Wade D Van Horn

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 27

Top Topics

African American

Induced Pluripotent Stem Cells

Top Venues

Science advances

Nature communications

Temperature (Austin, Tex.)

The Journal of biological chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Dustin D Luu, Nikhil Ramesh, I Can Kazan, Karan H Shah, Gourab Lahiri, Miyeko D Mana, Sefika Banu Ozkan, Wade D Van Horn
Evidence that the cold- and menthol-sensing functions of the human TRPM8 channel evolved separately. Science advances 10 (25) (2024)
Emily G Saccuzzo, Mubark D Mebrat, Hailee F Scelsi, Minjoo Kim, Minh Thu Ma, Xinya Su, Shannon E Hill, Elisa Rheaume, Renhao Li, Matthew P Torres, James C Gumbart, Wade D Van Horn, Raquel L Lieberman
Competition between inside-out unfolding and pathogenic aggregation in an amyloid-forming β-propeller. Nature communications 15 (1) (2024)
Emily G Saccuzzo, Mubark D Mebrat, Hailee F Scelsi, Minjoo Kim, Minh Thu Ma, Xinya Su, Shannon E Hill, Elisa Rheaume, Renhao Li, Matthew P Torres, James C Gumbart, Wade D Van Horn, Raquel L Lieberman
Competition between inside-out unfolding and pathogenic aggregation in an amyloid-forming β-propeller. Nature communications 15 (1) (2024)
Emily G Saccuzzo, Mubark D Mebrat, Hailee F Scelsi, Minjoo Kim, Minh Thu Ma, Xinya Su, Shannon E Hill, Elisa Rheaume, Renhao Li, Matthew P Torres, James C Gumbart, Wade D Van Horn, Raquel L Lieberman
Competition between inside-out unfolding and pathogenic aggregation in an amyloid-forming β-propeller. Nature communications 15 (1) (2024)
Dustin D Luu, Nikhil Ramesh, I Can Kazan, Karan H Shah, Gourab Lahiri, Miyeko D Mana, Sefika Banu Ozkan, Wade D Van Horn
Evidence that the cold- and menthol-sensing functions of the human TRPM8 channel evolved separately. Science advances 10 (25) (2024)
Emily G Saccuzzo, Mubark D Mebrat, Hailee F Scelsi, Minjoo Kim, Minh Thu Ma, Xinya Su, Shannon E Hill, Elisa Rheaume, Renhao Li, Matthew P Torres, James C Gumbart, Wade D Van Horn, Raquel L Lieberman
Competition between inside-out unfolding and pathogenic aggregation in an amyloid-forming β-propeller. Nature communications 15 (1) (2024)
Emily G Saccuzzo, Mubark D Mebrat, Hailee F Scelsi, Minjoo Kim, Minh Thu Ma, Xinya Su, Shannon E Hill, Elisa Rheaume, Renhao Li, Matthew P Torres, James C Gumbart, Wade D Van Horn, Raquel L Lieberman
Competition between inside-out unfolding and pathogenic aggregation in an amyloid-forming β-propeller. Nature communications 15 (1) (2024)
Dustin D Luu, Nikhil Ramesh, I Can Kazan, Karan H Shah, Gourab Lahiri, Miyeko D Mana, Sefika Banu Ozkan, Wade D Van Horn
Evidence that the cold- and menthol-sensing functions of the human TRPM8 channel evolved separately. Science advances 10 (25) (2024)
Emily G Saccuzzo, Mubark D Mebrat, Hailee F Scelsi, Minjoo Kim, Minh Thu Ma, Xinya Su, Shannon E Hill, Elisa Rheaume, Renhao Li, Matthew P Torres, James C Gumbart, Wade D Van Horn, Raquel L Lieberman
Competition between inside-out unfolding and pathogenic aggregation in an amyloid-forming β-propeller. Nature communications 15 (1) (2024)
Dustin D Luu, Nikhil Ramesh, I Can Kazan, Karan H Shah, Gourab Lahiri, Miyeko D Mana, Sefika Banu Ozkan, Wade D Van Horn
Evidence that the cold- and menthol-sensing functions of the human TRPM8 channel evolved separately. Science advances 10 (25) (2024)
Jaimeson Veldhuizen, Helen F Mann, Nina Karamanova, Wade D Van Horn, Raymond Q Migrino, David Brafman, Mehdi Nikkhah
Modeling long QT syndrome type 2 on-a-chip via in-depth assessment of isogenic gene-edited 3D cardiac tissues. Science advances 8 (50) (2022)
Jaimeson Veldhuizen, Helen F Mann, Nina Karamanova, Wade D Van Horn, Raymond Q Migrino, David Brafman, Mehdi Nikkhah
Modeling long QT syndrome type 2 on-a-chip via in-depth assessment of isogenic gene-edited 3D cardiac tissues. Science advances 8 (50) (2022)
Jaimeson Veldhuizen, Helen F Mann, Nina Karamanova, Wade D Van Horn, Raymond Q Migrino, David Brafman, Mehdi Nikkhah
Modeling long QT syndrome type 2 on-a-chip via in-depth assessment of isogenic gene-edited 3D cardiac tissues. Science advances 8 (50) (2022)
Jaimeson Veldhuizen, Helen F Mann, Nina Karamanova, Wade D Van Horn, Raymond Q Migrino, David Brafman, Mehdi Nikkhah
Modeling long QT syndrome type 2 on-a-chip via in-depth assessment of isogenic gene-edited 3D cardiac tissues. Science advances 8 (50) (2022)
Jaimeson Veldhuizen, Helen F Mann, Nina Karamanova, Wade D Van Horn, Raymond Q Migrino, David Brafman, Mehdi Nikkhah
Modeling long QT syndrome type 2 on-a-chip via in-depth assessment of isogenic gene-edited 3D cardiac tissues. Science advances 8 (50) (2022)
Jaimeson Veldhuizen, Helen F Mann, Nina Karamanova, Wade D Van Horn, Raymond Q Migrino, David Brafman, Mehdi Nikkhah
Modeling long QT syndrome type 2 on-a-chip via in-depth assessment of isogenic gene-edited 3D cardiac tissues. Science advances 8 (50) (2022)
Dustin D Luu, Aerial M Owens, Mubark D Mebrat, Wade D Van Horn
A molecular perspective on identifying TRPV1 thermosensitive regions and disentangling polymodal activation. Temperature (Austin, Tex.) 10 (1) (2021)
V Blair Journigan, David Alarcón-Alarcón, Zhiwei Feng, Yuanqiang Wang, Tianjian Liang, Denise C Dawley, A R M Ruhul Amin, Camila Montano, Wade D Van Horn, Xiang-Qun Xie, Antonio Ferrer-Montiel, Asia Fernández-Carvajal
Structural and in Vitro Functional Characterization of a Menthyl TRPM8 Antagonist Indicates Species-Dependent Regulation. ACS medicinal chemistry letters 12 (5) (2021)
Tushar Modi, Valeria A Risso, Sergio Martinez-Rodriguez, José Antonio Gavira, Mubark D Mebrat, Wade D Van Horn, Jose M Sanchez-Ruiz, Sefika Banu Ozkan
Hinge-shift mechanism as a protein design principle for the evolution of β-lactamases from substrate promiscuity to specificity. Nature communications 12 (1) (2021)
Dustin D Luu, Aerial M Owens, Mubark D Mebrat, Wade D Van Horn
A molecular perspective on identifying TRPV1 thermosensitive regions and disentangling polymodal activation. Temperature (Austin, Tex.) 10 (1) (2021)
James M Hutchison, Ricardo Capone, Dustin D Luu, Arina Hadziselimovic, Wade D Van Horn, Charles R Sanders
Delivery of recombinant SARS-CoV-2 envelope protein into human cells. bioRxiv : the preprint server for biology (2021)
V Blair Journigan, Zhiwei Feng, Saifur Rahman, Yuanqiang Wang, A R M Ruhul Amin, Colleen E Heffner, Nicholas Bachtel, Siyi Wang, Sara Gonzalez-Rodriguez, Asia Fernández-Carvajal, Gregorio Fernández-Ballester, Jacob K Hilton, Wade D Van Horn, Antonio Ferrer-Montiel, Xiang-Qun Xie, Taufiq Rahman
Structure-Based Design of Novel Biphenyl Amide Antagonists of Human Transient Receptor Potential Cation Channel Subfamily M Member 8 Channels with Potential Implications in the Treatment of Sensory Neuropathies. ACS chemical neuroscience 11 (3) (2020)
Minjoo Kim, Nicholas J Sisco, Jacob K Hilton, Camila M Montano, Manuel A Castro, Brian R Cherry, Marcia Levitus, Wade D Van Horn
Evidence that the TRPV1 S1-S4 membrane domain contributes to thermosensing. Nature communications 11 (1) (2020)
Nicholas J Sisco, Dustin D Luu, Minjoo Kim, Wade D Van Horn
PIRT the TRP Channel Regulating Protein Binds Calmodulin and Cholesterol-Like Ligands. Biomolecules 10 (3) (2020)
Nicholas J Sisco, Cole V M Helsell, Wade D Van Horn
Competitive Interactions between PIRT, the Cold Sensing Ion Channel TRPM8, and PIP2 Suggest a Mechanism for Regulation. Scientific reports 9 (1) (2019)
Jacob K Hilton, Minjoo Kim, Wade D Van Horn
Structural and Evolutionary Insights Point to Allosteric Regulation of TRP Ion Channels. Accounts of chemical research 52 (6) (2019)
Jacob K Hilton, Taraneh Salehpour, Nicholas J Sisco, Parthasarathi Rath, Wade D Van Horn
Phosphoinositide-interacting regulator of TRP (PIRT) has opposing effects on human and mouse TRPM8 ion channels. The Journal of biological chemistry 293 (24) (2018)