Qi-Hua Zhu (Qihua Zhu)

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 19

Top Topics

Breast Cancer Cells

Structure Activity Relationship

Top Venues

Journal of medicinal chemistry

Cell death & disease

This page only lists publications with an associated author ORCID identifier.

Publications

Yongling Xu, Huijie Du, Weibo Guo, Beibei Liu, Wenxin Yan, Chi Zhang, Long Qin, Jingling Huang, Hongxia Wang, Shiqi Wu, Weijie Ren, Yi Zou, Jie Wang, Qi-Hua Zhu, Yun-Gen Xu, Hongfeng Gu
Discovery of Highly Potent Small-Molecule PD-1/PD-L1 Inhibitors with a Novel Scaffold for Cancer Immunotherapy. Journal of medicinal chemistry 67 (5) (2024)
Yongling Xu, Huijie Du, Weibo Guo, Beibei Liu, Wenxin Yan, Chi Zhang, Long Qin, Jingling Huang, Hongxia Wang, Shiqi Wu, Weijie Ren, Yi Zou, Jie Wang, Qi-Hua Zhu, Yun-Gen Xu, Hongfeng Gu
Discovery of Highly Potent Small-Molecule PD-1/PD-L1 Inhibitors with a Novel Scaffold for Cancer Immunotherapy. Journal of medicinal chemistry (2024)
Zeren Sun, Lanjie Li, Bingxin Zhai, Mengxuan Hu, Lei Huang, Shihui Huang, Liu Ye, Xiangying Kong, Jie Xu, Jie Bai, Jingjie Yan, Qichen Zhou, Zheqi Hu, Yuchen Zhang, Yuhan Jiang, Yan Zhang, Zhou Qiao, Yi Zou, Yun-Gen Xu, Qi-Hua Zhu
Rational Design of PARP1/c-Met Dual Inhibitors for Overcoming PARP1 Inhibitor Resistance Induced by c-Met Overexpression. Journal of medicinal chemistry (2024)
Zeren Sun, Lanjie Li, Bingxin Zhai, Mengxuan Hu, Lei Huang, Shihui Huang, Liu Ye, Xiangying Kong, Jie Xu, Jie Bai, Jingjie Yan, Qichen Zhou, Zheqi Hu, Yuchen Zhang, Yuhan Jiang, Yan Zhang, Zhou Qiao, Yi Zou, Yun-Gen Xu, Qi-Hua Zhu
Rational Design of PARP1/c-Met Dual Inhibitors for Overcoming PARP1 Inhibitor Resistance Induced by c-Met Overexpression. Journal of medicinal chemistry 67 (6) (2024)
Gaofeng Lin, Qinlong Xu, Jiaming Li, Zhaoxing Chu, Xiaodong Ma, Qi-Hua Zhu, Yan Zhao, Jiajia Mo, Wenfeng Ye, Li Shao, Tao Fang, Minghan He, Shaoyun Yue, Mingqi Dai
Design, Synthesis, and Biological Evaluation of Pierardine Derivatives as Novel Brain-Penetrant and In Vivo Potent NMDAR-GluN2B Antagonists for Ischemic Stroke Treatment. Journal of medicinal chemistry (2024)
Zeren Sun, Lanjie Li, Bingxin Zhai, Mengxuan Hu, Lei Huang, Shihui Huang, Liu Ye, Xiangying Kong, Jie Xu, Jie Bai, Jingjie Yan, Qichen Zhou, Zheqi Hu, Yuchen Zhang, Yuhan Jiang, Yan Zhang, Zhou Qiao, Yi Zou, Yun-Gen Xu, Qi-Hua Zhu
Rational Design of PARP1/c-Met Dual Inhibitors for Overcoming PARP1 Inhibitor Resistance Induced by c-Met Overexpression. Journal of medicinal chemistry 67 (6) (2024)
Gaofeng Lin, Qinlong Xu, Jiaming Li, Zhaoxing Chu, Xiaodong Ma, Qi-Hua Zhu, Yan Zhao, Jiajia Mo, Wenfeng Ye, Li Shao, Tao Fang, Minghan He, Shaoyun Yue, Mingqi Dai
Design, Synthesis, and Biological Evaluation of Pierardine Derivatives as Novel Brain-Penetrant and In Vivo Potent NMDAR-GluN2B Antagonists for Ischemic Stroke Treatment. Journal of medicinal chemistry 67 (5) (2024)
Yongling Xu, Huijie Du, Weibo Guo, Beibei Liu, Wenxin Yan, Chi Zhang, Long Qin, Jingling Huang, Hongxia Wang, Shiqi Wu, Weijie Ren, Yi Zou, Jie Wang, Qi-Hua Zhu, Yun-Gen Xu, Hongfeng Gu
Discovery of Highly Potent Small-Molecule PD-1/PD-L1 Inhibitors with a Novel Scaffold for Cancer Immunotherapy. Journal of medicinal chemistry 67 (5) (2024)
Gaofeng Lin, Qinlong Xu, Jiaming Li, Zhaoxing Chu, Xiaodong Ma, Qi-Hua Zhu, Yan Zhao, Jiajia Mo, Wenfeng Ye, Li Shao, Tao Fang, Minghan He, Shaoyun Yue, Mingqi Dai
Design, Synthesis, and Biological Evaluation of Pierardine Derivatives as Novel Brain-Penetrant and In Vivo Potent NMDAR-GluN2B Antagonists for Ischemic Stroke Treatment. Journal of medicinal chemistry 67 (5) (2024)
Hongfeng Gu, Wenxin Yan, Jieping Yang, Beibei Liu, Xiaolin Zhao, Hongxia Wang, Wenbo Xu, Chenghao Wang, Yang Chen, Qiuyi Dong, Qi-Hua Zhu, Yun-Gen Xu, Yi Zou
Discovery of Highly Selective PARP7 Inhibitors with a Novel Scaffold for Cancer Immunotherapy. Journal of medicinal chemistry (2023)
Hongfeng Gu, Wenxin Yan, Yong Wang, Wenbo Xu, Lei Huang, Jieping Yang, Bingxin Zhai, Hong Wang, Yupei Su, Qi-Hua Zhu, Beibei Liu, Haiping Hao, Yi Zou, Yun-Gen Xu
Discovery of the Potent and Highly Selective PARP7 Inhibitor as a Novel Immunotherapeutic Agent for Tumors. Journal of medicinal chemistry (2022)
Guangchao He, Sheng Wan, Yunze Wu, Zhaoxing Chu, Hui Shen, Shan Zhang, Linya Chen, Zijing Bao, Shuhui Gu, Junzhang Huang, Lei Huang, Guoqing Gong, Yi Zou, Qi-Hua Zhu, Yun-Gen Xu
Discovery of the First Selective IDO2 Inhibitor As Novel Immunotherapeutic Avenues for Rheumatoid Arthritis. Journal of medicinal chemistry 65 (21) (2022)
Shi Shi, Yu Du, Yi Zou, Jing Niu, Zeyu Cai, Xiaonan Wang, Feihuang Qiu, Yi Ding, Gengchen Yang, Yunze Wu, Yun-Gen Xu, Qi-Hua Zhu
Rational Design for Nitroreductase (NTR)-Responsive Proteolysis Targeting Chimeras (PROTACs) Selectively Targeting Tumor Tissues. Journal of medicinal chemistry 65 (6) (2022)
Hongfeng Gu, Wenxin Yan, Yong Wang, Wenbo Xu, Lei Huang, Jieping Yang, Bingxin Zhai, Hong Wang, Yupei Su, Qi-Hua Zhu, Beibei Liu, Haiping Hao, Yi Zou, Yun-Gen Xu
Discovery of the Potent and Highly Selective PARP7 Inhibitor as a Novel Immunotherapeutic Agent for Tumors. Journal of medicinal chemistry 66 (1) (2022)
Hongfeng Gu, Wenxin Yan, Yong Wang, Wenbo Xu, Lei Huang, Jieping Yang, Bingxin Zhai, Hong Wang, Yupei Su, Qi-Hua Zhu, Beibei Liu, Haiping Hao, Yi Zou, Yun-Gen Xu
Discovery of the Potent and Highly Selective PARP7 Inhibitor as a Novel Immunotherapeutic Agent for Tumors. Journal of medicinal chemistry 66 (1) (2022)
Hongfeng Gu, Wenxin Yan, Yong Wang, Wenbo Xu, Lei Huang, Jieping Yang, Bingxin Zhai, Hong Wang, Yupei Su, Qi-Hua Zhu, Beibei Liu, Haiping Hao, Yi Zou, Yun-Gen Xu
Discovery of the Potent and Highly Selective PARP7 Inhibitor as a Novel Immunotherapeutic Agent for Tumors. Journal of medicinal chemistry 66 (1) (2022)
Shu-Ping Wang, Shi-Qi Wu, Shi-Hui Huang, Yi-Xuan Tang, Liu-Qiong Meng, Feng Liu, Qi-Hua Zhu, Yun-Gen Xu
FDI-6 inhibits the expression and function of FOXM1 to sensitize BRCA-proficient triple-negative breast cancer cells to Olaparib by regulating cell cycle progression and DNA damage repair. Cell death & disease 12 (12) (2021)
Xin He, Guangchao He, Zhaoxing Chu, Huanhuan Wu, Junjie Wang, Yiran Ge, Hui Shen, Shan Zhang, Jinxi Shan, Kewen Peng, Zhifeng Wei, Yi Zou, Yun-Gen Xu, Qi-Hua Zhu
Discovery of the First Potent IDO1/IDO2 Dual Inhibitors: A Promising Strategy for Cancer Immunotherapy. Journal of medicinal chemistry (2021)
Shu-Ping Wang, Yu Li, Shi-Hui Huang, Shi-Qi Wu, Ling-Li Gao, Qin Sun, Qian-Wen Lin, Lei Huang, Liu-Qiong Meng, Yi Zou, Qi-Hua Zhu, Yun-Gen Xu
Discovery of Potent and Novel Dual PARP/BRD4 Inhibitors for Efficient Treatment of Pancreatic Cancer. Journal of medicinal chemistry 64 (23) (2021)