Si Ming Man

ResearcherID Scopus Author ID Scopus Author ID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 41

Top Venues

Nature communications

Nature immunology

Science advances

The EMBO journal

Australian National University

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Australian National University Jan 23 2017

Australia

Group Leader :: Department of Immunology and Infectious Disease

Education History

University of Cambridge

United Kingdom

PHD

Publications

Longjun Li, Rudi Mao, Shenli Yuan, Qingqing Xie, Jinyu Meng, Yu Gu, Siyu Tan, Xiaoqing Xu, Chengjiang Gao, Hongbin Liu, Chunhong Ma, Si Ming Man, Xiangbo Meng, Tao Xu, Xiao-Peng Qi
NCF4 attenuates colorectal cancer progression by modulating inflammasome activation and immune surveillance. Nature communications 15 (1) (2024)
Laurence Don Wai Luu, Abhimanu Pandey, Sudarshan Paramsothy, Chinh Ngo, Natalia Castaño-Rodríguez, Cheng Liu, Michael A Kamm, Thomas J Borody, Si Ming Man, Nadeem O Kaakoush
Profiling the colonic mucosal response to fecal microbiota transplantation identifies a role for GBP5 in colitis in humans and mice. Nature communications 15 (1) (2024)
Melkamu B Tessema, Shouya Feng, Daniel Enosi Tuipulotu, Rubaiyea Farrukee, Chinh Ngo, Catarina Gago da Graça, Masahiro Yamamoto, Daniel T Utzschneider, Andrew G Brooks, Sarah L Londrigan, Si Ming Man, Patrick C Reading
Mouse guanylate-binding proteins of the chromosome 3 cluster do not mediate antiviral activity in vitro or in mouse models of infection. Communications biology 7 (1) (2024)
Longjun Li, Rudi Mao, Shenli Yuan, Qingqing Xie, Jinyu Meng, Yu Gu, Siyu Tan, Xiaoqing Xu, Chengjiang Gao, Hongbin Liu, Chunhong Ma, Si Ming Man, Xiangbo Meng, Tao Xu, Xiao-Peng Qi
NCF4 attenuates colorectal cancer progression by modulating inflammasome activation and immune surveillance. Nature communications 15 (1) (2024)
Arti Medhavy, Vicki Athanasopoulos, Katharine Bassett, Yuke He, Maurice Stanley, Daniel Enosi Tuipulotu, Jean Cappello, Grant J Brown, Paula Gonzalez-Figueroa, Cynthia Turnbull, Somasundhari Shanmuganandam, Padmaja Tummala, Gemma Hart, Tom Lea-Henry, Hao Wang, Sonia Nambadan, Qian Shen, Jonathan A Roco, Gaetan Burgio, Phil Wu, Eun Cho, T Daniel Andrews, Matt A Field, Xiaoqian Wu, Huihua Ding, Qiang Guo, Nan Shen, Si Ming Man, Simon H Jiang, Matthew C Cook, Carola G Vinuesa
A TNIP1-driven systemic autoimmune disorder with elevated IgG4. Nature immunology 25 (9) (2024)
Yvette Wooff, Nilisha Fernando, Josephine H C Wong, Catherine Dietrich, Riemke Aggio-Bruce, Joshua A Chu-Tan, Avril A B Robertson, Sarah L Doyle, Si Ming Man, Riccardo Natoli
Author Correction: Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration. Scientific reports 14 (1) (2024)
Arti Medhavy, Vicki Athanasopoulos, Katharine Bassett, Yuke He, Maurice Stanley, Daniel Enosi Tuipulotu, Jean Cappello, Grant J Brown, Paula Gonzalez-Figueroa, Cynthia Turnbull, Somasundhari Shanmuganandam, Padmaja Tummala, Gemma Hart, Tom Lea-Henry, Hao Wang, Sonia Nambadan, Qian Shen, Jonathan A Roco, Gaetan Burgio, Phil Wu, Eun Cho, T Daniel Andrews, Matt A Field, Xiaoqian Wu, Huihua Ding, Qiang Guo, Nan Shen, Si Ming Man, Simon H Jiang, Matthew C Cook, Carola G Vinuesa
A TNIP1-driven systemic autoimmune disorder with elevated IgG4. Nature immunology 25 (9) (2024)
Melkamu B Tessema, Shouya Feng, Daniel Enosi Tuipulotu, Rubaiyea Farrukee, Chinh Ngo, Catarina Gago da Graça, Masahiro Yamamoto, Daniel T Utzschneider, Andrew G Brooks, Sarah L Londrigan, Si Ming Man, Patrick C Reading
Mouse guanylate-binding proteins of the chromosome 3 cluster do not mediate antiviral activity in vitro or in mouse models of infection. Communications biology 7 (1) (2024)
Abhimanu Pandey, Cheng Shen, Shouya Feng, Daniel Enosi Tuipulotu, Chinh Ngo, Cheng Liu, Melan Kurera, Anukriti Mathur, Shweta Venkataraman, Jing Zhang, Dipti Talaulikar, Renhua Song, Justin Jong-Leong Wong, Narci Teoh, Nadeem O Kaakoush, Si Ming Man
Ku70 senses cytosolic DNA and assembles a tumor-suppressive signalosome. Science advances 10 (4) (2024)
Longjun Li, Rudi Mao, Shenli Yuan, Qingqing Xie, Jinyu Meng, Yu Gu, Siyu Tan, Xiaoqing Xu, Chengjiang Gao, Hongbin Liu, Chunhong Ma, Si Ming Man, Xiangbo Meng, Tao Xu, Xiao-Peng Qi
NCF4 attenuates colorectal cancer progression by modulating inflammasome activation and immune surveillance. Nature communications 15 (1) (2024)
Poonam S Jadhav, Shreya Mahajan, Si Ming Man
NLRC5 PANoptosome: Aquaman of the Dead Sea. Cell research (2024)
Si Ming Man, Thirumala-Devi Kanneganti
Innate immune sensing of cell death in disease and therapeutics. Nature cell biology (2024)
Abhimanu Pandey, Cheng Shen, Shouya Feng, Daniel Enosi Tuipulotu, Chinh Ngo, Cheng Liu, Melan Kurera, Anukriti Mathur, Shweta Venkataraman, Jing Zhang, Dipti Talaulikar, Renhua Song, Justin Jong-Leong Wong, Narci Teoh, Nadeem O Kaakoush, Si Ming Man
Ku70 senses cytosolic DNA and assembles a tumor-suppressive signalosome. Science advances 10 (4) (2024)
Arti Medhavy, Vicki Athanasopoulos, Katharine Bassett, Yuke He, Maurice Stanley, Daniel Enosi Tuipulotu, Jean Cappello, Grant J Brown, Paula Gonzalez-Figueroa, Cynthia Turnbull, Somasundhari Shanmuganandam, Padmaja Tummala, Gemma Hart, Tom Lea-Henry, Hao Wang, Sonia Nambadan, Qian Shen, Jonathan A Roco, Gaetan Burgio, Phil Wu, Eun Cho, T Daniel Andrews, Matt A Field, Xiaoqian Wu, Huihua Ding, Qiang Guo, Nan Shen, Si Ming Man, Simon H Jiang, Matthew C Cook, Carola G Vinuesa
A TNIP1-driven systemic autoimmune disorder with elevated IgG4. Nature immunology (2024)
Arti Medhavy, Vicki Athanasopoulos, Katharine Bassett, Yuke He, Maurice Stanley, Daniel Enosi Tuipulotu, Jean Cappello, Grant J Brown, Paula Gonzalez-Figueroa, Cynthia Turnbull, Somasundhari Shanmuganandam, Padmaja Tummala, Gemma Hart, Tom Lea-Henry, Hao Wang, Sonia Nambadan, Qian Shen, Jonathan A Roco, Gaetan Burgio, Phil Wu, Eun Cho, T Daniel Andrews, Matt A Field, Xiaoqian Wu, Huihua Ding, Qiang Guo, Nan Shen, Si Ming Man, Simon H Jiang, Matthew C Cook, Carola G Vinuesa
A TNIP1-driven systemic autoimmune disorder with elevated IgG4. Nature immunology 25 (9) (2024)
Abhimanu Pandey, Cheng Shen, Shouya Feng, Daniel Enosi Tuipulotu, Chinh Ngo, Cheng Liu, Melan Kurera, Anukriti Mathur, Shweta Venkataraman, Jing Zhang, Dipti Talaulikar, Renhua Song, Justin Jong-Leong Wong, Narci Teoh, Nadeem O Kaakoush, Si Ming Man
Ku70 senses cytosolic DNA and assembles a tumor-suppressive signalosome. Science advances 10 (4) (2024)
Laurence Don Wai Luu, Abhimanu Pandey, Sudarshan Paramsothy, Chinh Ngo, Natalia Castaño-Rodríguez, Cheng Liu, Michael A Kamm, Thomas J Borody, Si Ming Man, Nadeem O Kaakoush
Profiling the colonic mucosal response to fecal microbiota transplantation identifies a role for GBP5 in colitis in humans and mice. Nature communications 15 (1) (2024)
Abhimanu Pandey, Cheng Shen, Shouya Feng, Daniel Enosi Tuipulotu, Chinh Ngo, Cheng Liu, Melan Kurera, Anukriti Mathur, Shweta Venkataraman, Jing Zhang, Dipti Talaulikar, Renhua Song, Justin Jong-Leong Wong, Narci Teoh, Nadeem O Kaakoush, Si Ming Man
Ku70 senses cytosolic DNA and assembles a tumor-suppressive signalosome. Science advances 10 (4) (2024)
Laurence Don Wai Luu, Abhimanu Pandey, Sudarshan Paramsothy, Chinh Ngo, Natalia Castaño-Rodríguez, Cheng Liu, Michael A Kamm, Thomas J Borody, Si Ming Man, Nadeem O Kaakoush
Profiling the colonic mucosal response to fecal microbiota transplantation identifies a role for GBP5 in colitis in humans and mice. Nature communications 15 (1) (2024)
Daniel Enosi Tuipulotu, Shouya Feng, Abhimanu Pandey, Anyang Zhao, Chinh Ngo, Anukriti Mathur, Jiwon Lee, Cheng Shen, Daniel R Fox, Yansong Xue, Callum Kay, Max Kirkby, Jordan Lo Pilato, Nadeem O Kaakoush, Daryl Webb, Melanie Rug, Avril Ab Robertson, Melkamu B Tessema, Stanley Pang, Daniel Degrandi, Klaus Pfeffer, Daria Augustyniak, Antje Blumenthal, Lisa A Miosge, Anne Brüstle, Masahiro Yamamoto, Patrick C Reading, Gaetan Burgio, Si Ming Man
Immunity against Moraxella catarrhalis requires guanylate-binding proteins and caspase-11-NLRP3 inflammasomes. The EMBO journal 42 (6) (2023)
Anukriti Mathur, Callum Kay, Yansong Xue, Abhimanu Pandey, Jiwon Lee, Weidong Jing, Daniel Enosi Tuipulotu, Jordan Lo Pilato, Shouya Feng, Chinh Ngo, Anyang Zhao, Cheng Shen, Melanie Rug, Lisa A Miosge, Ines I Atmosukarto, Jason D Price, Sidra A Ali, Elizabeth E Gardiner, Avril A B Robertson, Milena M Awad, Dena Lyras, Nadeem O Kaakoush, Si Ming Man
Clostridium perfringens virulence factors are nonredundant activators of the NLRP3 inflammasome. EMBO reports (2023)
Daniel Enosi Tuipulotu, Shouya Feng, Abhimanu Pandey, Anyang Zhao, Chinh Ngo, Anukriti Mathur, Jiwon Lee, Cheng Shen, Daniel R Fox, Yansong Xue, Callum Kay, Max Kirkby, Jordan Lo Pilato, Nadeem O Kaakoush, Daryl Webb, Melanie Rug, Avril Ab Robertson, Melkamu B Tessema, Stanley Pang, Daniel Degrandi, Klaus Pfeffer, Daria Augustyniak, Antje Blumenthal, Lisa A Miosge, Anne Brüstle, Masahiro Yamamoto, Patrick C Reading, Gaetan Burgio, Si Ming Man
Immunity against Moraxella catarrhalis requires guanylate-binding proteins and caspase-11-NLRP3 inflammasomes. The EMBO journal 42 (6) (2023)
Daniel Enosi Tuipulotu, Shouya Feng, Abhimanu Pandey, Anyang Zhao, Chinh Ngo, Anukriti Mathur, Jiwon Lee, Cheng Shen, Daniel R Fox, Yansong Xue, Callum Kay, Max Kirkby, Jordan Lo Pilato, Nadeem O Kaakoush, Daryl Webb, Melanie Rug, Avril Ab Robertson, Melkamu B Tessema, Stanley Pang, Daniel Degrandi, Klaus Pfeffer, Daria Augustyniak, Antje Blumenthal, Lisa A Miosge, Anne Brüstle, Masahiro Yamamoto, Patrick C Reading, Gaetan Burgio, Si Ming Man
Immunity against Moraxella catarrhalis requires guanylate-binding proteins and caspase-11-NLRP3 inflammasomes. The EMBO journal (2023)
Cynthia Turnbull, Josiah Bones, Maurice Stanley, Arti Medhavy, Hao Wang, Ayla May D Lorenzo, Jean Cappello, Somasundhari Shanmuganandam, Abhimanu Pandey, Sandali Seneviratne, Grant J Brown, Xiangpeng Meng, David Fulcher, Gaetan Burgio, Si Ming Man, Carmen de Lucas Collantes, Mercedes Gasior, Eduardo López Granados, Pilar Martin, Simon H Jiang, Matthew C Cook, Julia I Ellyard, Vicki Athanasopoulos, Ben Corry, Pablo F Cañete, Carola G Vinuesa
DECTIN-1: A modifier protein in CTLA-4 haploinsufficiency. Science advances 9 (49) (2023)
Daniel Enosi Tuipulotu, Shouya Feng, Abhimanu Pandey, Anyang Zhao, Chinh Ngo, Anukriti Mathur, Jiwon Lee, Cheng Shen, Daniel R Fox, Yansong Xue, Callum Kay, Max Kirkby, Jordan Lo Pilato, Nadeem O Kaakoush, Daryl Webb, Melanie Rug, Avril Ab Robertson, Melkamu B Tessema, Stanley Pang, Daniel Degrandi, Klaus Pfeffer, Daria Augustyniak, Antje Blumenthal, Lisa A Miosge, Anne Brüstle, Masahiro Yamamoto, Patrick C Reading, Gaetan Burgio, Si Ming Man
Immunity against Moraxella catarrhalis requires guanylate-binding proteins and caspase-11-NLRP3 inflammasomes. The EMBO journal 42 (6) (2023)
Weidong Jing, Jordan Lo Pilato, Callum Kay, Shouya Feng, Daniel Enosi Tuipulotu, Anukriti Mathur, Cheng Shen, Chinh Ngo, Anyang Zhao, Lisa A Miosge, Sidra Asad Ali, Elizabeth E Gardiner, Milena M Awad, Dena Lyras, Avril A B Robertson, Nadeem O Kaakoush, Si Ming Man
Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins. Science immunology 7 (71) (2022)
Shouya Feng, Daniel Enosi Tuipulotu, Abhimanu Pandey, Weidong Jing, Cheng Shen, Chinh Ngo, Melkamu B Tessema, Fei-Ju Li, Daniel R Fox, Anukriti Mathur, Anyang Zhao, Runli Wang, Klaus Pfeffer, Daniel Degrandi, Masahiro Yamamoto, Patrick C Reading, Gaetan Burgio, Si Ming Man
Pathogen-selective killing by guanylate-binding proteins as a molecular mechanism leading to inflammasome signaling. Nature communications 13 (1) (2022)
Si Ming Man, Brendan J Jenkins
Context-dependent functions of pattern recognition receptors in cancer. Nature reviews. Cancer 22 (7) (2022)
Weidong Jing, Jordan Lo Pilato, Callum Kay, Si Ming Man
Activation mechanisms of inflammasomes by bacterial toxins. Cellular microbiology 23 (4) (2021)
Yvette Wooff, Nilisha Fernando, Josephine H C Wong, Catherine Dietrich, Riemke Aggio-Bruce, Joshua A Chu-Tan, Avril A B Robertson, Sarah L Doyle, Si Ming Man, Riccardo Natoli
Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration. Scientific reports 10 (1) (2020)
Callum Kay, Runli Wang, Max Kirkby, Si Ming Man
Molecular mechanisms activating the NAIP-NLRC4 inflammasome: Implications in infectious disease, autoinflammation, and cancer. Immunological reviews 297 (1) (2020)
Cheng Shen, Abhimanu Pandey, Si Ming Man
Gasdermins deliver a deadly punch to cancer. Cell research 30 (6) (2020)
Shouya Feng, Si Ming Man
Captain GBP1: inflammasomes assemble, pyroptotic endgame. Nature immunology 21 (8) (2020)
Daniel R Fox, Si Ming Man
DDX3X: stressing the NLRP3 inflammasome. Cell research 29 (12) (2020)
Daniel R Fox, Anukriti Mathur, Yansong Xue, Yunqi Liu, Wei Hong Tan, Shouya Feng, Abhimanu Pandey, Chinh Ngo, Jenni A Hayward, Ines I Atmosukarto, Jason D Price, Matthew D Johnson, Nadja Jessberger, Avril A B Robertson, Gaetan Burgio, David Carl Tscharke, Edward M Fox, Denisse L Leyton, Nadeem O Kaakoush, Erwin P Maertlbauer, Stephen H Leppla, Si Ming Man
Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome. Nature communications 11 (1) (2020)
Yansong Xue, Si Ming Man
ALPK1: innate attraction to the sweetness of bacteria. Cell research 28 (12) (2019)
Si Ming Man
Inflammasomes in the gastrointestinal tract: infection, cancer and gut microbiota homeostasis. Nature reviews. Gastroenterology & hepatology 15 (12) (2019)
Jenni A Hayward, Anukriti Mathur, Chinh Ngo, Si Ming Man
Cytosolic Recognition of Microbes and Pathogens: Inflammasomes in Action. Microbiology and molecular biology reviews : MMBR 82 (4) (2018)
Anukriti Mathur, Shouya Feng, Jenni A Hayward, Chinh Ngo, Daniel Fox, Ines I Atmosukarto, Jason D Price, Kristina Schauer, Erwin Märtlbauer, Avril A B Robertson, Gaetan Burgio, Edward M Fox, Stephen H Leppla, Nadeem O Kaakoush, Si Ming Man
A multicomponent toxin from Bacillus cereus incites inflammation and shapes host outcome via the NLRP3 inflammasome. Nature microbiology 4 (2) (2018)
Chinh C Ngo, Si Ming Man
Mechanisms and functions of guanylate-binding proteins and related interferon-inducible GTPases: Roles in intracellular lysis of pathogens. Cellular microbiology 19 (12) (2017)
Xiaopeng Qi, Si Ming Man, R K Subbarao Malireddi, Rajendra Karki, Christopher Lupfer, Prajwal Gurung, Geoffrey A Neale, Clifford S Guy, Mohamed Lamkanfi, Thirumala-Devi Kanneganti
Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection. The Journal of experimental medicine 213 (10) (2016)
Nadeem O Kaakoush, Natalia Castaño-Rodríguez, Hazel M Mitchell, Si Ming Man
Global Epidemiology of Campylobacter Infection. Clinical microbiology reviews 28 (3) (2015)
Si Ming Man, Rajendra Karki, R K Subbarao Malireddi, Geoffrey Neale, Peter Vogel, Masahiro Yamamoto, Mohamed Lamkanfi, Thirumala-Devi Kanneganti
The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection. Nature immunology 16 (5) (2015)
Prajwal Gurung, Si Ming Man, Thirumala-Devi Kanneganti
A20 is a regulator of necroptosis. Nature immunology 16 (6) (2015)

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Publication Activity (10 Years)

Top Topics

Top Venues

Si Ming Man