Gennady A Cherednychenko, Jeremy A MacMahon, Pedro N Bernardino, Xiuzhen Liu, Danielle J Harvey, Pamela J Lein, Isaac N Pessah
The α4 Nicotinic Acetylcholine Receptor Is Necessary for the Initiation of Organophosphate-Induced Neuronal Hyperexcitability. Toxics 12 (4) (2024)
Robert J Tombari, Paige C Mundy, Kelly M Morales, Lee E Dunlap, David E Olson, Pamela J Lein
Developmental Neurotoxicity Screen of Psychedelics and Other Drugs of Abuse in Larval Zebrafish ( Danio rerio ). ACS chemical neuroscience 14 (5) (2023)
Pedro N Bernardino, Audrey S Luo, Peter M Andrew, Chelsea M Unkel, Marco I Gonzalez, Angie Gelli, Pamela J Lein
Evidence implicating blood-brain barrier impairment in the pathogenesis of acquired epilepsy following acute organophosphate intoxication . The Journal of pharmacology and experimental therapeutics (2023)
Chun-Yun Zhang, Xueshu Li, Kimberly P Keil Stietz, Sunjay Sethi, Weizhu Yang, Rachel F Marek, Xinxin Ding, Pamela J Lein, Keri C Hornbuckle, Hans-Joachim Lehmler
Rebuttal to Correspondence on "Machine Learning-Assisted Identification and Quantification of Hydroxylated Metabolites of Polychlorinated Biphenyls in Animal Samples". Environmental science & technology (2023)
Simone Sandoval, Keegan Malany, Krista Thongphanh, Clarisa A Martinez, Michael L Goodson, Felipe Da Costa Souza, Lo-Wei Lin, Jamie Pennington, Pamela J Lein, Nancy I Kerkvliet, Allison K Ehrlich
Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2 responding CD4 + T cells. bioRxiv : the preprint server for biology (2023)
Robert J Tombari, Paige C Mundy, Kelly M Morales, Lee E Dunlap, David E Olson, Pamela J Lein
Developmental Neurotoxicity Screen of Psychedelics and Other Drugs of Abuse in Larval Zebrafish ( Danio rerio ). ACS chemical neuroscience (2023)
Robert J Tombari, Paige C Mundy, Kelly M Morales, Lee E Dunlap, David E Olson, Pamela J Lein
Developmental Neurotoxicity Screen of Psychedelics and Other Drugs of Abuse in Larval Zebrafish ( Danio rerio ). ACS chemical neuroscience 14 (5) (2023)
Paige C Mundy, Alicia Werner, Latika Singh, Vikrant Singh, Rosalia Mendieta, Caitlyn E Patullo, Heike Wulff, Pamela J Lein
Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) causes seizure activity in larval zebrafish via antagonism of γ-aminobutyric acid type A receptor α1β2γ2. Archives of toxicology (2023)
Robert J Tombari, Paige C Mundy, Kelly M Morales, Lee E Dunlap, David E Olson, Pamela J Lein
Developmental Neurotoxicity Screen of Psychedelics and Other Drugs of Abuse in Larval Zebrafish ( Danio rerio ). ACS chemical neuroscience 14 (5) (2023)
Robert J Tombari, Paige C Mundy, Kelly M Morales, Lee E Dunlap, David E Olson, Pamela J Lein
Developmental Neurotoxicity Screen of Psychedelics and Other Drugs of Abuse in Larval Zebrafish ( Danio rerio ). ACS chemical neuroscience 14 (5) (2023)
Robert J Tombari, Paige C Mundy, Kelly M Morales, Lee E Dunlap, David E Olson, Pamela J Lein
Developmental Neurotoxicity Screen of Psychedelics and Other Drugs of Abuse in Larval Zebrafish ( Danio rerio ). ACS chemical neuroscience 14 (5) (2023)
Robert J Tombari, Paige C Mundy, Kelly M Morales, Lee E Dunlap, David E Olson, Pamela J Lein
Developmental Neurotoxicity Screen of Psychedelics and Other Drugs of Abuse in Larval Zebrafish ( Danio rerio ). ACS chemical neuroscience (2023)
Robert J Tombari, Paige C Mundy, Kelly M Morales, Lee E Dunlap, David E Olson, Pamela J Lein
Developmental Neurotoxicity Screen of Psychedelics and Other Drugs of Abuse in Larval Zebrafish ( Danio rerio ). ACS chemical neuroscience 14 (5) (2023)
Robert J Tombari, Paige C Mundy, Kelly M Morales, Lee E Dunlap, David E Olson, Pamela J Lein
Developmental Neurotoxicity Screen of Psychedelics and Other Drugs of Abuse in Larval Zebrafish ( Danio rerio ). ACS chemical neuroscience 14 (5) (2023)
Paige C Mundy, Alicia Werner, Latika Singh, Vikrant Singh, Rosalia Mendieta, Caitlyn E Patullo, Heike Wulff, Pamela J Lein
Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) causes seizure activity in larval zebrafish via antagonism of γ-aminobutyric acid type A receptor α1β2γ2. Archives of toxicology (2023)
Chun-Yun Zhang, Xueshu Li, Kimberly P Keil Stietz, Sunjay Sethi, Weizhu Yang, Rachel F Marek, Xinxin Ding, Pamela J Lein, Keri C Hornbuckle, Hans-Joachim Lehmler
Machine Learning-Assisted Identification and Quantification of Hydroxylated Metabolites of Polychlorinated Biphenyls in Animal Samples. Environmental science & technology 56 (18) (2022)
Keith J Bein, Chris D Wallis, Jill L Silverman, Pamela J Lein, Anthony S Wexler
Emulating Near-Roadway Exposure to Traffic-Related Air Pollution via Real-Time Emissions from a Major Freeway Tunnel System. Environmental science & technology (2022)
Hao Chen, Rhianna K Carty, Adrienne C Bautista, Keri A Hayakawa, Pamela J Lein
Triiodothyronine or Antioxidants Block the Inhibitory Effects of BDE-47 and BDE-49 on Axonal Growth in Rat Hippocampal Neuron-Glia Co-Cultures. Toxics 10 (2) (2022)
Chun-Yun Zhang, Carolyn R Klocke, Pamela J Lein, Hans-Joachim Lehmler
Disposition of PCB 11 in Mice Following Acute Oral Exposure. Chemical research in toxicology 34 (4) (2021)
Lauren Matelski, Rhianna K Morgan, Ana Cristina Grodzki, Judy Van de Water, Pamela J Lein
Effects of cytokines on nuclear factor-kappa B, cell viability, and synaptic connectivity in a human neuronal cell line. Molecular psychiatry 26 (3) (2020)
Elizabeth L Berg, Lauren R Pedersen, Michael C Pride, Stela P Petkova, Kelley T Patten, Anthony E Valenzuela, Christopher Wallis, Keith J Bein, Anthony S Wexler, Pamela J Lein, Jill L Silverman
Developmental exposure to near roadway pollution produces behavioral phenotypes relevant to neurodevelopmental disorders in juvenile rats. Translational psychiatry 10 (1) (2020)
Kelley T Patten, Eduardo A González, Anthony Valenzuela, Elizabeth L Berg, Christopher Wallis, Joel R Garbow, Jill L Silverman, Keith J Bein, Anthony S Wexler, Pamela J Lein
Effects of early life exposure to traffic-related air pollution on brain development in juvenile Sprague-Dawley rats. Translational psychiatry 10 (1) (2020)
Ashish Dhir, Donald A Bruun, Michelle Guignet, Yi-Hua Tsai, Eduardo González, Jonas Calsbeek, Joan Vu, Naomi Saito, Daniel J Tancredi, Danielle J Harvey, Pamela J Lein, Michael A Rogawski
Allopregnanolone and perampanel as adjuncts to midazolam for treating diisopropylfluorophosphate-induced status epilepticus in rats. Annals of the New York Academy of Sciences 1480 (1) (2020)
Tamara Tal, Bianca Yaghoobi, Pamela J Lein
Translational Toxicology in Zebrafish. Current opinion in toxicology (2020)
Eduardo A González, Alexa C Rindy, Michelle A Guignet, Jonas J Calsbeek, Donald A Bruun, Ashish Dhir, Peter Andrew, Naomi Saito, Douglas J Rowland, Danielle J Harvey, Michael A Rogawski, Pamela J Lein
The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity. Archives of toxicology 94 (6) (2020)
Harmanpreet Kaur Panesar, Conner L Kennedy, Kimberly P Keil Stietz, Pamela J Lein
Polychlorinated Biphenyls (PCBs): Risk Factors for Autism Spectrum Disorder? Toxics 8 (3) (2020)
Lee E Dunlap, Arya Azinfar, Calvin Ly, Lindsay P Cameron, Jayashri Viswanathan, Robert J Tombari, Douglas Myers-Turnbull, Jack C Taylor, Ana Cristina Grodzki, Pamela J Lein, David Kokel, David E Olson
Identification of Psychoplastogenic N,N-Dimethylaminoisotryptamine (isoDMT) Analogues through Structure-Activity Relationship Studies. Journal of medicinal chemistry 63 (3) (2020)
Lindsay P Cameron, Robert J Tombari, Ju Lu, Alexander J Pell, Zefan Q Hurley, Yann Ehinger, Maxemiliano V Vargas, Matthew N McCarroll, Jack Carson Taylor, Douglas Myers-Turnbull, Taohui Liu, Bianca Yaghoobi, Lauren J Laskowski, Emilie I Anderson, Guoliang Zhang, Jayashri Viswanathan, Brandon M Brown, Michelle Tjia, Lee E Dunlap, Zachary T Rabow, Oliver Fiehn, Heike Wulff, John D McCorvy, Pamela J Lein, David Kokel, Dorit Ron, Jamie Peters, Yi Zuo, David E Olson
A non-hallucinogenic psychedelic analogue with therapeutic potential. Nature 589 (7842) (2020)
Becky J Proskocil, Ana Cristina G Grodzki, David B Jacoby, Pamela J Lein, Allison D Fryer
Organophosphorus Pesticides Induce Cytokine Release from Differentiated Human THP1 Cells. American journal of respiratory cell and molecular biology 61 (5) (2020)
Carolyn Klocke, Sunjay Sethi, Pamela J Lein
The developmental neurotoxicity of legacy vs. contemporary polychlorinated biphenyls (PCBs): similarities and differences. Environmental science and pollution research international 27 (9) (2019)
Sunjay Sethi, Rhianna K Morgan, Wei Feng, Yanping Lin, Xueshu Li, Corey Luna, Madison Koch, Ruby Bansal, Michael W Duffel, Birgit Puschner, R Thomas Zoeller, Hans-Joachim Lehmler, Isaac N Pessah, Pamela J Lein
Comparative Analyses of the 12 Most Abundant PCB Congeners Detected in Human Maternal Serum for Activity at the Thyroid Hormone Receptor and Ryanodine Receptor. Environmental science & technology 53 (7) (2019)
Isaac N Pessah, Pamela J Lein, Richard F Seegal, Sharon K Sagiv
Neurotoxicity of polychlorinated biphenyls and related organohalogens. Acta neuropathologica 138 (3) (2019)
Sunjay Sethi, Kimberly P Keil, Pamela J Lein
3,3'-Dichlorobiphenyl (PCB 11) promotes dendritic arborization in primary rat cortical neurons via a CREB-dependent mechanism. Archives of toxicology 92 (11) (2018)
Frances C Shaffo, Ana Cristina Grodzki, Allison D Fryer, Pamela J Lein
Mechanisms of organophosphorus pesticide toxicity in the context of airway hyperreactivity and asthma. American journal of physiology. Lung cellular and molecular physiology 315 (4) (2018)
Alexander E Hampe, Zidong Li, Sunjay Sethi, Pamela J Lein, Erkin Seker
A Microfluidic Platform to Study Astrocyte Adhesion on Nanoporous Gold Thin Films. Nanomaterials (Basel, Switzerland) 8 (7) (2018)
Kimberly P Keil, Galen W Miller, Hao Chen, Sunjay Sethi, Martin R Schmuck, Kiran Dhakal, Ji Won Kim, Pamela J Lein
PCB 95 promotes dendritic growth in primary rat hippocampal neurons via mTOR-dependent mechanisms. Archives of toxicology 92 (10) (2018)
Sunjay Sethi, Kimberly P Keil, Pamela J Lein
Species and Sex Differences in the Morphogenic Response of Primary Rodent Neurons to 3,3'-Dichlorobiphenyl (PCB 11). Toxics 6 (1) (2017)
Becky J Proskocil, Donald A Bruun, Jasmine A Garg, Chloe C Villagomez, David B Jacoby, Pamela J Lein, Allison D Fryer
The influence of sensitization on mechanisms of organophosphorus pesticide-induced airway hyperreactivity. American journal of respiratory cell and molecular biology 53 (5) (2016)
Brenna M Flannery, Donald A Bruun, Douglas J Rowland, Christopher N Banks, Adam T Austin, David L Kukis, Yonggang Li, Byron D Ford, Daniel J Tancredi, Jill L Silverman, Simon R Cherry, Pamela J Lein
Persistent neuroinflammation and cognitive impairment in a rat model of acute diisopropylfluorophosphate intoxication. Journal of neuroinflammation 13 (1) (2016)
Ana Cristina G Grodzki, Bhaskar Poola, Nagarekha Pasupuleti, Michael H Nantz, Pamela J Lein, Fredric Gorin
A novel carboline derivative inhibits nitric oxide formation in macrophages independent of effects on tumor necrosis factor α and interleukin-1β expression. The Journal of pharmacology and experimental therapeutics 352 (3) (2014)

Pamela J Lein.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Pamela J Lein