Albert R La Spada

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 18

Top Topics

Genome Wide Association

Amyotrophic Lateral Sclerosis

Top Venues

Nature communications

bioRxiv : the preprint server for biology

Science translational medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Frederick J Arnold, Ya Cui, Sebastian Michels, Michael R Colwin, Cameron Stockford, Wenbin Ye, Oliver H Tam, Sneha Menon, Wendy G Situ, Kean C K Ehsani, Sierra Howard, Molly Gale Hammell, Weibo Xie, Albert R La Spada
TDP-43 dysregulation of polyadenylation site selection is a defining feature of RNA misprocessing in ALS/FTD and related disorders. bioRxiv : the preprint server for biology (2024)
Frederick J Arnold, Ya Cui, Sebastian Michels, Michael R Colwin, Cameron Stockford, Wenbin Ye, Oliver H Tam, Sneha Menon, Wendy G Situ, Kean C K Ehsani, Sierra Howard, Molly Gale Hammell, Weibo Xie, Albert R La Spada
TDP-43 dysregulation of polyadenylation site selection is a defining feature of RNA misprocessing in ALS/FTD and related disorders. bioRxiv : the preprint server for biology (2024)
Shiyi Wang, Ryan Baumert, Gabrielle Séjourné, Dhanesh Sivadasan Bindu, Kylie Dimond, Kristina Sakers, Leslie Vazquez, Jessica L Moore, Christabel Xin Tan, Tetsuya Takano, Maria Pia Rodriguez, Scott H Soderling, Albert R La Spada, Cagla Eroglu
Astrocytic LRRK2 Controls Synaptic Connectivity via Regulation of ERM Phosphorylation. bioRxiv : the preprint server for biology (2024)
Mary Rose Branch, Cynthia L Hsu, Kohta Ohnishi, Wen-Chuan Shen, Elian Lee, Jill Meisenhelder, Brett Winborn, Bryce L Sopher, J Paul Taylor, Tony Hunter, Albert R La Spada
MAP4K3 inhibits Sirtuin-1 to repress the LKB1-AMPK pathway to promote amino acid-dependent activation of the mTORC1 complex. Life science alliance 6 (8) (2023)
Ya Cui, Frederick J Arnold, Fanglue Peng, Dan Wang, Jason Sheng Li, Sebastian Michels, Eric J Wagner, Albert R La Spada, Weibo Xie
Alternative polyadenylation transcriptome-wide association study identifies APA-linked susceptibility genes in brain disorders. Nature communications 14 (1) (2023)
Ya Cui, Frederick J Arnold, Fanglue Peng, Dan Wang, Jason Sheng Li, Sebastian Michels, Eric J Wagner, Albert R La Spada, Weibo Xie
Alternative polyadenylation transcriptome-wide association study identifies APA-linked susceptibility genes in brain disorders. Nature communications 14 (1) (2023)
Ya Cui, Frederick J Arnold, Fanglue Peng, Dan Wang, Jason Sheng Li, Sebastian Michels, Eric J Wagner, Albert R La Spada, Weibo Xie
Alternative polyadenylation transcriptome-wide association study identifies APA-linked susceptibility genes in brain disorders. Nature communications 14 (1) (2023)
Anastasia Gromova, Byeonggu Cha, Erica M Robinson, Laura M Strickland, Nhat Nguyen, Mai K ElMallah, Constanza J Cortes, Albert R La Spada
X-linked SBMA model mice display relevant non-neurological phenotypes and their expression of mutant androgen receptor protein in motor neurons is not required for neuromuscular disease. Acta neuropathologica communications 11 (1) (2023)
Ya Cui, Frederick J Arnold, Fanglue Peng, Dan Wang, Jason Sheng Li, Sebastian Michels, Eric J Wagner, Albert R La Spada, Weibo Xie
Alternative polyadenylation transcriptome-wide association study identifies APA-linked susceptibility genes in brain disorders. Nature communications 14 (1) (2023)
Ya Cui, Frederick J Arnold, Fanglue Peng, Dan Wang, Jason Sheng Li, Sebastian Michels, Eric J Wagner, Albert R La Spada, Weibo Xie
Alternative polyadenylation transcriptome-wide association study identifies APA-linked susceptibility genes in brain disorders. Nature communications 14 (1) (2023)
Ya Cui, Frederick J Arnold, Fanglue Peng, Dan Wang, Jason Sheng Li, Sebastian Michels, Eric J Wagner, Albert R La Spada, Weibo Xie
Alternative polyadenylation transcriptome-wide association study identifies APA-linked susceptibility genes in brain disorders. Nature communications 14 (1) (2023)
Wooi Fang Lim, Mitra Forouhan, Thomas C Roberts, Jesse Dabney, Ruth Ellerington, Alfina A Speciale, Raquel Manzano, Maria Lieto, Gavinda Sangha, Subhashis Banerjee, Mariana Conceição, Lara Cravo, Annabelle Biscans, Loïc Roux, Naemeh Pourshafie, Christopher Grunseich, Stephanie Duguez, Anastasia Khvorova, Maria Pennuto, Constanza J Cortes, Albert R La Spada, Kenneth H Fischbeck, Matthew John Andrew Wood, Carlo Rinaldi
Gene therapy with AR isoform 2 rescues spinal and bulbar muscular atrophy phenotype by modulating AR transcriptional activity. Science advances 7 (34) (2021)
Chenchen Niu, Thazha P Prakash, Aneeza Kim, John L Quach, Laryssa A Huryn, Yuechen Yang, Edith Lopez, Ali Jazayeri, Gene Hung, Bryce L Sopher, Brian P Brooks, Eric E Swayze, C Frank Bennett, Albert R La Spada
Antisense oligonucleotides targeting mutant Ataxin-7 restore visual function in a mouse model of spinocerebellar ataxia type 7. Science translational medicine 10 (465) (2019)
Rui Gao, Anirban Chakraborty, Charlene Geater, Subrata Pradhan, Kara L Gordon, Jeffrey Snowden, Subo Yuan, Audrey S Dickey, Sanjeev Choudhary, Tetsuo Ashizawa, Lisa M Ellerby, Albert R La Spada, Leslie M Thompson, Tapas K Hazra, Partha S Sarkar
Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription. eLife 8 (2019)
Shuo-Chien Ling, Somasish Ghosh Dastidar, Seiya Tokunaga, Wan Yun Ho, Kenneth Lim, Hristelina Ilieva, Philippe A Parone, Sheue-Houy Tyan, Tsemay M Tse, Jer-Cherng Chang, Oleksandr Platoshyn, Ngoc B Bui, Anh Bui, Anne Vetto, Shuying Sun, Melissa McAlonis-Downes, Joo Seok Han, Debbie Swing, Katannya Kapeli, Gene W Yeo, Lino Tessarollo, Martin Marsala, Christopher E Shaw, Greg Tucker-Kellogg, Albert R La Spada, Clotilde Lagier-Tourenne, Sandrine Da Cruz, Don W Cleveland
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis. eLife 8 (2019)
Stephen K Gilmore-Hall, Jennifer Kuo, Jacqueline M Ward, Rabaab Zahra, Richard S Morrison, Guy A Perkins, Albert R La Spada
CCP1 promotes mitochondrial fusion and motility to prevent Purkinje cell neuron loss in pcd mice. The Journal of cell biology 218 (1) (2018)
Audrey S Dickey, Dafne N Sanchez, Martin A Villanueva, Kunal R Sampat, Weiwei Fan, Nicolas Arbez, Sergey Akimov, Michael J Van Kanegan, Kohta Ohnishi, Stephen K Gilmore-Hall, April L Flores, Janice M Nguyen, Nicole Lomas, Cynthia Li-Shin Hsu, Donald C Lo, Christopher A Ross, Eliezer Masliah, Ronald M Evans, Albert R La Spada
PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis. Science translational medicine 9 (419) (2018)
Audrey S Dickey, Albert R La Spada
Therapy development in Huntington disease: From current strategies to emerging opportunities. American journal of medical genetics. Part A 176 (4) (2017)