Thomas Klose

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 52

Top Topics

Structural Basis

Electron Microscopy

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature structural & molecular biology

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Chen Sun, Pengwei Huang, Xueyong Xu, Frank S Vago, Kunpeng Li, Thomas Klose, Xi Jason Jiang, Wen Jiang
The 2.6 Å Structure of a Tulane Virus Variant with Minor Mutations Leading to Receptor Change. Biomolecules 14 (1) (2024)
Yu-Chen Yen, Yong Li, Chun-Liang Chen, Thomas Klose, Val J Watts, Carmen W Dessauer, John Joseph Grubb Tesmer
Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia. Nature structural & molecular biology (2024)
Yu-Chen Yen, Yong Li, Chun-Liang Chen, Thomas Klose, Val J Watts, Carmen W Dessauer, John Joseph Grubb Tesmer
Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia. Nature structural & molecular biology (2024)
Chun-Liang Chen, Ramizah Syahirah, Sandeep K Ravala, Yu-Chen Yen, Thomas Klose, Qing Deng, John Joseph Grubb Tesmer
Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ. Nature structural & molecular biology (2024)
Chun-Liang Chen, Ramizah Syahirah, Sandeep K Ravala, Yu-Chen Yen, Thomas Klose, Qing Deng, John Joseph Grubb Tesmer
Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ. Nature structural & molecular biology (2024)
Chun-Liang Chen, Ramizah Syahirah, Sandeep K Ravala, Yu-Chen Yen, Thomas Klose, Qing Deng, John Joseph Grubb Tesmer
Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ. Nature structural & molecular biology 31 (8) (2024)
Yu-Chen Yen, Yong Li, Chun-Liang Chen, Thomas Klose, Val J Watts, Carmen W Dessauer, John Joseph Grubb Tesmer
Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia. Nature structural & molecular biology (2024)
Yu-Chen Yen, Yong Li, Chun-Liang Chen, Thomas Klose, Val J Watts, Carmen W Dessauer, John Joseph Grubb Tesmer
Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia. Nature structural & molecular biology 31 (8) (2024)
Chen Sun, Pengwei Huang, Xueyong Xu, Frank S Vago, Kunpeng Li, Thomas Klose, Xi Jason Jiang, Wen Jiang
The 2.6 Å Structure of a Tulane Virus Variant with Minor Mutations Leading to Receptor Change. Biomolecules 14 (1) (2024)
Yu-Chen Yen, Yong Li, Chun-Liang Chen, Thomas Klose, Val J Watts, Carmen W Dessauer, John Joseph Grubb Tesmer
Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia. Nature structural & molecular biology (2024)
Chun-Liang Chen, Ramizah Syahirah, Sandeep K Ravala, Yu-Chen Yen, Thomas Klose, Qing Deng, John Joseph Grubb Tesmer
Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ. Nature structural & molecular biology 31 (8) (2024)
Yu-Chen Yen, Yong Li, Chun-Liang Chen, Thomas Klose, Val J Watts, Carmen W Dessauer, John Joseph Grubb Tesmer
Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia. Nature structural & molecular biology (2024)
Chen Sun, Pengwei Huang, Xueyong Xu, Frank S Vago, Kunpeng Li, Thomas Klose, Xi Jason Jiang, Wen Jiang
The 2.6 Å Structure of a Tulane Virus Variant with Minor Mutations Leading to Receptor Change. Biomolecules 14 (1) (2024)
Chun-Liang Chen, Ramizah Syahirah, Sandeep K Ravala, Yu-Chen Yen, Thomas Klose, Qing Deng, John Joseph Grubb Tesmer
Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ. Nature structural & molecular biology (2024)
Yu-Chen Yen, Yong Li, Chun-Liang Chen, Thomas Klose, Val J Watts, Carmen W Dessauer, John Joseph Grubb Tesmer
Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia. Nature structural & molecular biology 31 (8) (2024)
Chun-Liang Chen, Ramizah Syahirah, Sandeep K Ravala, Yu-Chen Yen, Thomas Klose, Qing Deng, John Joseph Grubb Tesmer
Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ. Nature structural & molecular biology 31 (8) (2024)
Chen Sun, Pengwei Huang, Xueyong Xu, Frank S Vago, Kunpeng Li, Thomas Klose, Xi Jason Jiang, Wen Jiang
The 2.6 Å Structure of a Tulane Virus Variant with Minor Mutations Leading to Receptor Change. Biomolecules 14 (1) (2024)
Yu-Chen Yen, Yong Li, Chun-Liang Chen, Thomas Klose, Val J Watts, Carmen W Dessauer, John Joseph Grubb Tesmer
Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia. Nature structural & molecular biology 31 (8) (2024)
Yu-Chen Yen, Yong Li, Chun-Liang Chen, Thomas Klose, Val J Watts, Carmen W Dessauer, John Joseph Grubb Tesmer
Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia. Nature structural & molecular biology 31 (8) (2024)
Chun-Liang Chen, Ramizah Syahirah, Sandeep K Ravala, Yu-Chen Yen, Thomas Klose, Qing Deng, John Joseph Grubb Tesmer
Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ. Nature structural & molecular biology 31 (8) (2024)
Kimberly A Dowd, Devika Sirohi, Scott D Speer, Laura A VanBlargan, Rita E Chen, Swati Mukherjee, Bradley M Whitener, Jennifer Govero, Maya A Aleshnick, Bridget Larman, Soila Sukupolvi-Petty, Madhumati Sevvana, Andrew S Miller, Thomas Klose, Ai-Hua Zheng, Scott Koenig, Margaret Kielian, Richard J Kuhn, Michael S. Diamond, Theodore C Pierson
prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
Kimberly A Dowd, Devika Sirohi, Scott D Speer, Laura A VanBlargan, Rita E Chen, Swati Mukherjee, Bradley M Whitener, Jennifer Govero, Maya A Aleshnick, Bridget Larman, Soila Sukupolvi-Petty, Madhumati Sevvana, Andrew S Miller, Thomas Klose, Ai-Hua Zheng, Scott Koenig, Margaret Kielian, Richard J Kuhn, Michael S. Diamond, Theodore C Pierson
prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
Kimberly A Dowd, Devika Sirohi, Scott D Speer, Laura A VanBlargan, Rita E Chen, Swati Mukherjee, Bradley M Whitener, Jennifer Govero, Maya A Aleshnick, Bridget Larman, Soila Sukupolvi-Petty, Madhumati Sevvana, Andrew S Miller, Thomas Klose, Ai-Hua Zheng, Scott Koenig, Margaret Kielian, Richard J Kuhn, Michael S. Diamond, Theodore C Pierson
prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
Lauren E Williamson, Abhishek Bandyopadhyay, Kevin Bailey, Devika Sirohi, Thomas Klose, Justin G Julander, Richard J Kuhn, James E Crowe
Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies. Proceedings of the National Academy of Sciences of the United States of America 120 (13) (2023)
Kimberly A Dowd, Devika Sirohi, Scott D Speer, Laura A VanBlargan, Rita E Chen, Swati Mukherjee, Bradley M Whitener, Jennifer Govero, Maya A Aleshnick, Bridget Larman, Soila Sukupolvi-Petty, Madhumati Sevvana, Andrew S Miller, Thomas Klose, Ai-Hua Zheng, Scott Koenig, Margaret Kielian, Richard J Kuhn, Michael S. Diamond, Theodore C Pierson
prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
Kimberly A Dowd, Devika Sirohi, Scott D Speer, Laura A VanBlargan, Rita E Chen, Swati Mukherjee, Bradley M Whitener, Jennifer Govero, Maya A Aleshnick, Bridget Larman, Soila Sukupolvi-Petty, Madhumati Sevvana, Andrew S Miller, Thomas Klose, Ai-Hua Zheng, Scott Koenig, Margaret Kielian, Richard J Kuhn, Michael S. Diamond, Theodore C Pierson
prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
Kimberly A Dowd, Devika Sirohi, Scott D Speer, Laura A VanBlargan, Rita E Chen, Swati Mukherjee, Bradley M Whitener, Jennifer Govero, Maya A Aleshnick, Bridget Larman, Soila Sukupolvi-Petty, Madhumati Sevvana, Andrew S Miller, Thomas Klose, Ai-Hua Zheng, Scott Koenig, Margaret Kielian, Richard J Kuhn, Michael S. Diamond, Theodore C Pierson
prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
Kimberly A Dowd, Devika Sirohi, Scott D Speer, Laura A VanBlargan, Rita E Chen, Swati Mukherjee, Bradley M Whitener, Jennifer Govero, Maya A Aleshnick, Bridget Larman, Soila Sukupolvi-Petty, Madhumati Sevvana, Andrew S Miller, Thomas Klose, Ai-Hua Zheng, Scott Koenig, Margaret Kielian, Richard J Kuhn, Michael S. Diamond, Theodore C Pierson
prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
Zhiqing Wang, Andrei Fokine, Xinwu Guo, Wen Jiang, Michael G Rossmann, Richard J Kuhn, Zhu-Hua Luo, Thomas Klose
Structure of Vibrio Phage XM1, a Simple Contractile DNA Injection Machine. Viruses 15 (8) (2023)
Kavita A Iyer, Yifan Hu, Thomas Klose, Takashi Murayama, Montserrat Samsó
Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM. Proceedings of the National Academy of Sciences of the United States of America 119 (30) (2022)
Chun-Liang Chen, Thomas Klose, Chengqun Sun, Arthur S Kim, Geeta Buda, Michael G Rossmann, Michael S Diamond, William B Klimstra, Richard J Kuhn
Cryo-EM structures of alphavirus conformational intermediates in low pH-triggered prefusion states. Proceedings of the National Academy of Sciences of the United States of America 119 (30) (2022)
Matthew R Vogt, Jianing Fu, Nurgun Kose, Lauren E Williamson, Robin Bombardi, Ian Setliff, Ivelin S Georgiev, Thomas Klose, Michael G Rossmann, Yury A Bochkov, James E Gern, Richard J Kuhn, James E Crowe
Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease. Science immunology 5 (49) (2022)
Qianqian Shao, Irina V Agarkova, Eric A Noel, David D Dunigan, Yunshu Liu, Aohan Wang, Mingcheng Guo, Linlin Xie, Xinyue Zhao, Michael G Rossmann, James L Van Van Etten, Thomas Klose, Qianglin Fang
Near-atomic, non-icosahedrally averaged structure of giant virus Paramecium bursaria chlorella virus 1. Nature communications 13 (1) (2022)
Qiuyan Chen, Manolo Plasencia, Zhuang Li, Somnath Mukherjee, Dhabaleswar Patra, Chun-Liang Chen, Thomas Klose, Xin-Qiu Yao, Anthony A Kossiakoff, Leifu Chang, Philip C Andrews, John Joseph Grubb Tesmer
Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1. Nature 595 (7868) (2021)
Baldeep Khare, Thomas Klose, Qianglin Fang, Michael G Rossmann, Richard J Kuhn
Structure of Usutu virus SAAR-1776 displays fusion loop asymmetry. Proceedings of the National Academy of Sciences of the United States of America 118 (34) (2021)
Runrun Wu, Jeremy W Bakelar, Karl Lundquist, Zijian Zhang, Katie M Kuo, David Ryoo, Yui Tik Pang, Chen Sun, Tommi A White, Thomas Klose, Wen Jiang, James C Gumbart, Nicholas Noinaj
Plasticity within the barrel domain of BamA mediates a hybrid-barrel mechanism by BAM. Nature communications 12 (1) (2021)
Chun-Liang Chen, S Saif Hasan, Thomas Klose, Yingyuan Sun, Geeta Buda, Chengqun Sun, William B Klimstra, Michael G Rossmann
Cryo-EM structure of eastern equine encephalitis virus in complex with heparan sulfate analogues. Proceedings of the National Academy of Sciences of the United States of America 117 (16) (2020)
Yingyuan Sun, Kelly Watters, Marchel G Hill, Qianglin Fang, Yue Liu, Richard J Kuhn, Thomas Klose, Michael G Rossmann, Ann C Palmenberg
Cryo-EM structure of rhinovirus C15a bound to its cadherin-related protein 3 receptor. Proceedings of the National Academy of Sciences of the United States of America 117 (12) (2020)
Xiansong Xiong, Chen Sun, Frank S Vago, Thomas Klose, Jiankang Zhu, Wen Jiang
Cryo-EM Structure of Heterologous Protein Complex Loaded Thermotoga Maritima Encapsulin Capsid. Biomolecules 10 (9) (2020)
Paulo V M Boratto, Graziele P Oliveira, Talita B Machado, Ana Cláudia S P Andrade, Jean-Pierre Baudoin, Thomas Klose, Frederik Schulz, Saïd Azza, Philippe Decloquement, Eric Chabrière, Philippe Colson, Anthony Levasseur, Bernard La Scola, Jonatas Santos Abrahao
Yaravirus: A novel 80-nm virus infecting Acanthamoeba castellanii. Proceedings of the National Academy of Sciences of the United States of America 117 (28) (2020)
Madhumati Sevvana, Thomas F Rogers, Andrew S Miller, Feng Long, Thomas Klose, Nathan Beutler, Yen-Chung Lai, Mara Parren, Laura M Walker, Geeta Buda, Dennis R Burton, Michael G Rossmann, Richard J Kuhn
Structural Basis of Zika Virus Specific Neutralization in Subsequent Flavivirus Infections. Viruses 12 (12) (2020)
Feng Long, Michael Doyle, Estefania Fernandez, Andrew S Miller, Thomas Klose, Madhumati Sevvana, Aubrey Bryan, Edgar Davidson, Benjamin J Doranz, Richard J Kuhn, Michael S Diamond, James E Crowe, Michael G Rossmann
Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope. Proceedings of the National Academy of Sciences of the United States of America 116 (5) (2019)
Koustav Maity, John M Heumann, Aaron P McGrath, Noah J Kopcho, Po-Kai Hsu, Chang-Wook Lee, James H Mapes, Denisse Garza, Srinivasan Krishnan, Garry P Morgan, Kevin J Hendargo, Thomas Klose, Steven D Rees, Arturo Medrano-Soto, Milton H Saier, Miguel Piñeros, Elizabeth A Komives, Julian I Schroeder, Geoffrey Chang, Michael H B Stowell
Cryo-EM structure of OSCA1.2 from Oryza sativa elucidates the mechanical basis of potential membrane hyperosmolality gating. Proceedings of the National Academy of Sciences of the United States of America 116 (28) (2019)
Neeti Ananthaswamy, Qianglin Fang, Wadad AlSalmi, Swati Jain, Zhenguo Chen, Thomas Klose, Yingyuan Sun, Yue Liu, Marthandan Mahalingam, Subhash Chand, Sodsai Tovanabutra, Merlin L Robb, Michael G Rossmann, Venigalla B Rao
A sequestered fusion peptide in the structure of an HIV-1 transmitted founder envelope trimer. Nature communications 10 (1) (2019)
Qianglin Fang, Dongjie Zhu, Irina Agarkova, Jagat Adhikari, Thomas Klose, Yue Liu, Zhenguo Chen, Yingyuan Sun, Michael L Gross, James L Van Etten, Xinzheng Zhang, Michael G Rossmann
Near-atomic structure of a giant virus. Nature communications 10 (1) (2019)
Matthew D Therkelsen, Thomas Klose, Frank Vago, Wen Jiang, Michael G Rossmann, Richard J Kuhn
Flaviviruses have imperfect icosahedral symmetry. Proceedings of the National Academy of Sciences of the United States of America 115 (45) (2018)
Yingyuan Sun, Aaron P Roznowski, Joshua M Tokuda, Thomas Klose, Alexander Mauney, Lois Pollack, Bentley A Fane, Michael G Rossmann
Structural changes of tailless bacteriophage ΦX174 during penetration of bacterial cell walls. Proceedings of the National Academy of Sciences of the United States of America 114 (52) (2017)
Vidya Mangala Prasad, Andrew S Miller, Thomas Klose, Devika Sirohi, Geeta Buda, Wen Jiang, Richard J Kuhn, Michael G Rossmann
Structure of the immature Zika virus at 9 Å resolution. Nature structural & molecular biology 24 (2) (2017)
S Saif Hasan, Andrew Miller, Gopal Sapparapu, Estefania Fernandez, Thomas Klose, Feng Long, Andrei Fokine, Jason C Porta, Wen Jiang, Michael S Diamond, James E Crowe, Richard J Kuhn, Michael G Rossmann
A human antibody against Zika virus crosslinks the E protein to prevent infection. Nature communications 8 (2017)
Moh Lan Yap, Thomas Klose, Akane Urakami, S Saif Hasan, Wataru Akahata, Michael G Rossmann
Structural studies of Chikungunya virus maturation. Proceedings of the National Academy of Sciences of the United States of America 114 (52) (2017)
Cristina De Castro, Thomas Klose, Immacolata Speciale, Rosa Lanzetta, Antonio Molinaro, James L Van Etten, Michael G Rossmann
Structure of the chlorovirus PBCV-1 major capsid glycoprotein determined by combining crystallographic and carbohydrate molecular modeling approaches. Proceedings of the National Academy of Sciences of the United States of America 115 (1) (2017)
Vidya Mangala Prasad, Thomas Klose, Michael G Rossmann
Assembly, maturation and three-dimensional helical structure of the teratogenic rubella virus. PLoS pathogens 13 (6) (2017)