Switching to tenofovir alafenamide for nucleos(t)ide analogue-experienced patients with chronic hepatitis B: week 144 results from a real-world, multi-centre cohort study.
Eiichi OgawaMakoto NakamutaToshimasa KoyanagiAritsune OohoNorihiro FurusyoEiji KajiwaraKazufumi DohmenAkira KawanoTakeaki SatohKazuhiro TakahashiKoichi AzumaNobuyuki YamashitaNaoki YamashitaRie SugimotoHiromasa AmagaseMasami KuniyoshiYasunori IchikiChie MoritaMasaki KatoShinji ShimodaHideyuki NomuraJun Hayashinull nullPublished in: Alimentary pharmacology & therapeutics (2022)
Switching to TAF remained effective and safe for up to 3 years. Given the increasing comorbidities related to ageing, it will be important to carefully follow the change in the lipid levels of patients with a prior TDF-based regimen.