Roland Brosch

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 27

Top Topics

Escherichia Coli

Dendritic Cells

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Microbiology spectrum

Nature microbiology

This page only lists publications with an associated author ORCID identifier.

Publications

Camille Sous, Wafa Frigui, Alexandre Pawlik, Fadel Sayes, Laurence Ma, Thomas Cokelaer, Roland Brosch
Genomic and phenotypic characterization of Mycobacterium tuberculosis' closest-related non-tuberculous mycobacteria. Microbiology spectrum 12 (6) (2024)
Camille Sous, Wafa Frigui, Alexandre Pawlik, Fadel Sayes, Laurence Ma, Thomas Cokelaer, Roland Brosch
Genomic and phenotypic characterization of Mycobacterium tuberculosis' closest-related non-tuberculous mycobacteria. Microbiology spectrum 12 (6) (2024)
Mickael Orgeur, Camille Sous, Jan Madacki, Roland Brosch
Evolution and emergence of Mycobacterium tuberculosis. FEMS microbiology reviews 48 (2) (2024)
Camille Sous, Wafa Frigui, Alexandre Pawlik, Fadel Sayes, Laurence Ma, Thomas Cokelaer, Roland Brosch
Genomic and phenotypic characterization of Mycobacterium tuberculosis' closest-related non-tuberculous mycobacteria. Microbiology spectrum (2024)
Mickael Orgeur, Camille Sous, Jan Madacki, Roland Brosch
Evolution and emergence of Mycobacterium tuberculosis. FEMS microbiology reviews (2024)
Wladimir Malaga, Delphine Payros, Eva Meunier, Wafa Frigui, Fadel Sayes, Alexandre Pawlik, Mickael Orgeur, Céline Berrone, Flavie Moreau, Serge Mazères, Jesus Gonzalo-Asensio, David Rengel, Carlos Martin, Catherine Astarie-Dequeker, Lionel Mourey, Roland Brosch, Christophe Guilhot
Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli. PLoS pathogens 19 (7) (2023)
Poonam Chitale, Alexander D Lemenze, Emily C Fogarty, Avi Shah, Courtney Grady, Aubrey R Odom-Maybe, W Evan Johnson, Jason H Yang, A Murat Eren, Roland Brosch, Pradeep Kumar, David Alland
A comprehensive update to the Mycobacterium tuberculosis H37Rv reference genome. Nature communications 13 (1) (2022)
Poonam Chitale, Alexander D Lemenze, Emily C Fogarty, Avi Shah, Courtney Grady, Aubrey R Odom-Maybe, W Evan Johnson, Jason H Yang, A Murat Eren, Roland Brosch, Pradeep Kumar, David Alland
Author Correction: A comprehensive update to the Mycobacterium tuberculosis H37Rv reference genome. Nature communications 13 (1) (2022)
Morwan M Osman, Jonathan K Shanahan, Frances Chu, Kevin K Takaki, Malte L Pinckert, Antonio J Pagán, Roland Brosch, William H Conrad, Lalita Ramakrishnan
The C terminus of the mycobacterium ESX-1 secretion system substrate ESAT-6 is required for phagosomal membrane damage and virulence. Proceedings of the National Academy of Sciences of the United States of America 119 (11) (2022)
Sanne van der Niet, Maaike van Zon, Karin de Punder, Anita Grootemaat, Sofie Rutten, Simone J C F M Moorlag, Diane Houben, Astrid M van der Sar, Wilbert Bitter, Roland Brosch, Rogelio Hernandez Pando, Maria T Pena, Peter J Peters, Eric A Reits, Katrin D Mayer-Barber, Nicole N van der Wel
IL-1R1-Dependent Signals Improve Control of Cytosolic Virulent Mycobacteria In Vivo. mSphere 6 (3) (2021)
Jan Madacki, Mickael Orgeur, Guillem Mas Fiol, Wafa Frigui, Laurence Ma, Roland Brosch
ESX-1-Independent Horizontal Gene Transfer by Mycobacterium tuberculosis Complex Strains. mBio 12 (3) (2021)
Roxane Simeone, Fadel Sayes, Emeline Lawarée, Roland Brosch
Breaching the phagosome, the case of the tuberculosis agent. Cellular microbiology 23 (7) (2021)
Aideen C Allen, Wladimir Malaga, Cyril Gaudin, Arnaud Volle, Flavie Moreau, Ali Hassan, Catherine Astarie-Dequeker, Antonio Peixoto, Rudy Antoine, Alexandre Pawlik, Wafa Frigui, Céline Berrone, Roland Brosch, Philip Supply, Christophe Guilhot
Parallel in vivo experimental evolution reveals that increased stress resistance was key for the emergence of persistent tuberculosis bacilli. Nature microbiology 6 (8) (2021)
Visai Muruganandah, Harindra D Sathkumara, Saparna Pai, Catherine M Rush, Roland Brosch, Ashley J Waardenberg, Andreas Kupz
A systematic approach to simultaneously evaluate safety, immunogenicity, and efficacy of novel tuberculosis vaccination strategies. Science advances 6 (10) (2020)
Cyril Lefebvre, Wafa Frigui, Nawel Slama, Françoise Lauzeral-Vizcaino, Patricia Constant, Anne Lemassu, Tanya Parish, Nathalie Eynard, Mamadou Daffé, Roland Brosch, Annaïk Quémard
Discovery of a novel dehydratase of the fatty acid synthase type II critical for ketomycolic acid biosynthesis and virulence of Mycobacterium tuberculosis. Scientific reports 10 (1) (2020)
Daria Bottai, Wafa Frigui, Fadel Sayes, Mariagrazia Di Luca, Dalila Spadoni, Alexandre Pawlik, Marina Zoppo, Mickael Orgeur, Varun Khanna, David Hardy, Sophie Mangenot, Valerie Barbe, Claudine Medigue, Laurence Ma, Christiane Bouchier, Arianna Tavanti, Gerald Larrouy-Maumus, Roland Brosch
TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages. Nature communications 11 (1) (2020)
Violaine Dubois, Alexandre Pawlik, Anouchka Bories, Vincent Le Moigne, Odile Sismeiro, Rachel Legendre, Hugo Varet, María Del Pilar Rodríguez-Ordoñez, Jean-Louis Gaillard, Jean-Yves Coppée, Roland Brosch, Jean-Louis Herrmann, Fabienne Girard-Misguich
Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages. PLoS pathogens 15 (11) (2019)
Vera M Kroesen, Jan Madacki, Wafa Frigui, Fadel Sayes, Roland Brosch
Mycobacterial virulence: impact on immunogenicity and vaccine research. F1000Research 8 (2019)
Louis S Ates, Anzaan Dippenaar, Roy Ummels, Sander R Piersma, Aniek D van der Woude, Kim van der Kuij, Fabien Le Chevalier, Dulce Mata-Espinosa, Jorge Barrios-Payán, Brenda Marquina-Castillo, Carolina Guapillo, Connie R Jiménez, Arnab Pain, Edith N G Houben, Robin M Warren, Roland Brosch, Rogelio Hernández-Pando, Wilbert Bitter
Mutations in ppe38 block PE_PGRS secretion and increase virulence of Mycobacterium tuberculosis. Nature microbiology 3 (2) (2018)
Laura Laencina, Violaine Dubois, Vincent Le Moigne, Albertus Viljoen, Laleh Majlessi, Justin Pritchard, Audrey Bernut, Laura Piel, Anne-Laure Roux, Jean-Louis Gaillard, Bérengère Lombard, Damarys Loew, Eric J Rubin, Roland Brosch, Laurent Kremer, Jean-Louis Herrmann, Fabienne Girard-Misguich
Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus. Proceedings of the National Academy of Sciences of the United States of America 115 (5) (2018)
Louis S Ates, Fadel Sayes, Wafa Frigui, Roy Ummels, Merel P M Damen, Daria Bottai, Marcel A Behr, Jeroen W J van Heijst, Wilbert Bitter, Laleh Majlessi, Roland Brosch
RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection. PLoS pathogens 14 (6) (2018)
John D Blischak, Ludovic Tailleux, Marsha Myrthil, Cécile Charlois, Emmanuel Bergot, Aurélien Dinh, Gloria Morizot, Olivia Chény, Cassandre Von Platen, Jean-Louis Herrmann, Roland Brosch, Luis B Barreiro, Yoav Gilad
Predicting susceptibility to tuberculosis based on gene expression profiling in dendritic cells. Scientific reports 7 (1) (2017)
Florence Levillain, Yannick Poquet, Ludovic Mallet, Serge Mazères, Michael Marceau, Roland Brosch, Franz-Christoph Bange, Philip Supply, Axel Magalon, Olivier Neyrolles
Horizontal acquisition of a hypoxia-responsive molybdenum cofactor biosynthesis pathway contributed to Mycobacterium tuberculosis pathoadaptation. PLoS pathogens 13 (11) (2017)
Barbara Rieck, Giulia Degiacomi, Michael Zimmermann, Alessandro Cascioferro, Francesca Boldrin, Natalie R Lazar-Adler, Andrew R Bottrill, Fabien le Chevalier, Wafa Frigui, Marco Bellinzoni, María Natalia Lisa, Pedro M Alzari, Liem Nguyen, Roland Brosch, Uwe Sauer, Riccardo Manganelli, Helen M O'Hare
PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis. PLoS pathogens 13 (5) (2017)
William H Conrad, Morwan M Osman, Jonathan K Shanahan, Frances Chu, Kevin K Takaki, James Cameron, Digby Hopkinson-Woolley, Roland Brosch, Lalita Ramakrishnan
Mycobacterial ESX-1 secretion system mediates host cell lysis through bacterium contact-dependent gross membrane disruptions. Proceedings of the National Academy of Sciences of the United States of America 114 (6) (2017)
Eva C Boritsch, Wafa Frigui, Alessandro Cascioferro, Wladimir Malaga, Gilles Etienne, Françoise Laval, Alexandre Pawlik, Fabien Le Chevalier, Mickael Orgeur, Laurence Ma, Christiane Bouchier, Timothy P Stinear, Philip Supply, Laleh Majlessi, Mamadou Daffé, Christophe Guilhot, Roland Brosch
pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence. Nature microbiology 1 (2016)
Eva C Boritsch, Varun Khanna, Alexandre Pawlik, Nadine Honoré, Victor H Navas, Laurence Ma, Christiane Bouchier, Torsten Seemann, Philip Supply, Timothy P Stinear, Roland Brosch
Key experimental evidence of chromosomal DNA transfer among selected tuberculosis-causing mycobacteria. Proceedings of the National Academy of Sciences of the United States of America 113 (35) (2016)