Dena Lyras

Scopus Author ID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 20

Top Topics

Clostridium Difficile

Top Venues

Nature microbiology

Communications biology

Applied and environmental microbiology

Microbiology spectrum

This page only lists publications with an associated author ORCID identifier.

Publications

Milena M Awad, Chathura D Suraweera, Callum J Vidor, Auberon Y Ye-Lin, Galain C Williams, Steven J Mileto, Christopher K Barlow, Sheena McGowan, Dena Lyras
A Clostridioides difficile endolysin modulates toxin secretion without cell lysis. Communications biology 7 (1) (2024)
Milena M Awad, Chathura D Suraweera, Callum J Vidor, Auberon Y Ye-Lin, Galain C Williams, Steven J Mileto, Christopher K Barlow, Sheena McGowan, Dena Lyras
A Clostridioides difficile endolysin modulates toxin secretion without cell lysis. Communications biology 7 (1) (2024)
Anukriti Mathur, Callum Kay, Yansong Xue, Abhimanu Pandey, Jiwon Lee, Weidong Jing, Daniel Enosi Tuipulotu, Jordan Lo Pilato, Shouya Feng, Chinh Ngo, Anyang Zhao, Cheng Shen, Melanie Rug, Lisa A Miosge, Ines I Atmosukarto, Jason D Price, Sidra A Ali, Elizabeth E Gardiner, Avril A B Robertson, Milena M Awad, Dena Lyras, Nadeem O Kaakoush, Si Ming Man
Clostridium perfringens virulence factors are nonredundant activators of the NLRP3 inflammasome. EMBO reports (2023)
Sarah Larcombe, Galain C Williams, Jacob Amy, Su Chen Lim, Thomas V Riley, Anthony Muleta, Adele A Barugahare, David R Powell, Priscilla A Johanesen, Allen C Cheng, Anton Y Peleg, Dena Lyras
A genomic survey of Clostridioides difficile isolates from hospitalized patients in Melbourne, Australia. Microbiology spectrum (2023)
Sarah E Lucas, Sarah L Walton, Katrina M Mirabito Colafella, Steven J Mileto, Dena Lyras, Kate M Denton
Antihypertensives and Antibiotics: Impact on Intestinal Dysfunction and Hypertension. Hypertension (Dallas, Tex. : 1979) (2023)
Marijana Bosnjak, Avinash V Karpe, Thi Thu Hao Van, Despina Kotsanas, Grant A Jenkin, Samuel P Costello, Priscilla Johanesen, Robert J Moore, David J Beale, Yogitha N Srikhanta, Enzo A Palombo, Sarah Larcombe, Dena Lyras
Multi-omics analysis of hospital-acquired diarrhoeal patients reveals biomarkers of enterococcal proliferation and Clostridioides difficile infection. Nature communications 14 (1) (2023)
Mark A T Blaskovich, Karl A Hansford, Mark S Butler, Soumya Ramu, Angela M Kavanagh, Angie M Jarrad, Anggia Prasetyoputri, Miranda E Pitt, Johnny X Huang, Fredrik Lindahl, Zyta Maria Ziora, Tanya Bradford, Craig Muldoon, Premraj Rajaratnam, Ruby Pelingon, David J Edwards, Bing Zhang, Maite Amado, Alysha G Elliott, Johannes Zuegg, Lachlan J M Coin, Anne-Kathrin Woischnig, Nina Khanna, Elena Breidenstein, Anna Stincone, Clive S Mason, Nawaz Khan, Hye Kyung Cho, Melissa J Karau, Kerryl E Greenwood-Quaintance, Robin Patel, Mandy Wootton, Meagan L James, Melanie L Hutton, Dena Lyras, Abiodun David Ogunniyi, Layla K Mahdi, Darren J Trott, Xiaoqian Wu, Samantha Niles, Kim Lewis, Jordan R Smith, Katie E Barber, Juwon Yim, Seth Alan Rice, Michael Joseph Rybak, Chad R Ishmael, Kellyn R Hori, Nicholas M Bernthal, Kevin P Francis, Jason A Roberts, David L Paterson, Matthew A Cooper
A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science translational medicine 14 (662) (2022)
Ashleigh P Rogers, Steven J Mileto, Dena Lyras
Impact of enteric bacterial infections at and beyond the epithelial barrier. Nature reviews. Microbiology (2022)
Weidong Jing, Jordan Lo Pilato, Callum Kay, Shouya Feng, Daniel Enosi Tuipulotu, Anukriti Mathur, Cheng Shen, Chinh Ngo, Anyang Zhao, Lisa A Miosge, Sidra Asad Ali, Elizabeth E Gardiner, Milena M Awad, Dena Lyras, Avril A B Robertson, Nadeem O Kaakoush, Si Ming Man
Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins. Science immunology 7 (71) (2022)
Mark A T Blaskovich, Angela M Kavanagh, Alysha G Elliott, Bing Zhang, Soumya Ramu, Maite Amado, Gabrielle J Lowe, Alexandra O Hinton, Do Minh Thu Pham, Johannes Zuegg, Neil Beare, Diana Quach, Marc D Sharp, Joe Pogliano, Ashleigh P Rogers, Dena Lyras, Lendl Tan, Nicholas P West, David W Crawford, Marnie L Peterson, Matthew Callahan, Michael Thurn
The antimicrobial potential of cannabidiol. Communications biology 4 (1) (2021)
Ben Vezina, Theo Allnutt, Anthony L Keyburn, Ben Wade, Thi Thu Hao Van, Priscilla Johanesen, Dena Lyras, Robert J Moore
Stable Recombinant-Gene Expression from a Ligilactobacillus Live Bacterial Vector via Chromosomal Integration. Applied and environmental microbiology 87 (11) (2021)
Johana Luhur, Helena Chan, Benson Kachappilly, Ahmed M T Mohamed, Cécile Morlot, Milena Awad, Dena Lyras, Najwa Taib, Simonetta Gribaldo, David Z Rudner, Christopher D A Rodrigues
A dynamic, ring-forming MucB / RseB-like protein influences spore shape in Bacillus subtilis. PLoS genetics 16 (12) (2020)
Dena Lyras, Yogitha Srikhanta, Sheena McGowan
Reply to: Caution is warranted in using cephamycin antibiotics against recurrent Clostridioides difficile infection. Nature microbiology 5 (2) (2020)
Steven J Mileto, Thierry Jardé, Kevin O Childress, Jaime L Jensen, Ashleigh P Rogers, Genevieve Kerr, Melanie L Hutton, Michael J Sheedlo, Sarah C Bloch, John A Shupe, Katja Horvay, Tracey Flores, Rebekah M Engel, Simon Wilkins, Paul J McMurrick, Dana Borden Lacy, Helen E Abud, Dena Lyras
Clostridioides difficile infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease. Proceedings of the National Academy of Sciences of the United States of America 117 (14) (2020)
Lauren E Hartley-Tassell, Milena M Awad, Kate L Seib, Maria Scarselli, Silvana Savino, Joe Tiralongo, Dena Lyras, Christopher J Day, Michael P Jennings
Lectin Activity of the TcdA and TcdB Toxins of Clostridium difficile. Infection and immunity 87 (3) (2019)
Callum J Vidor, Dieter Bulach, Milena Awad, Dena Lyras
Paeniclostridium sordellii and Clostridioides difficile encode similar and clinically relevant tetracycline resistance loci in diverse genomic locations. BMC microbiology 19 (1) (2019)
Marietta John-White, James Gardiner, Priscilla Johanesen, Dena Lyras, Geoffrey J Dumsday
β-Aminopeptidases: Insight into Enzymes without a Known Natural Substrate. Applied and environmental microbiology 85 (15) (2019)
Yogitha N Srikhanta, Melanie L Hutton, Milena M Awad, Nyssa Drinkwater, Julie Singleton, Sophie L Day, Bliss A Cunningham, Sheena McGowan, Dena Lyras
Cephamycins inhibit pathogen sporulation and effectively treat recurrent Clostridioides difficile infection. Nature microbiology 4 (12) (2019)
Rebecca Rabi, Sarah Larcombe, Rommel A Mathias, Sheena McGowan, Milena Awad, Dena Lyras
Clostridium sordellii outer spore proteins maintain spore structural integrity and promote bacterial clearance from the gastrointestinal tract. PLoS pathogens 14 (4) (2018)
Jun Huang, Ciarán P Kelly, Kyriaki Bakirtzi, Javier A Villafuerte Gálvez, Dena Lyras, Steven J Mileto, Sarah Larcombe, Hua Xu, Xiaotong Yang, Kelsey S Shields, Weishu Zhu, Yi Zhang, Jeffrey D Goldsmith, Ishan J Patel, Joshua Hansen, Meijin Huang, Seppo Yla-Herttuala, Alan C Moss, Daniel Paredes-Sabja, Charalabos Pothoulakis, Yatrik M Shah, Jianping Wang, Xinhua Chen
Clostridium difficile toxins induce VEGF-A and vascular permeability to promote disease pathogenesis. Nature microbiology 4 (2) (2018)