Robert William Sobol (Robert W Sobol, R W Sobol)

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 44

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

bioRxiv : the preprint server for biology

Environmental and molecular mutagenesis

Scientific reports

University of South Alabama Mitchell Cancer Institute

Temple University Health System (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of South Alabama Mitchell Cancer Institute Oct 01 2014

United States

Point Clear Charities Professor of Oncologic Sciences & Chief, Molecular & Metabolic Oncology Program :: Pharmacology

University of Pittsburgh Jun 01 2012 - Oct 01 2014

United States

Associate Professor :: Pharmacology & UPCI

University of Pittsburgh Jul 01 2002 - Jun 01 2012

United States

Assistant Professor :: Pharmacology & UPCI

Education History

Temple University Health System Jun 01 1987 - Aug 31 1991

United States

PHD :: Biochemistry

Allegheny College Sep 01 1978 - Jun 01 1982

United States

BSC :: Chemistry

Publications

Shan Yan, Shobhan Gaddameedhi, Robert William Sobol
Inspiring basic and applied research in genome integrity mechanisms: Dedication to Samuel H. Wilson. Environmental and molecular mutagenesis (2024)
Burcu Inanc, Qingming Fang, Joel F Andrews, Xuemei Zeng, Jennifer Clark, Jianfeng Li, Nupur B Dey, Md Ibrahim, Peter Sykora, Zhongxun Yu, Andrea Braganza, Marcel Verheij, Jos Jonkers, Nathan A Yates, Conchita Vens, Robert William Sobol
TRIP12 governs DNA Polymerase β involvement in DNA damage response and repair. bioRxiv : the preprint server for biology (2024)
Pinakin Pandya, Frank P Vendetti, Joseph El-Ghoubaira, Sudipta Pathak, Joshua J Deppas, Reyna Jones, Anthony V Columbus, Yunqi Zhang, Daniel Ivanov, Ziyu Huang, Kate M MacDonald, Shane M Harding, Raquel Buj, Katherine M Aird, Jan H Beumer, Robert William Sobol, Christopher J Bakkenist
Deoxyuridine-rich cytoplasmic DNA antagonizes STING-dependent innate immune responses and sensitizes resistant tumors to anti-PD-L1 therapy. bioRxiv : the preprint server for biology (2024)
Shan Yan, Shobhan Gaddameedhi, Robert William Sobol
Inspiring basic and applied research in genome integrity mechanisms: Dedication to Samuel H. Wilson. Environmental and molecular mutagenesis (2024)
Shan Yan, Shobhan Gaddameedhi, Robert William Sobol
Inspiring basic and applied research in genome integrity mechanisms: Dedication to Samuel H. Wilson. Environmental and molecular mutagenesis (2024)
Pinakin Pandya, Frank P Vendetti, Joseph El-Ghoubaira, Sudipta Pathak, Joshua J Deppas, Reyna Jones, Anthony V Columbus, Yunqi Zhang, Daniel Ivanov, Ziyu Huang, Kate M MacDonald, Shane M Harding, Raquel Buj, Katherine M Aird, Jan H Beumer, Robert William Sobol, Christopher J Bakkenist
Deoxyuridine-rich cytoplasmic DNA antagonizes STING-dependent innate immune responses and sensitizes resistant tumors to anti-PD-L1 therapy. bioRxiv : the preprint server for biology (2024)
Shan Yan, Shobhan Gaddameedhi, Robert William Sobol
Inspiring basic and applied research in genome integrity mechanisms: Dedication to Samuel H. Wilson. Environmental and molecular mutagenesis (2024)
Shan Yan, Shobhan Gaddameedhi, Robert William Sobol
Inspiring basic and applied research in genome integrity mechanisms: Dedication to Samuel H. Wilson. Environmental and molecular mutagenesis (2024)
Shan Yan, Shobhan Gaddameedhi, Robert William Sobol
Inspiring basic and applied research in genome integrity mechanisms: Dedication to Samuel H. Wilson. Environmental and molecular mutagenesis (2024)
Rasha Q Al-Rahahleh, Kate M Saville, Joel F Andrews, Zhijin Wu, Christopher A Koczor, Robert William Sobol
Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA damage. bioRxiv : the preprint server for biology (2023)
Debanu Das, Matthew A J Duncton, Taxiarchis M Georgiadis, Patricia Pellicena, Jennifer Clark, Robert William Sobol, Millie M Georgiadis, John King-Underwood, David V Jobes, Caleb Chang, Yang Gao, Ashley M Deacon, David M Wilson
A New Drug Discovery Platform: Application to DNA Polymerase Eta and Apurinic/Apyrimidinic Endonuclease 1. International journal of molecular sciences 24 (23) (2023)
Rasha Q Al-Rahahleh, Kate M Saville, Joel F Andrews, Zhijin Wu, Christopher A Koczor, Robert William Sobol
Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA damage. bioRxiv : the preprint server for biology (2023)
Robert William Sobol
WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/mismatch repair deficiency. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Robert William Sobol
WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/mismatch repair deficiency. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Rasha Q Al-Rahahleh, Kate M Saville, Joel F Andrews, Zhijin Wu, Christopher A Koczor, Robert William Sobol
Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA damage. bioRxiv : the preprint server for biology (2023)
Robert William Sobol
WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/mismatch repair deficiency. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Robert William Sobol
WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/mismatch repair deficiency. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Robert William Sobol
WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/mismatch repair deficiency. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Robert William Sobol
WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/mismatch repair deficiency. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Robert William Sobol
WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/mismatch repair deficiency. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Rasha Q Al-Rahahleh, Kate M Saville, Joel F Andrews, Zhijin Wu, Christopher A Koczor, Robert William Sobol
Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA damage. bioRxiv : the preprint server for biology (2023)
Robert William Sobol
WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/mismatch repair deficiency. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Robert William Sobol
Editorial: DNA repair and nucleic acid therapeutics in cancer. NAR cancer 5 (3) (2023)
Robert William Sobol
WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/mismatch repair deficiency. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Robert William Sobol
WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/mismatch repair deficiency. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Jianfeng Li, Alison V Beiser, Nupur B Dey, Shunichi Takeda, Liton Kumar Saha, Kouji Hirota, L Lynette Parker, Mariah Carter, Martha I Arrieta, Robert William Sobol
A high-throughput 384-well CometChip platform reveals a role for 3-methyladenine in the cellular response to etoposide-induced DNA damage. NAR genomics and bioinformatics 4 (3) (2022)
Christopher A Koczor, Aaron J Haider, Kate M Saville, Jianfeng Li, Joel F Andrews, Alison V Beiser, Robert William Sobol
Live Cell Detection of Poly(ADP-Ribose) for Use in Genetic and Genotoxic Compound Screens. Cancers 14 (15) (2022)
Jianfeng Li, Christopher A Koczor, Kate M Saville, Faisal Hayat, Alison V Beiser, Steven McClellan, Marie E Migaud, Robert William Sobol
Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD + Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase. Cancers 14 (15) (2022)
Jianfeng Li, Silvia Garavaglia, Zhaofeng Ye, Andrea Moretti, Olga V Belyaeva, Alison Beiser, Md Ibrahim, Anna Wilk, Steve McClellan, Alla V Klyuyeva, Kelli R Goggans, Natalia Y Kedishvili, E Alan Salter, Andrzej Wierzbicki, Marie E Migaud, Steven J Mullett, Nathan A Yates, Carlos Jaime Camacho, Menico Rizzi, Robert William Sobol
A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells. Communications biology 4 (1) (2021)
Jung-Hyun Kim, Kyuho Jeong, Jianfeng Li, James M Murphy, Lana Vukadin, Joshua K Stone, Alexander Richard, Johnny Tran, G Yancey Gillespie, Erik K Flemington, Robert William Sobol, Ssang-Taek Steve Lim, Eun-Young Erin Ahn
SON drives oncogenic RNA splicing in glioblastoma by regulating PTBP1/PTBP2 switching and RBFOX2 activity. Nature communications 12 (1) (2021)
Jianfeng Li, Kate M Saville, Md Ibrahim, Xuemei Zeng, Steve McClellan, Anusha Angajala, Alison Beiser, Joel F Andrews, Mai Sun, Christopher A Koczor, Jennifer Clark, Faisal Hayat, Mikhail V Makarov, Anna Wilk, Nathan A Yates, Marie E Migaud, Robert William Sobol
NAD+ bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint and apoptosis in glioma stem cells. NAR cancer 3 (4) (2021)
Marlo K Thompson, Robert William Sobol, Aishwarya Prakash
Exploiting DNA Endonucleases to Advance Mechanisms of DNA Repair. Biology 10 (6) (2021)
Song My Hoang, Nicole Kaminski, Ragini Bhargava, Jonathan Barroso-González, Michelle L Lynskey, Laura García-Expósito, Justin L Roncaioli, Anne R Wondisford, Callen T Wallace, Simon C Watkins, Dominic I James, Ian D Waddell, Donald Ogilvie, Kate M Smith, Felipe da Veiga Leprevost, Dattatreya Mellacheruvu, Alexey I Nesvizhskii, Jianfeng Li, Dominique Ray-Gallet, Robert William Sobol, Geneviève Almouzni, Roderick J O'Sullivan
Regulation of ALT-associated homology-directed repair by polyADP-ribosylation. Nature structural & molecular biology 27 (12) (2020)
Anna Wilk, Faisal Hayat, Richard Cunningham, Jianfeng Li, Silvia Garavaglia, Leila Zamani, Davide M Ferraris, Peter Sykora, Joel Andrews, Jennifer Clark, Amanda Davis, Laurent Chaloin, Menico Rizzi, Marie Migaud, Robert William Sobol
Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity. Scientific reports 10 (1) (2020)
Pietro Mancuso, Rossella Tricarico, Vikram Bhattacharjee, Laura Cosentino, Yuwaraj Kadariya, Jaroslav Jelinek, Emmanuelle Nicolas, Margret Einarson, Neil Beeharry, Karthik Devarajan, Richard A Katz, Dorjbal G Dorjsuren, Hongmao Sun, Anton Simeonov, Antonio Giordano, Joseph R Testa, Guillaume Davidson, Irwin Davidson, Lionel Larue, Robert William Sobol, Timothy J Yen, Alfonso Bellacosa
Thymine DNA glycosylase as a novel target for melanoma. Oncogene 38 (19) (2019)
Peter Sykora, Ylenia Chiari, Andrew Heaton, Nickolas Moreno, Scott Glaberman, Robert William Sobol
Application of the CometChip platform to assess DNA damage in field-collected blood samples from turtles. Environmental and molecular mutagenesis 59 (4) (2018)
Peter Sykora, Kristine L Witt, Pooja Revanna, Stephanie L Smith-Roe, Jonathan Dismukes, Donald G Lloyd, Bevin P Engelward, Robert William Sobol
Next generation high throughput DNA damage detection platform for genotoxic compound screening. Scientific reports 8 (1) (2018)
Zixing Liu, Wenling Zhang, Joshua B Phillips, Ritu Arora, Steven McClellan, Jiangfeng Li, Jin-Hwan Kim, Robert William Sobol, Ming Tan
Immunoregulatory protein B7-H3 regulates cancer stem cell enrichment and drug resistance through MVP-mediated MEK activation. Oncogene 38 (1) (2018)
Manoj Sonavane, Peter Sykora, Joel F Andrews, Robert William Sobol, Natalie R Gassman
Camptothecin Efficacy to Poison Top1 Is Altered by Bisphenol A in Mouse Embryonic Fibroblasts. Chemical research in toxicology 31 (6) (2018)
Tyler Golato, Boris Brenerman, Daniel R McNeill, Jianfeng Li, Robert William Sobol, David M Wilson
Development of a Cell-Based Assay for Measuring Base Excision Repair Responses. Scientific reports 7 (1) (2017)
P Sykora, S Kanno, M Akbari, T Kulikowicz, B A Baptiste, G S Leandro, H Lu, J Tian, A May, K A Becker, D L Croteau, D M Wilson, Robert William Sobol, A Yasui, V A Bohr
DNA Polymerase Beta Participates in Mitochondrial DNA Repair. Molecular and cellular biology 37 (16) (2017)
Andrea Braganza, Jianfeng Li, Xuemei Zeng, Nathan A Yates, Nupur B Dey, Joel Andrews, Jennifer Clark, Leila Zamani, Xiao-Hong Wang, Claudette St Croix, Roderick O'Sullivan, Laura Garcia-Exposito, Jeffrey L Brodsky, Robert William Sobol
UBE3B Is a Calmodulin-regulated, Mitochondrion-associated E3 Ubiquitin Ligase. The Journal of biological chemistry 292 (6) (2016)
Elise Fouquerel, Justin Lormand, Arindam Bose, Hui-Ting Lee, Grace S Kim, Jianfeng Li, Robert William Sobol, Bret D Freudenthal, Sua Myong, Patricia L Opresko
Oxidative guanine base damage regulates human telomerase activity. Nature structural & molecular biology 23 (12) (2016)
Stephen K Godin, Zhuying Zhang, Benjamin W Herken, James W Westmoreland, Alison G Lee, Michael J Mihalevic, Zhongxun Yu, Robert William Sobol, Michael A Resnick, Kara A Bernstein
The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products. Nucleic acids research 44 (17) (2016)
Jason L Quiñones, Upasna Thapar, Kefei Yu, Qingming Fang, Robert William Sobol, Bruce Demple
Enzyme mechanism-based, oxidative DNA-protein cross-links formed with DNA polymerase β in vivo. Proceedings of the National Academy of Sciences of the United States of America 112 (28) (2015)

Robert William Sobol.css-eqlu8i{font-size:small;padding-left:4px;} (Robert W Sobol, R W Sobol)

Publication Activity (10 Years)

Top Topics

Top Venues

Robert William Sobol (Robert W Sobol, R W Sobol)