Nature biomedical engineering

Keyphrases

Publications

volume 8, number 3, 2024

Yunhua Shi, Daniel Reker, James D Byrne, Ameya R Kirtane, Kaitlyn Hess, Zhuyi Wang, Natsuda Navamajiti, Cameron C Young, Zachary Fralish, Zilu Zhang, Aaron Lopes, Vance Soares, Jacob Wainer, Thomas von Erlach, Lei Miao, Robert S Langer, Giovanni Traverso
Screening oral drugs for their interactions with the intestinal transportome via porcine tissue explants and machine learning. Nature biomedical engineering 8 (3) (2024)
Enrico Lugli, Mario Roederer, Rosa Sottile
Multipass high-dimensional flow cytometry. Nature biomedical engineering 8 (3) (2024)
Yunhua Shi, Daniel Reker, James D Byrne, Ameya R Kirtane, Kaitlyn Hess, Zhuyi Wang, Natsuda Navamajiti, Cameron C Young, Zachary Fralish, Zilu Zhang, Aaron Lopes, Vance Soares, Jacob Wainer, Thomas von Erlach, Lei Miao, Robert S Langer, Giovanni Traverso
Screening oral drugs for their interactions with the intestinal transportome via porcine tissue explants and machine learning. Nature biomedical engineering 8 (3) (2024)
Timothy A Whitehead
Deep screening of antibody-antigen affinities. Nature biomedical engineering 8 (3) (2024)
Alexis Autour, Christoph A Merten
Screening for drivers of SARS-CoV-2 uptake. Nature biomedical engineering 8 (3) (2024)
Weihua Guan
Probing when dCas9 tolerates DNA mismatches. Nature biomedical engineering 8 (3) (2024)

volume 8, number 4, 2024

Marta Buzzetti, Marco Gerlinger
Assessing the toxicity of bispecific antibodies. Nature biomedical engineering 8 (4) (2024)
Yiming Yin, Yan Guo, Yuxuan Jiang, Brian Quinlan, Haiyong Peng, Gogce Crynen, Wenhui He, Lizhou Zhang, Tianling Ou, Charles C Bailey, Michael Farzan
In vivo affinity maturation of mouse B cells reprogrammed to express human antibodies. Nature biomedical engineering 8 (4) (2024)
Olivia Sirpilla, R Leo Sakemura, Mehrdad Hefazi, Truc N Huynh, Ismail Can, James H Girsch, Erin E Tapper, Michelle J Cox, Kendall J Schick, Claudia Manriquez-Roman, Kun Yun, Carli M Stewart, Ekene J Ogbodo, Brooke L Kimball, Long K Mai, Omar L Gutierrez-Ruiz, Makena L Rodriguez, Martina Gluscevic, Daniel P Larson, Alex M Abel, Wesley A Wierson, Gloria Olivier, Elizabeth L Siegler, Saad Sirop Kenderian
Mesenchymal stromal cells with chimaeric antigen receptors for enhanced immunosuppression. Nature biomedical engineering 8 (4) (2024)
Wenchao Gu, Sijin Luozhong, Simian Cai, Ketaki Londhe, Nadine Elkasri, Robert Hawkins, Zhefan Yuan, Kai Su-Greene, Yujie Yin, Margaret Cruz, Yu-Wei Chang, Patrick McMullen, Chunyan Wu, Changwoo Seo, Akash Guru, Wenting Gao, Tara Sarmiento, Chris B Schaffer, Nozomi Nishimura, Richard Cerione, Qiuming Yu, Melissa Warden, Robert S Langer, Shaoyi Jiang
Extracellular vesicles incorporating retrovirus-like capsids for the enhanced packaging and systemic delivery of mRNA into neurons. Nature biomedical engineering 8 (4) (2024)
Yiming Yin, Yan Guo, Yuxuan Jiang, Brian Quinlan, Haiyong Peng, Gogce Crynen, Wenhui He, Lizhou Zhang, Tianling Ou, Charles C Bailey, Michael Farzan
In vivo affinity maturation of mouse B cells reprogrammed to express human antibodies. Nature biomedical engineering 8 (4) (2024)
Marta Buzzetti, Marco Gerlinger
Assessing the toxicity of bispecific antibodies. Nature biomedical engineering 8 (4) (2024)

volume 8, number 5, 2024

Zhuo Yang, Yingqin Hou, Geramie Grande, Jong Hyun Cho, Chao Wang, Yujie Shi, Jaroslav Zak, Yue Wan, Ke Qin, Dongfang Liu, John R Teijaro, Richard A Lerner, Peng Wu
Targeted desialylation and cytolysis of tumour cells by fusing a sialidase to a bispecific T-cell engager. Nature biomedical engineering 8 (5) (2024)
Michelle Z Dion, Natalie Artzi
Polypeptide agonists of innate immune sensors. Nature biomedical engineering 8 (5) (2024)
Michelle Z Dion, Natalie Artzi
Polypeptide agonists of innate immune sensors. Nature biomedical engineering 8 (5) (2024)
Zhuo Yang, Yingqin Hou, Geramie Grande, Jong Hyun Cho, Chao Wang, Yujie Shi, Jaroslav Zak, Yue Wan, Ke Qin, Dongfang Liu, John R Teijaro, Richard A Lerner, Peng Wu
Targeted desialylation and cytolysis of tumour cells by fusing a sialidase to a bispecific T-cell engager. Nature biomedical engineering 8 (5) (2024)
Ninad Kumbhojkar, Supriya Prakash, Tatsuya Fukuta, Kwasi Adu-Berchie, Neha Kapate, Rocky An, Solomina Darko, Vineeth Chandran Suja, Kyung Soo Park, Alexander P Gottlieb, Michael Griffith Bibbey, Malini Mukherji, Lily Li-Wen Wang, David J Mooney, Samir S Mitragotri
Neutrophils bearing adhesive polymer micropatches as a drug-free cancer immunotherapy. Nature biomedical engineering 8 (5) (2024)
Chenya Wang, Liping Zhong, Jiachen Xu, Qi Zhuang, Fei Gong, Xiaojing Chen, Huiquan Tao, Cong Hu, Fuquan Huang, Nailin Yang, Junyan Li, Qi Zhao, Xinjun Sun, Yu Huo, Qian Chen, Yongxiang Zhao, Rui Peng, Zhuang Liu
Oncolytic mineralized bacteria as potent locally administered immunotherapeutics. Nature biomedical engineering 8 (5) (2024)
DaeYong Lee, Kristin M Huntoon, Yifan Wang, Minjeong Kang, Yifei Lu, Seong Dong Jeong, Todd M Link, Thomas D Gallup, Yaqing Qie, Xuefeng Li, Shiyan Dong, Benjamin R Schrank, Adam J Grippin, Abin Antony, JongHoon Ha, Mengyu Chang, Yi An, Liang Wang, Dadi Jiang, Jing Li, Albert C Koong, John A Tainer, Wen Jiang, Yon Son Betty Kim
Synthetic cationic helical polypeptides for the stimulation of antitumour innate immune pathways in antigen-presenting cells. Nature biomedical engineering 8 (5) (2024)
Shijie Cao, Erica Budina, Michal M Raczy, Ani Solanki, Mindy Nguyen, Taryn N Beckman, Joseph W Reda, Kevin Hultgren, Phillip S Ang, Anna J Slezak, Lauren A Hesser, Aaron T Alpar, Kirsten C Refvik, Lucas S Shores, Ishita Pillai, Rachel P Wallace, Arjun Dhar, Elyse A Watkins, Jeffrey A Hubbell
A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice. Nature biomedical engineering 8 (5) (2024)
Shijie Cao, Erica Budina, Michal M Raczy, Ani Solanki, Mindy Nguyen, Taryn N Beckman, Joseph W Reda, Kevin Hultgren, Phillip S Ang, Anna J Slezak, Lauren A Hesser, Aaron T Alpar, Kirsten C Refvik, Lucas S Shores, Ishita Pillai, Rachel P Wallace, Arjun Dhar, Elyse A Watkins, Jeffrey A Hubbell
A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice. Nature biomedical engineering 8 (5) (2024)
Chenya Wang, Liping Zhong, Jiachen Xu, Qi Zhuang, Fei Gong, Xiaojing Chen, Huiquan Tao, Cong Hu, Fuquan Huang, Nailin Yang, Junyan Li, Qi Zhao, Xinjun Sun, Yu Huo, Qian Chen, Yongxiang Zhao, Rui Peng, Zhuang Liu
Oncolytic mineralized bacteria as potent locally administered immunotherapeutics. Nature biomedical engineering 8 (5) (2024)
Ninad Kumbhojkar, Supriya Prakash, Tatsuya Fukuta, Kwasi Adu-Berchie, Neha Kapate, Rocky An, Solomina Darko, Vineeth Chandran Suja, Kyung Soo Park, Alexander P Gottlieb, Michael Griffith Bibbey, Malini Mukherji, Lily Li-Wen Wang, David J Mooney, Samir S Mitragotri
Neutrophils bearing adhesive polymer micropatches as a drug-free cancer immunotherapy. Nature biomedical engineering 8 (5) (2024)
DaeYong Lee, Kristin M Huntoon, Yifan Wang, Minjeong Kang, Yifei Lu, Seong Dong Jeong, Todd M Link, Thomas D Gallup, Yaqing Qie, Xuefeng Li, Shiyan Dong, Benjamin R Schrank, Adam J Grippin, Abin Antony, JongHoon Ha, Mengyu Chang, Yi An, Liang Wang, Dadi Jiang, Jing Li, Albert C Koong, John A Tainer, Wen Jiang, Yon Son Betty Kim
Synthetic cationic helical polypeptides for the stimulation of antitumour innate immune pathways in antigen-presenting cells. Nature biomedical engineering 8 (5) (2024)
Shijie Cao, Erica Budina, Michal M Raczy, Ani Solanki, Mindy Nguyen, Taryn N Beckman, Joseph W Reda, Kevin Hultgren, Phillip S Ang, Anna J Slezak, Lauren A Hesser, Aaron T Alpar, Kirsten C Refvik, Lucas S Shores, Ishita Pillai, Rachel P Wallace, Arjun Dhar, Elyse A Watkins, Jeffrey A Hubbell
A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice. Nature biomedical engineering 8 (5) (2024)
Ningqiang Gong, Xuexiang Han, Lulu Xue, Margaret M Billingsley, Xisha Huang, Rakan El-Mayta, Jingya Qin, Neil C Sheppard, Carl H June, Michael J Mitchell
Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. Nature biomedical engineering 8 (5) (2024)
Shijie Cao, Erica Budina, Michal M Raczy, Ani Solanki, Mindy Nguyen, Taryn N Beckman, Joseph W Reda, Kevin Hultgren, Phillip S Ang, Anna J Slezak, Lauren A Hesser, Aaron T Alpar, Kirsten C Refvik, Lucas S Shores, Ishita Pillai, Rachel P Wallace, Arjun Dhar, Elyse A Watkins, Jeffrey A Hubbell
A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice. Nature biomedical engineering 8 (5) (2024)
Ningqiang Gong, Xuexiang Han, Lulu Xue, Margaret M Billingsley, Xisha Huang, Rakan El-Mayta, Jingya Qin, Neil C Sheppard, Carl H June, Michael J Mitchell
Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. Nature biomedical engineering 8 (5) (2024)
Shijie Cao, Erica Budina, Michal M Raczy, Ani Solanki, Mindy Nguyen, Taryn N Beckman, Joseph W Reda, Kevin Hultgren, Phillip S Ang, Anna J Slezak, Lauren A Hesser, Aaron T Alpar, Kirsten C Refvik, Lucas S Shores, Ishita Pillai, Rachel P Wallace, Arjun Dhar, Elyse A Watkins, Jeffrey A Hubbell
A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice. Nature biomedical engineering 8 (5) (2024)
DaeYong Lee, Kristin M Huntoon, Yifan Wang, Minjeong Kang, Yifei Lu, Seong Dong Jeong, Todd M Link, Thomas D Gallup, Yaqing Qie, Xuefeng Li, Shiyan Dong, Benjamin R Schrank, Adam J Grippin, Abin Antony, JongHoon Ha, Mengyu Chang, Yi An, Liang Wang, Dadi Jiang, Jing Li, Albert C Koong, John A Tainer, Wen Jiang, Yon Son Betty Kim
Synthetic cationic helical polypeptides for the stimulation of antitumour innate immune pathways in antigen-presenting cells. Nature biomedical engineering 8 (5) (2024)
Zhuo Yang, Yingqin Hou, Geramie Grande, Jong Hyun Cho, Chao Wang, Yujie Shi, Jaroslav Zak, Yue Wan, Ke Qin, Dongfang Liu, John R Teijaro, Richard A Lerner, Peng Wu
Targeted desialylation and cytolysis of tumour cells by fusing a sialidase to a bispecific T-cell engager. Nature biomedical engineering 8 (5) (2024)

volume 8, number 6, 2024

Jipeng Yan, Biao Huang, Johanna B Tonko, Matthieu Toulemonde, Joseph Hansen-Shearer, Qingyuan Tan, Kai Riemer, Konstantinos Ntagiantas, Rasheda A Chowdhury, Pier D Lambiase, Roxy Senior, Meng-Xing Tang
Transthoracic ultrasound localization microscopy of myocardial vasculature in patients. Nature biomedical engineering 8 (6) (2024)
Jipeng Yan, Biao Huang, Johanna B Tonko, Matthieu Toulemonde, Joseph Hansen-Shearer, Qingyuan Tan, Kai Riemer, Konstantinos Ntagiantas, Rasheda A Chowdhury, Pier D Lambiase, Roxy Senior, Meng-Xing Tang
Transthoracic ultrasound localization microscopy of myocardial vasculature in patients. Nature biomedical engineering 8 (6) (2024)
Mustafa Nasir-Moin, Lisa Irina Wadiura, Vlad Sacalean, Devin Juros, Misha Movahed-Ezazi, Emily K Lock, Andrew K Smith, Matthew D Lee, Hannah Weiss, Michael Müther, Daniel Alber, Sujay Ratna, Camila S Fang, Eric Suero-Molina, Sönke Hellwig, Walter Stummer, Karl Rössler, Johannes A Hainfellner, Georg Widhalm, Barbara Kiesel, David Reichert, Mario Mischkulnig, Rajan Jain, Jakob Straehle, Nicolas Neidert, Oliver Schnell, Juergen Beck, Jay Trautman, Steve Pastore, Donato Pacione, Dimitris Placantonakis, Eric Karl Oermann, John G Golfinos, Todd C Hollon, Matija Snuderl, Christian W Freudiger, Dieter Henrik Heiland, Daniel A Orringer
Localization of protoporphyrin IX during glioma-resection surgery via paired stimulated Raman histology and fluorescence microscopy. Nature biomedical engineering 8 (6) (2024)
Rongkang Gao, Zhiqiang Xu, Cheng-Bo Liu
Fast capturing of deep blood flow. Nature biomedical engineering 8 (6) (2024)
Jipeng Yan, Biao Huang, Johanna B Tonko, Matthieu Toulemonde, Joseph Hansen-Shearer, Qingyuan Tan, Kai Riemer, Konstantinos Ntagiantas, Rasheda A Chowdhury, Pier D Lambiase, Roxy Senior, Meng-Xing Tang
Transthoracic ultrasound localization microscopy of myocardial vasculature in patients. Nature biomedical engineering 8 (6) (2024)
Mustafa Nasir-Moin, Lisa Irina Wadiura, Vlad Sacalean, Devin Juros, Misha Movahed-Ezazi, Emily K Lock, Andrew K Smith, Matthew D Lee, Hannah Weiss, Michael Müther, Daniel Alber, Sujay Ratna, Camila S Fang, Eric Suero-Molina, Sönke Hellwig, Walter Stummer, Karl Rössler, Johannes A Hainfellner, Georg Widhalm, Barbara Kiesel, David Reichert, Mario Mischkulnig, Rajan Jain, Jakob Straehle, Nicolas Neidert, Oliver Schnell, Juergen Beck, Jay Trautman, Steve Pastore, Donato Pacione, Dimitris Placantonakis, Eric Karl Oermann, John G Golfinos, Todd C Hollon, Matija Snuderl, Christian W Freudiger, Dieter Henrik Heiland, Daniel A Orringer
Localization of protoporphyrin IX during glioma-resection surgery via paired stimulated Raman histology and fluorescence microscopy. Nature biomedical engineering 8 (6) (2024)
Robert Ohlendorf, Nan Li, Valerie Doan Phi Van, Miriam Schwalm, Yuting Ke, Miranda Dawson, Ying Jiang, Sayani Das, Brenna Stallings, Wen Ting Zheng, Alan Jasanoff
Imaging bioluminescence by detecting localized haemodynamic contrast from photosensitized vasculature. Nature biomedical engineering 8 (6) (2024)
Yuanlong Zhang, Lekang Yuan, Qiyu Zhu, Jiamin Wu, Tobias Nöbauer, Rujin Zhang, Guihua Xiao, Mingrui Wang, Hao Xie, Zengcai Guo, Qionghai Dai, Alipasha Vaziri
A miniaturized mesoscope for the large-scale single-neuron-resolved imaging of neuronal activity in freely behaving mice. Nature biomedical engineering 8 (6) (2024)
Qiang Feng, Zachary T Bennett, Anthony Grichuk, Raymundo Pantoja, Tongyi Huang, Brandon Faubert, Gang Huang, Mingyi Chen, Ralph J DeBerardinis, Baran D Sumer, Jinming Gao
Severely polarized extracellular acidity around tumour cells. Nature biomedical engineering 8 (6) (2024)

volume 8, number 7, 2024

Yufeng Li, Minkang Tan, Almira Akkari-Henić, Limin Zhang, Maarten Kip, Shengnan Sun, Jorian J Sepers, Ningning Xu, Yavuz Ariyurek, Susan L Kloet, Richard P Davis, Harald Mikkers, Joshua J Gruber, Michael Paul Snyder, Xiao Li, Baoxu Pang
Genome-wide Cas9-mediated screening of essential non-coding regulatory elements via libraries of paired single-guide RNAs. Nature biomedical engineering 8 (7) (2024)
Yufeng Li, Minkang Tan, Almira Akkari-Henić, Limin Zhang, Maarten Kip, Shengnan Sun, Jorian J Sepers, Ningning Xu, Yavuz Ariyurek, Susan L Kloet, Richard P Davis, Harald Mikkers, Joshua J Gruber, Michael Paul Snyder, Xiao Li, Baoxu Pang
Genome-wide Cas9-mediated screening of essential non-coding regulatory elements via libraries of paired single-guide RNAs. Nature biomedical engineering 8 (7) (2024)
Fangping Wan, Marcelo Der Torossian Torres, Jacqueline Peng, de la Fuente-Nunez Cesar
Deep-learning-enabled antibiotic discovery through molecular de-extinction. Nature biomedical engineering 8 (7) (2024)
Yufeng Li, Minkang Tan, Almira Akkari-Henić, Limin Zhang, Maarten Kip, Shengnan Sun, Jorian J Sepers, Ningning Xu, Yavuz Ariyurek, Susan L Kloet, Richard P Davis, Harald Mikkers, Joshua J Gruber, Michael Paul Snyder, Xiao Li, Baoxu Pang
Genome-wide Cas9-mediated screening of essential non-coding regulatory elements via libraries of paired single-guide RNAs. Nature biomedical engineering 8 (7) (2024)
Xiaofeng Wu, Weize Xu, Lulu Deng, Yue Li, Zhongchao Wang, Leqiang Sun, Anran Gao, Haoqi Wang, Xiaodan Yang, Chengchao Wu, Yanyan Zou, Keji Yan, Zhixiang Liu, Lingkai Zhang, Guohua Du, Liyao Yang, Da Lin, Junqiu Yue, Ping Wang, Yunyun Han, Zhenfang Fu, Jinxia Dai, Gang Cao
Spatial multi-omics at subcellular resolution via high-throughput in situ pairwise sequencing. Nature biomedical engineering 8 (7) (2024)
Yanmei Chen, Sisi Lin, Lu Wang, Yifan Zhang, Huan Chen, Zhenzhen Fu, Mengmeng Zhang, Huilong Luo, Jinyao Liu
Reinforcement of the intestinal mucosal barrier via mucus-penetrating PEGylated bacteria. Nature biomedical engineering 8 (7) (2024)
Yu Liu, Noah R Sundah, Nicholas R Y Ho, Wan Xiang Shen, Yun Xu, Auginia Natalia, Zhonglang Yu, Ju Ee Seet, Ching Wan Chan, Tze Ping Loh, Brian Y Lim, Huilin Shao
Bidirectional linkage of DNA barcodes for the multiplexed mapping of higher-order protein interactions in cells. Nature biomedical engineering 8 (7) (2024)
Justin R Randall, Luiz C Vieira, Claus O Wilke, Bryan W Davies
Deep mutational scanning and machine learning for the analysis of antimicrobial-peptide features driving membrane selectivity. Nature biomedical engineering 8 (7) (2024)
Fangping Wan, Marcelo Der Torossian Torres, Jacqueline Peng, de la Fuente-Nunez Cesar
Deep-learning-enabled antibiotic discovery through molecular de-extinction. Nature biomedical engineering 8 (7) (2024)
Fangping Wan, Marcelo Der Torossian Torres, Jacqueline Peng, de la Fuente-Nunez Cesar
Deep-learning-enabled antibiotic discovery through molecular de-extinction. Nature biomedical engineering 8 (7) (2024)