Roosmarijn E. Vandenbroucke (Roos E Vandenbroucke, Roosmarijn E Vandenbroucke)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 44

Top Topics

Cerebrospinal Fluid

Inflammatory Response

Helicobacter Pylori

Top Venues

Journal of extracellular vesicles

Acta neuropathologica communications

Advanced healthcare materials

This page only lists publications with an associated author ORCID identifier.

Publications

Lien Van Hoecke, Roosmarijn E. Vandenbroucke
Beyond genetics: including the environmental dimension in amyloidosis mouse models for Alzheimer's disease. Acta neuropathologica communications 12 (1) (2024)
Simone Marcigaglia, Robin De Plus, Charysse Vandendriessche, Eleonore Schiltz, Marie-Lynn Cuypers, Jordi Cools, Luis D Hoffman, Roosmarijn E. Vandenbroucke, Maarten Dewilde, Sebastian Haesler
Microfluidic Interfaces for Chronic Bidirectional Access to the Brain. Advanced healthcare materials 13 (22) (2024)
Lien Van Hoecke, Roosmarijn E. Vandenbroucke
Beyond genetics: including the environmental dimension in amyloidosis mouse models for Alzheimer's disease. Acta neuropathologica communications 12 (1) (2024)
Lien Van Hoecke, Roosmarijn E. Vandenbroucke
Beyond genetics: including the environmental dimension in amyloidosis mouse models for Alzheimer's disease. Acta neuropathologica communications 12 (1) (2024)
Simone Marcigaglia, Robin De Plus, Charysse Vandendriessche, Eleonore Schiltz, Marie-Lynn Cuypers, Jordi Cools, Luis D Hoffman, Roosmarijn E. Vandenbroucke, Maarten Dewilde, Sebastian Haesler
Microfluidic Interfaces for Chronic Bidirectional Access to the Brain. Advanced healthcare materials (2024)
Lien Van Hoecke, Roosmarijn E. Vandenbroucke
Beyond genetics: including the environmental dimension in amyloidosis mouse models for Alzheimer's disease. Acta neuropathologica communications 12 (1) (2024)
Simone Marcigaglia, Robin De Plus, Charysse Vandendriessche, Eleonore Schiltz, Marie-Lynn Cuypers, Jordi Cools, Luis D Hoffman, Roosmarijn E. Vandenbroucke, Maarten Dewilde, Sebastian Haesler
Microfluidic Interfaces for Chronic Bidirectional Access to the Brain. Advanced healthcare materials (2024)
Junhua Xie, Lien Cools, Griet Van Imschoot, Elien Van Wonterghem, Marie J Pauwels, Ine Vlaeminck, Chloë De Witte, Samir El Andaloussi, Keimpe D B Wierda, Lies De Groef, Freddy Haesebrouck, Lien Van Hoecke, Roosmarijn E. Vandenbroucke
Helicobacter pylori-derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3-C3aR signalling. Journal of extracellular vesicles 12 (2) (2023)
Yael Hirschberg, Natalia Valle-Tamayo, Oriol Dols-Icardo, Sebastiaan Engelborghs, Bart Buelens, Roosmarijn E. Vandenbroucke, Yannick Vermeiren, Kurt Boonen, Inge Mertens
Proteomic comparison between non-purified cerebrospinal fluid and cerebrospinal fluid-derived extracellular vesicles from patients with Alzheimer's, Parkinson's and Lewy body dementia. Journal of extracellular vesicles 12 (12) (2023)
Junhua Xie, Lien Cools, Griet Van Imschoot, Elien Van Wonterghem, Marie J Pauwels, Ine Vlaeminck, Chloë De Witte, Samir El Andaloussi, Keimpe D B Wierda, Lies De Groef, Freddy Haesebrouck, Lien Van Hoecke, Roosmarijn E. Vandenbroucke
Helicobacter pylori-derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3-C3aR signalling. Journal of extracellular vesicles 12 (2) (2023)
Kasper Hobin, Marta Costas-Rodríguez, Elien Van Wonterghem, Roosmarijn E. Vandenbroucke, Frank Vanhaecke
Alzheimer's Disease and Age-Related Changes in the Cu Isotopic Composition of Blood Plasma and Brain Tissues of the APP NL-G-F Murine Model Revealed by Multi-Collector ICP-Mass Spectrometry. Biology 12 (6) (2023)
Junhua Xie, Lien Cools, Griet Van Imschoot, Elien Van Wonterghem, Marie J Pauwels, Ine Vlaeminck, Chloë De Witte, Samir El Andaloussi, Keimpe D B Wierda, Lies De Groef, Freddy Haesebrouck, Lien Van Hoecke, Roosmarijn E. Vandenbroucke
Helicobacter pylori-derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3-C3aR signalling. Journal of extracellular vesicles 12 (2) (2023)
Yael Hirschberg, Natalia Valle-Tamayo, Oriol Dols-Icardo, Sebastiaan Engelborghs, Bart Buelens, Roosmarijn E. Vandenbroucke, Yannick Vermeiren, Kurt Boonen, Inge Mertens
Proteomic comparison between non-purified cerebrospinal fluid and cerebrospinal fluid-derived extracellular vesicles from patients with Alzheimer's, Parkinson's and Lewy body dementia. Journal of extracellular vesicles 12 (12) (2023)
Yael Hirschberg, Natalia Valle-Tamayo, Oriol Dols-Icardo, Sebastiaan Engelborghs, Bart Buelens, Roosmarijn E. Vandenbroucke, Yannick Vermeiren, Kurt Boonen, Inge Mertens
Proteomic comparison between non-purified cerebrospinal fluid and cerebrospinal fluid-derived extracellular vesicles from patients with Alzheimer's, Parkinson's and Lewy body dementia. Journal of extracellular vesicles 12 (12) (2023)
Junhua Xie, Arnout Bruggeman, Clint De Nolf, Charysse Vandendriessche, Griet Van Imschoot, Elien Van Wonterghem, Lars Vereecke, Roosmarijn E. Vandenbroucke
Gut microbiota regulates blood-cerebrospinal fluid barrier function and Aβ pathology. The EMBO journal (2023)
Junhua Xie, Lien Cools, Griet Van Imschoot, Elien Van Wonterghem, Marie J Pauwels, Ine Vlaeminck, Chloë De Witte, Samir El Andaloussi, Keimpe D B Wierda, Lies De Groef, Freddy Haesebrouck, Lien Van Hoecke, Roosmarijn E. Vandenbroucke
Helicobacter pylori-derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3-C3aR signalling. Journal of extracellular vesicles 12 (2) (2023)
Yael Hirschberg, Natalia Valle-Tamayo, Oriol Dols-Icardo, Sebastiaan Engelborghs, Bart Buelens, Roosmarijn E. Vandenbroucke, Yannick Vermeiren, Kurt Boonen, Inge Mertens
Proteomic comparison between non-purified cerebrospinal fluid and cerebrospinal fluid-derived extracellular vesicles from patients with Alzheimer's, Parkinson's and Lewy body dementia. Journal of extracellular vesicles 12 (12) (2023)
Kasper Hobin, Marta Costas-Rodríguez, Elien Van Wonterghem, Roosmarijn E. Vandenbroucke, Frank Vanhaecke
Alzheimer's Disease and Age-Related Changes in the Cu Isotopic Composition of Blood Plasma and Brain Tissues of the APP NL-G-F Murine Model Revealed by Multi-Collector ICP-Mass Spectrometry. Biology 12 (6) (2023)
Lidia Yshii, Emanuela Pasciuto, Pascal Bielefeld, Loriana Mascali, Pierre Lemaitre, Marika Marino, James Dooley, Lubna Kouser, Stijn Verschoren, Vasiliki Lagou, Hannelore Kemps, Pascal Gervois, Antina de Boer, Oliver T Burton, Jérôme Wahis, Jens Verhaert, Samar H K Tareen, Carlos P Roca, Kailash Singh, Carly E Whyte, Axelle Kerstens, Zsuzsanna Callaerts-Vegh, Suresh Poovathingal, Teresa Prezzemolo, Keimpe Wierda, Amy Dashwood, Junhua Xie, Elien Van Wonterghem, Eline Creemers, Meryem Aloulou, Willy Gsell, Oihane Abiega, Sebastian Munck, Roosmarijn E. Vandenbroucke, Annelies Bronckaers, Robin Lemmens, Bart De Strooper, Ludo Van Den Bosch, Uwe Himmelreich, Carlos P Fitzsimons, Matthew G Holt, Adrian Liston
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation. Nature immunology 23 (6) (2022)
Lien Van Hoecke, Caroline Van Cauwenberghe, Stefania Bruno, Arnout Bruggeman, Jonas Castelein, Griet Van Imschoot, Elien Van Wonterghem, Robin Dittrich, Wouter Claeys, Junhua Xie, Bernd Giebel, Roosmarijn E. Vandenbroucke
Anti-Inflammatory Mesenchymal Stromal Cell-Derived Extracellular Vesicles Improve Pathology in Niemann-Pick Type C Disease. Biomedicines 9 (12) (2021)
Frederik Johannes Verweij, Leonora Balaj, Chantal M Boulanger, David R F Carter, Ewoud B Compeer, Gisela D'Angelo, Samir El Andaloussi, Jacky G Goetz, Julia Christina Gross, Vincent Hyenne, Eva-Maria Krämer-Albers, Charles Pin-Kuang Lai, Xavier Loyer, Alex Marki, Stefan Momma, Esther N M Nolte-'t Hoen, D Michiel Pegtel, Hector Peinado, Graça Raposo, Kirsi Rilla, Hidetoshi Tahara, Clotilde Théry, Martin E van Royen, Roosmarijn E. Vandenbroucke, Ann Marie Wehman, Kenneth Witwer, Zhiwei Wu, Richard W Wubbolts, Guillaume van Niel
The power of imaging to understand extracellular vesicle biology in vivo. Nature methods 18 (9) (2021)
Ana Rita Pombo Antunes, Isabelle Scheyltjens, Francesca Lodi, Julie Messiaen, Asier Antoranz, Johnny Duerinck, Daliya Kancheva, Liesbet Martens, Karen De Vlaminck, Hannah Van Hove, Signe Schmidt Kjølner Hansen, Francesca Maria Bosisio, Koen Van der Borght, Steven De Vleeschouwer, Raf M E Sciot, Luc Bouwens, Michiel Verfaillie, Niels Vandamme, Roosmarijn E. Vandenbroucke, Olivier De Wever, Yvan Saeys, Martin Guilliams, Conny Gysemans, Bart Neyns, Frederik De Smet, Diether Lambrechts, Jo A Van Ginderachter, Kiavash Movahedi
Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization. Nature neuroscience 24 (4) (2021)
Marlies Burgelman, Charysse Vandendriessche, Roosmarijn E. Vandenbroucke
Extracellular Vesicles: A Double-Edged Sword in Sepsis. Pharmaceuticals (Basel, Switzerland) 14 (8) (2021)
Helena Berlamont, Arnout Bruggeman, Eva Bauwens, Charysse Vandendriessche, Elien Clarebout, Junhua Xie, Sofie De Bruyckere, Griet Van Imschoot, Elien Van Wonterghem, Richard Ducatelle, Patrick Santens, Annemieke Smet, Freddy Haesebrouck, Roosmarijn E. Vandenbroucke
Gastric Helicobacter suis Infection Partially Protects against Neurotoxicity in A 6-OHDA Parkinson's Disease Mouse Model. International journal of molecular sciences 22 (21) (2021)
Charysse Vandendriessche, Sriram Balusu, Caroline Van Cauwenberghe, Marjana Brkic, Marie Pauwels, Nele Plehiers, Arnout Bruggeman, Pieter Dujardin, Griet Van Imschoot, Elien Van Wonterghem, An Hendrix, Femke Baeke, Riet De Rycke, Kris Gevaert, Roosmarijn E. Vandenbroucke
Importance of extracellular vesicle secretion at the blood-cerebrospinal fluid interface in the pathogenesis of Alzheimer's disease. Acta neuropathologica communications 9 (1) (2021)
Dhanu Gupta, Oscar P B Wiklander, Andre Görgens, Mariana Conceição, Giulia Corso, Xiuming Liang, Yiqi Seow, Sriram Balusu, Ulrika Feldin, R Beklem Bostancioglu, Rim Jawad, Doste R Mamand, Yi Xin Fiona Lee, Justin Hean, Imre Mäger, Thomas C Roberts, Manuela Gustafsson, Dara K Mohammad, Helena Sork, Alexandra Backlund, Per Lundin, Antonin de Fougerolles, Carl Inge Edvard Smith, Matthew John Andrew Wood, Roosmarijn E. Vandenbroucke, Joel Z Nordin, Samir El Andaloussi
Amelioration of systemic inflammation via the display of two different decoy protein receptors on extracellular vesicles. Nature biomedical engineering 5 (9) (2021)
Marie J Pauwels, Charysse Vandendriessche, Roosmarijn E. Vandenbroucke
Special delEVery: Extracellular Vesicles as Promising Delivery Platform to the Brain. Biomedicines 9 (11) (2021)
Helena Sork, Mariana Conceicao, Giulia Corso, Joel Nordin, Yi Xin Fiona Lee, Kaarel Krjutskov, Jakub Orzechowski Westholm, Pieter Vader, Marie Pauwels, Roosmarijn E. Vandenbroucke, Matthew Ja Wood, Samir El Andaloussi, Imre Mäger
Profiling of Extracellular Small RNAs Highlights a Strong Bias towards Non-Vesicular Secretion. Cells 10 (6) (2021)
Junhua Xie, Nina Gorlé, Charysse Vandendriessche, Griet Van Imschoot, Elien Van Wonterghem, Caroline Van Cauwenberghe, Eef Parthoens, Evelien Van Hamme, Saskia Lippens, Lien Van Hoecke, Roosmarijn E. Vandenbroucke
Low-grade peripheral inflammation affects brain pathology in the AppNL-G-Fmouse model of Alzheimer's disease. Acta neuropathologica communications 9 (1) (2021)
Charysse Vandendriessche, Arnout Bruggeman, Caroline Van Cauwenberghe, Roosmarijn E. Vandenbroucke
Extracellular Vesicles in Alzheimer's and Parkinson's Disease: Small Entities with Large Consequences. Cells 9 (11) (2020)
Ashley E Russell, Alexandra Sneider, Kennith W Witwer, Paolo Bergese, Suvendra N Bhattacharyya, Alexander Cocks, Emanuele Cocucci, Uta Erdbrügger, Juan M Falcon-Perez, David W Freeman, Thomas M Gallagher, Shuaishuai Hu, Yiyao Huang, Steven M Jay, Shin-Ichi Kano, Gregory Lavieu, Aleksandra Leszczynska, Alicia M Llorente, Quan Lu, Vasiliki Mahairaki, Dillon C Muth, Nicole Noren Hooten, Matias Ostrowski, Ilaria Prada, Susmita Sahoo, Tine Hiorth Schøyen, Lifu Sheng, Deanna Tesch, Guillaume Van Niel, Roosmarijn E. Vandenbroucke, Frederik J Verweij, Ana V Villar, Marca Wauben, Ann Marie Wehman, Hang Yin, David Raul Francisco Carter, Pieter Vader
Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop. Journal of extracellular vesicles 8 (1) (2019)
Zifu Zhong, João Paulo Portela Catani, Séan Mc Cafferty, Liesbeth Couck, Wim Van den Broeck, Nina Gorlé, Roosmarijn E. Vandenbroucke, Bert Devriendt, Sebastian Ulbert, Lieselotte Cnops, Johan Michels, Kevin K Ariën, Xiaole Cui
Immunogenicity and Protection Efficacy of a Naked Self-Replicating mRNA-Based Zika Virus Vaccine. Vaccines 7 (3) (2019)
Tinneke Delvaeye, Maarten A J De Smet, Stijn Verwaerde, Elke Decrock, Aleksandra Czekaj, Roosmarijn E. Vandenbroucke, Kelly Lemeire, Amanda Gonçalves, Wim Declercq, Peter Vandenabeele, Dmitri V Krysko, Luc Leybaert
Blocking connexin43 hemichannels protects mice against tumour necrosis factor-induced inflammatory shock. Scientific reports 9 (1) (2019)
Hannah Van Hove, Liesbet Martens, Isabelle Scheyltjens, Karen De Vlaminck, Ana Rita Pombo Antunes, Sofie De Prijck, Niels Vandamme, Sebastiaan De Schepper, Gert Van Isterdael, Charlotte L Scott, Jeroen Aerts, Geert Berx, Guy E Boeckxstaens, Roosmarijn E. Vandenbroucke, Lars Vereecke, Diederik Moechars, Martin Guilliams, Jo A Van Ginderachter, Yvan Saeys, Kiavash Movahedi
A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment. Nature neuroscience 22 (6) (2019)
Sophie Steeland, Nina Gorlé, Charysse Vandendriessche, Sriram Balusu, Marjana Brkic, Caroline Van Cauwenberghe, Griet Van Imschoot, Elien Van Wonterghem, Riet De Rycke, Anneke Kremer, Saskia Lippens, Edward Stopa, Conrad E Johanson, Claude Libert, Roosmarijn E. Vandenbroucke
Counteracting the effects of TNF receptor-1 has therapeutic potential in Alzheimer's disease. EMBO molecular medicine 10 (4) (2019)
Tjasa Lepko, Melanie Pusch, Tamara Müller, Dorothea Schulte, Janina Ehses, Michael A Kiebler, Julia Hasler, Hagen B Huttner, Roosmarijn E. Vandenbroucke, Charysse Vandendriessche, Miha Modic, Ana Martin-Villalba, Sheng Zhao, Enric LLorens-Bobadilla, Anja Schneider, Andre Fischer, Christopher T Breunig, Stefan H Stricker, Magdalena Götz, Jovica Ninkovic
Choroid plexus-derived miR-204 regulates the number of quiescent neural stem cells in the adult brain. The EMBO journal 38 (17) (2019)
Sarah Naessens, Julie De Zaeytijd, Delfien Syx, Roosmarijn E. Vandenbroucke, Frédéric Smeets, Caroline Van Cauwenbergh, Bart Peter Leroy, Frank Peelman, Frauke Coppieters
The N-terminal p.(Ser38Cys) TIMP3 mutation underlying Sorsby fundus dystrophy is a founder mutation disrupting an intramolecular disulfide bond. Human mutation 40 (5) (2019)
Sophie Steeland, Claude Libert, Roosmarijn E. Vandenbroucke
A New Venue of TNF Targeting. International journal of molecular sciences 19 (5) (2018)
Sofie Voet, Conor Mc Guire, Nora Hagemeyer, Arne Martens, Anna Schroeder, Peter Wieghofer, Carmen Daems, Ori Staszewski, Lieselotte Vande Walle, Marta Joana Costa Jordao, Mozes Sze, Hanna-Kaisa Vikkula, Delphine Demeestere, Griet Van Imschoot, Charlotte L Scott, Esther Hoste, Amanda Gonçalves, Martin Guilliams, Saskia Lippens, Claude Libert, Roosmarijn E. Vandenbroucke, Ki-Wook Kim, Steffen Jung, Zsuzsanna Callaerts-Vegh, Patrick Callaerts, Joris de Wit, Mohamed Lamkanfi, Marco Prinz, Geert van Loo
A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation. Nature communications 9 (1) (2018)
Roosmarijn E. Vandenbroucke
A Hidden Epithelial Barrier in the Brain with a Central Role in Regulating Brain Homeostasis. Implications for Aging. Annals of the American Thoracic Society (2017)
Ranhua Xiong, Roosmarijn E. Vandenbroucke, Katleen Broos, Toon Brans, Elien Van Wonterghem, Claude Libert, Jo Demeester, Stefaan C De Smedt, Kevin Braeckmans
Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability. Nature communications 7 (2016)
Sriram Balusu, Marjana Brkic, Claude Libert, Roosmarijn E. Vandenbroucke
The choroid plexus-cerebrospinal fluid interface in Alzheimer's disease: more than just a barrier. Neural regeneration research 11 (4) (2016)
Marjana Brkic, Sriram Balusu, Elien Van Wonterghem, Nina Gorlé, Iryna Benilova, Anna Kremer, Inge Van Hove, Lieve Moons, Bart De Strooper, Selma Kanazir, Claude Libert, Roosmarijn E. Vandenbroucke
Amyloid β Oligomers Disrupt Blood-CSF Barrier Integrity by Activating Matrix Metalloproteinases. The Journal of neuroscience : the official journal of the Society for Neuroscience 35 (37) (2016)
Sriram Balusu, Elien Van Wonterghem, Riet De Rycke, Koen Raemdonck, Stephan Stremersch, Kris Gevaert, Marjana Brkic, Delphine Demeestere, Valerie Vanhooren, An Hendrix, Claude Libert, Roosmarijn E. Vandenbroucke
Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles. EMBO molecular medicine 8 (10) (2016)
Lynda Grine, Lien Dejager, Claude Libert, Roosmarijn E. Vandenbroucke
Dual Inhibition of TNFR1 and IFNAR1 in Imiquimod-Induced Psoriasiform Skin Inflammation in Mice. Journal of immunology (Baltimore, Md. : 1950) 194 (11) (2015)