Shuo-Chien Ling

Publication Activity (10 Years)

Years Active: 2018-2022
Publications (10 Years): 16

Top Topics

Amyotrophic Lateral Sclerosis

Top Venues

The Journal of cell biology

Proceedings of the National Academy of Sciences of the United States of America

Acta neuropathologica communications

This page only lists publications with an associated author ORCID identifier.

Publications

Hayden Weng Siong Tan, Guang Lu, Han Dong, Yik-Lam Cho, Auginia Natalia, Liming Wang, Charlene Chan, Dennis Kappei, Reshma Taneja, Shuo-Chien Ling, Huilin Shao, Shih-Yin Tsai, Wen-Xing Ding, Han-Ming Shen
A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the mATG8-conjugation machinery. Nature communications 13 (1) (2022)
Ira Agrawal, Yong Shan Lim, Shi-Yan Ng, Shuo-Chien Ling
Deciphering lipid dysregulation in ALS: from mechanisms to translational medicine. Translational neurodegeneration 11 (1) (2022)
Wan Y Ho, Hannelore Hartmann, Shuo-Chien Ling
Central nervous system cholesterol metabolism in health and disease. IUBMB life 74 (8) (2022)
Zhi-Wei Zhang, Haitao Tu, Mei Jiang, Sarivin Vanan, Sook Yoong Chia, Se-Eun Jang, Wuan-Ting Saw, Zhi-Wei Ong, Dong-Rui Ma, Zhi-Dong Zhou, Jie Xu, Kai-Hua Guo, Wei-Ping Yu, Shuo-Chien Ling, Richard A Margolin, Daniel G Chain, Li Zeng, Eng-King Tan
The APP intracellular domain promotes LRRK2 expression to enable feed-forward neurodegenerative mechanisms in Parkinson's disease. Science signaling 15 (748) (2022)
Wan Yun Ho, Ira Agrawal, Sheue-Houy Tyan, Emma Sanford, Wei-Tang Chang, Kenneth Lim, Jolynn Ong, Bernice Siu Yan Tan, Aung Aung Kywe Moe, Regina Yu, Peiyan Wong, Greg Tucker-Kellogg, Edward Koo, Kai-Hsiang Chuang, Shuo-Chien Ling
Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits. Acta neuropathologica communications 9 (1) (2021)
Kae-Jiun Chang, Ira Agrawal, Anna Vainshtein, Wan Yun Ho, Wendy Xin, Greg Tucker-Kellogg, Keiichiro Susuki, Elior Peles, Shuo-Chien Ling, Jonah R Chan
TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells. eLife 10 (2021)
Wan Yun Ho, Jer-Cherng Chang, Kenneth Lim, Amaury Cazenave-Gassiot, Aivi T Nguyen, Juat Chin Foo, Sneha Muralidharan, Ashley Viera-Ortiz, Sarah J M Ong, Jin Hui Hor, Ira Agrawal, Shawn Hoon, Olubankole Aladesuyi Arogundade, Maria J Rodriguez, Su Min Lim, Seung Hyun Kim, John Ravits, Shi-Yan Ng, Markus R Wenk, Edward B Lee, Greg Tucker-Kellogg, Shuo-Chien Ling
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination. The Journal of cell biology 220 (9) (2021)
Hannelore Hartmann, Wan Yun Ho, Jer-Cherng Chang, Shuo-Chien Ling
Cholesterol dyshomeostasis in amyotrophic lateral sclerosis: cause, consequence, or epiphenomenon? The FEBS journal (2021)
Audrey Yi Tyan Peng, Ira Agrawal, Wan Yun Ho, Yi-Chun Yen, Ashley J Pinter, Jerry Liu, Qi Xuan Cheryl Phua, Katrianne Bethia Koh, Jer-Cherng Chang, Emma Sanford, Jodie Hon Kiu Man, Peiyan Wong, David H Gutmann, Greg Tucker-Kellogg, Shuo-Chien Ling
Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and triglial dysfunction. Proceedings of the National Academy of Sciences of the United States of America 117 (46) (2020)
Wan Yun Ho, Sheeja Navakkode, Fujia Liu, Tuck Wah Soong, Shuo-Chien Ling
Deregulated expression of a longevity gene, Klotho, in the C9orf72 deletion mice with impaired synaptic plasticity and adult hippocampal neurogenesis. Acta neuropathologica communications 8 (1) (2020)
Shuo-Chien Ling, Somasish Ghosh Dastidar, Seiya Tokunaga, Wan Yun Ho, Kenneth Lim, Hristelina Ilieva, Philippe A Parone, Sheue-Houy Tyan, Tsemay M Tse, Jer-Cherng Chang, Oleksandr Platoshyn, Ngoc B Bui, Anh Bui, Anne Vetto, Shuying Sun, Melissa McAlonis-Downes, Joo Seok Han, Debbie Swing, Katannya Kapeli, Gene W Yeo, Lino Tessarollo, Martin Marsala, Christopher E Shaw, Greg Tucker-Kellogg, Albert R La Spada, Clotilde Lagier-Tourenne, Sandrine Da Cruz, Don W Cleveland
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis. eLife 8 (2019)
Wan Yun Ho, Yee Kit Tai, Jer-Cherng Chang, Jason Liang, Sheue-Houy Tyan, Song Chen, Jun-Lin Guan, Huilin Zhou, Han-Ming Shen, Edward Koo, Shuo-Chien Ling
The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy. Autophagy 15 (5) (2019)
Wan Yun Ho, Shuo-Chien Ling
Elevated FUS levels by overriding its autoregulation produce gain-of-toxicity properties that disrupt protein and RNA homeostasis. Autophagy 15 (9) (2019)
Wen Lu, Margot Lakonishok, Anna S Serpinskaya, David Kirchenbüechler, Shuo-Chien Ling, Vladimir I Gelfand
Ooplasmic flow cooperates with transport and anchorage in Drosophila oocyte posterior determination. The Journal of cell biology 217 (10) (2018)
Shuo-Chien Ling
Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions. Neural plasticity 2018 (2018)
Jia Wang, Wan Yun Ho, Kenneth Lim, Jia Feng, Greg Tucker-Kellogg, Klaus-Armin Nave, Shuo-Chien Ling
Cell-autonomous requirement of TDP-43, an ALS/FTD signature protein, for oligodendrocyte survival and myelination. Proceedings of the National Academy of Sciences of the United States of America 115 (46) (2018)