Xiaochun Li

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 25

Top Venues

Nature communications

Science advances

Nature

Nature cardiovascular research

University of Texas Southwestern Medical Center

Tsinghua University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Texas Southwestern Medical Center Jun 01 2017

United States

Assistant Professor :: Molecular Genetics

Rockefeller University Aug 01 2012 - May 31 2017

United States

Postdoctor :: Laboratory of Cell Biology

Education History

Tsinghua University Jul 01 2008 - Jan 31 2012

China

PHD :: Biology

Tsinghua University Aug 01 2004 - Jun 30 2008

China

BSC :: Chemistry

Publications

Philip Schmiege, Linda Donnelly, Nadia Elghobashi-Meinhardt, Chia-Hsueh Lee, Xiaochun Li
Structure and inhibition of the human lysosomal transporter Sialin. Nature communications 15 (1) (2024)
Philip Schmiege, Linda Donnelly, Nadia Elghobashi-Meinhardt, Chia-Hsueh Lee, Xiaochun Li
Structure and inhibition of the human lysosomal transporter Sialin. Nature communications 15 (1) (2024)
Philip Schmiege, Linda Donnelly, Nadia Elghobashi-Meinhardt, Chia-Hsueh Lee, Xiaochun Li
Structure and inhibition of the human lysosomal transporter Sialin. Nature communications 15 (1) (2024)
Philip Schmiege, Linda Donnelly, Nadia Elghobashi-Meinhardt, Chia-Hsueh Lee, Xiaochun Li
Structure and inhibition of the human lysosomal transporter Sialin. Nature communications 15 (1) (2024)
Tao Long, Yichi Zhang, Linda Donnelly, Hui Li, Yu-Chung Pien, Ning Liu, Eric N Olson, Xiaochun Li
Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion. Nature structural & molecular biology (2023)
Hongwen Chen, Yu Qin, Marissa Chou, Jason G Cyster, Xiaochun Li
Transmembrane protein CD69 acts as an S1PR1 agonist. eLife 12 (2023)
Hongwen Chen, Kevin Y Chen, Weijiao Huang, Louis M Staudt, Jason G Cyster, Xiaochun Li
Structure of S1PR2-heterotrimeric G 13 signaling complex. Science advances 8 (13) (2022)
Yingyuan Sun, Xiaochun Li
Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states. Nature cardiovascular research 1 (3) (2022)
Yang Liu, Xiaofeng Qi, Linda Donnelly, Nadia Elghobashi-Meinhardt, Tao Long, Rich W Zhou, Yingyuan Sun, Boyuan Wang, Xiaochun Li
Mechanisms and inhibition of Porcupine-mediated Wnt acylation. Nature 607 (7920) (2022)
Rong Wang, Yu Qin, Xiao-Song Xie, Xiaochun Li
Molecular basis of mEAK7-mediated human V-ATPase regulation. Nature communications 13 (1) (2022)
Yingyuan Sun, Xiaochun Li
Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states. Nature cardiovascular research 1 (3) (2022)
Hongwen Chen, Xiaofeng Qi, Rebecca A Faulkner, Marc M Schumacher, Linda M Donnelly, Russell A DeBose-Boyd, Xiaochun Li
Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain. Nature communications 13 (1) (2022)
Tao Long, Yang Liu, Yu Qin, Russell A DeBose-Boyd, Xiaochun Li
Structures of dimeric human NPC1L1 provide insight into mechanisms for cholesterol absorption. Science advances 7 (34) (2021)
Yingyuan Sun, Jin Wang, Tao Long, Xiaofeng Qi, Linda Donnelly, Nadia Elghobashi-Meinhardt, Leticia Esparza, Jonathan C Cohen, Xiao-Song Xie, Helen H Hobbs, Xiaochun Li
Molecular basis of cholesterol efflux via ABCG subfamily transporters. Proceedings of the National Academy of Sciences of the United States of America 118 (34) (2021)
Rong Wang, Yu Qin, Xiaochun Li
Structural basis of acyl-CoA transport across the peroxisomal membrane by human ABCD1. Cell research (2021)
Rong Wang, Jin Wang, Abdirahman Hassan, Chia-Hsueh Lee, Xiao-Song Xie, Xiaochun Li
Molecular basis of V-ATPase inhibition by bafilomycin A1. Nature communications 12 (1) (2021)
Hongwen Chen, Yang Liu, Xiaochun Li
Structure of human Dispatched-1 provides insights into Hedgehog ligand biogenesis. Life science alliance 3 (8) (2020)
Xiaofeng Qi, Lucas Friedberg, Ryan De Bose-Boyd, Tao Long, Xiaochun Li
Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling. Nature chemical biology 16 (12) (2020)
Tao Long, Xiaofeng Qi, Abdirahman Hassan, Qiren Liang, Jef K De Brabander, Xiaochun Li
Structural basis for itraconazole-mediated NPC1 inhibition. Nature communications 11 (1) (2020)
Rong Wang, Tao Long, Abdirahman Hassan, Jin Wang, Yingyuan Sun, Xiao-Song Xie, Xiaochun Li
Cryo-EM structures of intact V-ATPase from bovine brain. Nature communications 11 (1) (2020)
Rong Wang, Xiaofeng Qi, Philip Schmiege, Elias Coutavas, Xiaochun Li
Marked structural rearrangement of mannose 6-phosphate/IGF2 receptor at different pH environments. Science advances 6 (7) (2020)
Tao Long, Yingyuan Sun, Abdirahman Hassan, Xiaofeng Qi, Xiaochun Li
Structure of nevanimibe-bound tetrameric human ACAT1. Nature 581 (7808) (2020)
Tao Long, Abdirahman Hassan, Bonne M Thompson, Jeffrey G McDonald, Jiawei Wang, Xiaochun Li
Structural basis for human sterol isomerase in cholesterol biosynthesis and multidrug recognition. Nature communications 10 (1) (2019)
Xiaofeng Qi, Philip Schmiege, Elias Coutavas, Xiaochun Li
Two Patched molecules engage distinct sites on Hedgehog yielding a signaling-competent complex. Science (New York, N.Y.) 362 (6410) (2018)
Michael Fine, Philip Schmiege, Xiaochun Li
Structural basis for PtdInsP2-mediated human TRPML1 regulation. Nature communications 9 (1) (2018)

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Publication Activity (10 Years)

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Xiaochun Li