Raffael Schaffrath

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 37

Top Topics

Saccharomyces Cerevisiae

Quality Control

Top Venues

Nucleic acids research

Nature communications

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Katharina Görlitz, Larissa Bessler, Mark Helm, Raffael Schaffrath, Roland Klassen
Fluoropyrimidines trigger decay of hypomodified tRNA in yeast. Nucleic acids research 52 (10) (2024)
Nour El Hana Abbassi, Marcin Jaciuk, David Scherf, Pauline Böhnert, Alexander Rau, Alexander Hammermeister, Michal Rawski, Paulina Indyka, Grzegorz Wazny, Andrzej Chramiec-Głąbik, Dominika Dobosz, Bozena Skupien-Rabian, Urszula Jankowska, Juri Rappsilber, Raffael Schaffrath, Ting-Yu Lin, Sebastian Glatt
Cryo-EM structures of the human Elongator complex at work. Nature communications 15 (1) (2024)
Nour El Hana Abbassi, Marcin Jaciuk, David Scherf, Pauline Böhnert, Alexander Rau, Alexander Hammermeister, Michal Rawski, Paulina Indyka, Grzegorz Wazny, Andrzej Chramiec-Głąbik, Dominika Dobosz, Bozena Skupien-Rabian, Urszula Jankowska, Juri Rappsilber, Raffael Schaffrath, Ting-Yu Lin, Sebastian Glatt
Cryo-EM structures of the human Elongator complex at work. Nature communications 15 (1) (2024)
Sang Eun Jun, Kiu-Hyung Cho, Raffael Schaffrath, Gyung-Tae Kim
Evolutionary Conservation in Protein-Protein Interactions and Structures of the Elongator Sub-Complex ELP456 from Arabidopsis and Yeast. International journal of molecular sciences 25 (8) (2024)
Koray Ütkür, Klaus Mayer, Shihui Liu, Ulrich Brinkmann, Raffael Schaffrath
Functional Integrity of Radical SAM Enzyme Dph1•Dph2 Requires Non-Canonical Cofactor Motifs with Tandem Cysteines. Biomolecules 14 (4) (2024)
Koray Ütkür, Klaus Mayer, Shihui Liu, Ulrich Brinkmann, Raffael Schaffrath
Functional Integrity of Radical SAM Enzyme Dph1•Dph2 Requires Non-Canonical Cofactor Motifs with Tandem Cysteines. Biomolecules 14 (4) (2024)
Sang Eun Jun, Kiu-Hyung Cho, Raffael Schaffrath, Gyung-Tae Kim
Evolutionary Conservation in Protein-Protein Interactions and Structures of the Elongator Sub-Complex ELP456 from Arabidopsis and Yeast. International journal of molecular sciences 25 (8) (2024)
Nour El Hana Abbassi, Marcin Jaciuk, David Scherf, Pauline Böhnert, Alexander Rau, Alexander Hammermeister, Michal Rawski, Paulina Indyka, Grzegorz Wazny, Andrzej Chramiec-Głąbik, Dominika Dobosz, Bozena Skupien-Rabian, Urszula Jankowska, Juri Rappsilber, Raffael Schaffrath, Ting-Yu Lin, Sebastian Glatt
Cryo-EM structures of the human Elongator complex at work. Nature communications 15 (1) (2024)
Koray Ütkür, Klaus Mayer, Shihui Liu, Ulrich Brinkmann, Raffael Schaffrath
Functional Integrity of Radical SAM Enzyme Dph1•Dph2 Requires Non-Canonical Cofactor Motifs with Tandem Cysteines. Biomolecules 14 (4) (2024)
Katharina Görlitz, Larissa Bessler, Mark Helm, Raffael Schaffrath, Roland Klassen
Fluoropyrimidines trigger decay of hypomodified tRNA in yeast. Nucleic acids research 52 (10) (2024)
Nour El Hana Abbassi, Marcin Jaciuk, David Scherf, Pauline Böhnert, Alexander Rau, Alexander Hammermeister, Michal Rawski, Paulina Indyka, Grzegorz Wazny, Andrzej Chramiec-Głąbik, Dominika Dobosz, Bozena Skupien-Rabian, Urszula Jankowska, Juri Rappsilber, Raffael Schaffrath, Ting-Yu Lin, Sebastian Glatt
Cryo-EM structures of the human Elongator complex at work. Nature communications 15 (1) (2024)
Katharina Görlitz, Larissa Bessler, Mark Helm, Raffael Schaffrath, Roland Klassen
Fluoropyrimidines trigger decay of hypomodified tRNA in yeast. Nucleic acids research (2024)
Sang Eun Jun, Kiu-Hyung Cho, Raffael Schaffrath, Gyung-Tae Kim
Evolutionary Conservation in Protein-Protein Interactions and Structures of the Elongator Sub-Complex ELP456 from Arabidopsis and Yeast. International journal of molecular sciences 25 (8) (2024)
Koray Ütkür, Sarina Schmidt, Klaus Mayer, Roland Klassen, Ulrich Brinkmann, Raffael Schaffrath
DPH1 Gene Mutations Identify a Candidate SAM Pocket in Radical Enzyme Dph1•Dph2 for Diphthamide Synthesis on EF2. Biomolecules 13 (11) (2023)
Mark Helm, Markus T Bohnsack, Thomas Carell, Alexander Dalpke, Karl-Dieter Entian, Ann Ehrenhofer-Murray, Alaa Shaikhqasem, Christian Hammann, Claudia Höbartner, Andres Jäschke, Albert Jeltsch, Stefanie M Kellner, Roland Klassen, Sebastian A Leidel, Andreas Marx, Mario Mörl, Jochen C Meier, Gunter Meister, Andrea Rentmeister, Marina Rodnina, Jean-Yves Roignant, Raffael Schaffrath, Peter Stadler, Thorsten Stafforst
Experience with German Research Consortia in the Field of Chemical Biology of Native Nucleic Acid Modifications. ACS chemical biology (2023)
Koray Ütkür, Klaus Mayer, Maliha Khan, Thirishika Manivannan, Raffael Schaffrath, Ulrich Brinkmann
Alleles that confer susceptibility to diphthamide deficiency syndrome: analyses of DPH1 & DPH2 variants in human cells and yeast. Disease models & mechanisms (2023)
Marcin Jaciuk, David Scherf, Karol Kaszuba, Monika Gaik, Alexander Rau, Anna Kościelniak, Rościsław Krutyhołowa, Michał Rawski, Paulina Indyka, Andrea Graziadei, Andrzej Chramiec-Głąbik, Anna Biela, Dominika Dobosz, Ting-Yu Lin, Nour-El-Hana Abbassi, Alexander Hammermeister, Juri Rappsilber, Jan Kosinski, Raffael Schaffrath, Sebastian Glatt
Cryo-EM structure of the fully assembled Elongator complex. Nucleic acids research 51 (5) (2023)
Marcin Jaciuk, David Scherf, Karol Kaszuba, Monika Gaik, Alexander Rau, Anna Kościelniak, Rościsław Krutyhołowa, Michał Rawski, Paulina Indyka, Andrea Graziadei, Andrzej Chramiec-Głąbik, Anna Biela, Dominika Dobosz, Ting-Yu Lin, Nour-El-Hana Abbassi, Alexander Hammermeister, Juri Rappsilber, Jan Kosinski, Raffael Schaffrath, Sebastian Glatt
Cryo-EM structure of the fully assembled Elongator complex. Nucleic acids research (2023)
Marcin Jaciuk, David Scherf, Karol Kaszuba, Monika Gaik, Alexander Rau, Anna Kościelniak, Rościsław Krutyhołowa, Michał Rawski, Paulina Indyka, Andrea Graziadei, Andrzej Chramiec-Głąbik, Anna Biela, Dominika Dobosz, Ting-Yu Lin, Nour-El-Hana Abbassi, Alexander Hammermeister, Juri Rappsilber, Jan Kosinski, Raffael Schaffrath, Sebastian Glatt
Cryo-EM structure of the fully assembled Elongator complex. Nucleic acids research 51 (5) (2023)
Marcin Jaciuk, David Scherf, Karol Kaszuba, Monika Gaik, Alexander Rau, Anna Kościelniak, Rościsław Krutyhołowa, Michał Rawski, Paulina Indyka, Andrea Graziadei, Andrzej Chramiec-Głąbik, Anna Biela, Dominika Dobosz, Ting-Yu Lin, Nour-El-Hana Abbassi, Alexander Hammermeister, Juri Rappsilber, Jan Kosinski, Raffael Schaffrath, Sebastian Glatt
Cryo-EM structure of the fully assembled Elongator complex. Nucleic acids research 51 (5) (2023)
Gabriel Soares Matos, Leonie Vogt, Rosangela Silva Santos, Aurélien Devillars, Marcos Yukio Yoshinaga, Sayuri Miyamoto, Raffael Schaffrath, Monica Montero-Lomeli, Roland Klassen
Lipidome remodeling in response to nutrient replenishment requires the tRNA modifier Deg1/Pus3 in yeast. Molecular microbiology (2023)
Hongliang Zhang, Julia Quintana, Koray Ütkür, Lorenz Adrian, Harmen Hawer, Klaus Mayer, Xiaodi Gong, Leonardo Castanedo, Anna Schulten, Nadežda Janina, Marcus Peters, Ruediger Hell, Ulrich Brinkmann, Raffael Schaffrath, Ute Krämer
Translational fidelity and growth of Arabidopsis require stress-sensitive diphthamide biosynthesis. Nature communications 13 (1) (2022)
Keerthiraju Ethiraju Ravichandran, Lars Kaduhr, Bozena Skupien-Rabian, Ekaterina Shvetsova, Mikołaj Sokołowski, Ros Cisław Krutyhołowa, Dominika Kwasna, Cindy Brachmann, Sean Lin, Sebastian Guzman Perez, Piotr Wilk, Manuel Kösters, Przemysław Grudnik, Urszula Jankowska, Sebastian Andreas Leidel, Raffael Schaffrath, Sebastian Glatt
E2/E3-independent ubiquitin-like protein conjugation by Urm1 is directly coupled to cysteine persulfidation. The EMBO journal 41 (20) (2022)
Benjamin J Freije, Wilson M Freije, To Uyen Do, Grace E Adkins, Alexander Bruch, Jennifer E Hurtig, Kevin A Morano, Raffael Schaffrath, James D West
Identifying Interaction Partners of Yeast Protein Disulfide Isomerases Using a Small Thiol-Reactive Cross-Linker: Implications for Secretory Pathway Proteostasis. Chemical research in toxicology 35 (2) (2022)
Bahar Khonsari, Roland Klassen, Raffael Schaffrath
Role of SSD1 in Phenotypic Variation of Saccharomyces cerevisiae Strains Lacking DEG1-Dependent Pseudouridylation. International journal of molecular sciences 22 (16) (2021)
Leticia Pollo-Oliveira, Roland Klassen, Nick Davis, Akif Ciftci, Jo Marie Bacusmo, Maria Martinelli, Michael S DeMott, Thomas J Begley, Peter C Dedon, Raffael Schaffrath, Valérie de Crécy-Lagard
Loss of Elongator- and KEOPS-Dependent tRNA Modifications Leads to Severe Growth Phenotypes and Protein Aggregation in Yeast. Biomolecules 10 (2) (2020)
Roland Klassen, Alexander Bruch, Raffael Schaffrath
Induction of protein aggregation and starvation response by tRNA modification defects. Current genetics 66 (6) (2020)
Harmen Hawer, Bryce A Mendelsohn, Klaus Mayer, Ann Kung, Amit Malhotra, Sari Tuupanen, Jennifer Schleit, Ulrich Brinkmann, Raffael Schaffrath
Diphthamide-deficiency syndrome: a novel human developmental disorder and ribosomopathy. European journal of human genetics : EJHG 28 (11) (2020)
Michael F Jantsch, Alessandro Quattrone, Mary O'Connell, Mark Helm, Michaela Frye, Manuel Macias-Gonzales, Marie Ohman, Stefan Ameres, Luc Willems, Francois Fuks, Anastasis Oulas, Stepanka Vanacova, Henrik Nielsen, Cecile Bousquet-Antonelli, Yuri Motorin, Jean-Yves Roignant, Nikolaos Balatsos, Andras Dinnyes, Pavel Baranov, Vincent Kelly, Ayelet Lamm, Gideon Rechavi, Mattia Pelizzola, Janis Liepins, Irina Holodnuka Kholodnyuk, Vanessa Zammit, Duncan Ayers, Finn Drablos, John Arne Dahl, Janusz M Bujnicki, Carmen Jerónimo, Raquel Almeida, Monica Neagu, Marieta Costache, Jasna Bankovic, Bojana Banovic, Jan Kyselovic, Luis Miguel Valor, Stefan Selbert, Pinar Pir, Turan Demircan, Victoria Cowling, Matthias R Schaefer, Walter Rossmanith, Denis Lafontaine, Alexandre David, Clement Carre, Frank Lyko, Raffael Schaffrath, Schraga Schwartz, Andre Verdel, Arne Klungland, Elzbieta Purta, Gordana Timotijevic, Fernando Cardona, Alberto Davalos, Ester Ballana, Donal O Carroll, Jernej Ule, Rupert Fray
Positioning Europe for the EPITRANSCRIPTOMICS challenge. RNA biology 15 (6) (2018)
Roland Klassen, Raffael Schaffrath
Collaboration of tRNA modifications and elongation factor eEF1A in decoding and nonsense suppression. Scientific reports 8 (1) (2018)
Harmen Hawer, Alexander Hammermeister, Keerthiraju Ethiraju Ravichandran, Sebastian Glatt, Raffael Schaffrath, Roland Klassen
Roles of Elongator Dependent tRNA Modification Pathways in Neurodegeneration and Cancer. Genes 10 (1) (2018)
Harmen Hawer, Koray Ütkür, Meike Arend, Klaus Mayer, Lorenz Adrian, Ulrich Brinkmann, Raffael Schaffrath
Importance of diphthamide modified EF2 for translational accuracy and competitive cell growth in yeast. PloS one 13 (10) (2018)
Bruno Leonardo Bozaquel-Morais, Leonie Vogt, Valentina D'Angelo, Raffael Schaffrath, Roland Klassen, Mónica Montero-Lomelí
Protein Phosphatase Sit4 Affects Lipid Droplet Synthesis and Soraphen A Resistance Independent of Its Role in Regulating Elongator Dependent tRNA Modification. Biomolecules 8 (3) (2018)
Alexander Bruch, Roland Klassen, Raffael Schaffrath
Unfolded Protein Response Suppression in Yeast by Loss of tRNA Modifications. Genes 9 (11) (2018)
Raffael Schaffrath, Sebastian Andreas Leidel
Wobble uridine modifications-a reason to live, a reason to die?! RNA biology 14 (9) (2017)
Roland Klassen, Alexander Bruch, Raffael Schaffrath
Independent suppression of ribosomal +1 frameshifts by different tRNA anticodon loop modifications. RNA biology 14 (9) (2016)
Sabrina Iñigo, Astrid Nagels Durand, Andrés Ritter, Sabine Le Gall, Martin Termathe, Roland Klassen, Takayuki Tohge, Barbara De Coninck, Jelle Van Leene, Rebecca De Clercq, Bruno P A Cammue, Alisdair R Fernie, Kris Gevaert, Geert De Jaeger, Sebastian A Leidel, Raffael Schaffrath, Mieke Van Lijsebettens, Laurens Pauwels, Alain Goossens
Glutaredoxin GRXS17 Associates with the Cytosolic Iron-Sulfur Cluster Assembly Pathway. Plant physiology 172 (2) (2016)