Raphaël Frederick (Raphaël Frédérick)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 15

Top Topics

Mass Spectrometry

Structure Activity Relationship

Top Venues

Journal of medicinal chemistry

Expert opinion on therapeutic patents

Scientific reports

Acta crystallographica. Section E, Crystallographic communications

This page only lists publications with an associated author ORCID identifier.

Publications

Zachary Geeraerts, Izumi Ishigami, Ariel Lewis-Ballester, Khoa N Pham, Arina Kozlova, Caroline Mathieu, Raphaël Frederick, Syun-Ru Yeh
Structural Insights into Protein-Inhibitor Interactions in Human Tryptophan Dioxygenase. Journal of medicinal chemistry 67 (16) (2024)
Zachary Geeraerts, Izumi Ishigami, Ariel Lewis-Ballester, Khoa N Pham, Arina Kozlova, Caroline Mathieu, Raphaël Frederick, Syun-Ru Yeh
Structural Insights into Protein-Inhibitor Interactions in Human Tryptophan Dioxygenase. Journal of medicinal chemistry (2024)
Zachary Geeraerts, Izumi Ishigami, Ariel Lewis-Ballester, Khoa N Pham, Arina Kozlova, Caroline Mathieu, Raphaël Frederick, Syun-Ru Yeh
Structural Insights into Protein-Inhibitor Interactions in Human Tryptophan Dioxygenase. Journal of medicinal chemistry 67 (16) (2024)
Marie Solvay, Pauline Pfänder, Simon Klaessens, Luc Pilotte, Vincent Stroobant, Juliette Lamy, Stefan Naulaerts, Quentin Spillier, Raphaël Frederick, Etienne De Plaen, Christine Sers, Christiane A Opitz, Benoit J Van den Eynde, Jingjing Zhu
Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes. Journal for immunotherapy of cancer 11 (6) (2023)
Manon Mirgaux, Tanguy Scaillet, Arina Kozlova, Nikolay A Tumanov, Raphaël Frederick, Laurie Bodart, Johan Wouters
Structural study of bioisosteric derivatives of 5-(1 H -indol-3-yl)-benzotriazole and their ability to form chalcogen bonds. Acta crystallographica. Section E, Crystallographic communications 78 (Pt 4) (2022)
Arina Kozlova, Léopold Thabault, Maxime Liberelle, Simon Klaessens, Julien R C Prévost, Caroline Mathieu, Luc Pilotte, Vincent Stroobant, Benoît Van den Eynde, Raphaël Frederick
Rational Design of Original Fused-Cycle Selective Inhibitors of Tryptophan 2,3-Dioxygenase. Journal of medicinal chemistry 64 (15) (2021)
Luca X Zampieri, Martina Sboarina, Andrea Cacace, Debora Grasso, Léopold Thabault, Loïc Hamelin, Thibaut Vazeille, Elodie Dumon, Rodrigue Rossignol, Raphaël Frederick, Etienne Sonveaux, Florence Lefranc, Pierre Sonveaux
Olaparib Is a Mitochondrial Complex I Inhibitor That Kills Temozolomide-Resistant Human Glioblastoma Cells. International journal of molecular sciences 22 (21) (2021)
Quentin Spillier, Séverine Ravez, Simon Dochain, Didier Vertommen, Léopold Thabault, Olivier Feron, Raphaël Frederick
Unravelling the Allosteric Targeting of PHGDH at the ACT-Binding Domain with a Photoactivatable Diazirine Probe and Mass Spectrometry Experiments. Molecules (Basel, Switzerland) 26 (2) (2021)
Quentin Spillier, Raphaël Frederick
Phosphoglycerate dehydrogenase (PHGDH) inhibitors: a comprehensive review 2015-2020. Expert opinion on therapeutic patents 31 (7) (2021)
Arina Kozlova, Léopold Thabault, Maxime Liberelle, Simon Klaessens, Julien R C Prévost, Caroline Mathieu, Luc Pilotte, Vincent Stroobant, Benoît Van den Eynde, Raphaël Frederick
Correction to "Rational Design of Original Fused-Cycle Selective Inhibitors of Tryptophan 2,3-Dioxygenase". Journal of medicinal chemistry 64 (17) (2021)
Léopold Thabault, Lucie Brisson, Chiara Brustenga, Santiago A Martinez Gache, Julien R C Prévost, Arina Kozlova, Quentin Spillier, Maxime Liberelle, Zohra Benyahia, Joris Messens, Tamara Copetti, Pierre Sonveaux, Raphaël Frederick
Interrogating the Lactate Dehydrogenase Tetramerization Site Using (Stapled) Peptides. Journal of medicinal chemistry 63 (9) (2020)
Quentin Spillier, Didier Vertommen, Séverine Ravez, Romain Marteau, Quentin Thémans, Cyril Corbet, Olivier Feron, Johan Wouters, Raphaël Frederick
Anti-alcohol abuse drug disulfiram inhibits human PHGDH via disruption of its active tetrameric form through a specific cysteine oxidation. Scientific reports 9 (1) (2019)
Arina Kozlova, Raphaël Frederick
Current state on tryptophan 2,3-dioxygenase inhibitors: a patent review. Expert opinion on therapeutic patents 29 (1) (2019)
Séverine Ravez, Cyril Corbet, Quentin Spillier, Alice Dutu, Anita D Robin, Edouard Mullarky, Lewis C Cantley, Olivier Feron, Raphaël Frederick
α-Ketothioamide Derivatives: A Promising Tool to Interrogate Phosphoglycerate Dehydrogenase (PHGDH). Journal of medicinal chemistry 60 (4) (2017)
Séverine Ravez, Quentin Spillier, Romain Marteau, Olivier Feron, Raphaël Frederick
Challenges and Opportunities in the Development of Serine Synthetic Pathway Inhibitors for Cancer Therapy. Journal of medicinal chemistry 60 (4) (2016)