Evaluation of interleukin-6 and its soluble receptor components sIL-6R and sgp130 as markers of inflammation in inflammatory bowel diseases.

Susanna NikolausGeorg H WaetzigSven ButzinMonika ZiolkiewiczNatalie Al-MassadFlorian ThiemeUlf LövgrenBirgitte B RasmussenTorsten M ReinheimerDirk SeegertPhilip RosenstielSilke SzymczakStefan Schreiber

Published in: International journal of colorectal disease (2018)

Only a minority of IBD patients shows elevated IL-6 serum levels. However, in these patients, IL-6 is strongly associated with disease activity. Its soluble receptors sIL-6R and sgp130 do not appear useful as biomarkers in IBD.

Keyphrases

end stage renal disease
disease activity
ejection fraction
newly diagnosed
systemic lupus erythematosus
chronic kidney disease
rheumatoid arthritis
peritoneal dialysis
prognostic factors
patient reported outcomes
rheumatoid arthritis patients