Zhichao Zhang (Junjie Zhu)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 19

Top Topics

Chronic Myeloid Leukemia

Protein Protein

Top Venues

Journal of medicinal chemistry

Journal of molecular modeling

Analytical chemistry

Chembiochem : a European journal of chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Maojun Jiang, Hong Zhang, Yang Song, Fangkui Yin, Zhiyuan Hu, Xin Li, Yuying Wang, Zheming Wang, Yitong Li, Zihan Wang, Yanxin Zhang, Siyao Wang, Shaohua Lu, Guanghong Xu, Ting Song, Ziqian Wang, Zhichao Zhang
Discovery of Biphenyl Derivatives to Target Hsp70-Bim Protein-Protein Interaction in Chronic Myeloid Leukemia by Scaffold Hopping Strategy. Journal of medicinal chemistry 67 (14) (2024)
Maojun Jiang, Hong Zhang, Yang Song, Fangkui Yin, Zhiyuan Hu, Xin Li, Yuying Wang, Zheming Wang, Yitong Li, Zihan Wang, Yanxin Zhang, Siyao Wang, Shaohua Lu, Guanghong Xu, Ting Song, Ziqian Wang, Zhichao Zhang
Discovery of Biphenyl Derivatives to Target Hsp70-Bim Protein-Protein Interaction in Chronic Myeloid Leukemia by Scaffold Hopping Strategy. Journal of medicinal chemistry 67 (14) (2024)
Xin Li, Yuying Wang, Maojun Jiang, Fangkui Yin, Hong Zhang, Linjie Yuan, Jingjing Liu, Xingyu Wang, Ziqian Wang, Zhichao Zhang
Exploring the binding mechanism of a small molecular Hsp70-Bim PPI inhibitor through molecular dynamic simulation. Journal of molecular modeling 30 (3) (2024)
Xin Li, Yuying Wang, Maojun Jiang, Fangkui Yin, Hong Zhang, Linjie Yuan, Jingjing Liu, Xingyu Wang, Ziqian Wang, Zhichao Zhang
Exploring the binding mechanism of a small molecular Hsp70-Bim PPI inhibitor through molecular dynamic simulation. Journal of molecular modeling 30 (3) (2024)
Maojun Jiang, Hong Zhang, Yang Song, Fangkui Yin, Zhiyuan Hu, Xin Li, Yuying Wang, Zheming Wang, Yitong Li, Zihan Wang, Yanxin Zhang, Siyao Wang, Shaohua Lu, Guanghong Xu, Ting Song, Ziqian Wang, Zhichao Zhang
Discovery of Biphenyl Derivatives to Target Hsp70-Bim Protein-Protein Interaction in Chronic Myeloid Leukemia by Scaffold Hopping Strategy. Journal of medicinal chemistry 67 (14) (2024)
Maojun Jiang, Hong Zhang, Yang Song, Fangkui Yin, Zhiyuan Hu, Xin Li, Yuying Wang, Zheming Wang, Yitong Li, Zihan Wang, Yanxin Zhang, Siyao Wang, Shaohua Lu, Guanghong Xu, Ting Song, Ziqian Wang, Zhichao Zhang
Discovery of Biphenyl Derivatives to Target Hsp70-Bim Protein-Protein Interaction in Chronic Myeloid Leukemia by Scaffold Hopping Strategy. Journal of medicinal chemistry (2024)
Xin Li, Yuying Wang, Maojun Jiang, Fangkui Yin, Hong Zhang, Linjie Yuan, Jingjing Liu, Xingyu Wang, Ziqian Wang, Zhichao Zhang
Exploring the binding mechanism of a small molecular Hsp70-Bim PPI inhibitor through molecular dynamic simulation. Journal of molecular modeling 30 (3) (2024)
Ziqian Wang, Hong Zhang, Xin Li, Yang Song, Yuying Wang, Zhiyuan Hu, Qishuang Gao, Maojun Jiang, Fangkui Yin, Linjie Yuan, Jingjing Liu, Ting Song, Shaohua Lu, Guanghong Xu, Zhichao Zhang
Exploiting the "Hot-Spots" of Hsp70 - Bim Protein - Protein Interaction to Optimize the 1-Oxo-1 H -phenalene-2,3-dicarbonitrile Analogues as Specific Hsp70 - Bim Inhibitors. Journal of medicinal chemistry (2023)
Ting Song, Yafei Guo, Zuguang Xue, Zongwei Guo, Ziqian Wang, Donghai Lin, Hong Zhang, Hao Pan, Xiaodong Zhang, Fangkui Yin, Hang Wang, Laura Bonnette Uwituze, Zhichao Zhang
Small-molecule inhibitor targeting the Hsp70-Bim protein-protein interaction in CML cells overcomes BCR-ABL-independent TKI resistance. Leukemia 35 (10) (2021)
Ziqian Wang, Xiaodong Zhang, Hong Zhang, Yao Tang, Hao Pan, Hang Wang, Tong Ji, Yafei Guo, Qishuang Gao, Ting Song, Zhichao Zhang
Discovery of a Fluorogenic Probe for In Situ Pyruvate Kinase M2 Isoform (PKM2) Labeling through Chemoselective SNAr with a Binding Site Lysine Residue. Analytical chemistry 93 (28) (2021)
Yan Li, Wenjie Fan, Qineng Gong, Jie Tian, Mi Zhou, Qing Li, Laura B Uwituze, Zhichao Zhang, Ran Hong, Ren-Xiao Wang
Structure-Based Optimization of 3-Phenyl-N-(2-(3-phenylureido)ethyl)thiophene-2-sulfonamide Derivatives as Selective Mcl-1 Inhibitors. Journal of medicinal chemistry 64 (14) (2021)
Xiaodong Zhang, Ziqian Wang, Zongwei Guo, Ting Song, Nianzhe He, Junjie Zhu, Keke Cao, Zhichao Zhang
A "Three-in-One" Multifunctional Probe for Bcl-2/Mcl-1 Profiling and Visualizing in Situ. Chembiochem : a European journal of chemical biology 22 (2) (2020)
Anhui Wang, Yuebin Zhang, Huiying Chu, Chenyi Liao, Zhichao Zhang, Guo-Hui Li
Higher Accuracy Achieved for Protein-Ligand Binding Pose Prediction by Elastic Network Model-Based Ensemble Docking. Journal of chemical information and modeling 60 (6) (2020)
Ziqian Wang, Ting Song, Zongwei Guo, Keke Cao, Chao Chen, Yingang Feng, Hang Wang, Fangkui Yin, Sheng Zhou, Jian Dai, Zhichao Zhang
Targeting the Allosteric Pathway That Interconnects the Core-Functional Scaffold and the Distal Phosphorylation Sites for Specific Dephosphorylation of Bcl-2. Journal of medicinal chemistry 63 (22) (2020)
Zhichao Zhang, Ziqian Wang, Zongwei Guo, Xiaodong Zhang, Ting Song, Yafei Guo, Tong Ji, Zhichao Zhang
Structure-based design, synthesis, and evaluation of Bcl-2/Mcl-1 dual inhibitors. Archiv der Pharmazie 353 (5) (2020)
Anhui Wang, Dinglin Zhang, Yan Li, Zhichao Zhang, Guo-Hui Li
Large-Scale Biomolecular Conformational Transitions Explored by a Combined Elastic Network Model and Enhanced Sampling Molecular Dynamics. The journal of physical chemistry letters 11 (1) (2019)
Ziqian Wang, Nianzhe He, Zongwei Guo, Cuili Niu, Ting Song, Yafei Guo, Keke Cao, Anhui Wang, Junjie Zhu, Xiaodong Zhang, Zhichao Zhang
Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. Journal of medicinal chemistry 62 (17) (2019)
Jin Chen, Anhui Wang, Bing Liu, Ye Zhou, Pan Luo, Zhichao Zhang, Guo-Hui Li, Quentin Liu, Fang-Jun Wang
Quantitative Lysine Reactivity Profiling Reveals Conformational Inhibition Dynamics and Potency of Aurora A Kinase Inhibitors. Analytical chemistry 91 (20) (2019)
Ziqian Wang, Zongwei Guo, Ting Song, Xiaodong Zhang, Nianzhe He, Peng Liu, Peiran Wang, Zhichao Zhang
Proteome-Wide Identification of On- and Off-Targets of Bcl-2 Inhibitors in Native Biological Systems by Using Affinity-Based Probes (AfBPs). Chembiochem : a European journal of chemical biology 19 (21) (2018)