Sian Xiao
ORCIDPublication Activity (10 Years)
Years Active: 2022-2023
Publications (10 Years): 13
Publications (10 Years): 13
Publications
- Sian Xiao, Mohammed Alshahrani, Grace Gupta, Peng Tao, Gennady M VerkhivkerMarkov State Models and Perturbation-Based Approaches Reveal Distinct Dynamic Signatures and Hidden Allosteric Pockets in the Emerging SARS-Cov-2 Spike Omicron Variant Complexes with the Host Receptor: The Interplay of Dynamics and Convergent Evolution Modulates Allostery and Functional Mechanisms. Journal of chemical information and modeling (2023)
- Mohammed Alshahrani, Grace Gupta, Sian Xiao, Peng Tao, Gennady M VerkhivkerComparative Analysis of Conformational Dynamics and Systematic Characterization of Cryptic Pockets in the SARS-CoV-2 Omicron BA.2, BA.2.75 and XBB.1 Spike Complexes with the ACE2 Host Receptor: Confluence of Binding and Structural Plasticity in Mediating Networks of Conserved Allosteric Sites. Viruses 15 (10) (2023)
- Gennady M Verkhivker, Mohammed Alshahrani, Grace Gupta, Sian Xiao, Peng TaoProbing Conformational Landscapes of Binding and Allostery in the SARS-CoV-2 Omicron Variant Complexes Using Microsecond Atomistic Simulations and Perturbation-Based Profiling Approaches: Hidden Role of Omicron Mutations as Modulators of Allosteric Signaling and Epistatic Relationships. bioRxiv : the preprint server for biology (2023)
- Gennady M Verkhivker, Mohammed Alshahrani, Grace Gupta, Sian Xiao, Peng TaoProbing conformational landscapes of binding and allostery in the SARS-CoV-2 omicron variant complexes using microsecond atomistic simulations and perturbation-based profiling approaches: hidden role of omicron mutations as modulators of allosteric signaling and epistatic relationships. Physical chemistry chemical physics : PCCP (2023)
- Gennady M Verkhivker, Mohammed Alshahrani, Grace Gupta, Sian Xiao, Peng Tao
- Gennady M Verkhivker, Mohammed Alshahrani, Grace Gupta, Sian Xiao, Peng TaoProbing Conformational Landscapes of Binding and Allostery in the SARS-CoV-2 Omicron Variant Complexes Using Microsecond Atomistic Simulations and Perturbation-Based Profiling Approaches: Hidden Role of Omicron Mutations as Modulators of Allosteric Signaling and Epistatic Relationships. bioRxiv : the preprint server for biology (2023)
- Gennady M Verkhivker, Mohammed Alshahrani, Grace Gupta, Sian Xiao, Peng Tao
- Mohammed Alshahrani, Grace Gupta, Sian Xiao, Peng Tao, Gennady M VerkhivkerExamining Functional Linkages Between Conformational Dynamics, Protein Stability and Evolution of Cryptic Binding Pockets in the SARS-CoV-2 Omicron Spike Complexes with the ACE2 Host Receptor: Recombinant Omicron Variants Mediate Variability of Conserved Allosteric Sites and Binding Epitopes. bioRxiv : the preprint server for biology (2023)
- Sian Xiao, Mohammed Alshahrani, Grace Gupta, Peng Tao, Gennady M VerkhivkerMarkov State Models and Perturbation-Based Approaches Reveal Distinct Dynamic Signatures and Hidden Allosteric Pockets in the Emerging SARS-Cov-2 Spike Omicron Variants Complexes with the Host Receptor: The Interplay of Dynamics and Convergent Evolution Modulates Allostery and Functional Mechanisms. bioRxiv : the preprint server for biology (2023)
- Haoxiang Li, Hao Tian, Yewei Chen, Sian Xiao, Xiu-Ying Zhao, Yangyang Gao, Liqun Zhang
- Nishank Raisinghani, Mohammed Alshahrani, Grace Gupta, Sian Xiao, Peng Tao, Gennady M VerkhivkerAccurate Characterization of Conformational Ensembles and Binding Mechanisms of the SARS-CoV-2 Omicron BA.2 and BA.2.86 Spike Protein with the Host Receptor and Distinct Classes of Antibodies Using AlphaFold2-Augmented Integrative Computational Modeling. bioRxiv : the preprint server for biology (2023)