William C Mobley (Mobley William)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 9

Top Topics

Epithelial Mesenchymal Transition

Cognitive Decline

Top Venues

Annals of neurology

The Journal of neuroscience : the official journal of the Society for Neuroscience

Molecular brain

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Xu-Qiao Chen, Ann Becker, Ricardo Albay, Phuong D Nguyen, Dmitry Karachentsev, Amanda J Roberts, Kevin D Rynearson, Rudolph E Tanzi, William C Mobley
γ-Secretase Modulator BPN15606 Reduced Aβ42 and Aβ40 and Countered Alzheimer-Related Pathologies in a Mouse Model of Down Syndrome. Annals of neurology (2024)
Xu-Qiao Chen, Ann Becker, Ricardo Albay, Phuong D Nguyen, Dmitry Karachentsev, Amanda J Roberts, Kevin D Rynearson, Rudolph E Tanzi, William C Mobley
γ-Secretase Modulator BPN15606 Reduced Aβ42 and Aβ40 and Countered Alzheimer-Related Pathologies in a Mouse Model of Down Syndrome. Annals of neurology 96 (2) (2024)
Xu-Qiao Chen, Ann Becker, Ricardo Albay, Phuong D Nguyen, Dmitry Karachentsev, Amanda J Roberts, Kevin D Rynearson, Rudolph E Tanzi, William C Mobley
γ-Secretase Modulator BPN15606 Reduced Aβ42 and Aβ40 and Countered Alzheimer-Related Pathologies in a Mouse Model of Down Syndrome. Annals of neurology (2024)
Xu-Qiao Chen, Ann Becker, Ricardo Albay, Phuong D Nguyen, Dmitry Karachentsev, Amanda J Roberts, Kevin D Rynearson, Rudolph E Tanzi, William C Mobley
γ-Secretase Modulator BPN15606 Reduced Aβ42 and Aβ40 and Countered Alzheimer-Related Pathologies in a Mouse Model of Down Syndrome. Annals of neurology 96 (2) (2024)
Xu-Qiao Chen, Ann Becker, Ricardo Albay, Phuong D Nguyen, Dmitry Karachentsev, Amanda J Roberts, Kevin D Rynearson, Rudolph E Tanzi, William C Mobley
γ-Secretase Modulator BPN15606 Reduced Aβ42 and Aβ40 and Countered Alzheimer-Related Pathologies in a Mouse Model of Down Syndrome. Annals of neurology 96 (2) (2024)
Xu-Qiao Chen, Mariko Sawa, Ann Becker, Dmitry Karachentsev, Xinxin Zuo, Kevin D Rynearson, Rudolph E Tanzi, William C Mobley
Retromer proteins reduced in Down syndrome and the Dp16 model: impact of APP dose and preclinical studies of a γ-secretase modulator. Annals of neurology (2023)
Zoltowska Katarzyna Marta, Das Utpal, Lismont Sam, Enzlein Thomas, Maesako Masato, Mei Cq Houser, Franco María Luisa, Gomes Moreira Diana, Karachentsev Dmitry, Becker Ann, Carsten Hopf, Marçal Vilar, Berezovska Oksana, William C Mobley, Chávez-Gutiérrez Lucía
Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling. bioRxiv : the preprint server for biology (2023)
Phoebe Valdes, Kenneth W Henry, Michael Q Fitzgerald, Koushik Muralidharan, Andrew B Caldwell, Srinivasan Ramachandran, Lawrence S B Goldstein, William C Mobley, Douglas R Galasko, Shankar Subramaniam
Limitations of the human iPSC-derived neuron model for early-onset Alzheimer's disease. Molecular brain 16 (1) (2023)
Kijung Sung, Luiz F Ferrari, Wanlin Yang, ChiHye Chung, Xiaobei Zhao, Yingli Gu, Suzhen Lin, Kai Zhang, Bianxiao Cui, Matthew L Pearn, Michael T Maloney, William C Mobley, Jon D Levine, Chengbiao Wu
Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTR in Nociception. The Journal of neuroscience : the official journal of the Society for Neuroscience 38 (14) (2018)