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Xi Chen

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 47

Top Venues

The Journal of organic chemistry

Glycobiology

Molecules (Basel, Switzerland)

ACS chemical biology

University of California Davis

Wayne State University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of California Davis Jul 1o 2011

United States

Professor :: Department of Chemistry

Education History

Wayne State University Sep 1o 1997 - Jun 30o 2000

United States

PHD :: Department of Chemistry

Publications

Amanda L Lewis, Philip V Toukach, Evan Bolton, Xi Chen, Martin Frank, Thomas Lütteke, Yuriy Knirel, Ian Schoenhofen, Ajit Varki, Evgeny Vinogradov, Robert J Woods, Natasha Zachara, Jian Zhang, Johannis P Kamerling, Sriram Neelamegham, null null
Cataloging natural sialic acids and other nonulosonic acids (NulOs), and their representation using the Symbol Nomenclature for Glycans. Glycobiology (2023)
Amanda L Lewis, Philip V Toukach, Evan Bolton, Xi Chen, Martin Frank, Thomas Lütteke, Yuriy Knirel, Ian Schoenhofen, Ajit Varki, Evgeny Vinogradov, Robert J Woods, Natasha Zachara, Jian Zhang, Johannis P Kamerling, Sriram Neelamegham, null null
Cataloging natural sialic acids and other nonulosonic acids (NulOs), and their representation using the Symbol Nomenclature for Glycans. Glycobiology 33 (2) (2023)
Libo Zhang, Yanhong Li, Riyao Li, Xiaohong Yang, Zimin Zheng, Jingxin Fu, Hai Yu, Xi Chen
Glycoprotein In Vitro N-Glycan Processing Using Enzymes Expressed in E. coli . Molecules (Basel, Switzerland) 28 (6) (2023)
Hai Yu, Libo Zhang, Xiaohong Yang, Yuanyuan Bai, Xi Chen
Process Engineering and Glycosyltransferase Improvement for Short Route Chemoenzymatic Total Synthesis of GM1 Gangliosides. Chemistry (Weinheim an der Bergstrasse, Germany) (2023)
Amanda L Lewis, Philip V Toukach, Evan Bolton, Xi Chen, Martin Frank, Thomas Lütteke, Yuriy Knirel, Ian Schoenhofen, Ajit Varki, Evgeny Vinogradov, Robert J Woods, Natasha Zachara, Jian Zhang, Johannis P Kamerling, Sriram Neelamegham, null null
Cataloging natural sialic acids and other nonulosonic acids (NulOs), and their representation using the Symbol Nomenclature for Glycans. Glycobiology (2023)
Libo Zhang, Yanhong Li, Riyao Li, Xiaohong Yang, Zimin Zheng, Jingxin Fu, Hai Yu, Xi Chen
Glycoprotein In Vitro N-Glycan Processing Using Enzymes Expressed in E. coli . Molecules (Basel, Switzerland) 28 (6) (2023)
Amanda L Lewis, Philip V Toukach, Evan Bolton, Xi Chen, Martin Frank, Thomas Lütteke, Yuriy Knirel, Ian Schoenhofen, Ajit Varki, Evgeny Vinogradov, Robert J Woods, Natasha Zachara, Jian Zhang, Johannis P Kamerling, Sriram Neelamegham, null null
Cataloging natural sialic acids and other nonulosonic acids (NulOs), and their representation using the Symbol Nomenclature for Glycans. Glycobiology 33 (2) (2023)
Amanda L Lewis, Philip V Toukach, Evan Bolton, Xi Chen, Martin Frank, Thomas Lütteke, Yuriy Knirel, Ian Schoenhofen, Ajit Varki, Evgeny Vinogradov, Robert J Woods, Natasha Zachara, Jian Zhang, Johannis P Kamerling, Sriram Neelamegham, null null
Cataloging natural sialic acids and other nonulosonic acids (NulOs), and their representation using the Symbol Nomenclature for Glycans. Glycobiology 33 (2) (2023)
Libo Zhang, Yanhong Li, Riyao Li, Xiaohong Yang, Zimin Zheng, Jingxin Fu, Hai Yu, Xi Chen
Glycoprotein In Vitro N-Glycan Processing Using Enzymes Expressed in E. coli . Molecules (Basel, Switzerland) 28 (6) (2023)
Thomas Senage, Anu Paul, Thierry Le Tourneau, Imen Fellah-Hebia, Marta Vadori, Salam Bashir, Manuel Galiñanes, Tomaso Bottio Jean Christian Roussel, Gino Gerosa, Arturo Evangelista, Luigi P Badano, Alberto Nassi, Cristina Costa, Cesare Galli, Rizwan A Manji, Caroline Cueff de Monchy, Nicolas Piriou, Romain Capoulade, Jean-Michel Serfaty, Guillaume Guimbretière, Etienne Dantan, Alejandro Ruiz-Majoral, Guénola Coste du Fou, Shani Leviatan Ben-Arye, Liana Govani, Sharon Yehuda, Shirley Bachar Abramovitch, Ron Amon, Eliran Moshe Reuven, Yafit Atiya-Nasagi, Hai Yu, Laura Iop, Kelly Casós, Sebastián G Kuguel, Arnau Blasco-Lucas, Eduard Permanyer, Fabrizio Sbraga, Roger Llatjós, Gabriel Moreno-Gonzalez, Melchor Sanchez-Martinez, Michael E Breimer, Jan Holgersson, Susann Teneberg, Marta Pascual-Gilabert, Alfons Nonell-Canals, Yasuhiro Takeuchi, Xi Chen, Rafael Mañez, Jean Christian Roussel, Jean-Paul Soulillou, Emanuele Cozzi, Vered Padler-Karavani
The role of antibody responses against glycans in bioprosthetic heart valve calcification and deterioration. Nature medicine 28 (2) (2022)
Yuanyuan Bai, Xiaohong Yang, Hai Yu, Xi Chen
Substrate and Process Engineering for Biocatalytic Synthesis and Facile Purification of Human Milk Oligosaccharides. ChemSusChem 15 (9) (2022)
Anoopjit Singh Kooner, Yue Yuan, Hai Yu, Hyeog Kang, Laura Klenow, Robert Daniels, Xi Chen
Sialosides Containing 7- N -Acetyl Sialic Acid Are Selective Substrates for Neuraminidases from Influenza A Viruses. ACS infectious diseases (2022)
Lisa Oh, Ajit Varki, Xi Chen, Lee-Ping Wang
SARS-CoV-2 and MERS-CoV Spike Protein Binding Studies Support Stable Mimic of Bound 9- O -Acetylated Sialic Acids. Molecules (Basel, Switzerland) 27 (16) (2022)
Lisa Oh, Yang Ji, Wanqing Li, Ajit Varki, Xi Chen, Lee-Ping Wang
O -Acetyl Migration within the Sialic Acid Side Chain: A Mechanistic Study Using the Ab Initio Nanoreactor. Biochemistry 61 (18) (2022)
Xuefeng Cao, Shuaishuai Wang, Madhusudhan Reddy Gadi, Ding Liu, Peng G Wang, Xiu-Feng Wan, Jian Zhang, Xi Chen, Lauren E Pepi, Parastoo Azadi, Lei Li
Systematic synthesis of bisected N -glycans and unique recognitions by glycan-binding proteins. Chemical science 13 (25) (2022)
Xiaohong Yang, Xiaoxiao Yang, Hai Yu, Lan Na, Tamashree Ghosh, John B McArthur, Tsui-Fen Chou, Patricia Dickson, Xi Chen
A GH89 human α-N-acetylglucosaminidase (hNAGLU) homologue from gut microbe Bacteroides thetaiotaomicron capable of hydrolyzing heparosan oligosaccharides. AMB Express 11 (1) (2021)
Shoib S Siddiqui, Chirag Dhar, Venkatasubramaniam Sundaramurthy, Aniruddha Sasmal, Hai Yu, Esther Bandala-Sanchez, Miaomiao Li, Xiaoxiao Zhang, Xi Chen, Leonard C Harrison, Ding Xu, Ajit Varki
Sialoglycan recognition is a common connection linking acidosis, zinc, and HMGB1 in sepsis. Proceedings of the National Academy of Sciences of the United States of America 118 (10) (2021)
Shuaishuai Wang, Congcong Chen, Madhusudhan Reddy Gadi, Varma Saikam, Ding Liu, He Zhu, Roni J Bollag, Zhuoqi Liu, Xi Chen, Fengshan Wang, Peng George Wang, Peixue Ling, Wanyi Guan, Lei Li
Chemoenzymatic modular assembly of O-GalNAc glycans for functional glycomics. Nature communications 12 (1) (2021)
Sudeshna Saha, Alison Coady, Aniruddha Sasmal, Kunio Kawanishi, Biswa Choudhury, Hai Yu, Ricardo U Sorensen, Jaime Inostroza, Ian C Schoenhofen, Xi Chen, Anja Münster-Kühnel, Chihiro Sato, Ken Kitajima, Sanjay Ram, Victor Nizet, Ajit Varki
Exploring the Impact of Ketodeoxynonulosonic Acid in Host-Pathogen Interactions Using Uptake and Surface Display by Nontypeable Haemophilus influenzae. mBio 12 (1) (2021)
Libo Zhang, Hai Yu, Yuanyuan Bai, Bijoyananda Mishra, Xiaoxiao Yang, Jing Wang, Evan B Yu, Riyao Li, Xi Chen
A Neoglycoprotein-Immobilized Fluorescent Magnetic Bead Suspension Multiplex Array for Galectin-Binding Studies. Molecules (Basel, Switzerland) 26 (20) (2021)
Anoopjit Singh Kooner, Sandra Diaz, Hai Yu, Abhishek Santra, Ajit Varki, Xi Chen
Chemoenzymatic Synthesis of Sialosides Containing 7-N- or 7,9-Di-N-acetyl Sialic Acid as Stable O-Acetyl Analogues for Probing Sialic Acid-Binding Proteins. The Journal of organic chemistry 86 (21) (2021)
Hai Yu, Madhusudhan Reddy Gadi, Yuanyuan Bai, Libo Zhang, Lei Li, Jun Yin, Peng George Wang, Xi Chen
Chemoenzymatic Total Synthesis of GM3 Gangliosides Containing Different Sialic Acid Forms and Various Fatty Acyl Chains. The Journal of organic chemistry 86 (13) (2021)
Yang Ji, Aniruddha Sasmal, Wanqing Li, Lisa Oh, Saurabh Srivastava, Audra A Hargett, Brian R Wasik, Hai Yu, Sandra Diaz, Biswa Choudhury, Colin R Parrish, Darόn I Freedberg, Lee-Ping Wang, Ajit Varki, Xi Chen
Reversible O-Acetyl Migration within the Sialic Acid Side Chain and Its Influence on Protein Recognition. ACS chemical biology 16 (10) (2021)
John B McArthur, Abhishek Santra, Wanqing Li, Anoopjit S Kooner, Ziqi Liu, Hai Yu, Xi Chen
L. pneumophila CMP-5,7-di-N-acetyllegionaminic acid synthetase (LpCLS)-involved chemoenzymatic synthesis of sialosides and analogues. Organic & biomolecular chemistry 18 (4) (2020)
Tri Nguyen, Sohyoung Lee, Yi-An Yang, Changhwan Ahn, Ji Hyun Sim, Tiffany G Kei, Karen N Barnard, Hai Yu, Shawn K Millano, Xi Chen, Colin R Parrish, Jeongmin Song
The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication. PLoS pathogens 16 (2) (2020)
Riyao Li, Anoopjit S Kooner, Saddam M Muthana, Yue Yuan, Hai Yu, Xi Chen
A Chemoenzymatic Synthon Strategy for Synthesizing N-Acetyl Analogues of O-Acetylated N. meningitidis W Capsular Polysaccharide Oligosaccharides. The Journal of organic chemistry 85 (24) (2020)
Lan Na, Hai Yu, John B McArthur, Tamashree Ghosh, Thomas Asbell, Xi Chen
Engineer P. multocida Heparosan Synthase 2 (PmHS2) for Size-Controlled Synthesis of Longer Heparosan Oligosaccharides. ACS catalysis 10 (11) (2020)
Ron Amon, Ronit Rosenfeld, Shahar Perlmutter, Oliver C Grant, Sharon Yehuda, Aliza Borenstein-Katz, Ron Alcalay, Tal Marshanski, Hai Yu, Ron Diskin, Robert J Woods, Xi Chen, Vered Padler-Karavani
Directed Evolution of Therapeutic Antibodies Targeting Glycosylation in Cancer. Cancers 12 (10) (2020)
Nicholas K Hurlburt, Jasper Guan, Hoonsan Ong, Hai Yu, Xi Chen, Andrew J Fisher
Structural characterization of a nonhydrolyzing UDP-GlcNAc 2-epimerase from Neisseria meningitidis serogroup A. Acta crystallographica. Section F, Structural biology communications 76 (Pt 11) (2020)
Riyao Li, Hai Yu, Saddam M Muthana, Darόn I Freedberg, Xi Chen
Size-Controlled Chemoenzymatic Synthesis of Homogeneous Oligosaccharides of Neisseria meningitidis W Capsular Polysaccharide. ACS catalysis 10 (4) (2020)
Tian Gao, Jingyu Yan, Chang-Cheng Liu, Angelina S Palma, Zhimou Guo, Min Xiao, Xi Chen, Xin-Miao Liang, Wengang Chai, Hongzhi Cao
Chemoenzymatic Synthesis of O-Mannose Glycans Containing Sulfated or Nonsulfated HNK-1 Epitope. Journal of the American Chemical Society 141 (49) (2019)
Philip K Yuen, Sydnee A Green, Jonathan Ashby, Kori T Lay, Abhishek Santra, Xi Chen, Martin P Horvath, Sheila S David
Targeting Base Excision Repair Glycosylases with DNA Containing Transition State Mimics Prepared via Click Chemistry. ACS chemical biology 14 (1) (2019)
John B McArthur, Hai Yu, Xi Chen
A Bacterial β1-3-Galactosyltransferase Enables Multigram-Scale Synthesis of Human Milk Lacto-N-tetraose (LNT) and Its Fucosides. ACS catalysis 9 (12) (2019)
Melissa M Matthews, John B McArthur, Yanhong Li, Hai Yu, Xi Chen, Andrew J Fisher
Catalytic Cycle of Neisseria meningitidis CMP-Sialic Acid Synthetase Illustrated by High-Resolution Protein Crystallography. Biochemistry 59 (34) (2019)
Eliran Moshe Reuven, Shani Leviatan Ben-Arye, Hai Yu, Roberto Duchi, Andrea Perota, Sophie Conchon, Shirley Bachar Abramovitch, Jean-Paul Soulillou, Cesare Galli, Xi Chen, Vered Padler-Karavani
Biomimetic Glyconanoparticle Vaccine for Cancer Immunotherapy. ACS nano 13 (3) (2019)
Yanhong Li, Riyao Li, Hai Yu, Xue Sheng, Jing Wang, Andrew J Fisher, Xi Chen
Enterococcus faecalis α1-2-mannosidase (EfMan-I): an efficient catalyst for glycoprotein N-glycan modification. FEBS letters 594 (3) (2019)
Shani Leviatan Ben-Arye, Christoph Schneider, Hai Yu, Salam Bashir, Xi Chen, Stephan von Gunten, Vered Padler-Karavani
Differential Recognition of Diet-Derived Neu5Gc-Neoantigens on Glycan Microarrays by Carbohydrate-Specific Pooled Human IgG and IgA Antibodies. Bioconjugate chemistry 30 (5) (2019)
Wanqing Li, Abhishek Santra, Hai Yu, Teri J Slack, Musleh M Muthana, Dashuang Shi, Yang Liu, Xi Chen
9-Azido-9-deoxy-2,3-difluorosialic Acid as a Subnanomolar Inhibitor against Bacterial Sialidases. The Journal of organic chemistry 84 (11) (2019)
Abhishek Santra, An Xiao, Hai Yu, Wanqing Li, Yanhong Li, Linh Ngo, John B McArthur, Xi Chen
A Diazido Mannose Analogue as a Chemoenzymatic Synthon for Synthesizing Di-N-acetyllegionaminic Acid-Containing Glycosides. Angewandte Chemie (International ed. in English) 57 (11) (2018)
An Xiao, Teri J Slack, Yanhong Li, Dashuang Shi, Hai Yu, Wanqing Li, Yang Liu, Xi Chen
Streptococcus pneumoniae Sialidase SpNanB-Catalyzed One-Pot Multienzyme (OPME) Synthesis of 2,7-Anhydro-Sialic Acids as Selective Sialidase Inhibitors. The Journal of organic chemistry 83 (18) (2018)
Xuan Fu, Wenjing Shang, Shuaishuai Wang, Yunpeng Liu, Jingyao Qu, Xi Chen, Peng George Wang, Junqiang Fang
A general strategy for the synthesis of homogeneous hyaluronan conjugates and their biological applications. Chemical communications (Cambridge, England) 53 (25) (2018)
John B McArthur, Hai Yu, Nova Tasnima, Christie M Lee, Andrew J Fisher, Xi Chen
α2-6-Neosialidase: A Sialyltransferase Mutant as a Sialyl Linkage-Specific Sialidase. ACS chemical biology 13 (5) (2018)
Abhishek Santra, Yanhong Li, Tamashree Ghosh, Riyao Li, Hai Yu, Xi Chen
Regioselective One-Pot Multienzyme (OPME) Chemoenzymatic Strategies for Systematic Synthesis of Sialyl Core 2 Glycans. ACS catalysis 9 (1) (2018)
Salam Bashir, Shani Leviatan Ben Arye, Eliran Moshe Reuven, Hai Yu, Cristina Costa, Manuel Galiñanes, Tomaso Bottio, Xi Chen, Vered Padler-Karavani
Presentation Mode of Glycans Affect Recognition of Human Serum anti-Neu5Gc IgG Antibodies. Bioconjugate chemistry 30 (1) (2018)
Annie N Samraj, Kimberly A Bertrand, Robert Luben, Zahra Khedri, Hai Yu, Dzung Nguyen, Christopher J Gregg, Sandra L Diaz, Sherilyn Sawyer, Xi Chen, A Heather Eliassen, Vered Padler-Karavani, Kana Wu, Kay-Tee Khaw, Walter Willett, Ajit Varki
Polyclonal human antibodies against glycans bearing red meat-derived non-human sialic acid N-glycolylneuraminic acid are stable, reproducible, complex and vary between individuals: Total antibody levels are associated with colorectal cancer risk. PloS one 13 (6) (2018)
Hai Yu, Xuebin Yan, Chloe A Autran, Yanhong Li, Sabrina Etzold, Joanna Latasiewicz, Bianca M Robertson, Jiaming Li, Lars Bode, Xi Chen
Enzymatic and Chemoenzymatic Syntheses of Disialyl Glycans and Their Necrotizing Enterocolitis Preventing Effects. The Journal of organic chemistry 82 (24) (2017)
Zahra Khedri, An Xiao, Hai Yu, Corinna Susanne Landig, Wanqing Li, Sandra Diaz, Brian R Wasik, Colin R Parrish, Lee-Ping Wang, Ajit Varki, Xi Chen
A Chemical Biology Solution to Problems with Studying Biologically Important but Unstable 9-O-Acetyl Sialic Acids. ACS chemical biology 12 (1) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Xi Chen