Sigal Saphier

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 12

Top Topics

Molecularly Imprinted

Solid Phase Extraction

Molecular Dynamics

Top Venues

Journal of medicinal chemistry

Future medicinal chemistry

Communications chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Dina Yeffet, Ishay Columbus, Galit Parvari, Yoav Eichen, Sigal Saphier, Lee Ghindes-Azaria, Orit Redy-Keisar, Dafna Amir, Eyal Drug, Eytan Gershonov, Iris Binyamin, Yoram Cohen, Naama Karton-Lifshin, Yossi Zafrani
Addressing the Opioids Lipophilicity Challenge via a Straightforward and Simultaneous 1 H NMR-Based log P / D Determination, Both Separately and in Mixtures. Journal of medicinal chemistry 67 (14) (2024)
Dina Yeffet, Ishay Columbus, Galit Parvari, Yoav Eichen, Sigal Saphier, Lee Ghindes-Azaria, Orit Redy-Keisar, Dafna Amir, Eyal Drug, Eytan Gershonov, Iris Binyamin, Yoram Cohen, Naama Karton-Lifshin, Yossi Zafrani
Addressing the Opioids Lipophilicity Challenge via a Straightforward and Simultaneous 1 H NMR-Based log P / D Determination, Both Separately and in Mixtures. Journal of medicinal chemistry (2024)
Dina Yeffet, Ishay Columbus, Galit Parvari, Yoav Eichen, Sigal Saphier, Lee Ghindes-Azaria, Orit Redy-Keisar, Dafna Amir, Eyal Drug, Eytan Gershonov, Iris Binyamin, Yoram Cohen, Naama Karton-Lifshin, Yossi Zafrani
Addressing the Opioids Lipophilicity Challenge via a Straightforward and Simultaneous 1 H NMR-Based log P / D Determination, Both Separately and in Mixtures. Journal of medicinal chemistry 67 (14) (2024)
Dina Yeffet, Ishay Columbus, Galit Parvari, Yoav Eichen, Sigal Saphier, Lee Ghindes-Azaria, Orit Redy-Keisar, Dafna Amir, Eyal Drug, Eytan Gershonov, Iris Binyamin, Yoram Cohen, Naama Karton-Lifshin, Yossi Zafrani
Addressing the Opioids Lipophilicity Challenge via a Straightforward and Simultaneous 1 H NMR-Based log P / D Determination, Both Separately and in Mixtures. Journal of medicinal chemistry 67 (14) (2024)
Sigal Saphier, Yossi Zafrani
CF 2 H: a fascinating group for application in drug development enabling modulation of many molecular properties. Future medicinal chemistry 16 (12) (2024)
Sigal Saphier, Yossi Zafrani
CF 2 H: a fascinating group for application in drug development enabling modulation of many molecular properties. Future medicinal chemistry 16 (12) (2024)
Sigal Saphier, Yossi Zafrani
CF 2 H: a fascinating group for application in drug development enabling modulation of many molecular properties. Future medicinal chemistry 16 (12) (2024)
Ishay Columbus, Lee Ghindes-Azaria, Ido Michael Herzog, Eliav Blum, Galit Parvari, Yoav Eichen, Yoram Cohen, Eytan Gershonov, Eyal Drug, Sigal Saphier, Shlomi Elias, Boris Smolkin, Yossi Zafrani
Species-specific lipophilicities of fluorinated diketones in complex equilibria systems and their potential as multifaceted reversible covalent warheads. Communications chemistry 6 (1) (2023)
Ishay Columbus, Lee Ghindes-Azaria, Ravit Chen, Lea Yehezkel, Orit Redy-Keisar, Gil Fridkin, Dafna Amir, Daniele Marciano, Eyal Drug, Eytan Gershonov, Ziv Klausner, Sigal Saphier, Shlomi Elias, Alexander Pevzner, Yoav Eichen, Galit Parvari, Boris Smolkin, Yossi Zafrani
Studying Lipophilicity Trends of Phosphorus Compounds by 31 P-NMR Spectroscopy: A Powerful Tool for the Design of P-Containing Drugs. Journal of medicinal chemistry 65 (12) (2022)
Yossi Zafrani, Galit Parvari, Dafna Amir, Lee Ghindes-Azaria, Shlomi Elias, Alexander Pevzner, Gil Fridkin, Anat Berliner, Eytan Gershonov, Yoav Eichen, Sigal Saphier, Shahaf Katalan
Modulation of the H-Bond Basicity of Functional Groups by α-Fluorine-Containing Functions and its Implications for Lipophilicity and Bioisosterism. Journal of medicinal chemistry 64 (8) (2021)
Yossi Zafrani, Gali Sod-Moriah, Dina Yeffet, Anat Berliner, Dafna Amir, Daniele Marciano, Shlomi Elias, Shahaf Katalan, Nissan Ashkenazi, Moran Madmon, Eytan Gershonov, Sigal Saphier
CF2H, a Functional Group-Dependent Hydrogen-Bond Donor: Is It a More or Less Lipophilic Bioisostere of OH, SH, and CH3? Journal of medicinal chemistry 62 (11) (2019)
Yossi Zafrani, Dina Yeffet, Gali Sod-Moriah, Anat Berliner, Dafna Amir, Daniele Marciano, Eytan Gershonov, Sigal Saphier
Difluoromethyl Bioisostere: Examining the "Lipophilic Hydrogen Bond Donor" Concept. Journal of medicinal chemistry 60 (2) (2017)