Login / Signup

Longitudinal changes of spinal cord grey and white matter following spinal cord injury.

Gergely DavidDario PfyfferKevin VallottonNikolai PfenderAlan ThompsonNikolaus WeiskopfSiawoosh MohammadiArmin CurtPatrick Freund
Published in: Journal of neurology, neurosurgery, and psychiatry (2021)
This study describes the spatiotemporal dynamics of tissue-specific spinal cord neurodegeneration above and below a spinal cord injury. While above the injury, grey matter atrophy lagged initially behind white matter neurodegeneration, in the lumbar enlargement these processes progressed in parallel. Tracking trajectories of tissue-specific neurodegeneration provides valuable assessment tools for monitoring recovery and treatment effects.
Keyphrases
  • white matter
  • spinal cord
  • spinal cord injury
  • neuropathic pain
  • multiple sclerosis
  • depressive symptoms
  • minimally invasive
  • cross sectional
  • replacement therapy