Timothy L Downing

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 19

Top Venues

University of California Irvine

University of California Berkeley (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of California Irvine

United States

Assistant Professor :: Biomedical Engineering

Harvard University

United States

Postdoc :: Stem Cell and Regenerative Biology

Broad Institute

United States

Postdoc :: Epigenomics

Education History

University of California Berkeley

United States

PHD :: Bioengineering

Northwestern University

United States

BSC :: Chemical Engineering

Publications

Yang Song, Jennifer Soto, Sze Yue Wong, Yifan Wu, Tyler Hoffman, Navied Akhtar, Sam Norris, Julia Chu, Hyungju Park, Douglas O Kelkhoff, Cheen Euong Ang, Marius Wernig, Andrea M Kasko, Timothy L Downing, Mu-Ming Poo, Song Li
Biphasic regulation of epigenetic state by matrix stiffness during cell reprogramming. Science advances 10 (7) (2024)
Yang Song, Jennifer Soto, Sze Yue Wong, Yifan Wu, Tyler Hoffman, Navied Akhtar, Sam Norris, Julia Chu, Hyungju Park, Douglas O Kelkhoff, Cheen Euong Ang, Marius Wernig, Andrea M Kasko, Timothy L Downing, Mu-Ming Poo, Song Li
Biphasic regulation of epigenetic state by matrix stiffness during cell reprogramming. Science advances 10 (7) (2024)
Yang Song, Jennifer Soto, Sze Yue Wong, Yifan Wu, Tyler Hoffman, Navied Akhtar, Sam Norris, Julia Chu, Hyungju Park, Douglas O Kelkhoff, Cheen Euong Ang, Marius Wernig, Andrea M Kasko, Timothy L Downing, Mu-Ming Poo, Song Li
Biphasic regulation of epigenetic state by matrix stiffness during cell reprogramming. Science advances 10 (7) (2024)
Yang Song, Jennifer Soto, Sze Yue Wong, Yifan Wu, Tyler Hoffman, Navied Akhtar, Sam Norris, Julia Chu, Hyungju Park, Douglas O Kelkhoff, Cheen Euong Ang, Marius Wernig, Andrea M Kasko, Timothy L Downing, Mu-Ming Poo, Song Li
Biphasic regulation of epigenetic state by matrix stiffness during cell reprogramming. Science advances 10 (7) (2024)
Yang Song, Jennifer Soto, Sze Yue Wong, Yifan Wu, Tyler Hoffman, Navied Akhtar, Sam Norris, Julia Chu, Hyungju Park, Douglas O Kelkhoff, Cheen Euong Ang, Marius Wernig, Andrea M Kasko, Timothy L Downing, Mu-Ming Poo, Song Li
Biphasic regulation of epigenetic state by matrix stiffness during cell reprogramming. Science advances 10 (7) (2024)
Lauren A Urban, Jiachun Li, Gokhan Gundogdu, Annie Trinh, Hanjuan Shao, Travis Nguyen, Joshua R Mauney, Timothy L Downing
DNA Methylation Dynamics During Esophageal Epithelial Regeneration Following Repair with Acellular Silk Fibroin Grafts in Rat. Advanced biology (2023)
Vijaykumar S Meli, Praveen Krishna Veerasubramanian, Timothy L Downing, Wenqi Wang, Wendy F Liu
Mechanosensation to inflammation: Roles for YAP/TAZ in innate immune cells. Science signaling 16 (783) (2023)
Lauren A Urban, Jiachun Li, Gokhan Gundogdu, Annie Trinh, Hanjuan Shao, Travis Nguyen, Joshua R Mauney, Timothy L Downing
DNA Methylation Dynamics During Esophageal Epithelial Regeneration Following Repair with Acellular Silk Fibroin Grafts in Rat. Advanced biology (2023)
Vijaykumar S Meli, Praveen Krishna Veerasubramanian, Timothy L Downing, Wenqi Wang, Wendy F Liu
Mechanosensation to inflammation: Roles for YAP/TAZ in innate immune cells. Science signaling 16 (783) (2023)
Lauren A Urban, Jiachun Li, Gokhan Gundogdu, Annie Trinh, Hanjuan Shao, Travis Nguyen, Joshua R Mauney, Timothy L Downing
DNA Methylation Dynamics During Esophageal Epithelial Regeneration Following Repair with Acellular Silk Fibroin Grafts in Rat. Advanced biology (2023)
Lauren A Urban, Jiachun Li, Gokhan Gundogdu, Annie Trinh, Hanjuan Shao, Travis Nguyen, Joshua R Mauney, Timothy L Downing
DNA Methylation Dynamics During Esophageal Epithelial Regeneration Following Repair with Acellular Silk Fibroin Grafts in Rat. Advanced biology (2023)
Annie Trinh, Yi Huang, Hanjuan Shao, Aparna Ram, Julien L P Morival, Jonathan Wang, Eun Ji Chung, Timothy L Downing
Targeting the ADPKD methylome using nanoparticle-mediated combination therapy. APL bioengineering 7 (2) (2023)
Lauren A Urban, Jiachun Li, Gokhan Gundogdu, Annie Trinh, Hanjuan Shao, Travis Nguyen, Joshua R Mauney, Timothy L Downing
DNA Methylation Dynamics During Esophageal Epithelial Regeneration Following Repair with Acellular Silk Fibroin Grafts in Rat. Advanced biology (2023)
Timothy L Downing
Towards spheroid-omics. Nature methods 18 (11) (2021)
Praveen Krishna Veerasubramanian, Victor C Joe, Wendy F Liu, Timothy L Downing
Characterization of Macrophage and Cytokine Interactions with Biomaterials Used in Negative-Pressure Wound Therapy. Bioengineering (Basel, Switzerland) 9 (1) (2021)
Julien L P Morival, Halida P Widyastuti, Cecilia H H Nguyen, Michael V Zaragoza, Timothy L Downing
DNA methylation analysis reveals epimutation hotspots in patients with dilated cardiomyopathy-associated laminopathies. Clinical epigenetics 13 (1) (2021)
Luis Busto-Moner, Julien L P Morival, Honglei Ren, Arjang Fahim, Zachary Reitz, Timothy L Downing, Elizabeth L Read
Stochastic modeling reveals kinetic heterogeneity in post-replication DNA methylation. PLoS computational biology 16 (4) (2020)
Vijaykumar S Meli, Hamza Atcha, Praveen Krishna Veerasubramanian, Raji R Nagalla, Thuy U Luu, Esther Y Chen, Christian F Guerrero-Juarez, Kosuke Yamaga, William Pandori, Jessica Y Hsieh, Timothy L Downing, David A Fruman, Melissa B Lodoen, Maksim V Plikus, Wenqi Wang, Wendy F Liu
YAP-mediated mechanotransduction tunes the macrophage inflammatory response. Science advances 6 (49) (2020)
Jocelyn Charlton, Timothy L Downing, Zachary D Smith, Hongcang Gu, Kendell Clement, Ramona Pop, Veronika Akopian, Sven Klages, David P Santos, Alexander M Tsankov, Bernd Timmermann, Michael J Ziller, Evangelos Kiskinis, Andreas Gnirke, Alexander Meissner
Global delay in nascent strand DNA methylation. Nature structural & molecular biology 25 (4) (2018)

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Publication Activity (10 Years)

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Timothy L Downing