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Comparative biomarkers for HBsAg loss with antiviral therapy shows dominant influence of quantitative HBsAg (qHBsAg).

Seng Gee LimWah Wah PhyoJoanna Zhi Jie LingGavin ClohertyEmily K ButlerMary C KuhnsAnne L McNamaraVera HolzmayerJeffrey GerschWei Lyn YangJing Hieng NguJason ChangJessica TanTaufique AhmedYock Young DanYin Mei LeeGuan Huei LeePoh Seng TanDaniel Q HuangHtet Toe Wai KhineChris LeeAmy TayEdwin Chan
Published in: Alimentary pharmacology & therapeutics (2020)
On-treatment biomarker predictors were better than baseline ones, and the best predictor of HBsAg loss at 72 weeks was week 8 qHBsAg <70 IU/mL.
Keyphrases
  • hepatitis b virus
  • high resolution
  • clinical trial
  • randomized controlled trial
  • combination therapy
  • mass spectrometry
  • replacement therapy