CellKine clinical trial: first report from a phase 1 trial of allogeneic bone marrow-derived mesenchymal stem cells in subjects with painful lumbar facet joint arthropathy.

Dan YanAbba C ZubairMichael D OsborneRobert Pagan-RosadoJeffrey A StoneVance T LehmanNisha C DurandEva KubrovaZhen WangDrew M WitterMeghan M BaerGabriela C PonceAlfredo Quiñones-HinojosaWenchun Qu

Published in: Pain reports (2024)

This case report suggests the safety and feasibility of administering intra-articular allogeneic BM-MSCs, offering therapeutic benefits for pain management and functional activities.

Keyphrases

bone marrow
pain management
mesenchymal stem cells
case report
clinical trial
stem cell transplantation
chronic pain
umbilical cord
minimally invasive
hematopoietic stem cell
phase ii
high dose
open label
double blind
randomized controlled trial
low dose
phase iii